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1XLU
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X-RAY STRUCTURE OF DI-ISOPROPYL-PHOSPHORO-FLUORIDATE (DFP) INHIBITED BUTYRYLCHOLINESTERASE AFTER AGING
Descriptor:BUTYRYLCHOLINESTERASE, N-ACETYL-D-GLUCOSAMINE, BETA-L-FUCOSE, ...
Authors:Nachon, F., Asojo, O.A., Borgstahl, G.E.O., Masson, P., Lockridge, O.
Deposit date:2004-09-30
Release date:2005-02-01
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.198 Å)
Cite:Role of Water in Aging of Human Butyrylcholinesterase Inhibited by Echothiophate: The Crystal Structure Suggests Two Alternative Mechanisms of Aging
Biochemistry, 44, 2005
1XLV
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ETHYLPHOSPHORYLATED BUTYRYLCHOLINESTERASE (AGED) OBTAINED BY REACTION WITH ECHOTHIOPHATE
Descriptor:BUTYRYLCHOLINESTERASE, N-ACETYL-D-GLUCOSAMINE, BETA-L-FUCOSE, ...
Authors:Nachon, F., Asojo, O.A., Borgstahl, G.E.O., Masson, P., Lockridge, O.
Deposit date:2004-09-30
Release date:2005-02-01
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.247 Å)
Cite:Role of Water in Aging of Human Butyrylcholinesterase Inhibited by Echothiophate: The Crystal Structure Suggests Two Alternative Mechanisms of Aging
Biochemistry, 44, 2005
1XLW
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DIETHYLPHOSPHORYLATED BUTYRYLCHOLINESTERASE (NONAGED) OBTAINED BY REACTION WITH ECHOTHIOPHATE
Descriptor:BUTYRYLCHOLINESTERASE, N-ACETYL-D-GLUCOSAMINE, BETA-L-FUCOSE, ...
Authors:Nachon, F., Asojo, O.A., Borgstahl, G.E.O., Masson, P., Lockridge, O.
Deposit date:2004-09-30
Release date:2005-02-01
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Role of Water in Aging of Human Butyrylcholinesterase Inhibited by Echothiophate: The Crystal Structure Suggests Two Alternative Mechanisms of Aging
Biochemistry, 44, 2005
1P0I
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CRYSTAL STRUCTURE OF HUMAN BUTYRYL CHOLINESTERASE
Descriptor:Cholinesterase, N-ACETYL-D-GLUCOSAMINE, ALPHA-L-FUCOSE, ...
Authors:Nicolet, Y., Lockridge, O., Masson, P., Fontecilla-Camps, J.C., Nachon, F.
Deposit date:2003-04-10
Release date:2003-08-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of human butyrylcholinesterase and of its complexes with substrate and products.
J.Biol.Chem., 278, 2003
1P0M
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CRYSTAL STRUCTURE OF HUMAN BUTYRYL CHOLINESTERASE IN COMPLEX WITH A CHOLINE MOLECULE
Descriptor:Cholinesterase, N-ACETYL-D-GLUCOSAMINE, ALPHA-L-FUCOSE, ...
Authors:Nicolet, Y., Lockridge, O., Masson, P., Fontecilla-Camps, J.C., Nachon, F.
Deposit date:2003-04-10
Release date:2003-08-05
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.38 Å)
Cite:Crystal structure of human butyrylcholinesterase and of its complexes with substrate and products.
J.Biol.Chem., 278, 2003
1P0P
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CRYSTAL STRUCTURE OF SOMAN-AGED HUMAN BUTYRYL CHOLINESTERASE IN COMPLEX WITH THE SUBSTRATE ANALOG BUTYRYLTHIOCHOLINE
Descriptor:Cholinesterase, N-ACETYL-D-GLUCOSAMINE, ALPHA-L-FUCOSE, ...
Authors:Nicolet, Y., Lockridge, O., Masson, P., Fontecilla-Camps, J.C., Nachon, F.
Deposit date:2003-04-10
Release date:2003-08-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of human butyrylcholinesterase and of its complexes with substrate and products.
J.Biol.Chem., 278, 2003
1P0Q
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CRYSTAL STRUCTURE OF SOMAN-AGED HUMAN BUTYRYL CHOLINESTERASE
Descriptor:Cholinesterase, N-ACETYL-D-GLUCOSAMINE, ALPHA-L-FUCOSE, ...
