Author results

4YJ2
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CRYSTAL STRUCTURE OF TUBULIN BOUND TO MI-181
Descriptor:Tubulin alpha-1B chain, Tubulin beta-2B chain, Stathmin-4, ...
Authors:McNamara, D.E., Torres, J.Z., Yeates, T.O.
Deposit date:2015-03-03
Release date:2015-05-27
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structures of potent anticancer compounds bound to tubulin.
Protein Sci., 24, 2015
4YJ3
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CRYSTAL STRUCTURE OF TUBULIN BOUND TO COMPOUND 2
Descriptor:Tubulin alpha-1B chain, Tubulin beta-2B chain, Stathmin-4, ...
Authors:McNamara, D.E., Torres, J.Z., Yeates, T.O.
Deposit date:2015-03-03
Release date:2015-05-27
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (3.75 Å)
Cite:Structures of potent anticancer compounds bound to tubulin.
Protein Sci., 24, 2015
6D74
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DIRECT ACTIVATION OF THE EXECUTIONER DOMAIN OF MLKL BY A SELECT REPERTOIRE OF INOSITOL PHOSPHATES
Descriptor:Mixed lineage kinase domain-like protein
Authors:Royappa, G.C., McNamara, D.E., Moldoveanu, T.
Deposit date:2018-04-24
Release date:2019-05-15
Last modified:2019-07-03
Method:SOLUTION NMR
Cite:Direct Activation of Human MLKL by a Select Repertoire of Inositol Phosphate Metabolites.
Cell Chem Biol, 26, 2019
3WIS
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CRYSTAL STRUCTURE OF BURKHOLDERIA XENOVORANS DMRB IN COMPLEX WITH FMN: A CUBIC PROTEIN CAGE FOR REDOX TRANSFER
Descriptor:Putative dihydromethanopterin reductase (AfpA), FLAVIN MONONUCLEOTIDE, SULFATE ION
Authors:Bobik, T.A., Cascio, D., Jorda, J., McNamara, D.E., Bustos, C., Wang, T.C., Rasche, M.E., Yeates, T.O.
Deposit date:2013-09-25
Release date:2014-02-19
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.901 Å)
Cite:Structure of dihydromethanopterin reductase, a cubic protein cage for redox transfer
J.Biol.Chem., 289, 2014
4MWG
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CRYSTAL STRUCTURE OF BURKHOLDERIA XENOVORANS DMRB APO FORM: A CUBIC PROTEIN CAGE FOR REDOX TRANSFER
Descriptor:Putative dihydromethanopterin reductase (AfpA), SULFATE ION
Authors:Bobik, T.A., Cascio, D., Jorda, J., McNamara, D.E., Bustos, C., Wang, T.C., Rasche, M.E., Yeates, T.O.
Deposit date:2013-09-24
Release date:2014-02-19
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of dihydromethanopterin reductase, a cubic protein cage for redox transfer
J.Biol.Chem., 289, 2014
4NWN
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COMPUTATIONALLY DESIGNED TWO-COMPONENT SELF-ASSEMBLING TETRAHEDRAL CAGE T32-28
Descriptor:Uncharacterized protein, Propanediol utilization: polyhedral bodies pduT
Authors:McNamara, D.E., King, N.P., Bale, J.B., Sheffler, W., Baker, D., Yeates, T.O.
Deposit date:2013-12-06
Release date:2014-05-28
Last modified:2014-06-11
Method:X-RAY DIFFRACTION (4.5 Å)
Cite:Accurate design of co-assembling multi-component protein nanomaterials.
Nature, 510, 2014
4NWO
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COMPUTATIONALLY DESIGNED TWO-COMPONENT SELF-ASSEMBLING TETRAHEDRAL CAGE T33-15
Descriptor:Molybdenum cofactor biosynthesis protein MogA, Chorismate mutase AroH, CALCIUM ION
Authors:McNamara, D.E., King, N.P., Bale, J.B., Sheffler, W., Baker, D., Yeates, T.O.
Deposit date:2013-12-06
Release date:2014-05-28
Last modified:2014-06-11
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Accurate design of co-assembling multi-component protein nanomaterials.
Nature, 510, 2014
4NWP
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COMPUTATIONALLY DESIGNED TWO-COMPONENT SELF-ASSEMBLING TETRAHEDRAL CAGE, T33-21, CRYSTALLIZED IN SPACE GROUP R32
Descriptor:Putative uncharacterized protein, Uncharacterized protein, SULFATE ION, ...
