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1KS9
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BU of 1ks9 by Molmil
Ketopantoate Reductase from Escherichia coli
Descriptor: 2-DEHYDROPANTOATE 2-REDUCTASE
Authors:Matak-Vinkovic, D, Vinkovic, M, Saldanha, S.A, Ashurst, J.A, von Delft, F, Inoue, T, Miguel, R.N, Smith, A.G, Blundell, T.L, Abell, C.
Deposit date:2002-01-11
Release date:2002-01-25
Last modified:2014-11-12
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structure of Escherichia coli ketopantoate reductase at 1.7 A resolution and insight into the enzyme mechanism.
Biochemistry, 40, 2001
3W03
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BU of 3w03 by Molmil
XLF-XRCC4 complex
Descriptor: DNA repair protein XRCC4, Non-homologous end-joining factor 1
Authors:Wu, Q, Ochi, T, Matak-Vinkovic, D, Robinson, C.V, Chirgadze, D.Y, Blundell, T.L.
Deposit date:2012-10-17
Release date:2012-11-07
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (8.492 Å)
Cite:Non-homologous end-joining partners in a helical dance: structural studies of XLF-XRCC4 interactions
Biochem.Soc.Trans., 39, 2011
5MWO
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BU of 5mwo by Molmil
Structure of Mycobacterium Tuberculosis Transcriptional Regulatory Repressor Protein (EthR) in complex with fragment 7E8.
Descriptor: (5-methyl-1-benzothiophen-2-yl)methanol, 1,2-ETHANEDIOL, HTH-type transcriptional regulator EthR
Authors:Mendes, V, Chan, D.S.-H, Thomas, S.E, McConnell, B, Matak-Vinkovic, D, Coyne, A.G, Abell, C, Blundell, T.L.
Deposit date:2017-01-18
Release date:2017-05-31
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.962 Å)
Cite:Fragment Screening against the EthR-DNA Interaction by Native Mass Spectrometry.
Angew. Chem. Int. Ed. Engl., 56, 2017
5MXK
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BU of 5mxk by Molmil
Structure of Mycobacterium Tuberculosis Transcriptional Regulatory Repressor Protein (EthR) in complex with fragment 7G9.
Descriptor: 1,2-ETHANEDIOL, HTH-type transcriptional regulator EthR, ~{N}-(5-oxidanylidene-7,8-dihydro-6~{H}-naphthalen-2-yl)ethanamide
Authors:Mendes, V, Chan, D.S.-H, Thomas, S.E, McConnell, B, Matak-Vinkovic, D, Coyne, A.G, Abell, C, Blundell, T.L.
Deposit date:2017-01-23
Release date:2017-05-31
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.932 Å)
Cite:Fragment Screening against the EthR-DNA Interaction by Native Mass Spectrometry.
Angew. Chem. Int. Ed. Engl., 56, 2017
1PYU
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BU of 1pyu by Molmil
Processed Aspartate Decarboxylase Mutant with Ser25 mutated to Cys
Descriptor: Aspartate 1-decarboxylase alfa chain, Aspartate 1-decarboxylase beta chain, SULFATE ION
Authors:Schmitzberger, F, Kilkenny, M.L, Lobley, C.M.C, Webb, M.E, Vinkovic, M, Matak-Vinkovic, D, Witty, M, Chirgadze, D.Y, Smith, A.G, Abell, C, Blundell, T.L.
Deposit date:2003-07-09
Release date:2003-11-18
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural Constraints on protein self-processing in L-aspartate-alpha-decarboxylase
Embo J., 22, 2003
1PQF
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BU of 1pqf by Molmil
Glycine 24 to Serine mutation of aspartate decarboxylase
Descriptor: Aspartate 1-decarboxylase, SULFATE ION
Authors:Schmitzberger, F, Kilkenny, M.L, Lobley, C.M.C, Webb, M.E, Vinkovic, M, Matak-Vinkovic, D, Witty, M, Chirgadze, D.Y, Smith, A.G, Abell, C, Blundell, T.L.
