Author results

2K21
  • Download 2k21
  • View 2k21
Molmil generated image of 2k21
NMR STRUCTURE OF HUMAN KCNE1 IN LMPG MICELLES AT PH 6.0 AND 40 DEGREE C
Descriptor:Potassium voltage-gated channel subfamily E member
Authors:Kang, C., Tian, C., Sonnichsen, F.D., Smith, J.A., Meiler, J., George, A.L., Vanoye, C.G., Sanders, C.R., Kim, H.
Deposit date:2008-03-19
Release date:2008-12-09
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure of KCNE1 and implications for how it modulates the KCNQ1 potassium channel.
Biochemistry, 47, 2008
2K39
  • Download 2k39
  • View 2k39
Molmil generated image of 2k39
RECOGNITION DYNAMICS UP TO MICROSECONDS REVEALED FROM RDC DERIVED UBIQUITIN ENSEMBLE IN SOLUTION
Descriptor:Ubiquitin
Authors:Lange, O.F., Lakomek, N.A., Fares, C., Schroder, G., Walter, K., Becker, S., Meiler, J., Grubmuller, H., Griesinger, C., de Groot, B.L.
Deposit date:2008-04-25
Release date:2008-06-24
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Recognition dynamics up to microseconds revealed from an RDC-derived ubiquitin ensemble in solution.
Science, 320, 2008
2KN5
  • Download 2kn5
  • View 2kn5
Molmil generated image of 2kn5
A CORRESPONDENCE BETWEEN SOLUTION-STATE DYNAMICS OF AN INDIVIDUAL PROTEIN AND THE SEQUENCE AND CONFORMATIONAL DIVERSITY OF ITS FAMILY
Descriptor:Ubiquitin
Authors:Friedland, G.D.
Deposit date:2009-08-14
Release date:2009-11-17
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:A correspondence between solution-state dynamics of an individual protein and the sequence and conformational diversity of its family.
PLOS COMPUT.BIOL., 5, 2009
3MF6
  • Download 3mf6
  • View 3mf6
Molmil generated image of 3mf6
COMPUTATIONALLY DESIGNED ENDO-1,4-BETA-XYLANASE
Descriptor:Endo-1,4-beta-xylanase, SULFATE ION
Authors:Morin, A., Harp, J.M.
Deposit date:2010-04-01
Release date:2010-11-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.28 Å)
Cite:Computational design of an endo-1,4-{beta}-xylanase ligand binding site.
Protein Eng.Des.Sel., 24, 2011
3MF9
  • Download 3mf9
  • View 3mf9
Molmil generated image of 3mf9
COMPUTATIONALLY DESIGNED ENDO-1,4-BETA-XYLANASE
Descriptor:Endo-1,4-beta-xylanase, SULFATE ION
Authors:Morin, A., Harp, J.M.
Deposit date:2010-04-01
Release date:2010-11-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Computational design of an endo-1,4-{beta}-xylanase ligand binding site.
Protein Eng.Des.Sel., 24, 2011
3MFA
  • Download 3mfa
  • View 3mfa
Molmil generated image of 3mfa
COMPUTATIONALLY DESIGNED ENDO-1,4-BETA-XYLANASE
Descriptor:Endo-1,4-beta-xylanase, SULFATE ION
Authors:Morin, A., Harp, J.M.
Deposit date:2010-04-01
Release date:2010-11-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:Computational design of an endo-1,4-{beta}-xylanase ligand binding site.
Protein Eng.Des.Sel., 24, 2011
3MFC
  • Download 3mfc
  • View 3mfc
Molmil generated image of 3mfc
COMPUTATIONALLY DESIGNED END0-1,4-BETA,XYLANASE
Descriptor:Endo-1,4-beta-xylanase, SULFATE ION
Authors:Morin, A., Harp, J.M.
Deposit date:2010-04-01
Release date:2010-11-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Computational design of an endo-1,4-{beta}-xylanase ligand binding site.
