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5WZZ
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BU of 5wzz by Molmil
The SIAH E3 ubiquitin ligases promote Wnt/ beta-catenin signaling through mediating Wnt-induced Axin degradation
Descriptor: Axin-1, E3 ubiquitin-protein ligase SIAH1, ZINC ION
Authors:Ji, L, Jiang, B, Jiang, X, Charlat, O, Chen, A, Mickanin, C, Bauer, A, Xu, W, Yan, X.-X, Cong, F.
Deposit date:2017-01-19
Release date:2017-08-16
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.103 Å)
Cite:The SIAH E3 ubiquitin ligases promote Wnt/ beta-catenin signaling through mediating Wnt-induced Axin degradation
Genes Dev., 31, 2017
8PD6
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BU of 8pd6 by Molmil
Crystal structure of the TRIM58 PRY-SPRY domain in complex with TRIM-473
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, E3 ubiquitin-protein ligase TRIM58, ...
Authors:Renatus, M, Hoegenauer, K, Schroeder, M.
Deposit date:2023-06-11
Release date:2024-01-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Discovery of Ligands for TRIM58, a Novel Tissue-Selective E3 Ligase.
Acs Med.Chem.Lett., 14, 2023
8PD4
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BU of 8pd4 by Molmil
Crystal structure of TRIM58 PRY-SPRY domain
Descriptor: E3 ubiquitin-protein ligase TRIM58
Authors:Renatus, M, Schroeder, M.
Deposit date:2023-06-11
Release date:2024-01-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.714 Å)
Cite:Discovery of Ligands for TRIM58, a Novel Tissue-Selective E3 Ligase.
Acs Med.Chem.Lett., 14, 2023
5FA5
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BU of 5fa5 by Molmil
Crystal Structure of PRMT5:MEP50 in complex with MTA and H4 peptide
Descriptor: 5'-DEOXY-5'-METHYLTHIOADENOSINE, Histone H4, Methylosome protein 50, ...
Authors:Sprague, E.R, McNamara, J.T.
Deposit date:2015-12-10
Release date:2016-02-24
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.34 Å)
Cite:Disordered methionine metabolism in MTAP/CDKN2A-deleted cancers leads to dependence on PRMT5.
Science, 351, 2016

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PDB entries from 2024-03-27

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