Author results

4P8Z
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SPECIATION OF A GROUP I INTRON INTO A LARIAT CAPPING RIBOZYME
分子名称:Didymium iridis partial IGS, 18S rRNA gene, I-DirI gene and partial ITS1
著者Meyer, M., Nielsen, H., Olieric, V., Roblin, P., Johansen, S.D., Westhof, E., Masquida, B.
登録日2014-04-01
公開日2014-05-28
最終更新日2017-10-04
実験手法X-RAY DIFFRACTION (3.85 Å)
主引用文献Speciation of a group I intron into a lariat capping ribozyme.
Proc.Natl.Acad.Sci.USA, 111, 2014
4P95
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SPECIATION OF A GROUP I INTRON INTO A LARIAT CAPPING RIBOZYME (CIRCULARLY PERMUTATED RIBOZYME)
分子名称:RNA (192-MER), 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, MAGNESIUM ION, ...
著者Meyer, M., Nielsen, H., Olieric, V., Roblin, P., Johansen, S.D., Westhof, E., Masquida, B.
登録日2014-04-02
公開日2014-05-28
最終更新日2017-10-04
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Speciation of a group I intron into a lariat capping ribozyme.
Proc.Natl.Acad.Sci.USA, 111, 2014
4P9R
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SPECIATION OF A GROUP I INTRON INTO A LARIAT CAPPING RIBOZYME (HEAVY ATOM DERIVATIVE)
分子名称:RNA (189-MER), IRIDIUM HEXAMMINE ION, MAGNESIUM ION
著者Meyer, M., Nielsen, H., Olieric, V., Roblin, P., Johansen, S.D., Westhof, E., Masquida, B.
登録日2014-04-04
公開日2014-05-28
最終更新日2017-10-04
実験手法X-RAY DIFFRACTION (2.703 Å)
主引用文献Speciation of a group I intron into a lariat capping ribozyme.
Proc.Natl.Acad.Sci.USA, 111, 2014
6GYV
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LARIAT-CAPPING RIBOZYME (CIRCULAR PERMUTATION FORM)
分子名称:Lariat-capping ribozyme, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, MAGNESIUM ION, ...
著者Masquida, B., Meyer, M., Nielsen, H., Olieric, V., Roblin, P., Johansen, S.D., Westhof, E.
登録日2018-07-02
公開日2018-08-22
実験手法X-RAY DIFFRACTION (2.500036 Å), SOLUTION SCATTERING
主引用文献Speciation of a group I intron into a lariat capping ribozyme.
Proc. Natl. Acad. Sci. U.S.A., 111, 2014
1L5Y
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CRYSTAL STRUCTURE OF MG2+ / BEF3-BOUND RECEIVER DOMAIN OF SINORHIZOBIUM MELILOTI DCTD
分子名称:C4-DICARBOXYLATE TRANSPORT TRANSCRIPTIONAL REGULATORY PROTEIN DCTD, MAGNESIUM ION, SULFATE ION, ...
著者Park, S., Meyer, M., Jones, A.D., Yennawar, H.P., Yennawar, N.H., Nixon, B.T.
登録日2002-03-08
公開日2002-10-23
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Two-component signaling in the AAA + ATPase DctD: binding Mg2+ and BeF3- selects between alternate dimeric states of the receiver domain
FASEB J., 16, 2002
1L5Z
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CRYSTAL STRUCTURE OF THE E121K SUBSTITUTION OF THE RECEIVER DOMAIN OF SINORHIZOBIUM MELILOTI DCTD
分子名称:C4-DICARBOXYLATE TRANSPORT TRANSCRIPTIONAL REGULATORY PROTEIN DCTD, SULFATE ION, GLYCEROL
著者Park, S., Meyer, M., Jones, A.D., Yennawar, H.P., Yennawar, N.H., Nixon, B.T.
登録日2002-03-08
公開日2002-10-23
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Two-component signaling in the AAA + ATPase DctD: binding Mg2+ and BeF3- selects between alternate dimeric states of the receiver domain
FASEB J., 16, 2002
6G7Z
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LARIAT-CAPPING RIBOZYME WITH A SHORTENED DP2 STEM LOOP
分子名称:Lariat-capping ribozyme, MAGNESIUM ION, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID
著者Masquida, B., Meyer, M., Olieric, V.
