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6GTC
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TRANSITION STATE STRUCTURE OF CPF1(CAS12A) I1 CONFORMATION
Descriptor:CRISPR-associated endonuclease Cas12a, RNA (28-MER), DNA (5'-D(P*TP*GP*AP*CP*TP*TP*CP*TP*CP*TP*AP*AP*CP*AP*AP*GP*CP*TP*CP*G)-3'), ...
Authors:Mesa, P., Montoya, G.
Deposit date:2018-06-18
Release date:2018-12-19
Last modified:2018-12-26
Method:ELECTRON MICROSCOPY (3.91 Å)
Cite:Conformational Activation Promotes CRISPR-Cas12a Catalysis and Resetting of the Endonuclease Activity.
Cell, 175, 2018
6GTG
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TRANSITION STATE STRUCTURE OF CPF1(CAS12A) I4 CONFORMATION
Descriptor:CRISPR-associated endonuclease Cas12a, RNA (40-MER), DNA (32-MER), ...
Authors:Mesa, P., Montoya, G., Stella, S.
Deposit date:2018-06-18
Release date:2018-12-19
Last modified:2018-12-26
Method:ELECTRON MICROSCOPY (3.27 Å)
Cite:Conformational Activation Promotes CRISPR-Cas12a Catalysis and Resetting of the Endonuclease Activity.
Cell, 175, 2018
6GTD
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TRANSIENT STATE STRUCTURE OF CRISPR-CPF1 (CAS12A) I2 CONFORMATION
Descriptor:CRISPR-associated endonuclease Cas12a, RNA (28-MER), DNA (5'-D(P*TP*GP*AP*CP*TP*TP*CP*TP*CP*TP*AP*AP*CP*AP*AP*GP*CP*TP*CP*G)-3'), ...
Authors:Montoya, G., Mesa, P.
Deposit date:2018-06-18
Release date:2018-12-19
Last modified:2018-12-26
Method:ELECTRON MICROSCOPY (4.24 Å)
Cite:Conformational Activation Promotes CRISPR-Cas12a Catalysis and Resetting of the Endonuclease Activity.
Cell, 175, 2018
6GTE
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TRANSIENT STATE STRUCTURE OF CRISPR-CPF1 (CAS12A) I3 CONFORMATION
Descriptor:CRISPR-associated endonuclease Cas12a, RNA (29-MER), DNA (5'-D(P*AP*TP*GP*AP*CP*TP*TP*CP*TP*CP*TP*AP*AP*CP*AP*AP*GP*CP*TP*CP*G)-3'), ...
Authors:Montoya, G., Mesa, P., Stella, S.
Deposit date:2018-06-18
Release date:2018-12-19
Last modified:2018-12-26
Method:ELECTRON MICROSCOPY (4.07 Å)
Cite:Conformational Activation Promotes CRISPR-Cas12a Catalysis and Resetting of the Endonuclease Activity.
Cell, 175, 2018
6GTF
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TRANSIENT STATE STRUCTURE OF CRISPR-CPF1 (CAS12A) I5 CONFORMATION
Descriptor:CRISPR-associated endonuclease Cas12a, RNA (29-MER), DNA (5'-D(P*AP*TP*GP*AP*CP*TP*TP*CP*TP*CP*TP*AP*AP*CP*AP*AP*GP*CP*TP*CP*G)-3'), ...
Authors:Montoya, G., Mesa, P., Stella, S.
Deposit date:2018-06-18
Release date:2018-12-19
Last modified:2018-12-26
Method:ELECTRON MICROSCOPY (3.63 Å)
Cite:Conformational Activation Promotes CRISPR-Cas12a Catalysis and Resetting of the Endonuclease Activity.
Cell, 175, 2018
1NO1
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STRUCTURE OF TRUNCATED VARIANT OF B.SUBTILIS SPP1 PHAGE G39P HELICASE LOADER/INHIBITOR PROTEIN
Descriptor:replisome organizer
Authors:Bailey, S., Sedelnikova, S.E., Mesa, P., Ayora, S., Waltho, J.P., Ashcroft, A.E., Baron, A.J., Alonso, J.C., Rafferty, J.B.
Deposit date:2003-01-15
Release date:2003-05-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural analysis of Bacillus subtilis SPP1 phage helicase loader protein G39P
J.Biol.Chem., 278, 2003
2XSM
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CRYSTAL STRUCTURE OF THE MAMMALIAN CYTOSOLIC CHAPERONIN CCT IN COMPLEX WITH TUBULIN
Descriptor:CCT
Authors:Munoz, I.G., Yebenes, H., Zhou, M., Mesa, P., Serna, M., Bragado-Nilsson, E., Beloso, A., Robinson, C.V., Valpuesta, J.M., Montoya, G.
Deposit date:2010-10-29
Release date:2010-12-15
Method:X-RAY DIFFRACTION (5.5 Å)
Cite:Crystal Structure of the Open Conformation of the Mammalian Chaperonin Cct in Complex with Tubulin.
Nat.Struct.Mol.Biol., 18, 2011
5JNO
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CRYSTAL STRUCTURE OF THE BD1-NTPR COMPLEX FROM BEND3 AND PICH
Descriptor:BEN domain-containing protein 3, DNA excision repair protein ERCC-6-like, GLYCEROL
Authors:Pitchai, G., Mesa, P., Hickson, I.D., Montoya, G.
Deposit date:2016-04-30
Release date:2017-09-13
Last modified:2019-10-16
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of the BD1-NTPR complex from BEND3 and PICH
To Be Published
6DTD
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HIGH-RESOLUTION CRYSTAL STRUCTURE OF CAS13B FROM PREVOTELLA BUCCAE
Descriptor:nuclease, RNA (37-MER), CITRIC ACID, ...
Authors:Slaymaker, I.M.S., Zhang, F.Z.
Deposit date:2018-06-15
Release date:2019-02-20
Last modified:2019-09-11
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:High-Resolution Structure of Cas13b and Biochemical Characterization of RNA Targeting and Cleavage.
Cell Rep, 26, 2019
4B2T
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THE CRYSTAL STRUCTURES OF THE EUKARYOTIC CHAPERONIN CCT REVEAL ITS FUNCTIONAL PARTITIONING
Descriptor:T-COMPLEX PROTEIN 1 SUBUNIT ALPHA, T-COMPLEX PROTEIN 1 SUBUNIT BETA, T-COMPLEX PROTEIN 1 SUBUNIT DELTA, ...
Authors:Kalisman, N., Schroeder, G.F., Levitt, M.
Deposit date:2012-07-17
Release date:2013-03-20
Last modified:2013-06-05
Method:X-RAY DIFFRACTION (5.5 Å)
Cite:The Crystal Structures of the Eukaryotic Chaperonin Cct Reveal its Functional Partitioning
Structure, 21, 2013