Authors:McNamara, D.E., King, N.P., Bale, J.B., Sheffler, W., Baker, D., Yeates, T.O.
Deposit date:2013-12-06
Release date:2014-05-28
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Accurate design of co-assembling multi-component protein nanomaterials.
Nature, 510, 2014
4NWQ
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COMPUTATIONALLY DESIGNED TWO-COMPONENT SELF-ASSEMBLING TETRAHEDRAL CAGE, T33-21, CRYSTALLIZED IN SPACE GROUP F4132
Descriptor:Putative uncharacterized protein PH0671, Uncharacterized protein, SULFATE ION
Authors:McNamara, D.E., King, N.P., Bale, J.B., Sheffler, W., Baker, D., Yeates, T.O.
Deposit date:2013-12-06
Release date:2014-05-28
Last modified:2014-06-11
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Accurate design of co-assembling multi-component protein nanomaterials.
Nature, 510, 2014
4NWR
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COMPUTATIONALLY DESIGNED TWO-COMPONENT SELF-ASSEMBLING TETRAHEDRAL CAGE T33-28
Descriptor:integron gene cassette protein, Macrophage migration inhibitory factor-like protein
Authors:McNamara, D.E., King, N.P., Bale, J.B., Sheffler, W., Baker, D., Yeates, T.O.
Deposit date:2013-12-06
Release date:2014-05-28
Last modified:2014-12-10
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Accurate design of co-assembling multi-component protein nanomaterials.
Nature, 510, 2014
4PPD
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PDUA K26A, CRYSTAL FORM 2
Descriptor:Propanediol utilization protein PduA, SULFATE ION, GLYCEROL
Authors:McNamara, D.E., Sawaya, M.R., Bobik, T.A., Yeates, T.O.
Deposit date:2014-02-26
Release date:2014-05-14
Last modified:2014-06-04
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Alanine scanning mutagenesis identifies an asparagine-arginine-lysine triad essential to assembly of the shell of the pdu microcompartment.
J.Mol.Biol., 426, 2014
5HS0
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COMPUTATIONALLY DESIGNED CYCLIC TETRAMER ANK1C4_7
Descriptor:Ankyrin domain protein ank1C4_7, SULFATE ION, GLYCEROL
Authors:McNamara, D.E., Cascio, D., Fallas, J.A., Baker, D., Yeates, T.O.
Deposit date:2016-01-24
Release date:2017-04-12
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Computational design of self-assembling cyclic protein homo-oligomers.
Nat Chem, 9, 2017
4P2S
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ALANINE SCANNING MUTAGENESIS IDENTIFIES AN ASPARAGINE-ARGININE-LYSINE TRIAD ESSENTIAL TO ASSEMBLY OF THE SHELL OF THE PDU MICROCOMPARTMENT
Descriptor:Putative propanediol utilization protein PduA, SULFATE ION, GLYCEROL, ...
Authors:Sinha, S., Cheng, S., Sung, Y.W., McNamara, D.E., Sawaya, M.R., Yeates, T.O., Bobik, T.A.
Deposit date:2014-03-03
Release date:2014-05-14
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Alanine Scanning Mutagenesis Identifies an Asparagine-Arginine-Lysine Triad Essential to Assembly of the Shell of the Pdu Microcompartment.
J.Mol.Biol., 426, 2014
5HRY
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COMPUTATIONALLY DESIGNED CYCLIC DIMER ANK3C2_1
Descriptor:ank3C2_1
Authors:Cascio, D., McNamara, D.E., Fallas, J.A., Baker, D., Yeates, T.O.
Deposit date:2016-01-24
Release date:2017-04-12
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Computational design of self-assembling cyclic protein homo-oligomers.
Nat Chem, 9, 2017
5HRZ
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COMPUTATIONALLY DESIGNED TRIMER 1NA0C3_3
Descriptor:TPR domain protein 1na0C3_3
Authors:Cascio, D., McNamara, D.E., Fallas, J.A., Baker, D., Yeates, T.O.
Deposit date:2016-01-24
Release date:2017-04-12
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Computational design of self-assembling cyclic protein homo-oligomers.
Nat Chem, 9, 2017
4GMR
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CRYSTAL STRUCTURE OF ENGINEERED PROTEIN. NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET OR266.