登録日2018-04-06
公開日2018-12-05
実験手法X-RAY DIFFRACTION (3.33595 Å)
主引用文献Lariat-capping ribozyme with a shortened DP2 stem loop
To Be Published
3G8I
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ALEGLITAZAR, A NEW, POTENT, AND BALANCED PPAR ALPHA/GAMMA AGONIST FOR THE TREATMENT OF TYPE II DIABETES
分子名称:Peroxisome proliferator-activated receptor alpha, Nuclear receptor coactivator 1, (2S)-2-methoxy-3-{4-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethoxy]-1-benzothiophen-7-yl}propanoic acid
著者Benz, J., Bernardeau, A., Binggeli, A., Blum, D., Boehringer, M., Grether, U., Hilpert, H., Kuhn, B., Maerki, H.P., Meyer, M., Puentener, K., Raab, S., Ruf, A., Schlatter, D., Gsell, B., Stihle, M., Mohr, P.
登録日2009-02-12
公開日2009-06-02
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Aleglitazar, a new, potent, and balanced dual PPARalpha/gamma agonist for the treatment of type II diabetes.
Bioorg.Med.Chem.Lett., 19, 2009
3G9E
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ALEGLITAAR. A NEW. POTENT, AND BALANCED DUAL PPARA/G AGONIST FOR THE TREATMENT OF TYPE II DIABETES
分子名称:Peroxisome proliferator-activated receptor gamma, Nuclear receptor coactivator 1, (2S)-2-methoxy-3-{4-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethoxy]-1-benzothiophen-7-yl}propanoic acid
著者Ruf, A., Benz, J., Bernardeau, A., Binggeli, A., Blum, D., Boehringer, M., Grether, U., Hilpert, H., Kuhn, B., Maerki, H.P., Meyer, M., Puenterner, K., Raab, S., Schlatter, D., Gsell, B., Stihle, M., Mohr, P.
登録日2009-02-13
公開日2009-06-02
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Aleglitazar, a new, potent, and balanced dual PPARalpha/gamma agonist for the treatment of type II diabetes.
Bioorg.Med.Chem.Lett., 19, 2009
5MEI
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CRYSTAL STRUCTURE OF AGELASTATIN A BOUND TO THE 80S RIBOSOME
分子名称:25S ribosomal RNA, 5S ribosomal RNA, 5.8S ribosomal RNA, ...
著者McClary, B., Zinshteyn, B., Meyer, M., Jouanneau, M., Pellegrino, S., Yusupova, G., Schuller, A., Reyes, J.C.P., Lu, J., Luo, C., Dang, Y., Romo, D., Yusupov, M., Green, R., Liu, J.O.
登録日2016-11-15
公開日2017-06-28
最終更新日2018-01-31
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Inhibition of Eukaryotic Translation by the Antitumor Natural Product Agelastatin A.
Cell Chem Biol, 24, 2017
2FVJ
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A NOVEL ANTI-ADIPOGENIC PARTIAL AGONIST OF PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR-GAMMA (PPARG) RECRUITS PPARG-COACTIVATOR-1 ALPHA (PGC1A) BUT POTENTIATES INSULIN SIGNALING IN VITRO
分子名称:Peroxisome proliferator-activated receptor gamma, Nuclear receptor coactivator 1, 1-(3,4-DIMETHOXYBENZYL)-6,7-DIMETHOXY-4-{[4-(2-METHOXYPHENYL)PIPERIDIN-1-YL]METHYL}ISOQUINOLINE, ...
著者Benz, J., Burgermeister, E., Flament, A., Schnoebelen, A., Stihle, M., Gsell, B., Rufer, A., Ruf, A., Kuhn, B., Maerki, H.P., Mizrahi, J., Sebokova, E., Niesor, E., Meyer, M.
登録日2006-01-31
公開日2006-05-16
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献A novel partial agonist of peroxisome proliferator-activated receptor-gamma (PPARgamma) recruits PPARgamma-coactivator-1alpha, prevents triglyceride accumulation, and potentiates insulin signaling in vitro
Mol.Endocrinol., 20, 2006
5ON6
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CRYSTAL STRUCTURE OF HAEMANTHAMINE BOUND TO THE 80S RIBOSOME
分子名称:25S ribosomal RNA, 5S ribosomal RNA, 5.8S ribosomal RNA, ...
著者Pellegrino, S., Meyer, M., Yusupova, G., Yusupov, M.
登録日2017-08-03
公開日2018-02-28
最終更新日2018-03-14
実験手法X-RAY DIFFRACTION (3.100002 Å)
主引用文献The Amaryllidaceae Alkaloid Haemanthamine Binds the Eukaryotic Ribosome to Repress Cancer Cell Growth.
