Author results

1QFH
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DIMERIZATION OF GELATION FACTOR FROM DICTYOSTELIUM DISCOIDEUM: CRYSTAL STRUCTURE OF ROD DOMAINS 5 AND 6
Descriptor:PROTEIN (GELATION FACTOR)
Authors:Mccoy, A.J., Fucini, P., Noegel, A.A., Stewart, M.
Deposit date:1999-04-11
Release date:1999-04-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural basis for dimerization of the Dictyostelium gelation factor (ABP120) rod.
Nat.Struct.Biol., 6, 1999
1E03
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PLASMA ALPHA ANTITHROMBIN-III AND PENTASACCHARIDE
Descriptor:ANTITHROMBIN-III, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:McCoy, A.J., Jin, L., Abrahams, J.-P., Skinner, R., Carrell, R.W.
Deposit date:2000-03-09
Release date:2000-06-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structure of Beta-Antithrombin and the Effect of Glycosylation on Antithrombin'S Heparin Affinity and Activity.
J.Mol.Biol., 326, 2003
1E04
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PLASMA BETA ANTITHROMBIN-III
Descriptor:ANTITHROMBIN-III, N-ACETYL-D-GLUCOSAMINE, ALPHA-D-MANNOSE, ...
Authors:Mccoy, A.J., Skinner, R., Abrahams, J.-P., Pei, X.Y., Carrell, R.W.
Deposit date:2000-03-09
Release date:2000-06-02
Last modified:2011-08-17
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of Beta-Antithrombin and the Effect of Glycosylation on Antithrombin'S Heparin Affinity and Activity.
J.Mol.Biol., 326, 2003
1E05
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PLASMA ALPHA ANTITHROMBIN-III
Descriptor:ANTITHROMBIN-III, N-ACETYL-D-GLUCOSAMINE, ALPHA-D-MANNOSE, ...
Authors:McCoy, A.J., Skinner, R., Abrahams, J.-P., Pei, X.Y., Carrell, R.W.
Deposit date:2000-03-09
Release date:2000-06-02
Last modified:2011-11-09
Method:X-RAY DIFFRACTION (2.62 Å)
Cite:Structure of Beta-Antithrombin and the Effect of Glycosylation on Antithrombin'S Heparin Affinity and Activity.
J.Mol.Biol., 326, 2003
1AR0
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NUCLEAR TRANSPORT FACTOR 2 (NTF2) E42K MUTANT
Descriptor:NUCLEAR TRANSPORT FACTOR 2
Authors:Mccoy, A.J., Stewart, M.J.
Deposit date:1997-08-08
Release date:1997-12-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Nuclear protein import is decreased by engineered mutants of nuclear transport factor 2 (NTF2) that do not bind GDP-Ran.
J.Mol.Biol., 272, 1997
1ASK
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NUCLEAR TRANSPORT FACTOR 2 (NTF2) H66A MUTANT
Descriptor:NUCLEAR TRANSPORT FACTOR 2
Authors:Mccoy, A.J., Stewart, M.J.
Deposit date:1997-08-11
Release date:1998-01-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Nuclear protein import is decreased by engineered mutants of nuclear transport factor 2 (NTF2) that do not bind GDP-Ran.
J.Mol.Biol., 272, 1997
1DZG
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N135Q-S380C-ANTITHROMBIN-III
Descriptor:ANTITHROMBIN-III, N-ACETYL-D-GLUCOSAMINE, GLYCEROL
Authors:McCoy, A.J., Huntington, J.A., Carrell, R.W.
Deposit date:2000-02-28
Release date:2000-05-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The Conformational Activation of Antithrombin. A 2. 85-A Structure of a Fluorescein Derivative Reveals an Electrostatic Link between the Hinge and Heparin Binding Regions.
J.Biol.Chem., 275, 2000
1DZH
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P14-FLUORESCEIN-N135Q-S380C-ANTITHROMBIN-III
Descriptor:ANTITHROMBIN-III, N-ACETYL-D-GLUCOSAMINE, GLYCEROL, ...
Authors:Mccoy, A.J., Huntington, J.A., Carrell, R.W.
Deposit date:2000-02-28
Release date:2000-05-26
Last modified:2017-07-12
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:The Conformational Activation of Antithrombin. A 2. 85-A Structure of a Fluorescein Derivative Reveals an Electrostatic Link between the Hinge and Heparin Binding Regions.
J.Biol.Chem., 275, 2000
5JP2
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FCHO1 MU HOMOLOGY DOMAIN (DANIO RERIO) WITH BOUND EPS15 PEPTIDE
Descriptor:Epidermal growth factor receptor substrate 15, F-BAR domain only protein 1, ZINC ION
Authors:McCoy, A.J., Wrobel, A., Owen, D.J.
Deposit date:2016-05-03
Release date:2016-06-08
Last modified:2016-06-15
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Transient Fcho1/2Eps15/RAP-2 Nanoclusters Prime the AP-2 Clathrin Adaptor for Cargo Binding.
