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6F7B
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CRYSTAL STRUCTURE OF THE HUMAN BUB1 KINASE DOMAIN IN COMPLEX WITH BAY 1816032
Descriptor:Mitotic checkpoint serine/threonine-protein kinase BUB1, 2-[3,5-bis(fluoranyl)-4-[[3-[5-methoxy-4-[(3-methoxypyridin-4-yl)amino]pyrimidin-2-yl]indazol-1-yl]methyl]phenoxy]ethanol, MAGNESIUM ION
Authors:Holton, S.J., Siemeister, G., Mengel, A., Bone, W., Schroeder, J., Zitzmann-Kolbe, S., Briem, H., Fernandez-Montalvan, A., Prechtl, S., Moenning, U., von Ahsen, O., Johanssen, J., Cleve, A., Puetter, V., Hitchcock, M., von Nussbaum, F., Brands, M., Mumberg, D., Ziegelbauer, K.
Deposit date:2017-12-08
Release date:2018-12-19
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of the human Bub1 kinase domain in complex with BAY 1816032
To be published
2JBO
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PROTEIN KINASE MK2 IN COMPLEX WITH AN INHIBITOR (CRYSTAL FORM-1, SOAKING)
Descriptor:MAP KINASE-ACTIVATED PROTEIN KINASE 2, PHOSPHATE ION, 2-(2-QUINOLIN-3-YLPYRIDIN-4-YL)-1,5,6,7-TETRAHYDRO-4H-PYRROLO[3,2-C]PYRIDIN-4-ONE
Authors:Hillig, R.C., Eberspaecher, U., Monteclaro, F., Huber, M., Nguyen, D., Mengel, A., Muller-Tiemann, B., Egner, U.
Deposit date:2006-12-09
Release date:2007-03-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural Basis for a High Affinity Inhibitor Bound to Protein Kinase Mk2.
J.Mol.Biol., 369, 2007
2JBP
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PROTEIN KINASE MK2 IN COMPLEX WITH AN INHIBITOR (CRYSTAL FORM-2, CO- CRYSTALLIZATION)
Descriptor:MAP KINASE-ACTIVATED PROTEIN KINASE 2, 2-(2-QUINOLIN-3-YLPYRIDIN-4-YL)-1,5,6,7-TETRAHYDRO-4H-PYRROLO[3,2-C]PYRIDIN-4-ONE
Authors:Hillig, R.C., Eberspaecher, U., Monteclaro, F., Huber, M., Nguyen, D., Mengel, A., Muller-Tiemann, B., Egner, U.
Deposit date:2006-12-09
Release date:2007-03-20
Last modified:2019-01-16
Method:X-RAY DIFFRACTION (3.31 Å)
Cite:Structural basis for a high affinity inhibitor bound to protein kinase MK2.
J. Mol. Biol., 369, 2007