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1QFH
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BU of 1qfh by Molmil
DIMERIZATION OF GELATION FACTOR FROM DICTYOSTELIUM DISCOIDEUM: CRYSTAL STRUCTURE OF ROD DOMAINS 5 AND 6
Descriptor: PROTEIN (GELATION FACTOR)
Authors:Mccoy, A.J, Fucini, P, Noegel, A.A, Stewart, M.
Deposit date:1999-04-11
Release date:1999-04-16
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural basis for dimerization of the Dictyostelium gelation factor (ABP120) rod.
Nat.Struct.Biol., 6, 1999
1E03
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BU of 1e03 by Molmil
PLASMA ALPHA ANTITHROMBIN-III AND PENTASACCHARIDE
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3,4-di-O-methyl-2,6-di-O-sulfo-alpha-D-glucopyranose-(1-4)-2,3-di-O-methyl-beta-D-glucopyranuronic acid-(1-4)-2,3,6-tri-O-sulfo-alpha-D-glucopyranose-(1-4)-3-O-methyl-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-methyl 2,3,6-tri-O-sulfo-alpha-D-glucopyranoside, ...
Authors:McCoy, A.J, Jin, L, Abrahams, J.-P, Skinner, R, Carrell, R.W.
Deposit date:2000-03-09
Release date:2000-06-02
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structure of Beta-Antithrombin and the Effect of Glycosylation on Antithrombin'S Heparin Affinity and Activity.
J.Mol.Biol., 326, 2003
1E05
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BU of 1e05 by Molmil
PLASMA ALPHA ANTITHROMBIN-III
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ANTITHROMBIN-III, ...
Authors:McCoy, A.J, Skinner, R, Abrahams, J.-P, Pei, X.Y, Carrell, R.W.
Deposit date:2000-03-09
Release date:2000-06-02
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.62 Å)
Cite:Structure of Beta-Antithrombin and the Effect of Glycosylation on Antithrombin'S Heparin Affinity and Activity.
J.Mol.Biol., 326, 2003
1E04
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BU of 1e04 by Molmil
PLASMA BETA ANTITHROMBIN-III
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ANTITHROMBIN-III, GLYCEROL, ...
Authors:Mccoy, A.J, Skinner, R, Abrahams, J.-P, Pei, X.Y, Carrell, R.W.
Deposit date:2000-03-09
Release date:2000-06-02
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of Beta-Antithrombin and the Effect of Glycosylation on Antithrombin'S Heparin Affinity and Activity.
J.Mol.Biol., 326, 2003
1DZH
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BU of 1dzh by Molmil
P14-FLUORESCEIN-N135Q-S380C-ANTITHROMBIN-III
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ANTITHROMBIN-III, ...
Authors:Mccoy, A.J, Huntington, J.A, Carrell, R.W.
Deposit date:2000-02-28
Release date:2000-05-26
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:The Conformational Activation of Antithrombin. A 2. 85-A Structure of a Fluorescein Derivative Reveals an Electrostatic Link between the Hinge and Heparin Binding Regions.
J.Biol.Chem., 275, 2000
1DZG
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BU of 1dzg by Molmil
N135Q-S380C-ANTITHROMBIN-III
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ANTITHROMBIN-III, ...
Authors:McCoy, A.J, Huntington, J.A, Carrell, R.W.
Deposit date:2000-02-28
Release date:2000-05-26
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The Conformational Activation of Antithrombin. A 2. 85-A Structure of a Fluorescein Derivative Reveals an Electrostatic Link between the Hinge and Heparin Binding Regions.
J.Biol.Chem., 275, 2000
1ASK
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BU of 1ask by Molmil
NUCLEAR TRANSPORT FACTOR 2 (NTF2) H66A MUTANT
Descriptor: NUCLEAR TRANSPORT FACTOR 2
Authors:Mccoy, A.J, Stewart, M.J.
Deposit date:1997-08-11
Release date:1998-01-28
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Nuclear protein import is decreased by engineered mutants of nuclear transport factor 2 (NTF2) that do not bind GDP-Ran.
J.Mol.Biol., 272, 1997
1AR0
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BU of 1ar0 by Molmil
NUCLEAR TRANSPORT FACTOR 2 (NTF2) E42K MUTANT
Descriptor: NUCLEAR TRANSPORT FACTOR 2
Authors:Mccoy, A.J, Stewart, M.J.
Deposit date:1997-08-08
Release date:1997-12-24
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Nuclear protein import is decreased by engineered mutants of nuclear transport factor 2 (NTF2) that do not bind GDP-Ran.
J.Mol.Biol., 272, 1997
5JP2
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BU of 5jp2 by Molmil
Fcho1 Mu homology domain (Danio Rerio) with bound Eps15 peptide
Descriptor: Epidermal growth factor receptor substrate 15, F-BAR domain only protein 1, ZINC ION
Authors:McCoy, A.J, Wrobel, A, Owen, D.J.
Deposit date:2016-05-03
Release date:2016-06-08
Last modified:2016-06-15
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Transient Fcho1/2Eps15/RAP-2 Nanoclusters Prime the AP-2 Clathrin Adaptor for Cargo Binding.