Structure, 26, 2018
5TBW
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CRYSTAL STRUCTURE OF CHLOROLISSOCLIMIDE BOUND TO THE YEAST 80S RIBOSOME
分子名称:25S ribosomal RNA, 5S ribosomal RNA, 5.8S ribosomal RNA, ...
著者Konst, Z.A., Szklarski, A.R., Pellegrino, S., Michalak, S.E., Meyer, M., Zanette, C., Cencic, R., Nam, S., Horne, D.A., Pelletier, J., Mobley, D.L., Yusupova, G., Yusupov, M., Vanderwal, C.D.
登録日2016-09-13
公開日2017-07-26
最終更新日2018-08-08
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Synthesis facilitates an understanding of the structural basis for translation inhibition by the lissoclimides.
Nat Chem, 9, 2017
2GTK
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STRUCTURE-BASED DESIGN OF INDOLE PROPIONIC ACIDS AS NOVEL PPARAG CO-AGONISTS
分子名称:Peroxisome proliferator-activated receptor gamma, Decamer from Nuclear receptor coactivator 1, (2S)-3-(1-{[2-(2-CHLOROPHENYL)-5-METHYL-1,3-OXAZOL-4-YL]METHYL}-1H-INDOL-5-YL)-2-ETHOXYPROPANOIC ACID
著者Kuhn, B., Hilpert, H., Benz, J., Binggeli, A., Grether, U., Humm, R., Maerki, H.-P., Meyer, M., Mohr, P.
登録日2006-04-28
公開日2006-09-26
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structure-based design of indole propionic acids as novel PPARalpha/gamma co-agonists
Bioorg.Med.Chem.Lett., 16, 2006
4AQY
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STRUCTURE OF RIBOSOME-APRAMYCIN COMPLEXES
分子名称:16S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S2, 30S RIBOSOMAL PROTEIN S3, ...
著者Matt, T., Ng, C.L., Lang, K., Sha, S.H., Akbergenov, R., Shcherbakov, D., Meyer, M., Duscha, S., Xie, J., Dubbaka, S.R., Perez-Fernandez, D., Vasella, A., Ramakrishnan, V., Schacht, J., Bottger, E.C.
登録日2012-04-20
公開日2012-07-18
最終更新日2019-05-22
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Dissociation of Antibacterial Activity and Aminoglycoside Ototoxicity in the 4-Monosubstituted 2-Deoxystreptamine Apramycin.
Proc.Natl.Acad.Sci.USA, 109, 2012
4B3M
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CRYSTAL STRUCTURE OF THE 30S RIBOSOME IN COMPLEX WITH COMPOUND 1
分子名称:16S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S2, 30S RIBOSOMAL PROTEIN S3, ...
著者Ng, C.L., Lang, K., Shcherbakov, D., Matt, T., Perez-Fernandez, D., Patak, R., Meyer, M., Duscha, S., Akbergenov, R., Boukari, H., Freihofer, P., Kudyba, I., Reddy, M.S.K., Nandurikar, R.S., Ramakrishnan, V., Vasella, A., Bottger, E.C.
登録日2012-07-25
公開日2013-08-07
最終更新日2019-03-06
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献4'-O-Substitutions Determine Selectivity of Aminoglycoside Antibiotics
Nat.Commun., 5, 2014
4B3R
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CRYSTAL STRUCTURE OF THE 30S RIBOSOME IN COMPLEX WITH COMPOUND 30
分子名称:16S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S2, 30S RIBOSOMAL PROTEIN S3, ...
著者Ng, C.L., Lang, K., Shcherbakov, D., Matt, T., Perez-Fernandez, D., Patak, R., Meyer, M., Duscha, S., Akbergenov, R., Boukari, H., Freihofer, P., Kudyba, I., Reddy, M.S.K., Nandurikar, R.S., Ramakrishnan, V., Vasella, A., Bottger, E.C.
登録日2012-07-26
公開日2013-08-07
最終更新日2019-05-22
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献4'-O-Substitutions Determine Selectivity of Aminoglycoside Antibiotics
Nat.Commun., 5, 2014
4B3S
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CRYSTAL STRUCTURE OF THE 30S RIBOSOME IN COMPLEX WITH COMPOUND 37
分子名称:16S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S2, 30S RIBOSOMAL PROTEIN S3, ...
著者Ng, C.L., Lang, K., Shcherbakov, D., Matt, T., Perez-Fernandez, D., Patak, R., Meyer, M., Duscha, S., Akbergenov, R., Boukari, H., Freihofer, P., Kudyba, I., Reddy, M.S.K., Nandurikar, R.S., Ramakrishnan, V., Vasella, A., Bottger, E.C.
