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Crystal structure of TrmD from Pseudomonas aeruginosa in complex with active-site inhibitor
Descriptor:	N-{(3S)-1-[3-(pyridin-4-yl)-1H-pyrazol-5-yl]piperidin-3-yl}-1H-indole-2-carboxamide, S-ADENOSYLMETHIONINE, tRNA (guanine-N(1)-)-methyltransferase
Authors:	Zhong, W, Koay, A, Wong, Y.W, Sahili, A.E, Nah, Q, Kang, C, Poulsen, A, Chionh, Y.K, McBee, M, Matter, A, Hill, J, Lescar, J, Dedon, P.C.
Deposit date:	2018-08-08
Release date:	2019-08-14
Last modified:	2023-11-22
Method:	X-RAY DIFFRACTION (2.75 Å)
Cite:	Targeting the Bacterial Epitranscriptome for Antibiotic Development: Discovery of Novel tRNA-(N1G37) Methyltransferase (TrmD) Inhibitors. Acs Infect Dis., 5, 2019

Crystal structure of SmyD3 in complex with covalent inhibitor 5
Descriptor:	Histone-lysine N-methyltransferase SMYD3, S-ADENOSYLMETHIONINE, ZINC ION, ...
Authors:	Baburajendran, N, Joy, J.
Deposit date:	2018-10-10
Release date:	2019-08-14
Last modified:	2024-03-27
Method:	X-RAY DIFFRACTION (2.351 Å)
Cite:	Discovery of Irreversible Inhibitors Targeting Histone Methyltransferase, SMYD3. Acs Med.Chem.Lett., 10, 2019

Crystal structure of SmyD3 in complex with covalent inhibitor 4
Descriptor:	Histone-lysine N-methyltransferase SMYD3, S-ADENOSYLMETHIONINE, ZINC ION, ...
Authors:	Baburajendran, N, Anna E, J.
Deposit date:	2017-10-11
Release date:	2018-10-17
Last modified:	2019-07-10
Method:	X-RAY DIFFRACTION (2.135 Å)
Cite:	Discovery of Irreversible Inhibitors Targeting Histone Methyltransferase, SMYD3. Acs Med.Chem.Lett., 10, 2019