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Crystal Structure of the GluR5 Ligand Binding Core Dimer with Glutamate At 2.1 Angstroms Resolution
Descriptor:	GLUTAMATE RECEPTOR, IONOTROPIC KAINATE 1, GLUTAMIC ACID, ...
Authors:	Mayer, M.L.
Deposit date:	2005-11-18
Release date:	2006-04-04
Last modified:	2023-08-23
Method:	X-RAY DIFFRACTION (2.11 Å)
Cite:	Crystal structures of the kainate receptor GluR5 ligand binding core dimer with novel GluR5-selective antagonists. J.Neurosci., 26, 2006

2F34

Crystal Structure of the GluR5 Ligand Binding Core Dimer with UBP310 At 1.74 Angstroms Resolution
Descriptor:	(S)-1-(2-AMINO-2-CARBOXYETHYL)-3(2-CARBOXYTHIOPHENE-3-YL-METHYL)-5-METHYLPYRIMIDINE-2,4-DIONE, CHLORIDE ION, GLUTAMATE RECEPTOR, ...
Authors:	Mayer, M.L.
Deposit date:	2005-11-18
Release date:	2006-04-04
Last modified:	2023-08-23
Method:	X-RAY DIFFRACTION (1.74 Å)
Cite:	Crystal structures of the kainate receptor GluR5 ligand binding core dimer with novel GluR5-selective antagonists. J.Neurosci., 26, 2006

2F35

Crystal Structure of the GluR5 Ligand Binding Core with UBP302 At 1.87 Angstroms Resolution
Descriptor:	(S)-1-(2-AMINO-2-CARBOXYETHYL)-3-(2-CARBOXYBENZYL)PYRIMIDINE-2,4-DIONE, CHLORIDE ION, GLUTAMATE RECEPTOR, ...
Authors:	Mayer, M.L.
Deposit date:	2005-11-18
Release date:	2006-04-04
Last modified:	2024-04-03
Method:	X-RAY DIFFRACTION (1.87 Å)
Cite:	Crystal structures of the kainate receptor GluR5 ligand binding core dimer with novel GluR5-selective antagonists. J.Neurosci., 26, 2006

1TXF

CRYSTAL STRUCTURE OF THE GLUR5 LIGAND BINDING CORE IN COMPLEX WITH GLUTAMATE AT 2.1 ANGSTROM RESOLUTION
Descriptor:	GLUTAMIC ACID, Glutamate receptor, ionotropic kainate 1
Authors:	Mayer, M.L.
Deposit date:	2004-07-04
Release date:	2005-02-08
Last modified:	2023-08-23
Method:	X-RAY DIFFRACTION (2.1 Å)
Cite:	Crystal structures of the GluR5 and GluR6 ligand binding cores: Molecular mechanisms underlying kainate receptor selectivity Neuron, 45, 2005

1TT1

CRYSTAL STRUCTURE OF THE GLUR6 LIGAND BINDING CORE IN COMPLEX WITH KAINATE 1.93 A RESOLUTION
Descriptor:	3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE, Glutamate receptor, ionotropic kainate 2
Authors:	Mayer, M.L.
Deposit date:	2004-06-21
Release date:	2005-02-08
Last modified:	2023-08-23
Method:	X-RAY DIFFRACTION (1.93 Å)
Cite:	Crystal structures of the GluR5 and GluR6 ligand binding cores: Molecular mechanisms underlying kainate receptor selectivity Neuron, 45, 2005

1IIT

GLUR0 LIGAND BINDING CORE COMPLEX WITH L-SERINE
Descriptor:	SERINE, Slr1257 protein
Authors:	Mayer, M.L, Olson, R, Gouaux, E.
Deposit date:	2001-04-24
Release date:	2001-09-19
Last modified:	2024-02-07
Method:	X-RAY DIFFRACTION (1.9 Å)
Cite:	Mechanisms for ligand binding to GluR0 ion channels: crystal structures of the glutamate and serine complexes and a closed apo state. J.Mol.Biol., 311, 2001

1II5

CRYSTAL STRUCTURE OF THE GLUR0 LIGAND BINDING CORE COMPLEX WITH L-GLUTAMATE
Descriptor:	GLUTAMIC ACID, Slr1257 protein
Authors:	Mayer, M.L, Olson, R, Gouaux, E.
Deposit date:	2001-04-20
Release date:	2001-09-19
Last modified:	2024-02-07
Method:	X-RAY DIFFRACTION (1.6 Å)
Cite:	Mechanisms for ligand binding to GluR0 ion channels: crystal structures of the glutamate and serine complexes and a closed apo state. J.Mol.Biol., 311, 2001

1IIW

GLUR0 LIGAND BINDING CORE: CLOSED-CLEFT LIGAND-FREE STRUCTURE
Descriptor:	Slr1257 protein
Authors:	Mayer, M.L, Olson, R, Gouaux, E.
Deposit date:	2001-04-24
Release date:	2001-09-19
Last modified:	2024-02-07
Method:	X-RAY DIFFRACTION (1.9 Å)
Cite:	Mechanisms for ligand binding to GluR0 ion channels: crystal structures of the glutamate and serine complexes and a closed apo state. J.Mol.Biol., 311, 2001

