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5W4K
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BU of 5w4k by Molmil
Crystal structure of the Thermus thermophilus 70S ribosome in complex with Klebsazolicin and bound to mRNA and A-, P- and E-site tRNAs at 2.7A resolution
Descriptor: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Metelev, M, Osterman, I.A, Ghilarov, D, Khabibullina, N.F, Yakimov, A, Shabalin, K, Utkina, I, Travin, D.Y, Komarova, E.S, Serebryakova, M, Artamonova, T, Khodorkovskii, M, Konevega, A.L, Sergiev, P.V, Severinov, K, Polikanov, Y.S.
Deposit date:2017-06-12
Release date:2017-08-30
Last modified:2019-12-04
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Klebsazolicin inhibits 70S ribosome by obstructing the peptide exit tunnel.
Nat. Chem. Biol., 13, 2017
2MW3
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Solution NMR structure of the lasso peptide streptomonomicin
Descriptor: Lasso peptide
Authors:Tietz, J.I, Zhu, L, Mitchell, D.A, Metelev, M, Melby, J.O, Blair, P.M, Livnat, I, Severinov, K.
Deposit date:2014-10-24
Release date:2015-01-28
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structure, bioactivity, and resistance mechanism of streptomonomicin, an unusual lasso Peptide from an understudied halophilic actinomycete.
Chem.Biol., 22, 2015
5UI7
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BU of 5ui7 by Molmil
Solution NMR Structure of Lasso Peptide Klebsidin
Descriptor: Klebsidin
Authors:Bushin, L.B, Metelev, M, Severinov, K, Seyedsayamdost, M.R.
Deposit date:2017-01-13
Release date:2017-02-08
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Acinetodin and Klebsidin, RNA Polymerase Targeting Lasso Peptides Produced by Human Isolates of Acinetobacter gyllenbergii and Klebsiella pneumoniae.
ACS Chem. Biol., 12, 2017
5UI6
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Solution NMR Structure of Lasso Peptide Acinetodin
Descriptor: Acinetodin
Authors:Bushin, L.B, Metelev, M, Severinov, K, Seyedsayamdost, M.R.
Deposit date:2017-01-12
Release date:2017-02-08
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Acinetodin and Klebsidin, RNA Polymerase Targeting Lasso Peptides Produced by Human Isolates of Acinetobacter gyllenbergii and Klebsiella pneumoniae.
ACS Chem. Biol., 12, 2017
6U48
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E. coli 50S with phazolicin (PHZ) bound in exit tunnel
Descriptor: 23S rRNA, 50S ribosomal protein bL17, 50S ribosomal protein bL19, ...
Authors:Watson, Z.L, Cate, J.H.D, Polikanov, Y.S, Severinov, K.
Deposit date:2019-08-23
Release date:2019-09-18
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (2.87 Å)
Cite:Structure of ribosome-bound azole-modified peptide phazolicin rationalizes its species-specific mode of bacterial translation inhibition.
Nat Commun, 10, 2019

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