Author results

3KAY
  • Download 3kay
  • View 3kay
Molmil generated image of 3kay
CRYSTAL STRUCTURE OF ABSCISIC ACID RECEPTOR PYL1
Descriptor:Putative uncharacterized protein At5g46790
Authors:Zhou, X.E., Melcher, K., Ng, L.-M., Soon, F.-F., Xu, Y., Suino-Powell, K.M., Kovach, A., Li, J., Xu, H.E.
Deposit date:2009-10-19
Release date:2009-12-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Agate-latch-lock mechanism for hormone signalling by abscisic acid receptors
Nature, 462, 2009
3KAZ
  • Download 3kaz
  • View 3kaz
Molmil generated image of 3kaz
CRYSTAL STRUCTURE OF ABSCISIC ACID RECEPTOR PYL2
Descriptor:Putative uncharacterized protein At2g26040, 1,3-BUTANEDIOL
Authors:Zhou, X.E., Melcher, K., Ng, L.-M., Soon, F.-F., Xu, Y., Suino-Powell, K.M., Kovach, A., Li, J., Xu, H.E.
Deposit date:2009-10-19
Release date:2009-12-08
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Agate-latch-lock mechanism for hormone signalling by abscisic acid receptors
Nature, 462, 2009
3KB0
  • Download 3kb0
  • View 3kb0
Molmil generated image of 3kb0
CRYSTAL STRUCTURE OF ABSCISIC ACID-BOUND PYL2
Descriptor:Putative uncharacterized protein At2g26040, (2Z,4E)-5-[(1S)-1-hydroxy-2,6,6-trimethyl-4-oxocyclohex-2-en-1-yl]-3-methylpenta-2,4-dienoic acid
Authors:Zhou, X.E., Melcher, K., Ng, L.-M., Soon, F.-F., Xu, Y., Suino-Powell, K.M., Kovach, A., Li, J., Xu, H.E.
Deposit date:2009-10-19
Release date:2009-12-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Agate-latch-lock mechanism for hormone signalling by abscisic acid receptors
Nature, 462, 2009
3KB3
  • Download 3kb3
  • View 3kb3
Molmil generated image of 3kb3
CRYSTAL STRUCTURE OF ABSCISIC ACID-BOUND PYL2 IN COMPLEX WITH HAB1
Descriptor:Putative uncharacterized protein At2g26040, Protein phosphatase 2C 16, (2Z,4E)-5-[(1S)-1-hydroxy-2,6,6-trimethyl-4-oxocyclohex-2-en-1-yl]-3-methylpenta-2,4-dienoic acid, ...
Authors:Zhou, X.E., Melcher, K., Soon, F.-F., Ng, L.-M., Xu, Y., Suino-Powell, K.M., Kovach, A., Li, J., Xu, H.E.
Deposit date:2009-10-20
Release date:2009-12-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Agate-latch-lock mechanism for hormone signalling by abscisic acid receptors
Nature, 462, 2009
3L3X
  • Download 3l3x
  • View 3l3x
Molmil generated image of 3l3x
CRYSTAL STRUCTURE OF DHT-BOUND ANDROGEN RECEPTOR IN COMPLEX WITH THE FIRST MOTIF OF STEROID RECEPTOR COACTIVATOR 3
Descriptor:Androgen receptor, Nuclear receptor coactivator 3, 5-ALPHA-DIHYDROTESTOSTERONE
Authors:Zhou, X.E., Suino-Powell, K.M., Li, J., He, A., MacKeigan, J.P., Melcher, K., Yong, E.-L., Xu, H.E.
Deposit date:2009-12-18
Release date:2010-01-12
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Identification of SRC3/AIB1 as a Preferred Coactivator for Hormone-activated Androgen Receptor.
J.Biol.Chem., 285, 2010
3L3Z
  • Download 3l3z
  • View 3l3z
Molmil generated image of 3l3z
CRYSTAL STRUCTURE OF DHT-BOUND ANDROGEN RECEPTOR IN COMPLEX WITH THE THIRD MOTIF OF STEROID RECEPTOR COACTIVATOR 3
Descriptor:Androgen receptor, Nuclear receptor coactivator 3, 5-ALPHA-DIHYDROTESTOSTERONE
Authors:Zhou, X.E., Suino-Powell, K.M., Li, J., He, A., MacKeigan, J.P., Melcher, K., Yong, E.-L., Xu, H.E.
