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6OKN
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BU of 6okn by Molmil
OX40R (TNFRSF4) bound to Fab 1A7
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Fab 1A7 heavy chain, Fab 1A7 light chain, ...
Authors:Ultsch, M.H, Boenig, G, Harris, S.F.
Deposit date:2019-04-14
Release date:2019-07-10
Last modified:2019-08-14
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:Tetravalent biepitopic targeting enables intrinsic antibody agonism of tumor necrosis factor receptor superfamily members.
Mabs, 11, 2019
7UHC
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BU of 7uhc by Molmil
SARS-CoV-2 spike in complex with AHB2-2GS-SB175
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Multivalent miniprotein inhibitor AHB2-2GS-SB175, ...
Authors:Park, Y.J, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler, D.
Deposit date:2022-03-26
Release date:2022-06-08
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Multivalent designed proteins neutralize SARS-CoV-2 variants of concern and confer protection against infection in mice.
Sci Transl Med, 14, 2022
7UHB
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BU of 7uhb by Molmil
SARS-CoV-2 spike in complex with AHB2-2GS-SB175 (local refinement of the RBD and AHB2)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Multivalent miniprotein inhibitor AHB2-2GS-SB175, Spike glycoprotein
Authors:Park, Y.J, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler, D.
Deposit date:2022-03-26
Release date:2022-06-08
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Multivalent designed proteins neutralize SARS-CoV-2 variants of concern and confer protection against infection in mice.
Sci Transl Med, 14, 2022
6OGX
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BU of 6ogx by Molmil
Ternary complex of OX40R (TNFRSF4) bound to Fab1 and Fab2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab 1 Heavy Chain, Fab1 Light Chain, ...
Authors:Ultsch, M.H, Boenig, G, Harris, S.F.
Deposit date:2019-04-03
Release date:2019-07-10
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.77 Å)
Cite:Tetravalent biepitopic targeting enables intrinsic antibody agonism of tumor necrosis factor receptor superfamily members.
Mabs, 11, 2019
6OKM
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BU of 6okm by Molmil
Human OX40R (TNFRSF4) bound to Fab 3C8
Descriptor: Fab 3C8 Heavy Chain, Fab 3C8 light chain, Tumor necrosis factor receptor superfamily member 4
Authors:Boenig, G, Ultsch, M.H, Harris, S.F.
Deposit date:2019-04-14
Release date:2019-08-28
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Tetravalent biepitopic targeting enables intrinsic antibody agonism of tumor necrosis factor receptor superfamily members.
Mabs, 11, 2019
4CZS
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BU of 4czs by Molmil
Discovery of Glycomimetic Ligands via Genetically-encoded Library of Phage displaying Mannose-peptides
Descriptor: 2-hydroxyethyl alpha-D-mannopyranoside, CALCIUM ION, Concanavalin V, ...
Authors:Ng, S, Lin, E, Tjhung, K.F, Gerlits, O, Sood, A, Kasper, B, Deng, L, Kitov, P.I, Matochko, W.L, Paschal, B.M, Noren, C.J, Klassen, J, Mahal, L.K, Coates, L, Woods, R.J, Derda, R.
Deposit date:2014-04-22
Release date:2015-04-22
Last modified:2022-12-07
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:Genetically-Encoded Fragment-Based Discovery of Glycopeptide Ligands for Carbohydrate-Binding Proteins.
J.Am.Chem.Soc., 137, 2015

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