Author results

1CX1
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SECOND N-TERMINAL CELLULOSE-BINDING DOMAIN FROM CELLULOMONAS FIMI BETA-1,4-GLUCANASE C, NMR, 22 STRUCTURES
Descriptor:ENDOGLUCANASE C
Authors:Brun, E., Johnson, P.E., Creagh, L.A., Haynes, C.A., Tomme, P., Webster, P., Kilburn, D.G., McIntosh, L.P.
Deposit date:1999-08-27
Release date:2000-04-02
Last modified:2017-02-01
Method:SOLUTION NMR
Cite:Structure and binding specificity of the second N-terminal cellulose-binding domain from Cellulomonas fimi endoglucanase C.
Biochemistry, 39, 2000
1GGW
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CDC4P FROM SCHIZOSACCHAROMYCES POMBE
Descriptor:PROTEIN (CDC4P)
Authors:Slupsky, C.M., Hemmingsen, S.M., McIntosh, L.P.
Deposit date:2000-09-25
Release date:2001-03-21
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure of Cdc4p, a contractile ring protein essential for cytokinesis in Schizosaccharomyces pombe.
J.Biol.Chem., 276, 2001
1ULO
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N-TERMINAL CELLULOSE-BINDING DOMAIN FROM CELLULOMONAS FIMI BETA-1,4-GLUCANASE C, NMR, MINIMIZED AVERAGE STRUCTURE
Descriptor:ENDOGLUCANASE C
Authors:Johnson, P.E., Mcintosh, L.P.
Deposit date:1996-07-27
Release date:1997-04-01
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure of the N-terminal cellulose-binding domain of Cellulomonas fimi CenC determined by nuclear magnetic resonance spectroscopy.
Biochemistry, 35, 1996
1ULP
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N-TERMINAL CELLULOSE-BINDING DOMAIN FROM CELLULOMONAS FIMI BETA-1,4-GLUCANASE C, NMR, 25 STRUCTURES
Descriptor:ENDOGLUCANASE C
Authors:Johnson, P.E., Mcintosh, L.P.
Deposit date:1996-07-27
Release date:1997-04-01
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure of the N-terminal cellulose-binding domain of Cellulomonas fimi CenC determined by nuclear magnetic resonance spectroscopy.
Biochemistry, 35, 1996
1HV0
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DISSECTING ELECTROSTATIC INTERACTIONS AND THE PH-DEPENDENT ACTIVITY OF A FAMILY 11 GLYCOSIDASE
Descriptor:ENDO-1,4-BETA-XYLANASE
Authors:Joshi, M.D., Sidhu, G., Nielsen, J.E., Brayer, G.D., Withers, S.G., McIntosh, L.P.
Deposit date:2001-01-05
Release date:2001-09-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Dissecting the electrostatic interactions and pH-dependent activity of a family 11 glycosidase.
Biochemistry, 40, 2001
1C5H
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HYDROGEN BONDING AND CATALYSIS: AN UNEXPECTED EXPLANATION FOR HOW A SINGLE AMINO ACID SUBSTITUTION CAN CHANGE THE PH OPTIMUM OF A GLYCOSIDASE
Descriptor:ENDO-1,4-BETA-XYLANASE
Authors:Joshi, M.D., Sidhu, G., Pot, I., Brayer, G.D., Withers, S.G., Mcintosh, L.P.
Deposit date:1999-11-24
Release date:2000-05-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Hydrogen bonding and catalysis: a novel explanation for how a single amino acid substitution can change the pH optimum of a glycosidase.
J.Mol.Biol., 299, 2000
1C5I
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HYDROGEN BONDING AND CATALYSIS: AN UNEXPECTED EXPLANATION FOR HOW A SINGLE AMINO ACID SUBSTITUTION CAN CHANGE THE PH OPTIMUM OF A GLYCOSIDASE
Descriptor:ENDO-1,4-BETA-XYLANASE, BETA-D-XYLOPYRANOSE, 1,2-DEOXY-2-FLUORO-XYLOPYRANOSE
Authors:Joshi, M.D., Sidhu, G., Pot, I., Brayer, G.D., Withers, S.G., Mcintosh, L.P.
Deposit date:1999-11-24
Release date:2000-05-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Hydrogen bonding and catalysis: a novel explanation for how a single amino acid substitution can change the pH optimum of a glycosidase.
J.Mol.Biol., 299, 2000
1EF4
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SOLUTION STRUCTURE OF THE ESSENTIAL RNA POLYMERASE SUBUNIT RPB10 FROM METHANOBACTERIUM THERMOAUTOTROPHICUM
Descriptor:DNA-DIRECTED RNA POLYMERASE, ZINC ION
Authors:Mackereth, C.D., Arrowsmith, C.H., Edwards, A.M., Mcintosh, L.P., Northeast Structural Genomics Consortium (NESG)
Deposit date:2000-02-07
Release date:2000-06-14
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Zinc-bundle structure of the essential RNA polymerase subunit RPB10 from Methanobacterium thermoautotrophicum.