Protein Eng.Des.Sel., 24, 2011
3TDM
  • Download 3tdm
  • View 3tdm
Molmil generated image of 3tdm
COMPUTATIONALLY DESIGNED TIM-BARREL PROTEIN, HALFFLR
Descriptor:Computationally designed two-fold symmetric TIM-barrel protein, FLR (half molecule), PHOSPHATE ION
Authors:Harp, J.M., Fortenberry, C., Bowman, E., Profitt, W., Dorr, B., Mizoue, L.
Deposit date:2011-08-11
Release date:2011-11-16
Last modified:2011-11-23
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Exploring symmetry as an avenue to the computational design of large protein domains.
J.Am.Chem.Soc., 133, 2011
3TDN
  • Download 3tdn
  • View 3tdn
Molmil generated image of 3tdn
COMPUTATIONALLY DESIGNED TWO-FOLD SYMMETRIC TIM-BARREL PROTEIN, FLR
Descriptor:FLR SYMMETRIC ALPHA-BETA TIM BARREL
Authors:Harp, J.M., Fortenberry, C., Bowman, E., Profitt, W., Dorr, B., Mizoue, L., Meiler, J.
Deposit date:2011-08-11
Release date:2011-11-16
Last modified:2011-11-23
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Exploring symmetry as an avenue to the computational design of large protein domains.
J.Am.Chem.Soc., 133, 2011
2LLE
  • Download 2lle
  • View 2lle
Molmil generated image of 2lle
COMPUTATIONAL DESIGN OF AN EIGHT-STRANDED (BETA/ALPHA)-BARREL FROM FRAGMENTS OF DIFFERENT FOLDS
Descriptor:Chemotaxis protein CheY, Imidazole glycerol phosphate synthase subunit HisF chimera
Authors:Coles, M., Truffault, V., Eisenbeis, S., Proffitt, W., Meiler, J., Hocker, B.
Deposit date:2011-11-07
Release date:2012-03-21
Method:SOLUTION NMR
Cite:Potential of fragment recombination for rational design of proteins.
J.Am.Chem.Soc., 134, 2012
4GSD
  • Download 4gsd
  • View 4gsd
Molmil generated image of 4gsd
H5.3 FAB STRUCTURE
Descriptor:H5.3 Fab Light Chain, H5.3 Fab Heavy Chain
Authors:Spiller, B.W., Winarski, K.L.
Deposit date:2012-08-27
Release date:2013-08-21
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.251 Å)
Cite:Human antibodies that neutralize respiratory droplet transmissible H5N1 influenza viruses.
J.Clin.Invest., 123, 2013
4HFW
  • Download 4hfw
  • View 4hfw
Molmil generated image of 4hfw
ANTI ROTAVIRUS ANTIBODY
Descriptor:6-26 Fab Light chain, 6-26 Fab Heavy chain, SULFATE ION
Authors:Spiller, B.W., Aiyegbo, M., Crowe, J.E.
Deposit date:2012-10-05
Release date:2013-05-29
Method:X-RAY DIFFRACTION (2.601 Å)
Cite:Human Rotavirus VP6-Specific Antibodies Mediate Intracellular Neutralization by Binding to a Quaternary Structure in the Transcriptional Pore.
Plos One, 8, 2013
4OR2
  • Download 4or2
  • View 4or2
Molmil generated image of 4or2
HUMAN CLASS C G PROTEIN-COUPLED METABOTROPIC GLUTAMATE RECEPTOR 1 IN COMPLEX WITH A NEGATIVE ALLOSTERIC MODULATOR
Descriptor:Soluble cytochrome b562, Metabotropic glutamate receptor 1, 4-fluoro-N-methyl-N-{4-[6-(propan-2-ylamino)pyrimidin-4-yl]-1,3-thiazol-2-yl}benzamide, ...
Authors:Wu, H., Wang, C., Gregory, K.J., Han, G.W., Cho, H.P., Xia, Y., Niswender, C.M., Katritch, V., Cherezov, V., Conn, P.J., Stevens, R.C., GPCR Network (GPCR)
Deposit date:2014-02-10
Release date:2014-03-19
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of a class C GPCR metabotropic glutamate receptor 1 bound to an allosteric modulator
Science, 344, 2014
4PAM
  • Download 4pam
  • View 4pam
Molmil generated image of 4pam
A CONSERVED PHENYLALANINE AS RELAY BETWEEN THE 5 HELIX AND THE GDP BINDING REGION OF HETEROTRIMERIC G PROTEIN
Descriptor:Guanine nucleotide-binding protein G(i) subunit alpha-1, GUANOSINE-5'-DIPHOSPHATE, SULFITE ION, ...