Deposit date:2009-12-18
Release date:2010-01-12
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2 Å)
Cite:Identification of SRC3/AIB1 as a Preferred Coactivator for Hormone-activated Androgen Receptor.
J.Biol.Chem., 285, 2010
3NMH
  • Download 3nmh
  • View 3nmh
Molmil generated image of 3nmh
CRYSTAL STRUCTURE OF THE ABSCISIC RECEPTOR PYL2 IN COMPLEX WITH PYRABACTIN
Descriptor:Abscisic acid receptor PYL2, 4-bromo-N-(pyridin-2-ylmethyl)naphthalene-1-sulfonamide, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID
Authors:Zhou, X.E., Melcher, K., Ng, L.-M., Soon, F.-F., Xu, Y., Suino-Powell, K.M., Kovach, A., Li, J., Yong, E.-L., Xu, H.E.
Deposit date:2010-06-22
Release date:2010-08-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Identification and mechanism of ABA receptor antagonism.
Nat.Struct.Mol.Biol., 17, 2010
3NMN
  • Download 3nmn
  • View 3nmn
Molmil generated image of 3nmn
CRYSTAL STRUCTURE OF PYRABACTIN-BOUND ABSCISIC ACID RECEPTOR PYL1 IN COMPLEX WITH TYPE 2C PROTEIN PHOSPHATASE ABI1
Descriptor:Abscisic acid receptor PYL1, Protein phosphatase 2C 56, 4-bromo-N-(pyridin-2-ylmethyl)naphthalene-1-sulfonamide, ...
Authors:Zhou, X.E., Melcher, K., Ng, L.-M., Soon, F.-F., Xu, Y., Suino-Powell, K.M., Kovach, A., Li, J., Yong, E.-L., Xu, H.E.
Deposit date:2010-06-22
Release date:2010-08-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Identification and mechanism of ABA receptor antagonism.
Nat.Struct.Mol.Biol., 17, 2010
3NMP
  • Download 3nmp
  • View 3nmp
Molmil generated image of 3nmp
CRYSTAL STRUCTURE OF THE ABSCISIC RECEPTOR PYL2 MUTANT A93F IN COMPLEX WITH PYRABACTIN
Descriptor:Abscisic acid receptor PYL2, 4-bromo-N-(pyridin-2-ylmethyl)naphthalene-1-sulfonamide
Authors:Zhou, X.E., Melcher, K., Ng, L.-M., Soon, F.-F., Xu, Y., Suino-Powell, K.M., Kovach, A., Li, J., Yong, E.-L., Xu, H.E.
Deposit date:2010-06-22
Release date:2010-08-25
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Identification and mechanism of ABA receptor antagonism.
Nat.Struct.Mol.Biol., 17, 2010
3NMT
  • Download 3nmt
  • View 3nmt
Molmil generated image of 3nmt
CRYSTAL STRUCTURE OF PYRABACTIN BOUND ABSCISIC ACID RECEPTOR PYL2 MUTANT A93F IN COMPLEX WITH TYPE 2C PROTEIN PHOSPHATASE HAB1
Descriptor:Abscisic acid receptor PYL2, Protein phosphatase 2C 16, 4-bromo-N-(pyridin-2-ylmethyl)naphthalene-1-sulfonamide, ...
Authors:Zhou, X.E., Melcher, K., Ng, L.-M., Soon, F.-F., Xu, Y., Suino-Powell, K.M., Kovach, A., Li, J., Yong, E.-L., Xu, H.E.
Deposit date:2010-06-22
Release date:2010-08-25
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.56 Å)
Cite:Identification and mechanism of ABA receptor antagonism.
Nat.Struct.Mol.Biol., 17, 2010
3NMV
  • Download 3nmv
  • View 3nmv
Molmil generated image of 3nmv
CRYSTAL STRUCTURE OF PYRABACTIN-BOUND ABSCISIC ACID RECEPTOR PYL2 MUTANT A93F IN COMPLEX WITH TYPE 2C PROTEIN PHOSPHATASE ABI2
Descriptor:Abscisic acid receptor PYL2, Protein phosphatase 2C 77, 4-bromo-N-(pyridin-2-ylmethyl)naphthalene-1-sulfonamide, ...
