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4N73
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BU of 4n73 by Molmil
Crystal structure of the ligand binding domain (LBD) of REV-ERB beta bound to Cobalt Protoporphyrin IX
Descriptor: Nuclear receptor subfamily 1 group D member 2, PROTOPORPHYRIN IX CONTAINING CO
Authors:Matta-Camacho, E, Kojetin, D.
Deposit date:2013-10-14
Release date:2014-06-04
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.8662 Å)
Cite:Structure of REV-ERB beta Ligand-binding Domain Bound to a Porphyrin Antagonist.
J.Biol.Chem., 289, 2014
3NY1
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BU of 3ny1 by Molmil
Structure of the ubr-box of the UBR1 ubiquitin ligase
Descriptor: E3 ubiquitin-protein ligase UBR1, ZINC ION
Authors:Matta-Camacho, E, Kozlov, G, Li, F, Gehring, K.
Deposit date:2010-07-14
Release date:2010-08-11
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.085 Å)
Cite:Structural basis of substrate recognition and specificity in the N-end rule pathway.
Nat.Struct.Mol.Biol., 17, 2010
3NY2
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BU of 3ny2 by Molmil
Structure of the ubr-box of UBR2 ubiquitin ligase
Descriptor: E3 ubiquitin-protein ligase UBR2, ZINC ION
Authors:Matta-Camacho, E, Kozlov, G, Li, F, Gehring, K.
Deposit date:2010-07-14
Release date:2010-08-11
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.61 Å)
Cite:Structural basis of substrate recognition and specificity in the N-end rule pathway.
Nat.Struct.Mol.Biol., 17, 2010
3NY3
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BU of 3ny3 by Molmil
Structure of the ubr-box of UBR2 in complex with N-degron
Descriptor: E3 ubiquitin-protein ligase UBR2, N-degron, ZINC ION
Authors:Matta-Camacho, E, Kozlov, G, Li, F, Gehring, K.
Deposit date:2010-07-14
Release date:2010-08-11
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural basis of substrate recognition and specificity in the N-end rule pathway.
Nat.Struct.Mol.Biol., 17, 2010
3PT3
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BU of 3pt3 by Molmil
Crystal structure of the C-terminal lobe of the human UBR5 HECT domain
Descriptor: E3 ubiquitin-protein ligase UBR5
Authors:Matta-Camacho, E, Kozlov, G, Menade, M, Gehring, K.
Deposit date:2010-12-02
Release date:2012-01-25
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Structure of the HECT C-lobe of the UBR5 E3 ubiquitin ligase.
Acta Crystallogr.,Sect.F, 68, 2012
4ZO1
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BU of 4zo1 by Molmil
Crystal Structure of the T3-bound TR-beta Ligand-binding Domain in complex with RXR-alpha
Descriptor: 3,5,3'TRIIODOTHYRONINE, Nuclear receptor coactivator 2, Retinoic acid receptor RXR-alpha, ...
Authors:Bruning, J.B, Kojetin, D.J, Matta-Camacho, E, Hughes, T.S, Srinivasan, S, Nwachukwu, J.C, Cavett, V, Nowak, J, Chalmers, M.J, Marciano, D.P, Kamenecka, T.M, Rance, M, Shulman, A.I, Mangelsdorf, D.J, Griffin, P.R, Nettles, K.W.
Deposit date:2015-05-05
Release date:2015-09-02
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (3.221 Å)
Cite:Structural mechanism for signal transduction in RXR nuclear receptor heterodimers.
Nat Commun, 6, 2015
2KBW
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BU of 2kbw by Molmil
Solution Structure of human Mcl-1 complexed with human Bid_BH3 peptide
Descriptor: BH3-interacting domain death agonist, Induced myeloid leukemia cell differentiation protein Mcl-1
Authors:Liu, Q, Moldoveanu, T, Sprules, T, Matta-Camacho, E, Mansur-Azzam, N, Gehring, K.