1S50

X-ray structure of the GluR6 ligand binding core (S1S2A) in complex with glutamate at 1.65 A resolution
Descriptor:	GLUTAMIC ACID, Glutamate Receptor 6
Authors:	Mayer, M.L.
Deposit date:	2004-01-19
Release date:	2005-02-08
Last modified:	2023-08-23
Method:	X-RAY DIFFRACTION (1.65 Å)
Cite:	Crystal structures of the GluR5 and GluR6 ligand binding cores: Molecular mechanisms underlying kainate receptor selectivity Neuron, 45, 2005

1SD3

Crystal structure of the GLUR6 ligand binding core in complex with 2S,4R-4-methylglutamate at 1.8 Angstrom resolution
Descriptor:	2S,4R-4-METHYLGLUTAMATE, Glutamate receptor, ionotropic kainate 2
Authors:	Mayer, M.L.
Deposit date:	2004-02-12
Release date:	2005-02-15
Last modified:	2023-10-25
Method:	X-RAY DIFFRACTION (1.8 Å)
Cite:	Crystal structures of the GluR5 and GluR6 ligand binding cores: molecular mechanisms underlying kainate receptor selectivity. Neuron, 45, 2005

1S9T

Crystal structure of the GLUR6 ligand binding core in complex with quisqualate at 1.8A resolution
Descriptor:	(S)-2-AMINO-3-(3,5-DIOXO-[1,2,4]OXADIAZOLIDIN-2-YL)-PROPIONIC ACID, CHLORIDE ION, Glutamate receptor, ...
Authors:	Mayer, M.L.
Deposit date:	2004-02-05
Release date:	2005-02-08
Last modified:	2023-10-25
Method:	X-RAY DIFFRACTION (1.8 Å)
Cite:	Crystal structures of the GluR5 and GluR6 ligand binding cores: molecular mechanisms underlying kainate receptor selectivity. Neuron, 45, 2005

1S7Y

Crystal structure of the GluR6 ligand binding core in complex with glutamate at 1.75 A resolution orthorhombic form
Descriptor:	GLUTAMIC ACID, Glutamate receptor, ionotropic kainate 2 precursor
Authors:	Mayer, M.L.
Deposit date:	2004-01-30
Release date:	2005-02-08
Last modified:	2024-02-14
Method:	X-RAY DIFFRACTION (1.75 Å)
Cite:	Crystal structures of the GluR5 and GluR6 ligand binding cores: Molecular mechanisms underlying kainate receptor selectivity Neuron, 45, 2005

3C33

Crystal structure of GluR5 ligand-binding core in complex with potassium at 1.78 Angstrom resolution
Descriptor:	3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE, CHLORIDE ION, GLUTAMATE RECEPTOR, ...
Authors:	Mayer, M.L.
Deposit date:	2008-01-27
Release date:	2008-06-17
Last modified:	2023-08-30
Method:	X-RAY DIFFRACTION (1.72 Å)
Cite:	Molecular basis of kainate receptor modulation by sodium. Neuron, 58, 2008

3C36

Crystal structure of GluR5 ligand-binding core in complex with ammonium ions at 1.68 Angstrom resolution
Descriptor:	3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE, AMMONIUM ION, CHLORIDE ION, ...
Authors:	Mayer, M.L.
Deposit date:	2008-01-27
Release date:	2008-06-17
Last modified:	2023-08-30
Method:	X-RAY DIFFRACTION (1.68 Å)
Cite:	Molecular basis of kainate receptor modulation by sodium. Neuron, 58, 2008

3C34

Crystal structure of GluR5 ligand-binding core in complex with rubidium at 1.82 Angstrom resolution
Descriptor:	3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE, CHLORIDE ION, GLUTAMATE RECEPTOR, ...
Authors:	Mayer, M.L.
Deposit date:	2008-01-27
Release date:	2008-06-17
Last modified:	2023-08-30
Method:	X-RAY DIFFRACTION (1.82 Å)
Cite:	Molecular basis of kainate receptor modulation by sodium. Neuron, 58, 2008

3C35

Crystal structure of GluR5 ligand-binding core in complex with cesium at 1.97 Angstrom resolution
Descriptor:	3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE, CESIUM ION, CHLORIDE ION, ...
Authors:	Mayer, M.L.
Deposit date:	2008-01-27
Release date:	2008-06-17
Last modified:	2023-08-30
Method:	X-RAY DIFFRACTION (1.97 Å)
Cite:	Molecular basis of kainate receptor modulation by sodium. Neuron, 58, 2008