Authors:Zhou, X.E., Melcher, K., Ng, L.-M., Soon, F.-F., Xu, Y., Suino-Powell, K.M., Kovach, A., Li, J., Yong, E.-L., Xu, H.E.
Deposit date:2010-06-22
Release date:2010-08-25
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Identification and mechanism of ABA receptor antagonism.
Nat.Struct.Mol.Biol., 17, 2010
3UC3
  • Download 3uc3
  • View 3uc3
Molmil generated image of 3uc3
THE CRYSTAL STRUCTURE OF SNF1-RELATED KINASE 2.3
Descriptor:Serine/threonine-protein kinase SRK2I, COBALT (II) ION
Authors:Zhou, X.E., Ng, L.-M., Soon, F.-F., Kovach, A., Suino-Powell, K.M., Li, J., Melcher, K., Xu, H.E.
Deposit date:2011-10-25
Release date:2011-12-14
Last modified:2012-01-18
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural basis for basal activity and autoactivation of abscisic acid (ABA) signaling SnRK2 kinases.
Proc.Natl.Acad.Sci.USA, 108, 2011
3UC4
  • Download 3uc4
  • View 3uc4
Molmil generated image of 3uc4
THE CRYSTAL STRUCTURE OF SNF1-RELATED KINASE 2.6
Descriptor:Serine/threonine-protein kinase SRK2E
Authors:Zhou, X.E., Ng, L.-M., Soon, F.-F., Kovach, A., Suino-Powell, K.M., Li, J., Melcher, K., Xu, H.E.
Deposit date:2011-10-26
Release date:2011-12-14
Last modified:2012-01-18
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis for basal activity and autoactivation of abscisic acid (ABA) signaling SnRK2 kinases.
Proc.Natl.Acad.Sci.USA, 108, 2011
3UJG
  • Download 3ujg
  • View 3ujg
Molmil generated image of 3ujg
CRYSTAL STRUCTURE OF SNRK2.6 IN COMPLEX WITH HAB1
Descriptor:Serine/threonine-protein kinase SRK2E, Protein phosphatase 2C 16, SULFATE ION, ...
Authors:Zhou, X.E., Soon, F.-F., Ng, L.-M., Kovach, A., Tan, M.H.E., Suino-Powell, K.M., He, Y., Xu, Y., Brunzelle, J.S., Li, J., Melcher, K., Xu, H.E.
Deposit date:2011-11-07
Release date:2012-02-15
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Molecular mimicry regulates ABA signaling by SnRK2 kinases and PP2C phosphatases.
Science, 335, 2012
3UJK
  • Download 3ujk
  • View 3ujk
Molmil generated image of 3ujk
CRYSTAL STRUCTURE OF PROTEIN PHOSPHATASE ABI2
Descriptor:Protein phosphatase 2C 77, MAGNESIUM ION
Authors:Zhou, X.E., Soon, F.-F., Ng, L.-M., Kovach, A., Tan, M.H.E., Suino-Powell, K.M., He, Y., Xu, Y., Brunzelle, J.S., Li, J., Melcher, K., Xu, H.E.
Deposit date:2011-11-07
Release date:2012-02-15
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Molecular mimicry regulates ABA signaling by SnRK2 kinases and PP2C phosphatases.
Science, 335, 2012
3UJL
  • Download 3ujl
  • View 3ujl
Molmil generated image of 3ujl
CRYSTAL STRUCTURE OF ABSCISIC ACID BOUND PYL2 IN COMPLEX WITH TYPE 2C PROTEIN PHOSPHATASE ABI2
Descriptor:Abscisic acid receptor PYL2, Protein phosphatase 2C 77, (2Z,4E)-5-[(1S)-1-hydroxy-2,6,6-trimethyl-4-oxocyclohex-2-en-1-yl]-3-methylpenta-2,4-dienoic acid, ...
Authors:Zhou, X.E., Soon, F.-F., Ng, L.-M., Kovach, A., Tan, M.H.E., Suino-Powell, K.M., He, Y., Xu, Y., Brunzelle, J.S., Li, J., Melcher, K., Xu, H.E.