Authors:Kaya, A.I., Lokits, A.D., Gilbert, J., Iverson, T.M., Meiler, J., Hamm, H.E.
Deposit date:2014-04-09
Release date:2014-07-30
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.101 Å)
Cite:A Conserved Phenylalanine as a Relay between the alpha 5 Helix and the GDP Binding Region of Heterotrimeric Gi Protein alpha Subunit.
J.Biol.Chem., 289, 2014
4PAN
  • Download 4pan
  • View 4pan
Molmil generated image of 4pan
A CONSERVED PHENYLALANINE AS RELAY BETWEEN THE 5 HELIX AND THE GDP BINDING REGION OF HETEROTRIMERIC G PROTEIN
Descriptor:Guanine nucleotide-binding protein G(i) subunit alpha-1, GUANOSINE-5'-DIPHOSPHATE, SULFITE ION, ...
Authors:Kaya, A.I., Lokits, A.D., Gilbert, J., Iverson, T.M., Meiler, J., Hamm, H.E.
Deposit date:2014-04-09
Release date:2014-07-30
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:A Conserved Phenylalanine as a Relay between the alpha 5 Helix and the GDP Binding Region of Heterotrimeric Gi Protein alpha Subunit.
J.Biol.Chem., 289, 2014
4PAO
  • Download 4pao
  • View 4pao
Molmil generated image of 4pao
A CONSERVED PHENYLALANINE AS RELAY BETWEEN THE 5 HELIX AND THE GDP BINDING REGION OF HETEROTRIMERIC G PROTEIN
Descriptor:Guanine nucleotide-binding protein G(i) subunit alpha-1, 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, MAGNESIUM ION
Authors:Kaya, A.I., Lokits, A.D., Gilbert, J., Iverson, T.M., Meiler, J., Hamm, H.E.
Deposit date:2014-04-09
Release date:2014-07-30
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.003 Å)
Cite:A Conserved Phenylalanine as a Relay between the alpha 5 Helix and the GDP Binding Region of Heterotrimeric Gi Protein alpha Subunit.
J.Biol.Chem., 289, 2014
4PAQ
  • Download 4paq
  • View 4paq
Molmil generated image of 4paq
A CONSERVED PHENYLALANINE AS RELAY BETWEEN THE 5 HELIX AND THE GDP BINDING REGION OF HETEROTRIMERIC G PROTEIN
Descriptor:Guanine nucleotide-binding protein G(i) subunit alpha-1, 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, MAGNESIUM ION
Authors:Kaya, A.I., Lokits, A.D., Gilbert, J., Iverson, T.M., Meiler, J., Hamm, H.E.
Deposit date:2014-04-09
Release date:2014-07-30
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2 Å)
Cite:A Conserved Phenylalanine as a Relay between the alpha 5 Helix and the GDP Binding Region of Heterotrimeric Gi Protein alpha Subunit.
J.Biol.Chem., 289, 2014
4YAQ
  • Download 4yaq
  • View 4yaq
Molmil generated image of 4yaq
CRYSTAL STRUCTURE OF A COMPUTATIONALLY OPTIMIZED PG9 MUTANT
Descriptor:PG9_N100FY Fab heavy chain, PG9_N100FY Light Chain, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ...
Authors:Murrell, S., Julien, J.P., Wilson, I.A.
Deposit date:2015-02-17
Release date:2015-06-03
Last modified:2017-08-23
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Redesigned HIV antibodies exhibit enhanced neutralizing potency and breadth.
J.Clin.Invest., 125, 2015
4ZV6
  • Download 4zv6
  • View 4zv6
Molmil generated image of 4zv6
CRYSTAL STRUCTURE OF THE ARTIFICIAL ALPHAREP-7 OCTARELLINV.1 COMPLEX
Descriptor:AlphaRep-7, Octarellin V.1
Authors:Figueroa, M., Sleutel, M., Urvoas, A., Valerio-Lepiniec, M., Minard, P., Martial, J.A., van de Weerdt, C.
