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3HCO
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BU of 3hco by Molmil
Human ferrochelatase with Cd and protoporphyrin IX bound
Descriptor: BICARBONATE ION, CHOLIC ACID, FE2/S2 (INORGANIC) CLUSTER, ...
Authors:Medlock, A.E, Dailey, H.A, Lanzilotta, W.N.
Deposit date:2009-05-06
Release date:2009-11-10
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Product release rather than chelation determines metal specificity for ferrochelatase.
J.Mol.Biol., 393, 2009
3HCR
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BU of 3hcr by Molmil
Human Ferrochelatase with deuteroporphyrin and Ni Bound
Descriptor: CHLORIDE ION, CHOLIC ACID, FE(III) DEUTEROPORPHYRIN IX, ...
Authors:Medlock, A.E, Dailey, H.A, Lanzilotta, W.N.
Deposit date:2009-05-06
Release date:2009-11-10
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Product release rather than chelation determines metal specificity for ferrochelatase.
J.Mol.Biol., 393, 2009
3HCN
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BU of 3hcn by Molmil
Hg and protoporphyrin bound Human Ferrochelatase
Descriptor: BICARBONATE ION, CHOLIC ACID, FE2/S2 (INORGANIC) CLUSTER, ...
Authors:Medlock, A.E, Dailey, H.A, Lanzilotta, W.N.
Deposit date:2009-05-06
Release date:2009-11-10
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Product release rather than chelation determines metal specificity for ferrochelatase.
J.Mol.Biol., 393, 2009
3HCP
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BU of 3hcp by Molmil
Human ferrochelatase with Mn and deuteroporphyrin bound
Descriptor: CHOLIC ACID, FE(III) DEUTEROPORPHYRIN IX, FE2/S2 (INORGANIC) CLUSTER, ...
Authors:Medlock, A.E, Dailey, H.A, Lanzilotta, W.N.
Deposit date:2009-05-06
Release date:2009-11-10
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2 Å)
Cite:Product release rather than chelation determines metal specificity for ferrochelatase.
J.Mol.Biol., 393, 2009
2QD3
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BU of 2qd3 by Molmil
Wild type human ferrochelatase crystallized with ammonium sulfate
Descriptor: CHOLIC ACID, FE2/S2 (INORGANIC) CLUSTER, Ferrochelatase, ...
Authors:Medlock, A.E, Dailey, T.A, Ross, T.A, Dailey, H.A, Lanzilotta, W.N.
Deposit date:2007-06-20
Release date:2007-10-30
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:A pi-Helix Switch Selective for Porphyrin Deprotonation and Product Release in Human Ferrochelatase.
J.Mol.Biol., 373, 2007
2QD2
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BU of 2qd2 by Molmil
F110A variant of human ferrochelatase with protoheme bound
Descriptor: BICARBONATE ION, CHOLIC ACID, FE2/S2 (INORGANIC) CLUSTER, ...
Authors:Medlock, A.E, Dailey, T.A, Ross, T.A, Dailey, H.A, Lanzilota, W.N.
Deposit date:2007-06-20
Release date:2007-10-30
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:A pi-Helix Switch Selective for Porphyrin Deprotonation and Product Release in Human Ferrochelatase.
J.Mol.Biol., 373, 2007
2QD1
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BU of 2qd1 by Molmil
2.2 Angstrom Structure of the human ferrochelatase variant E343K with substrate bound
Descriptor: CHOLIC ACID, FE2/S2 (INORGANIC) CLUSTER, Ferrochelatase, ...
Authors:Medlock, A.E, Dailey, T.A, Ross, T.A, Dailey, H.A, Lanzilotta, W.N.
Deposit date:2007-06-20
Release date:2007-10-30
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:A pi-Helix Switch Selective for Porphyrin Deprotonation and Product Release in Human Ferrochelatase.
J.Mol.Biol., 373, 2007
2QD4
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BU of 2qd4 by Molmil
Wild type human ferrochelatase crystallized with MnCl2
Descriptor: CHLORIDE ION, CHOLIC ACID, FE2/S2 (INORGANIC) CLUSTER, ...
Authors:Medlock, A.E, Dailey, T.A, Ross, T.A, Dailey, H.A, Lanzilotta, W.N.
Deposit date:2007-06-20
Release date:2007-10-30
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2 Å)
Cite:A pi-Helix Switch Selective for Porphyrin Deprotonation and Product Release in Human Ferrochelatase.
J.Mol.Biol., 373, 2007
7L78
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BU of 7l78 by Molmil
H235C variant of Yeast Ferrochelatase
Descriptor: CHOLIC ACID, Ferrochelatase, mitochondrial
Authors:Lanzilotta, W.N, Medlock, A.E.
Deposit date:2020-12-27
Release date:2021-11-24
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Mitochondrial contact site and cristae organizing system (MICOS) machinery supports heme biosynthesis by enabling optimal performance of ferrochelatase.
Redox Biol, 46, 2021
3AQI
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BU of 3aqi by Molmil
H240A variant of human ferrochelatase
Descriptor: CHOLIC ACID, FE2/S2 (INORGANIC) CLUSTER, Ferrochelatase, ...
Authors:Lanzilotta, W.N, Medlock, A.E, Dailey, T.A, Dailey, H.A.
Deposit date:2010-11-03
Release date:2012-01-25
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:H240A variant of human ferrochelatase
