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6R4O
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BU of 6r4o by Molmil
Structure of a truncated adenylyl cyclase bound to MANT-GTP, forskolin and an activated stimulatory Galphas protein
Descriptor: 3'-O-(N-METHYLANTHRANILOYL)-GUANOSINE-5'-TRIPHOSPHATE, 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, Adenylate cyclase 9, ...
Authors:Qi, C, Sorrentino, S, Medalia, O, Korkhov, V.M.
Deposit date:2019-03-22
Release date:2019-05-08
Last modified:2019-11-06
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:The structure of a membrane adenylyl cyclase bound to an activated stimulatory G protein.
Science, 364, 2019
6EQC
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BU of 6eqc by Molmil
Cryo-EM reconstruction of a complex of a binding protein and human adenovirus C5 hexon
Descriptor: Hexon protein, scFv of 9C12 antibody
Authors:Schmid, M, Ernst, P, Honegger, A, Suomalainen, M, Zimmermann, M, Braun, L, Stauffer, S, Thom, C, Dreier, B, Eibauer, M, Kipar, A, Vogel, V, Greber, U.F, Medalia, O, Plueckthun, A.
Deposit date:2017-10-12
Release date:2018-02-07
Last modified:2018-02-14
Method:ELECTRON MICROSCOPY (7.4 Å)
Cite:Adenoviral vector with shield and adapter increases tumor specificity and escapes liver and immune control.
Nat Commun, 9, 2018
6FUY
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BU of 6fuy by Molmil
Crystal structure of human full-length vinculin-T12-A974K (residues 1-1066)
Descriptor: CALCIUM ION, Vinculin
Authors:Chorev, D.S, Volberg, T, Livne, A, Eisenstein, M, Martins, B, Kam, Z, Jockusch, B.M, Medalia, O, Sharon, M, Geiger, B.
Deposit date:2018-02-28
Release date:2018-03-14
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3 Å)
Cite:Conformational states during vinculin unlocking differentially regulate focal adhesion properties.
Sci Rep, 8, 2018
7PER
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BU of 7per by Molmil
Model of the inner ring of the human nuclear pore complex
Descriptor: Nuclear pore complex protein Nup155, Nuclear pore complex protein Nup205, Nuclear pore complex protein Nup93, ...
Authors:Schuller, A.P, Wojtynek, M, Mankus, D, Tatli, M, Kronenberg-Tenga, R, Regmi, S.G, Dasso, M, Weis, K, Medalia, O, Schwartz, T.U.
Deposit date:2021-08-11
Release date:2021-10-20
Last modified:2021-11-24
Method:ELECTRON MICROSCOPY (35 Å)
Cite:The cellular environment shapes the nuclear pore complex architecture.
Nature, 598, 2021
7PEQ
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BU of 7peq by Molmil
Model of the outer rings of the human nuclear pore complex
Descriptor: Nuclear pore complex protein Nup107, Nuclear pore complex protein Nup133, Nuclear pore complex protein Nup160, ...
Authors:Schuller, A.P, Wojtynek, M, Mankus, D, Tatli, M, Kronenberg-Tenga, R, Regmi, S.G, Dasso, M, Weis, K, Medalia, O, Schwartz, T.U.
Deposit date:2021-08-11
Release date:2021-10-20
Last modified:2021-11-24
Method:ELECTRON MICROSCOPY (35 Å)
Cite:The cellular environment shapes the nuclear pore complex architecture.
Nature, 598, 2021
7P00
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BU of 7p00 by Molmil
Human Neurokinin 1 receptor (NK1R) substance P Gq chimera (mGsqi) complex
Descriptor: Antibody fragment scFv16, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Thom, C, Ehrenmann, J, Vacca, S, Waltenspuhl, Y, Schoppe, J, Medalia, O, Pluckthun, A.
Deposit date:2021-06-29
Release date:2021-12-15
Method:ELECTRON MICROSCOPY (2.71 Å)
Cite:Structures of neurokinin 1 receptor in complex with G q and G s proteins reveal substance P binding mode and unique activation features.
