Author results

1Y26
  • Download 1y26
  • View 1y26
Molmil generated image of 1y26
A-RIBOSWITCH-ADENINE COMPLEX
Descriptor:Vibrio vulnificus A-riboswitch, MAGNESIUM ION, ADENINE
Authors:Serganov, A., Yuan, Y.R., Patel, D.J.
Deposit date:2004-11-20
Release date:2004-12-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural Basis for Discriminative Regulation of Gene Expression by Adenine- and Guanine-Sensing mRNAs
Chem.Biol., 11, 2004
1Y27
  • Download 1y27
  • View 1y27
Molmil generated image of 1y27
G-RIBOSWITCH-GUANINE COMPLEX
Descriptor:Bacillus subtilis xpt, GUANINE
Authors:Serganov, A., Yuan, Y.R., Patel, D.J.
Deposit date:2004-11-20
Release date:2004-12-28
Last modified:2019-02-27
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural Basis for Discriminative Regulation of Gene Expression by Adenine- and Guanine-Sensing mRNAs
Chem.Biol., 11, 2004
1YKQ
  • Download 1ykq
  • View 1ykq
Molmil generated image of 1ykq
CRYSTAL STRUCTURE OF DIELS-ALDER RIBOZYME
Descriptor:Diels-Alder ribozyme, CADMIUM ION, MAGNESIUM ION
Authors:Serganov, A., Keiper, S., Malinina, L., Tereshko, V., Skripkin, E., Hobartner, C., Polonskaia, A., Phan, A.T., Wombacher, R., Micura, R., Dauter, Z., Jaschke, A., Patel, D.J.
Deposit date:2005-01-18
Release date:2005-02-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structural basis for Diels-Alder ribozyme-catalyzed carbon-carbon bond formation.
Nat.Struct.Mol.Biol., 12, 2005
1YKV
  • Download 1ykv
  • View 1ykv
Molmil generated image of 1ykv
CRYSTAL STRUCTURE OF THE DIELS-ALDER RIBOZYME COMPLEXED WITH THE PRODUCT OF THE REACTION BETWEEN N-PENTYLMALEIMIDE AND COVALENTLY ATTACHED 9-HYDROXYMETHYLANTHRACENE
Descriptor:Diels-Alder ribozyme, (3AS,9AS)-2-PENTYL-4-HYDROXYMETHYL-3A,4,9,9A-TETRAHYDRO-4,9[1',2']-BENZENO-1H-BENZ[F]ISOINDOLE-1,3(2H)-DIONE, MAGNESIUM ION
Authors:Serganov, A., Keiper, S., Malinina, L., Tereshko, V., Skripkin, E., Hobartner, C., Polonskaia, A., Phan, A.T., Wombacher, R., Micura, R., Dauter, Z., Jaschke, A., Patel, D.J.
Deposit date:2005-01-18
Release date:2005-02-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structural basis for Diels-Alder ribozyme-catalyzed carbon-carbon bond formation.
Nat.Struct.Mol.Biol., 12, 2005
1YLS
  • Download 1yls
  • View 1yls
Molmil generated image of 1yls
CRYSTAL STRUCTURE OF SELENIUM-MODIFIED DIELS-ALDER RIBOZYME COMPLEXED WITH THE PRODUCT OF THE REACTION BETWEEN N-PENTYLMALEIMIDE AND COVALENTLY ATTACHED 9-HYDROXYMETHYLANTHRACENE
Descriptor:RNA Diels-Alder ribozyme, (3AS,9AS)-2-PENTYL-4-HYDROXYMETHYL-3A,4,9,9A-TETRAHYDRO-4,9[1',2']-BENZENO-1H-BENZ[F]ISOINDOLE-1,3(2H)-DIONE, MAGNESIUM ION
Authors:Serganov, A., Keiper, S., Malinina, L., Tereshko, V., Skripkin, E., Hobartner, C., Polonskaia, A., Phan, A.T., Wombacher, R., Micura, R., Dauter, Z., Jaschke, A., Patel, D.J.
Deposit date:2005-01-19
Release date:2005-02-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural basis for Diels-Alder ribozyme-catalyzed carbon-carbon bond formation.
Nat.Struct.Mol.Biol., 12, 2005
2H1M
  • Download 2h1m
  • View 2h1m
Molmil generated image of 2h1m
SYNTHESIS, OXIDATION BEHAVIOR, CRYSTALLIZATION AND STRUCTURE OF 2'-METHYLSELENO GUANOSINE CONTAINING RNAS
Descriptor:5'-R(*GP*CP*AP*(XUG)P*AP*GP*UP*UP*AP*AP*AP*UP*CP*UP*GP*C)-3', SULFATE ION
Authors:Serganov, A.A.