Authors:Nicolet, Y., Lockridge, O., Masson, P., Fontecilla-Camps, J.C., Nachon, F.
Deposit date:2003-04-10
Release date:2003-08-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.43 Å)
Cite:Crystal structure of human butyrylcholinesterase and of its complexes with substrate and products.
J.Biol.Chem., 278, 2003
2VC5
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STRUCTURAL BASIS FOR NATURAL LACTONASE AND PROMISCUOUS PHOSPHOTRIESTERASE ACTIVITIES
Descriptor:ARYLDIALKYLPHOSPHATASE, FE (III) ION, COBALT (II) ION, ...
Authors:Elias, M., Dupuy, J., Merone, L., Mandrich, L., Moniot, S., Lecomte, C., Rossi, M., Masson, P., Manco, G., Chabriere, E.
Deposit date:2007-09-18
Release date:2008-04-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural Basis for Natural Lactonase and Promiscuous Phosphotriesterase Activities.
J.Mol.Biol., 379, 2008
2V96
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STRUCTURE OF THE UNPHOTOLYSED COMPLEX OF TCACHE WITH 1-(2- NITROPHENYL)-2,2,2-TRIFLUOROETHYL-ARSENOCHOLINE AT 100K
Descriptor:ACETYLCHOLINESTERASE, 1-(2-nitrophenyl)-2,2,2-trifluoroethyl]-arsenocholine, N-ACETYL-D-GLUCOSAMINE
Authors:Colletier, J.-P., Sanson, B., Royant, A., Specht, A., Nachon, F., Masson, P., Zaccai, G., Sussman, J.L., Goeldner, M., Silman, I., Bourgeois, D., Weik, M.
Deposit date:2007-08-22
Release date:2007-11-20
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Use of a 'Caged' Analog to Study Traffic of Choline within Acetylcholinesterase by Kinetic Crystallography
Acta Crystallogr.,Sect.D, 63, 2007
2V97
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STRUCTURE OF THE UNPHOTOLYSED COMPLEX OF TCACHE WITH 1-(2- NITROPHENYL)-2,2,2-TRIFLUOROETHYL-ARSENOCHOLINE AFTER A 9 SECONDS ANNEALING TO ROOM TEMPERATURE
Descriptor:ACETYLCHOLINESTERASE, CHLORIDE ION, 1-(2-nitrophenyl)-2,2,2-trifluoroethyl]-arsenocholine, ...
Authors:Colletier, J.-P., Sanson, B., Royant, A., Specht, A., Nachon, F., Masson, P., Zaccai, G., Sussman, J.L., Goeldner, M., Silman, I., Bourgeois, D., Weik, M.
Deposit date:2007-08-22
Release date:2007-11-20
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Use of a 'Caged' Analog to Study Traffic of Choline within Acetylcholinesterase by Kinetic Crystallography
Acta Crystallogr.,Sect.D, 63, 2007
2V98
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STRUCTURE OF THE COMPLEX OF TCACHE WITH 1-(2-NITROPHENYL)-2,2,2- TRIFLUOROETHYL-ARSENOCHOLINE AFTER A 9 SECONDS ANNEALING TO ROOM TEMPERATURE, DURING THE FIRST 5 SECONDS OF WHICH LASER IRRADIATION AT 266NM TOOK PLACE
Descriptor:ACETYLCHOLINESTERASE, CHLORIDE ION, 1-(2-nitrophenyl)-2,2,2-trifluoroethyl]-arsenocholine, ...
Authors:Colletier, J.-P., Sanson, B., Royant, A., Specht, A., Nachon, F., Masson, P., Zaccai, G., Sussman, J.L., Goeldner, M., Silman, I., Bourgeois, D., Weik, M.
Deposit date:2007-08-22
Release date:2007-11-20
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (3 Å)
Cite:Use of a 'Caged' Analog to Study Traffic of Choline within Acetylcholinesterase by Kinetic Crystallography
Acta Crystallogr.,Sect.D, 63, 2007
2VA9
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STRUCTURE OF NATIVE TCACHE AFTER A 9 SECONDS ANNEALING TO ROOM TEMPERATURE DURING THE FIRST 5 SECONDS OF WHICH LASER IRRADIATION AT 266NM TOOK PLACE
Descriptor:ACETYLCHOLINESTERASE, N-ACETYL-D-GLUCOSAMINE
Authors:Colletier, J.-P., Sanson, B., Royant, A., Specht, A., Nachon, F., Masson, P., Zaccai, G., Sussman, J.L., Goeldner, M., Silman, I., Bourgeois, D., Weik, M.