Dev.Cell, 37, 2016
6Z32
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BU of 6z32 by Molmil
Human cation-independent mannose 6-phosphate/IGF2 receptor domains 7-11
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Cation-independent mannose-6-phosphate receptor, SULFATE ION, ...
Authors:Bochel, A.J, Williams, C, McCoy, A.J, Hoppe, H, Winter, A.J, Nicholls, R.D, Harlos, K, Jones, Y.E, Berger, I, Hassan, B, Crump, M.P.
Deposit date:2020-05-19
Release date:2020-08-19
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.47 Å)
Cite:Structure of the Human Cation-Independent Mannose 6-Phosphate/IGF2 Receptor Domains 7-11 Uncovers the Mannose 6-Phosphate Binding Site of Domain 9.
Structure, 28, 2020
1NMC
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BU of 1nmc by Molmil
COMPLEX BETWEEN NC10 ANTI-INFLUENZA VIRUS NEURAMINIDASE SINGLE CHAIN ANTIBODY WITH A 15 RESIDUE LINKER AND INFLUENZA VIRUS NEURAMINIDASE
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, NEURAMINIDASE, ...
Authors:Malby, R.L, Mccoy, A.J, Kortt, A.A, Hudson, P.J, Colman, P.M.
Deposit date:1997-12-21
Release date:1998-09-23
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Three-dimensional structures of single-chain Fv-neuraminidase complexes.
J.Mol.Biol., 279, 1998
1QG2
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BU of 1qg2 by Molmil
CANINE GDP-RAN R76E MUTANT
Descriptor: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PROTEIN (RAN)
Authors:Kent, H.M, Moore, M.S, Quimby, B.B, Baker, A.M.E, McCoy, A.J, Murphy, G.A, Corbett, A.H, Stewart, M.
Deposit date:1999-04-20
Release date:1999-06-11
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Engineered mutants in the switch II loop of Ran define the contribution made by key residues to the interaction with nuclear transport factor 2 (NTF2) and the role of this interaction in nuclear protein import.
J.Mol.Biol., 289, 1999
1QG4
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BU of 1qg4 by Molmil
CANINE GDP-RAN F72Y MUTANT
Descriptor: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PROTEIN (RAN)
Authors:Kent, H.M, Moore, M.S, Quimby, B.B, Baker, A.M.E, McCoy, A.J, Murphy, G.A, Corbett, A.H, Stewart, M.
Deposit date:1999-04-20
Release date:1999-06-11
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Engineered mutants in the switch II loop of Ran define the contribution made by key residues to the interaction with nuclear transport factor 2 (NTF2) and the role of this interaction in nuclear protein import.
J.Mol.Biol., 289, 1999
4N3E
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BU of 4n3e by Molmil
Crystal structure of Hyp-1, a St John's wort PR-10 protein, in complex with 8-anilino-1-naphthalene sulfonate (ANS)
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 8-ANILINO-1-NAPHTHALENE SULFONATE, Phenolic oxidative coupling protein, ...
Authors:Sliwiak, J, Dauter, Z, Mccoy, A.J, Read, R.J, Jaskolski, M.
Deposit date:2013-10-07
Release date:2014-02-26
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.43 Å)
Cite:Likelihood-based molecular-replacement solution for a highly pathological crystal with tetartohedral twinning and sevenfold translational noncrystallographic symmetry.
Acta Crystallogr.,Sect.D, 70, 2014
1A14
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BU of 1a14 by Molmil
COMPLEX BETWEEN NC10 ANTI-INFLUENZA VIRUS NEURAMINIDASE SINGLE CHAIN ANTIBODY WITH A 5 RESIDUE LINKER AND INFLUENZA VIRUS NEURAMINIDASE
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, NC10 FV (HEAVY CHAIN), ...
Authors:Malby, R.L, Mccoy, A.J, Kortt, A.A, Hudson, P.J, Colman, P.M.
Deposit date:1997-12-21
Release date:1998-05-13
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Three-dimensional structures of single-chain Fv-neuraminidase complexes.
J.Mol.Biol., 279, 1998
1BYU
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BU of 1byu by Molmil
CANINE GDP-RAN
Descriptor: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PROTEIN (GTP-BINDING PROTEIN RAN)
Authors:Stewart, M, Kent, H.M, Mccoy, A.J.
Deposit date:1998-10-18
Release date:1998-12-02
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:The structure of the Q69L mutant of GDP-Ran shows a major conformational change in the switch II loop that accounts for its failure to bind nuclear transport factor 2 (NTF2).
J.Mol.Biol., 284, 1998
6QH7
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BU of 6qh7 by Molmil
AP2 clathrin adaptor mu2T156-phosphorylated core with two cargo peptides in open+ conformation
Descriptor: ADAPTOR-RELATED PROTEIN COMPLEX 2, MU 2 SUBUNIT, C-TERMINAL DOMAIN, ...
Authors:Wrobel, A.G, Owen, D.J, McCoy, A.J, Evans, P.R.
Deposit date:2019-01-15
Release date:2019-09-04
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Temporal Ordering in Endocytic Clathrin-Coated Vesicle Formation via AP2 Phosphorylation.