登録日2012-07-26
公開日2013-08-07
最終更新日2019-03-06
実験手法X-RAY DIFFRACTION (3.15 Å)
主引用文献4'-O-Substitutions Determine Selectivity of Aminoglycoside Antibiotics
Nat.Commun., 5, 2014
4B3T
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CRYSTAL STRUCTURE OF THE 30S RIBOSOME IN COMPLEX WITH COMPOUND 39
分子名称:16S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S2, 30S RIBOSOMAL PROTEIN S3, ...
著者Ng, C.L., Lang, K., Shcherbakov, D., Matt, T., Perez-Fernandez, D., Patak, R., Meyer, M., Duscha, S., Akbergenov, R., Boukari, H., Freihofer, P., Kudyba, I., Reddy, M.S.K., Nandurikar, R.S., Ramakrishnan, V., Vasella, A., Bottger, E.C.
登録日2012-07-26
公開日2013-08-07
最終更新日2019-03-06
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献4'-O-Substitutions Determine Selectivity of Aminoglycoside Antibiotics
Nat.Commun., 5, 2014
6HHQ
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CRYSTAL STRUCTURE OF COMPOUND C45 BOUND TO THE YEAST 80S RIBOSOME
分子名称:25S ribosomal RNA, 5S ribosomal RNA, 5.8S ribosomal RNA, ...
著者Pellegrino, S., Vanderwal, C.D., Yusupov, M.
登録日2018-08-28
公開日2019-02-20
最終更新日2019-04-17
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Understanding the role of intermolecular interactions between lissoclimides and the eukaryotic ribosome.
Nucleic Acids Res., 47, 2019
3FEI
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DESIGN AND BIOLOGICAL EVALUATION OF NOVEL, BALANCED DUAL PPARA/G AGONISTS
分子名称:Peroxisome proliferator-activated receptor alpha, Peptide motif 5 of Nuclear receptor coactivator 1, (2S)-3-(4-{[2-(4-chlorophenyl)-1,3-thiazol-4-yl]methoxy}-2-methylphenyl)-2-ethoxypropanoic acid
著者Benz, J., Grether, U., Gsell, B., Binggeli, A., Hilpert, H., Maerki, H.P., Mohr, P., Ruf, A., Stihle, M., Schlatter, D.
登録日2008-11-30
公開日2009-10-20
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Design and biological evaluation of novel, balanced dual PPARalpha/gamma agonists
Chemmedchem, 4, 2009
3FEJ
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DESIGN AND BIOLOGICAL EVALUATION OF NOVEL, BALANCED DUAL PPARA/G AGONISTS
分子名称:Peroxisome proliferator-activated receptor gamma, peptide motif 3 of Nuclear receptor coactivator 1, (2S)-3-(4-{[2-(4-chlorophenyl)-1,3-thiazol-4-yl]methoxy}-2-methylphenyl)-2-ethoxypropanoic acid
著者Benz, J., Grether, U., Gsell, B., Binggeli, A., Hilpert, H., Kuhn, B., Maerki, H.P., Mohr, P., Ruf, A., Stihle, M.
登録日2008-11-30
公開日2009-10-20
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献Design and biological evaluation of novel, balanced dual PPARalpha/gamma agonists
Chemmedchem, 4, 2009
1UYA
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THE SOLUTION STRUCTURE OF THE A-FORM OF UROGUANYLIN-16 NMR, 10 STRUCTURES
分子名称:UROGUANYLIN-16, ISOMER A
著者Marx, U.C., Adermann, K., Forssmann, W.-G., Roesch, P.
登録日1997-09-11
公開日1998-03-18
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献One peptide, two topologies: structure and interconversion dynamics of human uroguanylin isomers.
J.Pept.Res., 52, 1998
1UYB
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THE SOLUTION STRUCTURE OF THE B-FORM OF UROGUANYLIN-16 NMR, 10 STRUCTURES
分子名称:UROGUANYLIN-16, ISOMER B
著者Marx, U.C., Adermann, K., Forssmann, W.-G., Roesch, P.
登録日1997-09-11
公開日1998-03-18
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献One peptide, two topologies: structure and interconversion dynamics of human uroguanylin isomers.
J.Pept.Res., 52, 1998
1ZWB
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STRUCTURE OF HUMAN PARATHYROID HORMONE FRAGMENT 2-37, NMR, 10 STRUCTURES
分子名称:PARATHYROID HORMONE
著者Roesch, P., Marx, U.C.
登録日1996-06-17
公開日1997-03-12
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Structure-activity relation of NH2-terminal human parathyroid hormone fragments.
J.Biol.Chem., 273, 1998
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