Deposit date:2008-12-09
Release date:2009-12-15
Last modified:2022-03-16
Method:SOLUTION NMR
Cite:Apoptotic regulation by MCL-1 through heterodimerization.
J.Biol.Chem., 285, 2010
5TDC
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BU of 5tdc by Molmil
Crystal structure of the human UBR-box domain from UBR1 in complex with monomethylated arginine peptide.
Descriptor: E3 ubiquitin-protein ligase UBR1, NMM-ILE-PHE-SER peptide, SULFATE ION, ...
Authors:Kozlov, G, Munoz-Escobar, J, Matta-Camacho, E, Gehring, K.
Deposit date:2016-09-19
Release date:2017-03-22
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.607 Å)
Cite:Bound Waters Mediate Binding of Diverse Substrates to a Ubiquitin Ligase.
Structure, 25, 2017
3BCY
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BU of 3bcy by Molmil
Crystal structure of YER067W
Descriptor: Protein YER067W
Authors:Kozlov, G, Gehring, K.
Deposit date:2007-11-13
Release date:2008-11-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural and functional study of YER067W, a new protein involved in yeast metabolism control and drug resistance.
Plos One, 5, 2010
5TDA
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BU of 5tda by Molmil
Crystal structure of the UBR-box domain from UBR2 in complex with RLWS N-degron
Descriptor: ARG-LEU-TRP-SER peptide, E3 ubiquitin-protein ligase UBR2, ZINC ION
Authors:Munoz-Escobar, J, Kozlov, G, Gehring, K.
Deposit date:2016-09-19
Release date:2017-03-22
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (0.79 Å)
Cite:Bound Waters Mediate Binding of Diverse Substrates to a Ubiquitin Ligase.
Structure, 25, 2017
5TDD
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BU of 5tdd by Molmil
Human UBR-box from UBR2 in complex with HIFS peptide
Descriptor: 1,2-ETHANEDIOL, E3 ubiquitin-protein ligase UBR2, HIS-ILE-PHE-SER peptide, ...
Authors:Munoz-Escobar, J, Kozlov, G, Gehring, K.
Deposit date:2016-09-19
Release date:2017-03-22
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Bound Waters Mediate Binding of Diverse Substrates to a Ubiquitin Ligase.
Structure, 25, 2017
5UM3
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BU of 5um3 by Molmil
Crystal structure of the V122L mutant of human UBR-box domain from UBR2
Descriptor: E3 ubiquitin-protein ligase UBR2, ZINC ION
Authors:Munoz Escobar, J, Kozlov, G, Gehring, K.
Deposit date:2017-01-26
Release date:2017-03-22
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.198 Å)
Cite:Bound Waters Mediate Binding of Diverse Substrates to a Ubiquitin Ligase.
Structure, 25, 2017
5TDB
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BU of 5tdb by Molmil
Crystal structure of the human UBR-box domain from UBR2 in complex with asymmetrically double methylated arginine peptide
Descriptor: 1,2-ETHANEDIOL, DA2-ILE-PHE-SER peptide, E3 ubiquitin-protein ligase UBR2, ...
Authors:Munoz-Escobar, J, Kozlov, G, Gehring, K.
Deposit date:2016-09-19
Release date:2017-03-22
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.101 Å)
Cite:Bound Waters Mediate Binding of Diverse Substrates to a Ubiquitin Ligase.
Structure, 25, 2017
3NTW
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BU of 3ntw by Molmil
Structure of the MLLE domain of EDD in complex with a PAM2 peptide from Paip1
Descriptor: E3 ubiquitin-protein ligase UBR5, Polyadenylate-binding protein-interacting protein 1
Authors:Kozlov, G, Gehring, K.
Deposit date:2010-07-05
Release date:2011-07-06
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The MLLE domain of the ubiquitin ligase UBR5 binds to its catalytic domain to regulate substrate binding.
J. Biol. Chem., 290, 2015

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