Deposit date:2006-05-16
Release date:2006-07-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Synthesis, Oxidation Behavior, Crystallization and Structure of 2'-Methylseleno Guanosine Containing RNAs.
J.Am.Chem.Soc., 128, 2006
2Q1O
  • Download 2q1o
  • View 2q1o
Molmil generated image of 2q1o
CRYSTAL STRUCTURE ANALYSIS OF THE RNA DODECAMER CGC-NF2-AAUUGGCG, WITH AN INCORPORATED 2,4-DIFLUOROTOLUYL RESIDUE (NF2)
Descriptor:RNA (5'-R(*CP*GP*CP*(NF2)P*AP*AP*UP*UP*GP*GP*CP*G)-3')
Authors:Li, F., Pallan, P.S.
Deposit date:2007-05-25
Release date:2007-10-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Crystal structure, stability and in vitro RNAi activity of oligoribonucleotides containing the ribo-difluorotoluyl nucleotide: insights into substrate requirements by the human RISC Ago2 enzyme.
Nucleic Acids Res., 35, 2007
2Q1R
  • Download 2q1r
  • View 2q1r
Molmil generated image of 2q1r
CRYSTAL STRUCTURE ANALYSIS OF THE RNA DODECAMER CGCGAAUUAGCG, WITH A G-A MISMATCH.
Descriptor:RNA (5'-R(*CP*GP*CP*GP*AP*AP*UP*UP*AP*GP*CP*G)-3'), MAGNESIUM ION
Authors:Li, F., Pallan, P.S.
Deposit date:2007-05-25
Release date:2007-10-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.12 Å)
Cite:Crystal structure, stability and in vitro RNAi activity of oligoribonucleotides containing the ribo-difluorotoluyl nucleotide: insights into substrate requirements by the human RISC Ago2 enzyme.
Nucleic Acids Res., 35, 2007
2QEK
  • Download 2qek
  • View 2qek
Molmil generated image of 2qek
HIV-1 SUBTYPE F DIS RNA EXTENDED DUPLEX FORM
Descriptor:HIV-1 subtype F DIS genomic RNA, POTASSIUM ION, MAGNESIUM ION
Authors:Freisz, S., Ennifar, E., Dumas, P.
Deposit date:2007-06-26
Release date:2008-05-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Binding of aminoglycoside antibiotics to the duplex form of the HIV-1 genomic RNA dimerization initiation site.
Angew.Chem.Int.Ed.Engl., 47, 2008
3C3Z
  • Download 3c3z
  • View 3c3z
Molmil generated image of 3c3z
CRYSTAL STRUCTURE OF HIV-1 SUBTYPE F DIS EXTENDED DUPLEX RNA BOUND TO RIBOSTAMYCIN
Descriptor:HIV-1 subtype F genomic RNA, RIBOSTAMYCIN
Authors:Freisz, S., Lang, K., Micura, R., Dumas, P., Ennifar, E.
Deposit date:2008-01-29
Release date:2008-05-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Binding of aminoglycoside antibiotics to the duplex form of the HIV-1 genomic RNA dimerization initiation site.
Angew.Chem.Int.Ed.Engl., 47, 2008
3C44
  • Download 3c44
  • View 3c44
Molmil generated image of 3c44
CRYSTAL STRUCTURE OF HIV-1 SUBTYPE F DIS EXTENDED DUPLEX RNA BOUND TO PAROMOMYCIN
Descriptor:HIV-1 subtype F genomic RNA, PAROMOMYCIN, POTASSIUM ION, ...
Authors:Freisz, S., Ennifar, E., Dumas, P.
Deposit date:2008-01-29
Release date:2008-05-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Binding of aminoglycoside antibiotics to the duplex form of the HIV-1 genomic RNA dimerization initiation site.
Angew.Chem.Int.Ed.Engl., 47, 2008
3C5D
  • Download 3c5d
  • View 3c5d
Molmil generated image of 3c5d
CRYSTAL STRUCTURE OF HIV-1 SUBTYPE F DIS EXTENDED DUPLEX RNA BOUND TO LIVIDOMYCIN
Descriptor:'HIV-1 subtype F genomic RNA, POTASSIUM ION, (2R,3S,4S,5S,6R)-2-((2S,3S,4R,5R,6R)-5-AMINO-2-(AMINOMETHYL)-6-((2R,3S,4R,5S)-5-((1R,2R,3S,5R,6S)-3,5-DIAMINO-2-((2S,3R,5S,6R)-3-AMINO-5-HYDROXY-6-(HYDROXYMETHYL)-TETRAHYDRO-2H-PYRAN-2-YLOXY)-6-HYDROXYCYCLOHEXYLOXY)-4-HYDROXY-2-(HYDROXYMETHYL)-TETRAHYDROFURAN-3-YLOXY)-4-HYDROXY-TETRAHYDRO-2H-PYRAN-3-YLOXY)-6-(HYDROXYMETHYL)-TETRAHYDRO-2H-PYRAN-3,4,5-TRIOL
Authors:Freisz, S., Lang, K., Micura, R., Dumas, P., Ennifar, E.