Proc.Natl.Acad.Sci.USA, 97, 2000
1HV1
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DISSECTING ELECTROSTATIC INTERACTIONS AND THE PH-DEPENDENT ACTIVITY OF A FAMILY 11 GLYCOSIDASE
Descriptor:ENDO-1,4-BETA-XYLANASE
Authors:Joshi, M.D., Sidhu, G., Nielsen, J.E., Brayer, G.D., Withers, S.G., McIntosh, L.P.
Deposit date:2001-01-05
Release date:2001-09-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Dissecting the electrostatic interactions and pH-dependent activity of a family 11 glycosidase.
Biochemistry, 40, 2001
1IIO
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NMR-BASED STRUCTURE OF THE CONSERVED PROTEIN MTH865 FROM THE ARCHEA METHANOBACTERIUM THERMOAUTOTROPHICUM
Descriptor:conserved hypothetical protein MTH865
Authors:Lee, G.M., Edwards, A.M., Arrowsmith, C.H., McIntosh, L.P.
Deposit date:2001-04-23
Release date:2001-10-17
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:NMR-based structure of the conserved protein MTH865 from the archaeon Methanobacterium thermoautotrophicum.
J.Biomol.NMR, 21, 2001
1L00
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PERTURBATION OF TRP 138 IN T4 LYSOZYME BY MUTATIONS AT GLN 105 USED TO CORRELATE CHANGES IN STRUCTURE, STABILITY, SOLVATION, AND SPECTROSCOPIC PROPERTIES
Descriptor:T4 LYSOZYME, BETA-MERCAPTOETHANOL
Authors:Pjura, P., Mcintosh, L.P., Wozniak, J.A., Matthews, B.W.
Deposit date:1992-07-13
Release date:1993-10-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Perturbation of Trp 138 in T4 lysozyme by mutations at Gln 105 used to correlate changes in structure, stability, solvation, and spectroscopic properties.
Proteins, 15, 1993
1L98
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PERTURBATION OF TRP 138 IN T4 LYSOZYME BY MUTATIONS AT GLN 105 USED TO CORRELATE CHANGES IN STRUCTURE, STABILITY, SOLVATION, AND SPECTROSCOPIC PROPERTIES
Descriptor:T4 LYSOZYME, BETA-MERCAPTOETHANOL
Authors:Pjura, P., Mcintosh, L.P., Wozniak, J.A., Matthews, B.W.
Deposit date:1992-07-13
Release date:1993-10-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Perturbation of Trp 138 in T4 lysozyme by mutations at Gln 105 used to correlate changes in structure, stability, solvation, and spectroscopic properties.
Proteins, 15, 1993
1L99
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PERTURBATION OF TRP 138 IN T4 LYSOZYME BY MUTATIONS AT GLN 105 USED TO CORRELATE CHANGES IN STRUCTURE, STABILITY, SOLVATION, AND SPECTROSCOPIC PROPERTIES
Descriptor:T4 LYSOZYME, BETA-MERCAPTOETHANOL
Authors:Pjura, P., Mcintosh, L.P., Wozniak, J.A., Matthews, B.W.
Deposit date:1992-07-13
Release date:1993-10-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Perturbation of Trp 138 in T4 lysozyme by mutations at Gln 105 used to correlate changes in structure, stability, solvation, and spectroscopic properties.
Proteins, 15, 1993
1R36
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NMR-BASED STRUCTURE OF AUTOINHIBITED MURINE ETS-1 DELTAN301
Descriptor:C-ets-1 protein
Authors:Lee, G.M., Donaldson, L.W., Pufall, M.A., Kang, H.-S., Pot, I., Graves, B.J., McIntosh, L.P.
Deposit date:2003-09-30
Release date:2004-11-09
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:The Structural and Dynamic Basis of Ets-1 DNA Binding Autoinhibition
J.Biol.Chem., 280, 2005
1RYJ
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SOLUTION NMR STRUCTURE OF PROTEIN MTH1743 FROM METHANOBACTERIUM THERMOAUTOTROPHICUM. ONTARIO CENTRE FOR STRUCTURAL PROTEOMICS TARGET MTH1743_1_70; NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET TT526.
Descriptor:unknown
Authors:Yee, A., Chang, X., Pineda-Lucena, A., Wu, B., Semesi, A., Le, B., Ramelot, T., Lee, G.M., Bhattacharyya, S., Gutierrez, P., Denisov, A., Lee, C.H., Cort, J.R., Kozlov, G., Liao, J., Finak, G., Chen, L., Wishart, D., Lee, W., McIntosh, L.P., Gehring, K., Kennedy, M.A., Edwards, A.M., Arrowsmith, C.H., Northeast Structural Genomics Consortium (NESG)
Deposit date:2003-12-22
Release date:2004-02-24
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:AN NMR APPROACH TO STRUCTURAL PROTEOMICS
Proc.Natl.Acad.Sci.USA, 99, 2002
1SLJ
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SOLUTION STRUCTURE OF THE S1 DOMAIN OF RNASE E FROM E. COLI
Descriptor:Ribonuclease E
Authors:Schubert, M., Edge, R.E., Lario, P., Cook, M.A., Strynadka, N.C.J., Mackie, G.A., McIntosh, L.P.