To be published
2PNJ
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BU of 2pnj by Molmil
Crystal structure of human ferrochelatase mutant with Phe 337 replaced by Ala
Descriptor: CHOLIC ACID, FE2/S2 (INORGANIC) CLUSTER, Ferrochelatase, ...
Authors:Dailey, H.A, Wu, C.-K, Horanyi, P, Medlock, A.E, Najahi-Missaoui, W, Burden, A.E, Dailey, T.A, Rose, J.P.
Deposit date:2007-04-24
Release date:2007-10-02
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Altered orientation of active site residues in variants of human ferrochelatase. Evidence for a hydrogen bond network involved in catalysis
Biochemistry, 46, 2007
2PO5
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BU of 2po5 by Molmil
Crystal structure of human ferrochelatase mutant with His 263 replaced by Cys
Descriptor: CHOLIC ACID, FE2/S2 (INORGANIC) CLUSTER, Ferrochelatase, ...
Authors:Dailey, H.A, Wu, C.-K, Horanyi, P, Medlock, A.E, Najahi-Missaoui, A.E.W, Burden, A, Dailey, T.A, Rose, J.P.
Deposit date:2007-04-25
Release date:2007-10-02
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Altered orientation of active site residues in variants of human ferrochelatase. Evidence for a hydrogen bond network involved in catalysis
Biochemistry, 46, 2007
2PO7
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BU of 2po7 by Molmil
Crystal structure of human ferrochelatase mutant with His 341 replaced by Cys
Descriptor: CHOLIC ACID, FE2/S2 (INORGANIC) CLUSTER, Ferrochelatase, ...
Authors:Dailey, H.A, Wu, C.-K, Horanyi, P, Medlock, A.E, Najahi-Missaoui, W, Burden, A, Dailey, T.A, Rose, J.P.
Deposit date:2007-04-25
Release date:2007-10-02
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Altered orientation of active site residues in variants of human ferrochelatase. Evidence for a hydrogen bond network involved in catalysis.
Biochemistry, 46, 2007
4F4D
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BU of 4f4d by Molmil
F337R variant of human ferrochelatase
Descriptor: CHLORIDE ION, CHOLIC ACID, FE2/S2 (INORGANIC) CLUSTER, ...
Authors:Lanzilotta, W.N, Medlock, A.E, Dailey, T.E, Dailey, H.A.
Deposit date:2012-05-10
Release date:2012-09-12
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:F337R Variant of Human Ferrochelatase
TO BE PUBLISHED
4KLR
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BU of 4klr by Molmil
E343Q variant of human ferrochelatase
Descriptor: BICARBONATE ION, CHLORIDE ION, CHOLIC ACID, ...
Authors:Lanzilotta, W.N, Medlock, A.E.
Deposit date:2013-05-07
Release date:2014-06-18
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:E343Q variant of human ferrochelatase
To be Published
4KMM
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BU of 4kmm by Molmil
M76H variant of human ferrochelatase
Descriptor: CHLORIDE ION, CHOLIC ACID, FE2/S2 (INORGANIC) CLUSTER, ...
Authors:Lanzilotta, W.N, Medlock, A.E.
Deposit date:2013-05-08
Release date:2014-05-14
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:M76H variant of human ferrochelatase
To be Published
4KLA
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BU of 4kla by Molmil
E343D variant of human ferrochelatase
Descriptor: CHOLIC ACID, FE2/S2 (INORGANIC) CLUSTER, Ferrochelatase, ...
Authors:Lanzilotta, W.N, Medlock, A.E.
Deposit date:2013-05-07
Release date:2014-05-07
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:E343D variant of human ferrochelatase
To be Published
4KLC
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BU of 4klc by Molmil
E343D/F110A Double mutant of human ferrochelatase
Descriptor: FE2/S2 (INORGANIC) CLUSTER, Ferrochelatase, mitochondrial, ...
Authors:Lanzilotta, W.N, Medlock, A.E.
Deposit date:2013-05-07
Release date:2014-06-18
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:E343D/F110A Double mutant of human ferrochelatase
To be Published
4MK4
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BU of 4mk4 by Molmil
S197C variant of human ferrochelatase.
Descriptor: CHOLIC ACID, FE2/S2 (INORGANIC) CLUSTER, Ferrochelatase, ...
Authors:Lanzilotta, W.N, Medlock, A.E, Dailey, T.E, Dailey, H.A.
Deposit date:2013-09-04
Release date:2013-09-25
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:S197C variant of human ferrochelatase.
To be Published
2QD5
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BU of 2qd5 by Molmil
Structure of wild type human ferrochelatase in complex with a lead-porphyrin compound
Descriptor: ACETIC ACID, CHOLIC ACID, FE2/S2 (INORGANIC) CLUSTER, ...
Authors:Meldock, A.E, Dailey, T.A, Ross, T.A, Dailey, H.A, Lanzilotta, W.N.
Deposit date:2007-06-20
Release date:2007-10-30
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:A pi-Helix Switch Selective for Porphyrin Deprotonation and Product Release in Human Ferrochelatase.
J.Mol.Biol., 373, 2007

217705

PDB entries from 2024-03-27

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