Dev.Cell, 37, 2016
1A14
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COMPLEX BETWEEN NC10 ANTI-INFLUENZA VIRUS NEURAMINIDASE SINGLE CHAIN ANTIBODY WITH A 5 RESIDUE LINKER AND INFLUENZA VIRUS NEURAMINIDASE
Descriptor:NEURAMINIDASE, NC10 FV (HEAVY CHAIN), NC10 FV (LIGHT CHAIN), ...
Authors:Malby, R.L., Mccoy, A.J., Kortt, A.A., Hudson, P.J., Colman, P.M.
Deposit date:1997-12-21
Release date:1998-05-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Three-dimensional structures of single-chain Fv-neuraminidase complexes.
J.Mol.Biol., 279, 1998
1A2K
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GDPRAN-NTF2 COMPLEX
Descriptor:NUCLEAR TRANSPORT FACTOR 2, RAN, MAGNESIUM ION, ...
Authors:Stewart, M., Kent, H.M., Mccoy, A.J.
Deposit date:1998-01-06
Release date:1998-04-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis for molecular recognition between nuclear transport factor 2 (NTF2) and the GDP-bound form of the Ras-family GTPase Ran.
J.Mol.Biol., 277, 1998
1BYU
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CANINE GDP-RAN
Descriptor:PROTEIN (GTP-BINDING PROTEIN RAN), MAGNESIUM ION, GUANOSINE-5'-DIPHOSPHATE
Authors:Stewart, M., Kent, H.M., Mccoy, A.J.
Deposit date:1998-10-18
Release date:1998-12-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:The structure of the Q69L mutant of GDP-Ran shows a major conformational change in the switch II loop that accounts for its failure to bind nuclear transport factor 2 (NTF2).
J.Mol.Biol., 284, 1998
1NMC
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COMPLEX BETWEEN NC10 ANTI-INFLUENZA VIRUS NEURAMINIDASE SINGLE CHAIN ANTIBODY WITH A 15 RESIDUE LINKER AND INFLUENZA VIRUS NEURAMINIDASE
Descriptor:NEURAMINIDASE, SINGLE CHAIN ANTIBODY, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Malby, R.L., Mccoy, A.J., Kortt, A.A., Hudson, P.J., Colman, P.M.
Deposit date:1997-12-21
Release date:1998-09-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Three-dimensional structures of single-chain Fv-neuraminidase complexes.
J.Mol.Biol., 279, 1998
1QG2
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CANINE GDP-RAN R76E MUTANT
Descriptor:PROTEIN (RAN), MAGNESIUM ION, GUANOSINE-5'-DIPHOSPHATE
Authors:Kent, H.M., Moore, M.S., Quimby, B.B., Baker, A.M.E., McCoy, A.J., Murphy, G.A., Corbett, A.H., Stewart, M.
Deposit date:1999-04-20
Release date:1999-06-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Engineered mutants in the switch II loop of Ran define the contribution made by key residues to the interaction with nuclear transport factor 2 (NTF2) and the role of this interaction in nuclear protein import.
J.Mol.Biol., 289, 1999
1QG4
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CANINE GDP-RAN F72Y MUTANT
Descriptor:PROTEIN (RAN), MAGNESIUM ION, GUANOSINE-5'-DIPHOSPHATE
Authors:Kent, H.M., Moore, M.S., Quimby, B.B., Baker, A.M.E., McCoy, A.J., Murphy, G.A., Corbett, A.H., Stewart, M.
Deposit date:1999-04-20
Release date:1999-06-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Engineered mutants in the switch II loop of Ran define the contribution made by key residues to the interaction with nuclear transport factor 2 (NTF2) and the role of this interaction in nuclear protein import.
J.Mol.Biol., 289, 1999
2JKR
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AP2 CLATHRIN ADAPTOR CORE WITH DILEUCINE PEPTIDE RM(PHOSPHOS)QIKRLLSE
Descriptor:AP-2 COMPLEX SUBUNIT ALPHA-2, AP-2 COMPLEX SUBUNIT BETA-1, AP-2 COMPLEX SUBUNIT SIGMA-1, ...
Authors:Owen, D.J., McCoy, A.J., Kelly, B.T., Evans, P.R.
Deposit date:2008-08-29
Release date:2008-10-28
Last modified:2012-06-20
Method:X-RAY DIFFRACTION (2.98 Å)
Cite:A Structural Explanation for the Binding of Endocytic Dileucine Motifs by the Ap2 Complex.
Nature, 456, 2008
2JKT
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AP2 CLATHRIN ADAPTOR CORE WITH CD4 DILEUCINE PEPTIDE RM(PHOSPHOS) EIKRLLSE Q TO E MUTANT
Descriptor:AP-2 COMPLEX SUBUNIT ALPHA-2, AP-2 COMPLEX SUBUNIT BETA-1, AP-2 COMPLEX SUBUNIT SIGMA-1, ...
