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2XMY
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DISCOVERY AND CHARACTERISATION OF 2-ANILINO-4-(THIAZOL-5-YL) PYRIMIDINE TRANSCRIPTIONAL CDK INHIBITORS AS ANTICANCER AGENTS
Descriptor:CELL DIVISION PROTEIN KINASE 2, 4-[4-(3,4-DIMETHYL-2-OXO-2,3-DIHYDRO-THIAZOL-5-YL)-PYRIMIDIN-2-YLAMINO]-N-(2-METHOXY-ETHYL)-BENZENESULFONAMIDE
Authors:Wang, S., Griffiths, G., Midgley, C.A., Barnett, A.L., Cooper, M., Grabarek, J., Ingram, L., Jackson, W., Kontopidis, G., McClue, S.J., McInnes, C., McLachlan, J., Meades, C., Mezna, M., Stuart, I., Thomas, M.P., Zheleva, D.I., Lane, D.P., Jackson, R.C., Glover, D.M., Blake, D.G., Fischer, P.M.
Deposit date:2010-07-29
Release date:2010-11-10
Last modified:2012-03-28
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Discovery and Characterisation of 2-Anilino-4-(Thiazol-5-Yl)Pyrimidine Transcriptional Cdk Inhibitors as Anticancer Agents
Chem.Biol., 17, 2010
2XNB
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DISCOVERY AND CHARACTERISATION OF 2-ANILINO-4-(THIAZOL-5-YL) PYRIMIDINE TRANSCRIPTIONAL CDK INHIBITORS AS ANTICANCER AGENTS
Descriptor:CELL DIVISION PROTEIN KINASE 2, 3,4-DIMETHYL-5-(2-{[(1Z)-4-PIPERAZIN-1-YLCYCLOHEXA-2,4-DIEN-1-YLIDENE]AMINO}PYRIMIDIN-4-YL)-1,3-THIAZOL-2(3H)-ONE
Authors:Wang, S., Griffiths, G., Midgley, C.A., Barnett, A.L., Cooper, M., Grabarek, J., Ingram, L., Jackson, W., Kontopidis, G., McClue, S.J., McInnes, C., McLachlan, J., Meades, C., Mezna, M., Stuart, I., Thomas, M.P., Zheleva, D.I., Lane, D.P., Jackson, R.C., Glover, D.M., Blake, D.G., Fischer, P.M.
Deposit date:2010-08-01
Release date:2010-11-10
Last modified:2012-03-28
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Discovery and Characterisation of 2-Anilino-4-(Thiazol-5-Yl)Pyrimidine Transcriptional Cdk Inhibitors as Anticancer Agents
Chem.Biol., 17, 2010
1M8W
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CRYSTAL STRUCTURE OF THE PUMILIO-HOMOLOGY DOMAIN FROM HUMAN PUMILIO1 IN COMPLEX WITH NRE1-19 RNA
Descriptor:5'-R(P*UP*UP*GP*UP*AP*UP*AP*U)-3', 5'-R(P*UP*GP*UP*AP*UP*AP*U)-3', 5'-R(P*UP*UP*GP*UP*CP*CP*AP*G)-3', ...
Authors:Wang, X., McLachlan, J., Zamore, P.D., Hall, T.M.T.
Deposit date:2002-07-26
Release date:2002-09-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:MODULAR RECOGNITION OF RNA BY A HUMAN PUMILIO-HOMOLOGY DOMAIN
CELL(CAMBRIDGE,MASS.), 110, 2002
1M8X
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CRYSTAL STRUCTURE OF THE PUMILIO-HOMOLOGY DOMAIN FROM HUMAN PUMILIO1 IN COMPLEX WITH NRE1-14 RNA
Descriptor:5'-R(P*UP*UP*GP*UP*AP*UP*AP*U)-3', 5'-R(P*UP*GP*UP*AP*UP*AP*U)-3', Pumilio 1
Authors:Wang, X., McLachlan, J., Zamore, P.D., Hall, T.M.T.
Deposit date:2002-07-26
Release date:2002-09-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:MODULAR RECOGNITION OF RNA BY A HUMAN PUMILIO-HOMOLOGY DOMAIN
CELL(CAMBRIDGE,MASS.), 110, 2002
1M8Y
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CRYSTAL STRUCTURE OF THE PUMILIO-HOMOLOGY DOMAIN FROM HUMAN PUMILIO1 IN COMPLEX WITH NRE2-10 RNA
Descriptor:5'-R(P*AP*UP*UP*GP*UP*AP*CP*AP*UP*A)-3', Pumilio 1
Authors:Wang, X., McLachlan, J., Zamore, P.D., Hall, T.M.T.
Deposit date:2002-07-26
Release date:2002-09-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:MODULAR RECOGNITION OF RNA BY A HUMAN PUMILIO-HOMOLOGY DOMAIN
CELL(CAMBRIDGE,MASS.), 110, 2002
1M8Z
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CRYSTAL STRUCTURE OF A PUMILIO-HOMOLOGY DOMAIN
Descriptor:PUMILIO 1, BETA-MERCAPTOETHANOL
Authors:Wang, X., Zamore, P.D., Hall, T.M.T.
Deposit date:2002-07-26
Release date:2002-09-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of a Pumilio homology domain.
Mol.Cell, 7, 2001