Deposit date:2004-03-05
Release date:2004-08-17
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structural characterization of the RNase E S1 domain and identification of its oligonucleotide-binding and dimerization interfaces.
J.Mol.Biol., 341, 2004
1SMX
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CRYSTAL STRUCTURE OF THE S1 DOMAIN OF RNASE E FROM E. COLI (NATIVE)
Descriptor:Ribonuclease E
Authors:Schubert, M., Edge, R.E., Lario, P., Cook, M.A., Strynadka, N.C.J., Mackie, G.A., McIntosh, L.P.
Deposit date:2004-03-09
Release date:2004-08-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural characterization of the RNase E S1 domain and identification of its oligonucleotide-binding and dimerization interfaces.
J.Mol.Biol., 341, 2004
1SN8
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CRYSTAL STRUCTURE OF THE S1 DOMAIN OF RNASE E FROM E. COLI (PB DERIVATIVE)
Descriptor:Ribonuclease E, LEAD (II) ION
Authors:Schubert, M., Edge, R.E., Lario, P., Cook, M.A., Strynadka, N.C.J., Mackie, G.A., McIntosh, L.P.
Deposit date:2004-03-10
Release date:2004-08-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural characterization of the RNase E S1 domain and identification of its oligonucleotide-binding and dimerization interfaces.
J.Mol.Biol., 341, 2004
1SXD
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SOLUTION STRUCTURE OF THE POINTED (PNT) DOMAIN FROM MGABPA
Descriptor:GA repeat binding protein, alpha
Authors:Mackereth, C.D., Schaerpf, M., Gentile, L.N., MacIntosh, S.E., Slupsky, C.M., McIntosh, L.P.
Deposit date:2004-03-30
Release date:2004-09-21
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Diversity in Structure and Function of the Ets Family PNT Domains.
J.Mol.Biol., 342, 2004
1SXE
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THE SOLUTION STRUCTURE OF THE POINTED (PNT) DOMAIN FROM THE TRANSCRITION FACTOR ERG
Descriptor:Transcriptional regulator ERG
Authors:Mackereth, C.D., Schaerpf, M., Gentile, L.N., MacIntosh, S.E., Slupsky, C.M., McIntosh, L.P.
Deposit date:2004-03-30
Release date:2004-09-21
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Diversity in Structure and Function of the Ets Family PNT Domains.
J.Mol.Biol., 342, 2004
2HF5
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THE STRUCTURE AND FUNCTION OF A NOVEL TWO-SITE CALCIUM-BINDING FRAGMENT OF CALMODULIN
Descriptor:Calmodulin, CALCIUM ION
Authors:Lakowski, T.M., Lee, G.M., Reid, R.E., McIntosh, L.P.
Deposit date:2006-06-23
Release date:2007-05-01
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Calcium-induced folding of a fragment of calmodulin composed of EF-hands 2 and 3
Protein Sci., 16, 2007
2JUO
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GABPA OST DOMAIN
Descriptor:GA-binding protein alpha chain
Authors:Kang, H., Nelson, M.L., Mackereth, C.D., Schaerpf, M., Graves, B.J., McIntosh, L.P.
Deposit date:2007-08-31
Release date:2008-04-08
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Identification and structural characterization of a CBP/p300-binding domain from the ETS family transcription factor GABP alpha
J.Mol.Biol., 377, 2008
2JUY
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NMR ENSEMBLE OF NEOPETROSIAMIDE A
Descriptor:Neopetrosiamide A
Authors:Austin, P., Williams, D.E., Heller, M., McIntosh, L.P., Andersen, R.J., Roberge, M., Roskelley, C.D.
Deposit date:2007-09-05
Release date:2008-08-26
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:NMR ensemble of Neopetrosiamide A
To be Published
2JW1
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STRUCTURAL CHARACTERIZATION OF THE TYPE III PILOTIN-SECRETIN INTERACTION IN SHIGELLA FLEXNERI BY NMR SPECTROSCOPY
Descriptor:Lipoprotein mxiM, Outer membrane protein mxiD
Authors:Okon, M.S., Lario, P.I., Creagh, L., Jung, Y.M.T., Maurelli, A.T., Strynadka, N.C.J., McIntosh, L.P.
Deposit date:2007-10-02
Release date:2008-09-02
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structural Characterization of the Type-III Pilot-Secretin Complex from Shigella flexneri
Structure, 16, 2008
2KMD
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RAS SIGNALING REQUIRES DYNAMIC PROPERTIES OF ETS1 FOR PHOSPHORYLATION-ENHANCED BINDING TO CO-ACTIVATOR CBP
Descriptor:Protein C-ets-1
Authors:Nelson, M.L., Kang, H., Lee, G.M., Blaszczak, A.G., Lau, D.K.W., McIntosh, L.P., Graves, B.J.
Deposit date:2009-07-27
Release date:2010-05-05
Last modified:2012-03-21
Method:SOLUTION NMR
Cite:Ras signaling requires dynamic properties of Ets1 for phosphorylation-enhanced binding to coactivator CBP.
Proc.Natl.Acad.Sci.USA, 107, 2010