Deposit date:2011-11-07
Release date:2012-02-15
Last modified:2012-03-28
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Molecular mimicry regulates ABA signaling by SnRK2 kinases and PP2C phosphatases.
Science, 335, 2012
3UP0
  • Download 3up0
  • View 3up0
Molmil generated image of 3up0
NUCLEAR RECEPTOR DAF-12 FROM HOOKWORM ANCYLOSTOMA CEYLANICUM IN COMPLEX WITH (25S)-DELTA7-DAFACHRONIC ACID
Descriptor:aceDAF-12, Nuclear receptor coactivator 2, (5beta,14beta,17alpha,25S)-3-oxocholest-7-en-26-oic acid
Authors:Zhi, X., Zhou, X.E., Melcher, K., Motola, D.L., Gelmedin, V., Hawdon, J., Kliewer, S.A., Mangelsdorf, D.J., Xu, H.E.
Deposit date:2011-11-17
Release date:2011-12-14
Last modified:2012-02-29
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural Conservation of Ligand Binding Reveals a Bile Acid-like Signaling Pathway in Nematodes.
J.Biol.Chem., 287, 2012
3UP3
  • Download 3up3
  • View 3up3
Molmil generated image of 3up3
NUCLEAR RECEPTOR DAF-12 FROM HOOKWORM ANCYLOSTOMA CEYLANICUM IN COMPLEX WITH (25S)-CHOLESTENOIC ACID
Descriptor:aceDAF-12, Nuclear receptor coactivator 2, (8alpha,10alpha,25S)-3-hydroxycholesta-3,5-dien-26-oic acid, ...
Authors:Zhi, X., Zhou, X.E., Melcher, K., Motola, D.L., Gelmedin, V., Hawdon, J., Kliewer, S.A., Mangelsdorf, D.J., Xu, H.E.
Deposit date:2011-11-17
Release date:2011-12-14
Last modified:2012-02-29
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Structural Conservation of Ligand Binding Reveals a Bile Acid-like Signaling Pathway in Nematodes.
J.Biol.Chem., 287, 2012
4IAQ
  • Download 4iaq
  • View 4iaq
Molmil generated image of 4iaq
CRYSTAL STRUCTURE OF THE CHIMERIC PROTEIN OF 5-HT1B-BRIL IN COMPLEX WITH DIHYDROERGOTAMINE (PSI COMMUNITY TARGET)
Descriptor:Chimera protein of human 5-hydroxytryptamine receptor 1B and E. Coli soluble cytochrome b562, Dihydroergotamine
Authors:Wang, C., Jiang, Y., Ma, J., Wu, H., Wacker, D., Katritch, V., Han, G.W., Liu, W., Huang, X., Vardy, E., McCorvy, J.D., Gao, X., Zhou, E.X., Melcher, K., Zhang, C., Bai, F., Yang, H., Yang, L., Jiang, H., Roth, B.L., Cherezov, V., Stevens, R.C., Xu, H.E., GPCR Network (GPCR)
Deposit date:2012-12-07
Release date:2013-03-13
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis for molecular recognition at serotonin receptors.
Science, 340, 2013
4IAR
  • Download 4iar
  • View 4iar
Molmil generated image of 4iar
CRYSTAL STRUCTURE OF THE CHIMERIC PROTEIN OF 5-HT1B-BRIL IN COMPLEX WITH ERGOTAMINE (PSI COMMUNITY TARGET)
Descriptor:Chimera protein of human 5-hydroxytryptamine receptor 1B and E. Coli soluble cytochrome b562, Ergotamine, (2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate
Authors:Wang, C., Jiang, Y., Ma, J., Wu, H., Wacker, D., Katritch, V., Han, G.W., Liu, W., Huang, X., Vardy, E., McCorvy, J.D., Gao, X., Zhou, E.X., Melcher, K., Zhang, C., Bai, F., Yang, H., Yang, L., Jiang, H., Roth, B.L., Cherezov, V., Stevens, R.C., Xu, H.E., GPCR Network (GPCR)
Deposit date:2012-12-07
Release date:2013-03-13
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural basis for molecular recognition at serotonin receptors.