Deposit date:2003-06-18
Release date:2003-11-18
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural constraints on protein self-processing in L-aspartate-alpha-decarboxylase
Embo J., 22, 2003
1PYQ
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BU of 1pyq by Molmil
Unprocessed Aspartate Decarboxylase Mutant, with Alanine inserted at position 24
Descriptor: Aspartate 1-decarboxylase, SULFATE ION
Authors:Schmitzberger, F, Kilkenny, M.L, Lobley, C.M.C, Webb, M.E, Vinkovic, M, Matak-Vinkovic, D, Witty, M, Chirgadze, D.Y, Smith, A.G, Abell, C, Blundell, T.L.
Deposit date:2003-07-09
Release date:2003-11-18
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural Constraints on protein self-processing in L-aspartate-alpha-decarboxylase
Embo J., 22, 2003
1PPY
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BU of 1ppy by Molmil
Native precursor of pyruvoyl dependent Aspartate decarboxylase
Descriptor: Aspartate 1-decarboxylase precursor, SULFATE ION
Authors:Schmitzberger, F, Kilkenny, M.L, Lobley, C.M.C, Webb, M.E, Vinkovic, M, Matak-Vinkovic, D, Witty, M, Chirgadze, D.Y, Smith, A.G, Abell, C, Blundell, T.L.
Deposit date:2003-06-17
Release date:2003-11-18
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural constraints on protein self-processing in L-aspartate-alpha-decarboxylase
Embo J., 22, 2003
1PQE
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BU of 1pqe by Molmil
S25A mutant of pyruvoyl dependent aspartate decarboxylase
Descriptor: Aspartate 1-decarboxylase
Authors:Schmitzberger, F, Kilkenny, M.L, Lobley, C.M.C, Webb, M.E, Vinkovic, M, Matak-Vinkovic, D, Witty, M, Chirgadze, D.Y, Smith, A.G, Abell, C, Blundell, T.L.
Deposit date:2003-06-18
Release date:2003-11-18
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural constraints on protein self-processing in L-aspartate-alpha-decarboxylase
Embo J., 22, 2003
1PT0
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BU of 1pt0 by Molmil
Unprocessed Pyruvoyl Dependent Aspartate Decarboxylase with an Alanine insertion at position 26
Descriptor: Aspartate 1-decarboxylase, SULFATE ION
Authors:Schmitzberger, F, Kilkenny, M.L, Lobley, C.M.C, Webb, M.E, Vinkovic, M, Matak-Vinkovic, D, Witty, M, Chirgadze, D.Y, Smith, A.G, Abell, C, Blundell, T.L.
Deposit date:2003-06-22
Release date:2003-11-11
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural constraints on protein self-processing in L-aspartate-alpha-decarboxylase
Embo J., 22, 2003
1PT1
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BU of 1pt1 by Molmil
Unprocessed Pyruvoyl Dependent Aspartate Decarboxylase with Histidine 11 Mutated to Alanine
Descriptor: Aspartate 1-decarboxylase, SULFATE ION
Authors:Schmitzberger, F, Kilkenny, M.L, Lobley, C.M.C, Webb, M.E, Vinkovic, M, Matak-Vinkovic, D, Witty, M, Chirgadze, D.Y, Smith, A.G, Abell, C, Blundell, T.L.
Deposit date:2003-06-22
Release date:2003-11-11
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural constraints on protein self-processing in L-aspartate-alpha-decarboxylase
Embo J., 22, 2003
1PQH
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BU of 1pqh by Molmil
Serine 25 to Threonine mutation of aspartate decarboxylase
Descriptor: Aspartate 1-decarboxylase, MALONIC ACID, SODIUM ION
Authors:Schmitzberger, F, Kilkenny, M.L, Lobley, C.M.C, Webb, M.E, Vinkovic, M, Matak-Vinkovic, D, Witty, M, Chirgadze, D.Y, Smith, A.G, Abell, C, Blundell, T.L.