Deposit date:2007-08-30
Release date:2007-11-20
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Use of a 'Caged' Analog to Study Traffic of Choline within Acetylcholinesterase by Kinetic Crystallography
Acta Crystallogr.,Sect.D, 63, 2007
2VC7
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STRUCTURAL BASIS FOR NATURAL LACTONASE AND PROMISCUOUS PHOSPHOTRIESTERASE ACTIVITIES
Descriptor:ARYLDIALKYLPHOSPHATASE, FE (III) ION, COBALT (II) ION, ...
Authors:Elias, M., Dupuy, J., Merone, L., Mandrich, L., Moniot, S., Rochu, D., Lecomte, C., Rossi, M., Masson, P., Manco, G., Chabriere, E.
Deposit date:2007-09-19
Release date:2008-04-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structural Basis for Natural Lactonase and Promiscuous Phosphotriesterase Activities.
J.Mol.Biol., 379, 2008
2WFZ
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NON-AGED CONJUGATE OF TORPEDO CALIFORNICA ACETYLCHOLINESTERASE WITH SOMAN
Descriptor:ACETYLCHOLINESTERASE, N-ACETYL-D-GLUCOSAMINE, ALPHA-L-FUCOSE, ...
Authors:Sanson, B., Nachon, F., Colletier, J.P., Froment, M.T., Toker, L., Greenblatt, H.M., Sussman, J.L., Ashani, Y., Masson, P., Silman, I., Weik, M.
Deposit date:2009-04-15
Release date:2009-08-11
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Crystallographic Snapshots of Nonaged and Aged Conjugates of Soman with Acetylcholinesterase, and of a Ternary Complex of the Aged Conjugate with Pralidoxime.
J.Med.Chem., 52, 2009
2WG0
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AGED CONJUGATE OF TORPEDO CALIFORNICA ACETYLCHOLINESTERASE WITH SOMAN (OBTAINED BY IN CRYSTALLO AGING)
Descriptor:ACETYLCHOLINESTERASE, N-ACETYL-D-GLUCOSAMINE, CHLORIDE ION, ...
Authors:Sanson, B., Nachon, F., Colletier, J.P., Froment, M.T., Toker, L., Greenblatt, H.M., Sussman, J.L., Ashani, Y., Masson, P., Silman, I., Weik, M.
Deposit date:2009-04-15
Release date:2009-08-11
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystallographic Snapshots of Nonaged and Aged Conjugates of Soman with Acetylcholinesterase, and of a Ternary Complex of the Aged Conjugate with Pralidoxime.
J.Med.Chem., 52, 2009
2WG1
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TERNARY COMPLEX OF THE AGED CONJUGATE OF TORPEDO CALIFORNICA ACEYLCHOLINESTERASE WITH SOMAN AND 2-PAM
Descriptor:ACETYLCHOLINESTERASE, N-ACETYL-D-GLUCOSAMINE, ALPHA-L-FUCOSE, ...
Authors:Sanson, B., Nachon, F., Colletier, J.P., Froment, M.T., Toker, L., Greenblatt, H.M., Sussman, J.L., Ashani, Y., Masson, P., Silman, I., Weik, M.
Deposit date:2009-04-15
Release date:2009-08-11
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystallographic Snapshots of Nonaged and Aged Conjugates of Soman with Acetylcholinesterase, and of a Ternary Complex of the Aged Conjugate with Pralidoxime.
J.Med.Chem., 52, 2009
2WG2
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NON-AGED CONJUGATE OF TORPEDO CALIFORNICA ACETYLCHOLINESTERASE WITH SOMAN (ALTERNATIVE REFINEMENT)
Descriptor:ACETYLCHOLINESTERASE, N-ACETYL-D-GLUCOSAMINE, ALPHA-L-FUCOSE, ...
Authors:Sanson, B., Nachon, F., Colletier, J.P., Froment, M.T., Toker, L., Greenblatt, H.M., Sussman, J.L., Ashani, Y., Masson, P., Silman, I., Weik, M.
Deposit date:2009-04-15
Release date:2010-04-21
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Crystallographic Snapshots of Nonaged and Aged Conjugates of Soman with Acetylcholinesterase, and of a Ternary Complex of the Aged Conjugate with Pralidoxime.
