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1N7N
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STREPTOCOCCUS PNEUMONIAE HYALURONATE LYASE W292A MUTANT
Descriptor:HYALURONIDASE
Authors:Nukui, M., Taylor, K.B., McPherson, D.T., Shigenaga, M., Jedrzejas, M.J.
Deposit date:2002-11-16
Release date:2002-12-31
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:The function of hydrophobic residues in the catalytic cleft of Streptococcus pneumoniae hyaluronate lyase. Kinetic characterization of mutant enzyme forms
J.Biol.Chem., 278, 2003
1N7O
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STREPTOCOCCUS PNEUMONIAE HYALURONATE LYASE F343V MUTANT
Descriptor:hyaluronidase
Authors:Nukui, M., Taylor, K.B., McPherson, D.T., Shigenaga, M., Jedrzejas, M.J.
Deposit date:2002-11-16
Release date:2002-12-31
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:The function of hydrophobic residues in the catalytic cleft of Streptococcus pneumoniae hyaluronate lyase. Kinetic characterization of mutant enzyme forms
J.Biol.Chem., 278, 2003
1N7P
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STREPTOCOCCUS PNEUMONIAE HYALURONATE LYASE W292A/F343V DOUBLE MUTANT
Descriptor:HYALURONIDASE
Authors:Nukui, M., Taylor, K.B., McPherson, D.T., Shigenaga, M., Jedrzejas, M.J.
Deposit date:2002-11-16
Release date:2002-12-31
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:The function of hydrophobic residues in the catalytic cleft of Streptococcus pneumoniae hyaluronate lyase. Kinetic characterization of mutant enzyme forms
J.Biol.Chem., 278, 2003
1N7Q
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STREPTOCOCCUS PNEUMONIAE HYALURONATE LYASE W291A/W292A DOUBLE MUTANT COMPLEX WITH HYALURONAN HEXASACCHRIDE
Descriptor:HYALURONIDASE, N-ACETYL-D-GLUCOSAMINE, BETA-D-GLUCOPYRANURONIC ACID, ...
Authors:Nukui, M., Taylor, K.B., McPherson, D.T., Shigenaga, M., Jedrzejas, M.J.
Deposit date:2002-11-16
Release date:2002-12-31
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The function of hydrophobic residues in the catalytic cleft of Streptococcus pneumoniae hyaluronate lyase. Kinetic characterization of mutant enzyme forms
J.Biol.Chem., 278, 2003
1N7R
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STREPTOCOCCUS PNEUMONIAE HYALURONATE LYASE W291A/W292A/F343V MUTANT COMPLEX WITH HEXASACCHARIDE HYALURONAN
Descriptor:HYALURONIDASE, N-ACETYL-D-GLUCOSAMINE, BETA-D-GLUCOPYRANURONIC ACID
Authors:Nukui, M., Taylor, K.B., McPherson, D.T., Shigenaga, M., Jedrzejas, M.J.
Deposit date:2002-11-16
Release date:2002-12-31
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The function of hydrophobic residues in the catalytic cleft of Streptococcus pneumoniae hyaluronate lyase. Kinetic characterization of mutant enzyme forms
J.Biol.Chem., 278, 2003
1OTX
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PURINE NUCLEOSIDE PHOSPHORYLASE M64V MUTANT
Descriptor:Purine nucleoside phosphorylase, PHOSPHATE ION
Authors:Ealick, S.E., Bennett, E.M., Anand, R., Secrist, J.A., Parker, W.B., Hassan, A.E., Allan, P.W., McPherson, D.T., Sorscher, E.J.
Deposit date:2003-03-23
Release date:2004-02-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Designer gene therapy using an Escherichia coli purine nucleoside phosphorylase/prodrug system.
Chem.Biol., 10, 2003
1OTY
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NATIVE PNP +ALLO
Descriptor:Purine nucleoside phosphorylase, PHOSPHATE ION, 6-METHYLPURINE
Authors:Ealick, S.E., Bennett, E.M., Anand, R., Secrist, J.A., Parker, W.B., Hassan, A.E., Allan, P.W., McPherson, D.T., Sorscher, E.J.
Deposit date:2003-03-23
Release date:2004-02-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Designer gene therapy using an Escherichia coli purine nucleoside phosphorylase/prodrug system.
Chem.Biol., 10, 2003
1OU4
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NATIVE PNP +TALO
Descriptor:Purine nucleoside phosphorylase, PHOSPHATE ION, 6-METHYLPURINE
Authors:Ealick, S.E., Bennett, E.M., Anand, R., Secrist, J.A., Parker, W.B., Hassan, A.E., Allan, P.W., McPherson, D.T., Sorscher, E.J.
Deposit date:2003-03-24
Release date:2004-02-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Designer gene therapy using an Escherichia coli purine nucleoside phosphorylase/prodrug system.
Chem.Biol., 10, 2003
1OUM
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M64V PNP +TALO
Descriptor:Purine nucleoside phosphorylase, 9-(6-DEOXY-ALPHA-L-TALOFURANOSYL)-6-METHYLPURINE, PHOSPHATE ION
Authors:Ealick, S.E., Bennett, E.M., Anand, R., Secrist, J.A., Parker, W.B., Hassan, A.E., Allan, P.W., McPherson, D.T., Sorscher, E.J.
Deposit date:2003-03-24
Release date:2004-02-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Designer gene therapy using an Escherichia coli purine nucleoside phosphorylase/prodrug system.
Chem.Biol., 10, 2003
1OV6
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M64V PNP + ALLO
Descriptor:Purine nucleoside phosphorylase, PHOSPHATE ION, 9-(6-DEOXY-BETA-D-ALLOFURANOSYL)-6-METHYLPURINE
Authors:Ealick, S.E., Bennett, E.M., Anand, R., Secrist, J.A., Parker, P.W., Hassan, A.E., Allan, P.W., McPherson, D.T., Sorscher, E.J.
Deposit date:2003-03-25
Release date:2004-02-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Designer gene therapy using an Escherichia coli purine nucleoside phosphorylase/prodrug system.
Chem.Biol., 10, 2003
1OVG
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M64V PNP +MEPDR
Descriptor:Purine nucleoside phosphorylase, PHOSPHATE ION, 9-(2-DEOXY-BETA-D-RIBOFURANOSYL)-6-METHYLPURINE
Authors:Ealick, S.E., Bennett, E.M., Anand, R., Secrist, J.A., Parker, P.W., Hassan, A.E., Allan, P.W., McPherson, D.T., Sorscher, E.J.
Deposit date:2003-03-26
Release date:2004-02-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Designer gene therapy using an Escherichia coli purine nucleoside phosphorylase/prodrug system.
Chem.Biol., 10, 2003