3C32

Crystal structure of GluR5 ligand-binding core in complex with sodium at 1.72 Angstrom resolution
Descriptor:	3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE, CHLORIDE ION, GLUTAMATE RECEPTOR, ...
Authors:	Mayer, M.L.
Deposit date:	2008-01-27
Release date:	2008-06-17
Last modified:	2023-08-30
Method:	X-RAY DIFFRACTION (1.72 Å)
Cite:	Molecular basis of kainate receptor modulation by sodium. Neuron, 58, 2008

3C31

Crystal structure of GluR5 ligand-binding core in complex with lithium at 1.49 Angstrom resolution
Descriptor:	3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE, CHLORIDE ION, GLUTAMATE RECEPTOR, ...
Authors:	Mayer, M.L.
Deposit date:	2008-01-27
Release date:	2008-06-17
Last modified:	2023-08-30
Method:	X-RAY DIFFRACTION (1.49 Å)
Cite:	Molecular basis of kainate receptor modulation by sodium. Neuron, 58, 2008

2GFE

Crystal structure of the GluR2 A476E S673D Ligand Binding Core Mutant at 1.54 Angstroms Resolution
Descriptor:	GLUTAMIC ACID, Glutamate receptor 2, ZINC ION
Authors:	Mayer, M.L.
Deposit date:	2006-03-21
Release date:	2006-08-22
Last modified:	2023-08-30
Method:	X-RAY DIFFRACTION (1.54 Å)
Cite:	Interdomain interactions in AMPA and kainate receptors regulate affinity for glutamate. J.Neurosci., 26, 2006

2I0B

Crystal structure of the GluR6 ligand binding core ELKQ mutant dimer at 1.96 Angstroms Resolution
Descriptor:	GLUTAMIC ACID, Glutamate receptor, ionotropic kainate 2, ...
Authors:	Mayer, M.L.
Deposit date:	2006-08-10
Release date:	2006-11-21
Last modified:	2024-04-03
Method:	X-RAY DIFFRACTION (1.96 Å)
Cite:	Conformational restriction blocks glutamate receptor desensitization. Nat.Struct.Mol.Biol., 13, 2006

2I0C

Crystal structure of the GluR6 ligand binding core dimer crosslinked by disulfide bonds between Y490C and L752C at 2.25 Angstroms Resolution
Descriptor:	GLUTAMIC ACID, Glutamate receptor, ionotropic kainate 2
Authors:	Mayer, M.L.
Deposit date:	2006-08-10
Release date:	2006-11-21
Last modified:	2024-04-03
Method:	X-RAY DIFFRACTION (2.25 Å)
Cite:	Conformational restriction blocks glutamate receptor desensitization. Nat.Struct.Mol.Biol., 13, 2006

5CMB

Mnemiopsis leidyi ML032222a iGluR LBD R703K mutant glycine complex
Descriptor:	GLYCINE, MAGNESIUM ION, ML032222a iGluR, ...
Authors:	Mayer, M.L, Thomas, A.
Deposit date:	2015-07-16
Release date:	2016-07-20
Last modified:	2023-09-27
Method:	X-RAY DIFFRACTION (1.34 Å)
Cite:	Molecular lock regulates binding of glycine to a primitive NMDA receptor. Proc.Natl.Acad.Sci.USA, 113, 2016

5CMC

Mnemiopsis leidyi ML032222a iGluR LBD E423S mutant glycine complex
Descriptor:	GLYCINE, MAGNESIUM ION, ML032222a iGluR, ...
Authors:	Mayer, M.L, Thomas, A.
Deposit date:	2015-07-16
Release date:	2016-07-20
Last modified:	2023-09-27
Method:	X-RAY DIFFRACTION (1.28 Å)
Cite:	Molecular lock regulates binding of glycine to a primitive NMDA receptor. Proc.Natl.Acad.Sci.USA, 113, 2016

2OJT

Structure and mechanism of kainate receptor modulation by anions
Descriptor:	(S)-1-(2-AMINO-2-CARBOXYETHYL)-3(2-CARBOXYTHIOPHENE-3-YL-METHYL)-5-METHYLPYRIMIDINE-2,4-DIONE, BROMIDE ION, Glutamate receptor, ...
Authors:	Mayer, M.L.
Deposit date:	2007-01-14
Release date:	2007-04-03
Last modified:	2023-08-30
Method:	X-RAY DIFFRACTION (1.95 Å)
Cite:	Structure and mechanism of kainate receptor modulation by anions. Neuron, 53, 2007

4UQ6

Electron density map of GluA2em in complex with LY451646 and glutamate
Descriptor:	GLUTAMATE RECEPTOR 2, GLUTAMIC ACID
Authors:	Meyerson, J.R, Kumar, J, Chittori, S, Rao, P, Pierson, J, Bartesaghi, A, Mayer, M.L, Subramaniam, S.
Deposit date:	2014-06-20
Release date:	2014-08-13
Last modified:	2017-08-02
Method:	ELECTRON MICROSCOPY (12.8 Å)
Cite:	Structural Mechanism of Glutamate Receptor Activation and Desensitization Nature, 514, 2014

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