Science, 340, 2013
4IH1
  • Download 4ih1
  • View 4ih1
Molmil generated image of 4ih1
CRYSTAL STRUCTURE OF KARRIKIN INSENSITIVE 2 (KAI2) FROM ARABIDOPSIS THALIANA
Descriptor:Hydrolase, alpha/beta fold family protein
Authors:Zhou, X.E., Zhao, L.-H., Wu, Z.-S., Yi, W., Li, S., Li, Y., Xu, Y., Xu, T.-H., Liu, Y., Chen, R.-Z., Kovach, A., Kang, Y., Hou, L., He, Y., Zhang, C., Melcher, K., Xu, H.E.
Deposit date:2012-12-18
Release date:2013-01-30
Last modified:2013-10-23
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Crystal structures of two phytohormone signal-transducing alpha / beta hydrolases: karrikin-signaling KAI2 and strigolactone-signaling DWARF14.
Cell Res., 23, 2013
4IH4
  • Download 4ih4
  • View 4ih4
Molmil generated image of 4ih4
CRYSTAL STRUCTURE OF ARABIDOPSIS DWARF14 ORTHOLOGUE, ATD14
Descriptor:AT3g03990/T11I18_10
Authors:Zhou, X.E., Zhao, L.-H., Wu, Z.-S., Yi, W., Li, S., Li, Y., Xu, Y., Xu, T.-H., Liu, Y., Chen, R.-Z., Kovach, A., Kang, Y., Hou, L., He, Y., Zhang, C., Melcher, K., Xu, H.E.
Deposit date:2012-12-18
Release date:2013-01-30
Last modified:2013-10-23
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Crystal structures of two phytohormone signal-transducing alpha / beta hydrolases: karrikin-signaling KAI2 and strigolactone-signaling DWARF14.
Cell Res., 23, 2013
4IH9
  • Download 4ih9
  • View 4ih9
Molmil generated image of 4ih9
CRYSTAL STRUCTURE OF RICE DWARF14 (D14)
Descriptor:Dwarf 88 esterase
Authors:Zhou, X.E., Zhao, L.-H., Wu, Z.-S., Yi, W., Li, S., Li, Y., Xu, Y., Xu, T.-H., Liu, Y., Chen, R.-Z., Kovach, A., Kang, Y., Hou, L., He, Y., Zhang, C., Melcher, K., Xu, H.E.
Deposit date:2012-12-18
Release date:2013-01-30
Last modified:2013-10-23
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Crystal structures of two phytohormone signal-transducing alpha / beta hydrolases: karrikin-signaling KAI2 and strigolactone-signaling DWARF14.
Cell Res., 23, 2013
4IHA
  • Download 4iha
  • View 4iha
Molmil generated image of 4iha
CRYSTAL STRUCTURE OF RICE DWARF14 (D14) IN COMPLEX WITH A GR24 HYDROLYSIS INTERMEDIATE
Descriptor:Dwarf 88 esterase, (2R,3R)-2,4,4-trihydroxy-3-methylbutanal
Authors:Zhou, X.E., Zhao, L.-H., Wu, Z.-S., Yi, W., Li, S., Li, Y., Xu, Y., Xu, T.-H., Liu, Y., Chen, R.-Z., Kovach, A., Kang, Y., Hou, L., He, Y., Zhang, C., Melcher, K., Xu, H.E.
Deposit date:2012-12-18
Release date:2013-01-23
Last modified:2013-10-23
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Crystal structures of two phytohormone signal-transducing alpha / beta hydrolases: karrikin-signaling KAI2 and strigolactone-signaling DWARF14.
Cell Res., 23, 2013
4IUA
  • Download 4iua
  • View 4iua
Molmil generated image of 4iua
CRYSTAL STRUCTURE OF THE NK2 FRAGMENT (31-290) OF THE MOUSE HEPATOCYTE GROWTH FACTOR/SCATTER FACTOR
Descriptor:Hepatocyte growth factor, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, SULFATE ION
Authors:Tolbert, W.D., Zhou, E., Kovach, A., Melcher, K., Xu, H.E.
Deposit date:2013-01-20
Release date:2013-02-13
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Crystal Structure of the NK2 Fragment of the mouse Hepatocyte Growth Factor/Scatter Factor
To be Published