Deposit date:2003-06-18
Release date:2003-11-18
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.29 Å)
Cite:Structural constraints on protein self-processing in L-aspartate-alpha-decarboxylase
Embo J., 22, 2003
5HOI
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BU of 5hoi by Molmil
Crystal structure of the carboxy-terminal domain of yeast Ctf4 bound to Tof2.
Descriptor: DNA polymerase alpha-binding protein, Topoisomerase 1-associated factor 2
Authors:Simon, A.C, Pellegrini, L.
Deposit date:2016-01-19
Release date:2016-06-22
Last modified:2016-08-17
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Ctf4 Is a Hub in the Eukaryotic Replisome that Links Multiple CIP-Box Proteins to the CMG Helicase.
Mol.Cell, 63, 2016
5HOG
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BU of 5hog by Molmil
Crystal structure of the carboxy-terminal domain of yeast Ctf4 bound to Dna2.
Descriptor: DNA polymerase alpha-binding protein, Dna2p
Authors:Simon, A.C, Pellegrini, L.
Deposit date:2016-01-19
Release date:2016-06-22
Last modified:2016-08-17
Method:X-RAY DIFFRACTION (3.092 Å)
Cite:Ctf4 Is a Hub in the Eukaryotic Replisome that Links Multiple CIP-Box Proteins to the CMG Helicase.
Mol.Cell, 63, 2016
5HDI
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BU of 5hdi by Molmil
Structural characterization of CYP144A1, a Mycobacterium tuberculosis cytochrome P450
Descriptor: Cytochrome P450 144, PROTOPORPHYRIN IX CONTAINING FE
Authors:Chenge, J, Driscoll, M.D, McLean, K.J, Munro, A.W, Leys, D.
Deposit date:2016-01-05
Release date:2016-05-04
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.54 Å)
Cite:Structural characterization of CYP144A1 - a cytochrome P450 enzyme expressed from alternative transcripts in Mycobacterium tuberculosis.
Sci Rep, 6, 2016
3ESL
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BU of 3esl by Molmil
Crystal structure of the conserved N-terminal domain of the mitotic checkpoint component BUB1
Descriptor: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Checkpoint serine/threonine-protein kinase BUB1
Authors:Bolanos-Garcia, V.M, Chirgadze, D.Y, Blundell, T.L.
Deposit date:2008-10-06
Release date:2009-02-17
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:The Crystal Structure of the N-Terminal Region of BUB1 Provides Insight into the Mechanism of BUB1 Recruitment to Kinetochores.
Structure, 17, 2009
4RAV
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BU of 4rav by Molmil
Crystal structure of scFvC4 in complex with the first 17 AA of huntingtin
Descriptor: Huntingtin, SULFATE ION, Single-chain Fv, ...
Authors:De Genst, E, Chirgadze, D.Y, Dobson, C.M.
Deposit date:2014-09-11
Release date:2015-07-29
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of a single-chain fv bound to the 17 N-terminal residues of huntingtin provides insights into pathogenic amyloid formation and suppression.
J.Mol.Biol., 427, 2015
5OHG
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BU of 5ohg by Molmil
enolase in complex with RNase E
Descriptor: Enolase, MAGNESIUM ION, PHOSPHATE ION, ...
Authors:Du, D, Luisi, B.F.
Deposit date:2017-07-16
Release date:2017-07-26
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.997 Å)
Cite:Analysis of the natively unstructured RNA/protein-recognition core in the Escherichia coli RNA degradosome and its interactions with regulatory RNA/Hfq complexes.
Nucleic Acids Res., 46, 2018
3SI5
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BU of 3si5 by Molmil
Kinetochore-BUBR1 kinase complex
Descriptor: Mitotic checkpoint serine/threonine-protein kinase BUB1 beta, Protein CASC5
Authors:Blundell, T.L, Chirgadze, D.Y, Bolanos-Garcia, V.M.