Deposit date:2008-01-31
Release date:2008-05-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Binding of aminoglycoside antibiotics to the duplex form of the HIV-1 genomic RNA dimerization initiation site.
Angew.Chem.Int.Ed.Engl., 47, 2008
3C7R
  • Download 3c7r
  • View 3c7r
Molmil generated image of 3c7r
CRYSTAL STRUCTURE OF HIV-1 SUBTYPE F DIS EXTENDED DUPLEX RNA BOUND TO NEOMYCIN
Descriptor:HIV-1 subtype F genomic RNA, NEOMYCIN, POTASSIUM ION
Authors:Freisz, S., Lang, K., Micura, R., Dumas, P., Ennifar, E.
Deposit date:2008-02-08
Release date:2008-05-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Binding of aminoglycoside antibiotics to the duplex form of the HIV-1 genomic RNA dimerization initiation site.
Angew.Chem.Int.Ed.Engl., 47, 2008
3DVV
  • Download 3dvv
  • View 3dvv
Molmil generated image of 3dvv
CRYSTAL STRUCTURE OF HIV-1 SUBTYPE F DIS EXTENDED DUPLEX RNA BOUND TO RIBOSTAMYCIN (U267OME)
Descriptor:HIV-1 genomic RNA, POTASSIUM ION, CHLORIDE ION, ...
Authors:Ennifar, E., Dumas, P., Olieric, V.
Deposit date:2008-07-21
Release date:2008-08-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:A fast strategy for Selenium derivatization and phasing of RNA structures
To be Published
3CJZ
  • Download 3cjz
  • View 3cjz
Molmil generated image of 3cjz
EFFECTS OF N2,N2-DIMETHYLGUANOSINE ON RNA STRUCTURE AND STABILITY: CRYSTAL STRUCTURE OF AN RNA DUPLEX WITH TANDEM M22G:A PAIRS
Descriptor:RNA (5'-R(*GP*GP*AP*CP*GP*(M2G)P*AP*CP*GP*UP*CP*CP*U)-3')
Authors:Pallan, P.S., Kreutz, C., Bosio, S., Micura, R., Egli, M.
Deposit date:2008-03-14
Release date:2008-10-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Effects of N2,N2-dimethylguanosine on RNA structure and stability: crystal structure of an RNA duplex with tandem m2 2G:A pairs.
Rna, 14, 2008
3DVZ
  • Download 3dvz
  • View 3dvz
Molmil generated image of 3dvz
CRYSTAL STRUCTURE OF THE SARCIN/RICIN DOMAIN FROM E. COLI 23 S RRNA
Descriptor:Sarcin/Ricin Domain from E. Coli 23 S rRNA, GLYCEROL
Authors:Olieric, V., Rieder, U., Lang, K., Serganov, A., Schulze-Briese, C., Micura, R., Dumas, P., Ennifar, E.
Deposit date:2008-07-21
Release date:2009-03-24
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1 Å)
Cite:A fast selenium derivatization strategy for crystallization and phasing of RNA structures.
Rna, 15, 2009
3DW4
  • Download 3dw4
  • View 3dw4
Molmil generated image of 3dw4
CRYSTAL STRUCTURE OF THE SARCIN/RICIN DOMAIN FROM E. COLI 23 S RRNA, U2650-OCH3 MODIFIED
Descriptor:Sarcin/Ricin Domain from E. Coli 23 S rRNA, GLYCEROL
Authors:Olieric, V., Rieder, U., Lang, K., Serganov, A., Schulze-Briese, C., Micura, R., Dumas, P., Ennifar, E.
Deposit date:2008-07-21
Release date:2009-03-24
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (0.97 Å)
Cite:A fast selenium derivatization strategy for crystallization and phasing of RNA structures.
Rna, 15, 2009
3DW5
  • Download 3dw5
  • View 3dw5
Molmil generated image of 3dw5
CRYSTAL STRUCTURE OF THE SARCIN/RICIN DOMAIN FROM E. COLI 23S RRNA, U2656-OCH3 MODIFIED
Descriptor:Sarcin/Ricin Domain from E. Coli 23 S rRNA
Authors:Olieric, V., Rieder, U., Lang, K., Serganov, A., Schulze-Briese, C., Micura, R., Dumas, P., Ennifar, E.