Authors:Owen, D.J., McCoy, A.J., Kelly, B.T., Evans, P.R.
Deposit date:2008-08-29
Release date:2008-10-28
Last modified:2012-06-20
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:A Structural Explanation for the Binding of Endocytic Dileucine Motifs by the Ap2 Complex.
Nature, 456, 2008
2MSP
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MAJOR SPERM PROTEIN, BETA ISOFORM, ENGINEERED C59S/T90C MUTANT, PUTATIVE SUBFILAMENT STRUCTURE, PH 8.5
Descriptor:MAJOR SPERM PROTEIN
Authors:Bullock, T.L., Mccoy, A.J., Stewart, M.
Deposit date:1997-12-19
Release date:1998-04-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structural basis for amoeboid motility in nematode sperm.
Nat.Struct.Biol., 5, 1998
2QY7
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CRYSTAL STRUCTURE OF HUMAN EPSINR ENTH DOMAIN
Descriptor:Clathrin interactor 1
Authors:Miller, S.E., Collins, B.M., McCoy, A.J., Robinson, M.S., Owen, D.J.
Deposit date:2007-08-13
Release date:2007-11-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:A SNARE-adaptor interaction is a new mode of cargo recognition in clathrin-coated vesicles.
Nature, 450, 2007
2QYW
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CRYSTAL STRUCTURE OF MOUSE VTI1B HABC DOMAIN
Descriptor:Vesicle transport through interaction with t-SNAREs 1B homolog
Authors:Miller, S.E., Collins, B.M., McCoy, A.J., Robinson, M.S., Owen, D.J.
Deposit date:2007-08-15
Release date:2007-11-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:A SNARE-adaptor interaction is a new mode of cargo recognition in clathrin-coated vesicles.
Nature, 450, 2007
2V8S
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VTI1B HABC DOMAIN - EPSINR ENTH DOMAIN COMPLEX
Descriptor:CLATHRIN INTERACTOR 1, VESICLE TRANSPORT THROUGH INTERACTION WITH T-SNARES HOMOLOG 1B, GLYCEROL
Authors:Owen, D.J., McCoy, A.J., Collins, B.M., Miller, S.E.
Deposit date:2007-08-14
Release date:2007-11-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.22 Å)
Cite:A Snare-Adaptor Interaction is a New Mode of Cargo Recognition in Clathrin Coated Vesicles
Nature, 450, 2007
2VGL
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AP2 CLATHRIN ADAPTOR CORE
Descriptor:ADAPTOR PROTEIN COMPLEX AP-2, ALPHA 2 SUBUNIT, AP-2 COMPLEX SUBUNIT BETA-1, ...
Authors:Owen, D.J., Collins, B.M., McCoy, A.J., Evans, P.R.
Deposit date:2007-11-14
Release date:2007-12-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Molecular Architecture and Functional Model of the Endocytic Ap2 Complex
Cell(Cambridge,Mass.), 109, 2002
2XA7
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AP2 CLATHRIN ADAPTOR CORE IN ACTIVE COMPLEX WITH CARGO PEPTIDES
Descriptor:ADAPTOR-RELATED PROTEIN COMPLEX 2, ALPHA 2 SUBUNIT, AP-2 COMPLEX SUBUNIT BETA, ...
Authors:Jackson, L.P., Kelly, B.T., McCoy, A.J., Evans, P.R., Owen, D.J.
Deposit date:2010-03-29
Release date:2010-07-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:A Large Scale Conformational Change Couples Membrane Recruitment to Cargo Binding in the Ap2 Clathrin Adaptor Complex
Cell(Cambridge,Mass.), 141, 2010
3RAN
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CANINE GDP-RAN Q69L MUTANT
Descriptor:PROTEIN (GTP-BINDING NUCLEAR PROTEIN RAN), MAGNESIUM ION, GUANOSINE-5'-DIPHOSPHATE
Authors:Stewart, M., Kent, H.M., Mccoy, A.J.
Deposit date:1998-10-19
Release date:1998-12-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:The structure of the Q69L mutant of GDP-Ran shows a major conformational change in the switch II loop that accounts for its failure to bind nuclear transport factor 2 (NTF2).
J.Mol.Biol., 284, 1998
4C9G
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STRUCTURE OF YEAST MITOCHONDRIAL ADP/ATP CARRIER ISOFORM 2 INHIBITED BY CARBOXYATRACTYLOSIDE (C2221 CRYSTAL FORM)
Descriptor:ADP, ATP CARRIER PROTEIN 2, Carboxyatractyloside, ...
Authors:Ruprecht, J.J., Hellawell, A.M., Harding, M., Crichton, P.G., McCoy, A.J., Kunji, E.R.S.
Deposit date:2013-10-02
Release date:2014-01-22
Last modified:2014-02-12
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:Structures of Yeast Mitochondrial Adp/ATP Carriers Support a Domain-Based Alternating-Access Transport Mechanism
Proc.Natl.Acad.Sci.USA, 111, 2014