Deposit date:2011-06-17
Release date:2011-10-26
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of a Blinkin-BUBR1 Complex Reveals an Interaction Crucial for Kinetochore-Mitotic Checkpoint Regulation via an Unanticipated Binding Site.
Structure, 19, 2011
3ZNG
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BU of 3zng by Molmil
Ankyrin repeat and SOCS-box protein 9 (ASB9) in complex with ElonginB and ElonginC
Descriptor: 1,2-ETHANEDIOL, ANKYRIN REPEAT AND SOCS BOX PROTEIN 9, TRANSCRIPTION ELONGATION FACTOR B POLYPEPTIDE 1, ...
Authors:Thomas, J, Van Molle, I, Ciulli, A.
Deposit date:2013-02-14
Release date:2013-12-04
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Multimeric Complexes Among Ankyrin-Repeat and Socs-Box Protein 9 (Asb9), Elonginbc, and Cullin 5: Insights Into the Structure and Assembly of Ecs-Type Cullin-Ring E3 Ubiquitin Ligases.
Biochemistry, 52, 2013
4C8H
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BU of 4c8h by Molmil
Crystal structure of the C-terminal region of yeast Ctf4, selenomethionine protein.
Descriptor: CTF4
Authors:Simon, A.C, Pellegrini, L.
Deposit date:2013-10-01
Release date:2014-04-30
Last modified:2014-06-18
Method:X-RAY DIFFRACTION (2.691 Å)
Cite:A Ctf4 Trimer Couples the Cmg Helicase to DNA Polymerase Alpha in the Eukaryotic Replisome
Nature, 510, 2014
4C95
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BU of 4c95 by Molmil
Crystal structure of the carboxy-terminal domain of yeast Ctf4 bound to Sld5
Descriptor: DNA POLYMERASE ALPHA-BINDING PROTEIN, DNA REPLICATION COMPLEX GINS PROTEIN SLD5
Authors:Simon, A.C, Pellegrini, L.
Deposit date:2013-10-02
Release date:2014-04-30
Last modified:2014-06-18
Method:X-RAY DIFFRACTION (2.694 Å)
Cite:A Ctf4 Trimer Couples the Cmg Helicase to DNA Polymerase a in the Eukaryotic Replisome
Nature, 510, 2014
4C93
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BU of 4c93 by Molmil
Crystal structure of the carboxy-terminal domain of yeast Ctf4 bound to Pol alpha.
Descriptor: DNA POLYMERASE ALPHA CATALYTIC SUBUNIT A, DNA POLYMERASE ALPHA-BINDING PROTEIN
Authors:Simon, A.C, Pellegrini, L.
Deposit date:2013-10-02
Release date:2014-04-30
Last modified:2014-06-18
Method:X-RAY DIFFRACTION (2.694 Å)
Cite:A Ctf4 Trimer Couples the Cmg Helicase to DNA Polymerase a in the Eukaryotic Replisome
Nature, 510, 2014
4C8S
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BU of 4c8s by Molmil
Crystal structure of the C-terminal region of yeast Ctf4
Descriptor: DNA POLYMERASE ALPHA-BINDING PROTEIN
Authors:Simon, A.C, Pellegrini, L.
Deposit date:2013-10-01
Release date:2014-04-30
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3 Å)
Cite:A Ctf4 Trimer Couples the Cmg Helicase to DNA Polymerase a in the Eukaryotic Replisome
Nature, 510, 2014
5MQI
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BU of 5mqi by Molmil
Crystal structure of the N-terminal domain of human Timeless
Descriptor: Protein timeless homolog,Protein timeless homolog, SULFATE ION
Authors:Holzer, S, Kilkenny, M.L, Pellegrini, L.
Deposit date:2016-12-20
Release date:2017-03-08
Last modified:2017-05-31
Method:X-RAY DIFFRACTION (1.847 Å)
Cite:Crystal structure of the N-terminal domain of human Timeless and its interaction with Tipin.
Nucleic Acids Res., 45, 2017

 

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