Deposit date:2008-07-21
Release date:2009-03-24
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (0.96 Å)
Cite:A fast selenium derivatization strategy for crystallization and phasing of RNA structures.
Rna, 15, 2009
3DW6
  • Download 3dw6
  • View 3dw6
Molmil generated image of 3dw6
CRYSTAL STRUCTURE OF THE SARCIN/RICIN DOMAIN FROM E. COLI 23 S RRNA, U2650-SECH3 MODIFIED
Descriptor:Sarcin/Ricin Domain from E. Coli 23 S rRNA, GLYCEROL
Authors:Olieric, V., Rieder, U., Lang, K., Serganov, A., Schulze-Briese, C., Micura, R., Dumas, P., Ennifar, E.
Deposit date:2008-07-21
Release date:2009-03-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1 Å)
Cite:A fast selenium derivatization strategy for crystallization and phasing of RNA structures.
Rna, 15, 2009
3DW7
  • Download 3dw7
  • View 3dw7
Molmil generated image of 3dw7
CRYSTAL STRUCTURE OF THE SARCIN/RICIN DOMAIN FROM E. COLI 23 S RRNA, U2656-SECH3 MODIFIED
Descriptor:Sarcin/Ricin Domain from E. Coli 23 S rRNA
Authors:Olieric, V., Rieder, U., Lang, K., Serganov, A., Schulze-Briese, C., Micura, R., Dumas, P., Ennifar, E.
Deposit date:2008-07-21
Release date:2009-03-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1 Å)
Cite:A fast selenium derivatization strategy for crystallization and phasing of RNA structures.
Rna, 15, 2009
3NCU
  • Download 3ncu
  • View 3ncu
Molmil generated image of 3ncu
STRUCTURAL AND FUNCTIONAL INSIGHTS INTO PATTERN RECOGNITION BY THE INNATE IMMUNE RECEPTOR RIG-I
Descriptor:RIG-I, 5'-R(*(GDP)P*AP*CP*GP*CP*UP*AP*GP*CP*GP*UP*C)-3', ZINC ION
Authors:Sheng, G., Li, H.
Deposit date:2010-06-05
Release date:2010-06-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Structural and functional insights into 5'-ppp RNA pattern recognition by the innate immune receptor RIG-I.
Nat.Struct.Mol.Biol., 17, 2010
3S7C
  • Download 3s7c
  • View 3s7c
Molmil generated image of 3s7c
CRYSTAL STRUCTURE OF A 2'-AZIDO-URIDINE-MODIFIED RNA
Descriptor:Ecoli 23 S rRNA Sarcin Ricin loop
Authors:Ennifar, E., Micura, R.
Deposit date:2011-05-26
Release date:2012-04-11
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:2'-Azido RNA, a Versatile Tool for Chemical Biology: Synthesis, X-ray Structure, siRNA Applications, Click Labeling.
Acs Chem.Biol., 7, 2012
3S8U
  • Download 3s8u
  • View 3s8u
Molmil generated image of 3s8u
CRYSTAL STRUCTURE OF A 2-AZIDO-ADENINE-MODIFIED RNA
Descriptor:Ecoli 23 S rRNA Sarcin Ricin loop
Authors:Ennifar, E., Micura, R.
Deposit date:2011-05-31
Release date:2012-04-11
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:2'-Azido RNA, a Versatile Tool for Chemical Biology: Synthesis, X-ray Structure, siRNA Applications, Click Labeling.
Acs Chem.Biol., 7, 2012
4NLF
  • Download 4nlf
  • View 4nlf
Molmil generated image of 4nlf
2'-TRIFLUOROMETHYLTHIO-2'-DEOXYCYTIDINE-MODIFIED SRL
Descriptor:23S ribosomal RNA Sarcin Ricin Loop, SULFATE ION
Authors:Ennifar, E., Micura, R., Kosutic, M.
Deposit date:2013-11-14
Release date:2014-11-19
Method:X-RAY DIFFRACTION (1 Å)
Cite:2'-Trifluoromethylthio-modified RNA: synthesis, X-ray structure, thermodynamic analysis, and applications
To be Published
4NMG
  • Download 4nmg
  • View 4nmg
Molmil generated image of 4nmg
2'-TRIFLUOROMETHYLTHIO-2'-DEOXYURIDINE-MODIFIED SRL
Descriptor:23S ribosomal RNA Sarcin Ricin Loop
Authors:Ennifar, E., Micura, R., Kosutic, M.
Deposit date:2013-11-15
Release date:2014-11-19
Method:X-RAY DIFFRACTION (1.01 Å)
Cite:2'-Trifluoromethylthio-modified RNA: synthesis, X-ray structure, thermodynamic analysis, and applications
To be Published
<12>