Dev.Cell, 50, 2019
4C9G
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BU of 4c9g by Molmil
Structure of yeast mitochondrial ADP/ATP carrier isoform 2 inhibited by carboxyatractyloside (C2221 crystal form)
Descriptor: ADP, ATP CARRIER PROTEIN 2, CARDIOLIPIN, ...
Authors:Ruprecht, J.J, Hellawell, A.M, Harding, M, Crichton, P.G, McCoy, A.J, Kunji, E.R.S.
Deposit date:2013-10-02
Release date:2014-01-22
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:Structures of Yeast Mitochondrial Adp/ATP Carriers Support a Domain-Based Alternating-Access Transport Mechanism
Proc.Natl.Acad.Sci.USA, 111, 2014
4C9Q
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BU of 4c9q by Molmil
Structure of yeast mitochondrial ADP/ATP carrier isoform 3 inhibited by carboxyatractyloside (P21 crystal form)
Descriptor: ADP, ATP CARRIER PROTEIN 3, CARDIOLIPIN, ...
Authors:Ruprecht, J.J, Hellawell, A.M, Harding, M, Crichton, P.G, McCoy, A.J, Kunji, E.R.S.
Deposit date:2013-10-02
Release date:2014-01-22
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structures of Yeast Mitochondrial Adp/ATP Carriers Support a Domain-Based Alternating-Access Transport Mechanism
Proc.Natl.Acad.Sci.USA, 111, 2014
4C9J
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BU of 4c9j by Molmil
Structure of yeast mitochondrial ADP/ATP carrier isoform 3 inhibited by carboxyatractyloside (P212121 crystal form)
Descriptor: ADP, ATP CARRIER PROTEIN 3, CARDIOLIPIN, ...
Authors:Ruprecht, J.J, Hellawell, A.M, Harding, M, Crichton, P.G, McCoy, A.J, Kunji, E.R.S.
Deposit date:2013-10-02
Release date:2014-01-22
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.397 Å)
Cite:Structures of Yeast Mitochondrial Adp/ATP Carriers Support a Domain-Based Alternating-Access Transport Mechanism
Proc.Natl.Acad.Sci.USA, 111, 2014
4C9H
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BU of 4c9h by Molmil
Structure of yeast mitochondrial ADP/ATP carrier isoform 2 inhibited by carboxyatractyloside (P212121 crystal form)
Descriptor: 5-CYCLOHEXYL-1-PENTYL-BETA-D-MALTOSIDE, ADP, ATP CARRIER PROTEIN 2, ...
Authors:Ruprecht, J.J, Hellawell, A.M, Harding, M, Crichton, P.G, McCoy, A.J, Kunji, E.R.S.
Deposit date:2013-10-02
Release date:2014-01-22
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structures of Yeast Mitochondrial Adp/ATP Carriers Support a Domain-Based Alternating-Access Transport Mechanism
Proc.Natl.Acad.Sci.USA, 111, 2014
4CYM
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BU of 4cym by Molmil
Complex of human VARP-ANKRD1 with Rab32-GppCp
Descriptor: ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 27, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, ...
Authors:Perez-Dorado, I, Schaefer, I.B, McCoy, A.J, Owen, D.J, Evans, P.R.
Deposit date:2014-04-13
Release date:2014-06-04
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Varp is Recruited on to Endosomes by Direct Interaction with Retromer, Where Together They Function in Export to the Cell Surface.
Dev.Cell, 29, 2014
4CZ2
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BU of 4cz2 by Molmil
Complex of human VARP-ANKRD1 with Rab32-GppCp. Selenomet derivative.
Descriptor: ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 27, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, ...
Authors:Perez-Dorado, I, Schaefer, I.B, McCoy, A.J, Owen, D.J, Evans, P.R.
Deposit date:2014-04-16
Release date:2014-06-04
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.97 Å)
Cite:Varp is Recruited on to Endosomes by Direct Interaction with Retromer, Where Together They Function in Export to the Cell Surface.
Dev.Cell, 29, 2014
3RAN
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BU of 3ran by Molmil
CANINE GDP-RAN Q69L MUTANT
Descriptor: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PROTEIN (GTP-BINDING NUCLEAR PROTEIN RAN)
Authors:Stewart, M, Kent, H.M, Mccoy, A.J.
Deposit date:1998-10-19
Release date:1998-12-02
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:The structure of the Q69L mutant of GDP-Ran shows a major conformational change in the switch II loop that accounts for its failure to bind nuclear transport factor 2 (NTF2).
J.Mol.Biol., 284, 1998
2QYW
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BU of 2qyw by Molmil
Crystal structure of mouse vti1b Habc domain
Descriptor: Vesicle transport through interaction with t-SNAREs 1B homolog
Authors:Miller, S.E, Collins, B.M, McCoy, A.J, Robinson, M.S, Owen, D.J.
Deposit date:2007-08-15
Release date:2007-11-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:A SNARE-adaptor interaction is a new mode of cargo recognition in clathrin-coated vesicles.
Nature, 450, 2007

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