Descriptor:OR266 DE NOVO PROTEIN, NITRATE ION
Authors:Vorobiev, S., Su, M., Parmeggiani, F., Seetharaman, J., Huang, P.-S., Mao, M., Xiao, R., Lee, D., Everett, J.K., Acton, T.B., Baker, D., Montelione, G.T., Tong, L., Hunt, J.F., Northeast Structural Genomics Consortium (NESG)
Deposit date:2012-08-16
Release date:2012-08-29
Last modified:2017-04-12
Method:X-RAY DIFFRACTION (2.377 Å)
Cite:Computational design of self-assembling cyclic protein homo-oligomers.
NAT.CHEM., 9, 2017
4GPM
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CRYSTAL STRUCTURE OF ENGINEERED PROTEIN. NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET OR264.
Descriptor:Engineered Protein OR264
Authors:Vorobiev, S., Su, M., Parmeggiani, F., Seetharaman, J., Huang, P.-S., Maglaqui, M., Xiao, R., Lee, D., Everett, J.K., Acton, T.B., Baker, D., Montelione, G.T., Tong, L., Hunt, J.F., Northeast Structural Genomics Consortium (NESG)
Deposit date:2012-08-21
Release date:2012-09-05
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.002 Å)
Cite:Computational design of self-assembling cyclic protein homo-oligomers.
NAT.CHEM., 9, 2017
4HB5
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CRYSTAL STRUCTURE OF ENGINEERED PROTEIN. NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET OR267.
Descriptor:Engineered Protein
Authors:Vorobiev, S., Su, M., Parmeggiani, F., Seetharaman, J., Huang, P.-S., Maglaqui, M., Xiao, R., Lee, D., Everett, J.K., Acton, T.B., Baker, D., Montelione, G.T., Tong, L., Hunt, J.F., Northeast Structural Genomics Consortium (NESG)
Deposit date:2012-09-27
Release date:2012-10-10
Last modified:2017-04-12
Method:X-RAY DIFFRACTION (2.294 Å)
Cite:Computational design of self-assembling cyclic protein homo-oligomers.
NAT.CHEM., 9, 2017
4HXT
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CRYSTAL STRUCTURE OF ENGINEERED PROTEIN. NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET OR329
Descriptor:De Novo Protein OR329
Authors:Vorobiev, S., Su, M., Parmeggiani, F., Seetharaman, J., Huang, P.-S., Maglaqui, M., Xiao, X., Lee, D., Everett, J.K., Acton, T.B., Baker, D., Montelione, G.T., Tong, L., Hunt, J.F., Northeast Structural Genomics Consortium (NESG)
Deposit date:2012-11-12
Release date:2012-11-21
Last modified:2017-04-12
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Computational design of self-assembling cyclic protein homo-oligomers.
NAT.CHEM., 9, 2017
5K7V
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COMPUTATIONAL DESIGN OF SELF-ASSEMBLING CYCLIC PROTEIN HOMOOLIGOMERS
Descriptor:Designed protein HR00C3
Authors:Sankaran, B., Zwart, P.H., Fallas, J.A., Pereira, J.H., Ueda, G., Baker, D.
Deposit date:2016-05-26
Release date:2017-04-12
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (3.165 Å)
Cite:Computational design of self-assembling cyclic protein homo-oligomers.
Nat Chem, 9, 2017
5KBA
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COMPUTATIONAL DESIGN OF SELF-ASSEMBLING CYCLIC PROTEIN HOMOOLIGOMERS
Descriptor:Designed protein ANK1C2
Authors:Sankaran, B., Zwart, P.H., Fallas, J.A., Pereira, J.H., Ueda, G., Baker, D.
Deposit date:2016-06-02
Release date:2017-04-12
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.601 Å)
Cite:Computational design of self-assembling cyclic protein homo-oligomers.
Nat Chem, 9, 2017
5KWD
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COMPUTATIONALLY DESIGNED SYMMETRIC HOMOTETRAMER
Descriptor:Ankyrin repeat-containing protein
Authors:Fallas, J.A., Sankaran, B., Zwart, P., Baker, D.
Deposit date:2016-07-17
Release date:2017-04-12
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Computational design of self-assembling cyclic protein homo-oligomers.
Nat Chem, 9, 2017
6CKV
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SOLUTION NMR STRUCTURE OF HUMAN BOK
Descriptor:Bcl-2-related ovarian killer protein
Authors:Grace, C.R., Zheng, J., Moldoveanu, T.
Deposit date:2018-03-01
Release date:2018-05-09
Last modified:2018-07-04
Method:SOLUTION NMR
Cite:Intrinsic Instability of BOK Enables Membrane Permeabilization in Apoptosis.
Cell Rep, 23, 2018