Deposit date:2015-05-18
Release date:2016-05-25
Last modified:2016-06-08
Method:X-RAY DIFFRACTION (2.22 Å)
Cite:The unexpected structure of the designed protein Octarellin V.1 forms a challenge for protein structure prediction tools.
J.Struct.Biol., 195, 2016
4ZWQ
  • Download 4zwq
  • View 4zwq
Molmil generated image of 4zwq
CRYSTAL STRUCTURE OF THE BACTERIOPHAGE T4 RECOMBINATION MEDIATOR PROTEIN UVSY, LATTICE TYPE I
Descriptor:Recombination protein uvsY
Authors:Gajewski, S., White, S.W.
Deposit date:2015-05-19
Release date:2016-03-02
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (2.351 Å)
Cite:Structure and mechanism of the phage T4 recombination mediator protein UvsY.
Proc.Natl.Acad.Sci.USA, 113, 2016
4ZWR
  • Download 4zwr
  • View 4zwr
Molmil generated image of 4zwr
CRYSTAL STRUCTURE OF THE BACTERIOPHAGE T4 RECOMBINATION MEDIATOR PROTEIN UVSY, LATTICE TYPE II
Descriptor:Recombination protein uvsY
Authors:Gajewski, S., White, S.W.
Deposit date:2015-05-19
Release date:2016-03-02
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (3.3857 Å)
Cite:Structure and mechanism of the phage T4 recombination mediator protein UvsY.
Proc.Natl.Acad.Sci.USA, 113, 2016
4ZWS
  • Download 4zws
  • View 4zws
Molmil generated image of 4zws
CRYSTAL STRUCTURE OF THE BACTERIOPHAGE T4 RECOMBINATION MEDIATOR PROTEIN UVSY, LATTICE TYPE III
Descriptor:Recombination protein uvsY
Authors:Gajewski, S., White, S.W.
Deposit date:2015-05-19
Release date:2016-03-02
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure and mechanism of the phage T4 recombination mediator protein UvsY.
Proc.Natl.Acad.Sci.USA, 113, 2016
4ZWT
  • Download 4zwt
  • View 4zwt
Molmil generated image of 4zwt
CRYSTAL STRUCTURE OF THE BACTERIOPHAGE T4 RECOMBINATION MEDIATOR PROTEIN UVSY, LATTICE TYPE IV
Descriptor:Recombination protein uvsY
Authors:Gajewski, S., White, S.W.
Deposit date:2015-05-19
Release date:2016-03-02
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (4.2 Å)
Cite:Structure and mechanism of the phage T4 recombination mediator protein UvsY.
Proc.Natl.Acad.Sci.USA, 113, 2016
5BOP
  • Download 5bop
  • View 5bop
Molmil generated image of 5bop
CRYSTAL STRUCTURE OF THE ARTIFICIAL NANOBODY OCTARELLINV.1 COMPLEX
Descriptor:Nanobody, Octarellin V.1
Authors:Figueroa, M., Sleutel, M., Pardon, E., Steyaert, J., Martial, J.A., van de Weerdt, C.
Deposit date:2015-05-27
Release date:2016-05-25
Last modified:2016-06-08
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:The unexpected structure of the designed protein Octarellin V.1 forms a challenge for protein structure prediction tools.
J.Struct.Biol., 195, 2016
5ITB
  • Download 5itb
  • View 5itb
Molmil generated image of 5itb
CRYSTAL STRUCTURE OF THE ANTI-RSV F FAB 14N4
Descriptor:anti-RSV F Fab 14N4 Heavy chain, anti-RSV F Fab 14N4 Light chain
Authors:Mousa, J.J., Crowe, J.E.
Deposit date:2016-03-16
Release date:2016-10-26
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for nonneutralizing antibody competition at antigenic site II of the respiratory syncytial virus fusion protein.
Proc.Natl.Acad.Sci.USA, 113, 2016
<12>