Sci Adv, 7, 2021
7P02
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BU of 7p02 by Molmil
Human Neurokinin 1 receptor (NK1R) substance P Gs complex
Descriptor: Antibody fragment scFv16, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Thom, C, Ehrenmann, J, Vacca, S, Waltenspuhl, Y, Schoppe, J, Medalia, O, Pluckthun, A.
Deposit date:2021-06-29
Release date:2021-12-15
Method:ELECTRON MICROSCOPY (2.87 Å)
Cite:Structures of neurokinin 1 receptor in complex with G q and G s proteins reveal substance P binding mode and unique activation features.
Sci Adv, 7, 2021
7QVM
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BU of 7qvm by Molmil
Human Oxytocin receptor (OTR) oxytocin Gq chimera (mGoqi) complex
Descriptor: Antibody fragment scFv16, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
Authors:Waltenspuhl, Y, Ehrenmann, J, Vacca, S, Thom, C, Medalia, O, Pluckthun, A.
Deposit date:2022-01-21
Release date:2022-08-10
Method:ELECTRON MICROSCOPY (3.25 Å)
Cite:Structural basis for the activation and ligand recognition of the human oxytocin receptor.
Nat Commun, 13, 2022
5OGI
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BU of 5ogi by Molmil
Complex of a binding protein and human adenovirus C 5 hexon
Descriptor: 1,2-ETHANEDIOL, 1,4-DIETHYLENE DIOXIDE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ...
Authors:Schmid, M, Ernst, P, Honegger, A, Suomalainen, M, Zimmermann, M, Braun, L, Stauffer, S, Thom, C, Dreier, B, Eibauer, M, Kipar, A, Vogel, V, Greber, U.F, Medalia, O, Plueckthun, A.
Deposit date:2017-07-13
Release date:2018-02-07
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Adenoviral vector with shield and adapter increases tumor specificity and escapes liver and immune control.
Nat Commun, 9, 2018
6TEK
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BU of 6tek by Molmil
Structure of siderophore interaction domain of IrtAB
Descriptor: Drug ABC transporter ATP-binding protein, FLAVIN-ADENINE DINUCLEOTIDE
Authors:Arnold, F.M, Gonda, I, Hutter, C.A.J, Seeger, M.A, Hurlimann, L.M.
Deposit date:2019-11-12
Release date:2020-04-01
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The ABC exporter IrtAB imports and reduces mycobacterial siderophores.
Nature, 580, 2020
6TEJ
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BU of 6tej by Molmil
Structure of apo IrtAB devoid SID in complex with sybody Syb_NL5
Descriptor: DECYL-BETA-D-MALTOPYRANOSIDE, Drug ABC transporter ATP-binding protein, NICKEL (II) ION, ...
Authors:Gonda, I, Arnold, F.M, Hutter, C.A.J, Weber, M.S, Seeger, M.A, Hurlimann, L.M.
Deposit date:2019-11-12
Release date:2020-04-01
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The ABC exporter IrtAB imports and reduces mycobacterial siderophores.
Nature, 580, 2020
6R4P
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BU of 6r4p by Molmil
Structure of a soluble domain of adenylyl cyclase bound to an activated stimulatory G protein
Descriptor: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, Adenylate cyclase 9, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ...
Authors:Korkhov, V.M, Qi, C.
Deposit date:2019-03-22
Release date:2019-05-08
Last modified:2019-11-06
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:The structure of a membrane adenylyl cyclase bound to an activated stimulatory G protein.
Science, 364, 2019
6R3Q
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BU of 6r3q by Molmil
The structure of a membrane adenylyl cyclase bound to an activated stimulatory G protein
Descriptor: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, Adenylate cyclase 9, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ...
Authors:Korkhov, V.M, Qi, C.
Deposit date:2019-03-20
Release date:2019-05-08
Last modified:2019-11-06
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:The structure of a membrane adenylyl cyclase bound to an activated stimulatory G protein.
Science, 364, 2019

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