Author results

1A0L
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HUMAN BETA-TRYPTASE: A RING-LIKE TETRAMER WITH ACTIVE SITES FACING A CENTRAL PORE
Descriptor:BETA-TRYPTASE, (2S)-3-(4-carbamimidoylphenyl)-2-hydroxypropanoic acid
Authors:Pereira, P.J.B., Bergner, A., Macedo-Ribeiro, S., Huber, R., Matschiner, G., Fritz, H., Sommerhoff, C.P., Bode, W.
Deposit date:1997-12-03
Release date:1999-03-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Human beta-tryptase is a ring-like tetramer with active sites facing a central pore.
Nature, 392, 1998
1LDT
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COMPLEX OF LEECH-DERIVED TRYPTASE INHIBITOR WITH PORCINE TRYPSIN
Descriptor:TRYPSIN, TRYPTASE INHIBITOR, CALCIUM ION
Authors:Stubbs, M.T.
Deposit date:1997-05-15
Release date:1998-05-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The three-dimensional structure of recombinant leech-derived tryptase inhibitor in complex with trypsin. Implications for the structure of human mast cell tryptase and its inhibition.
J.Biol.Chem., 272, 1997
3BX7
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ENGINEERED HUMAN LIPOCALIN 2 (LCN2) IN COMPLEX WITH THE EXTRACELLULAR DOMAIN OF HUMAN CTLA-4
Descriptor:CYTOTOXIC T-LYMPHOCYTE-ASSOCIATED ANTIGEN 4, ENGINEERED HUMAN LIPOCALIN 2
Authors:Schonfeld, D.L., Chatwell, L., Skerra, A.
Deposit date:2008-01-11
Release date:2009-01-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:High affinity molecular recognition and functional blockade of CTLA-4 by an engineered human lipocalin
To be Published
3BX8
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ENGINEERED HUMAN LIPOCALIN 2 (LCN2), APO-FORM
Descriptor:ENGINEERED HUMAN LIPOCALIN 2, PENTAETHYLENE GLYCOL, 3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL
Authors:Schonfeld, D.L., Chatwell, L., Skerra, A.
Deposit date:2008-01-11
Release date:2009-01-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:High affinity molecular recognition and functional blockade of CTLA-4 by an engineered human lipocalin
To be Published
4GH7
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CRYSTAL STRUCTURE OF ANTICALIN N7A IN COMPLEX WITH ONCOFETAL FIBRONECTIN FRAGMENT FN7B8
Descriptor:Neutrophil gelatinase-associated lipocalin, Fibronectin
Authors:Schiefner, A., Gebauer, M., Skerra, A.
Deposit date:2012-08-07
Release date:2012-12-26
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Combinatorial design of an Anticalin directed against the extra-domain b for the specific targeting of oncofetal fibronectin
J.Mol.Biol., 425, 2013
1TFX
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COMPLEX OF THE SECOND KUNITZ DOMAIN OF TISSUE FACTOR PATHWAY INHIBITOR WITH PORCINE TRYPSIN
Descriptor:TRYPSIN, TISSUE FACTOR PATHWAY INHIBITOR, CALCIUM ION
Authors:Stubbs, M.T., Huber, R.
Deposit date:1997-01-21
Release date:1998-01-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The second Kunitz domain of human tissue factor pathway inhibitor: cloning, structure determination and interaction with factor Xa.
J.Mol.Biol., 269, 1997