J.Med.Chem., 52, 2009
2WID
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NONAGED FORM OF HUMAN BUTYRYLCHOLINESTERASE INHIBITED BY TABUN ANALOGUE TA1
Descriptor:CHOLINESTERASE, ETHYL HYDROGEN DIETHYLAMIDOPHOSPHATE, SODIUM ION, ...
Authors:Carletti, E., Aurbek, N., Gillon, E., Loiodice, M., Nicolet, Y., Fontecilla, J., Masson, P., Thiermann, H., Nachon, F., Worek, F.
Deposit date:2009-05-11
Release date:2009-05-19
Last modified:2019-02-06
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure-activity analysis of aging and reactivation of human butyrylcholinesterase inhibited by analogues of tabun.
Biochem. J., 421, 2009
2WIF
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AGED FORM OF HUMAN BUTYRYLCHOLINESTERASE INHIBITED BY TABUN ANALOGUE TA1
Descriptor:CHOLINESTERASE, SODIUM ION, CHLORIDE ION, ...
Authors:Carletti, E., Aurbek, N., Gillon, E., Loiodice, M., Nicolet, Y., Fontecilla, J., Masson, P., Thiermann, H., Nachon, F., Worek, F.
Deposit date:2009-05-11
Release date:2009-05-19
Last modified:2019-02-06
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structure-activity analysis of aging and reactivation of human butyrylcholinesterase inhibited by analogues of tabun.
Biochem. J., 421, 2009
2WIG
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NONAGED FORM OF HUMAN BUTYRYLCHOLINESTERASE INHIBITED BY TABUN ANALOGUE TA4
Descriptor:CHOLINESTERASE, ETHYL HYDROGEN METHYLAMIDOPHOSPHATE, SODIUM ION, ...
Authors:Carletti, E., Aurbek, N., Gillon, E., Loiodice, M., Nicolet, Y., Fontecilla, J., Masson, P., Thiermann, H., Nachon, F., Worek, F.
Deposit date:2009-05-11
Release date:2009-05-19
Last modified:2019-02-06
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structure-activity analysis of aging and reactivation of human butyrylcholinesterase inhibited by analogues of tabun.
Biochem. J., 421, 2009
2WIJ
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NONAGED FORM OF HUMAN BUTYRYLCHOLINESTERASE INHIBITED BY TABUN ANALOGUE TA5
Descriptor:CHOLINESTERASE, ethyl hydrogen ethylamidophosphate, SODIUM ION, ...
Authors:Carletti, E., Aurbek, N., Gillon, E., Loiodice, M., Nicolet, Y., Fontecilla, J., Masson, P., Thiermann, H., Nachon, F., Worek, F.
Deposit date:2009-05-12
Release date:2009-05-19
Last modified:2019-02-06
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure-activity analysis of aging and reactivation of human butyrylcholinesterase inhibited by analogues of tabun.
Biochem. J., 421, 2009
2WIK
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NONAGED FORM OF HUMAN BUTYRYLCHOLINESTERASE INHIBITED BY TABUN ANALOGUE TA6
Descriptor:CHOLINESTERASE, ETHYL HYDROGEN PROPYLAMIDOPHOSPHATE, CHLORIDE ION, ...
Authors:Carletti, E., Aurbek, N., Gillon, E., Loiodice, M., Nicolet, Y., Fontecilla, J., Masson, P., Thiermann, H., Nachon, F., Worek, F.
Deposit date:2009-05-12
Release date:2009-05-19
Last modified:2019-02-06
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure-activity analysis of aging and reactivation of human butyrylcholinesterase inhibited by analogues of tabun.
Biochem. J., 421, 2009
2WIL
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AGED FORM OF HUMAN BUTYRYLCHOLINESTERASE INHIBITED BY TABUN ANALOGUE TA5
Descriptor:CHOLINESTERASE, ethylphosphoramidic acid, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Carletti, E., Aurbek, N., Gillon, E., Loiodice, M., Nicolet, Y., Fontecilla, J., Masson, P., Thiermann, H., Nachon, F., Worek, F.
Deposit date:2009-05-12
Release date:2009-05-26
Last modified:2019-02-06
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structure-Activity Analysis of Aging and Reactivation of Human Butyrylcholinesterase Inhibited by Analogues of Tabun
Biochem.J., 421, 2009
2WSL
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AGED FORM OF HUMAN BUTYRYLCHOLINESTERASE INHIBITED BY TABUN ANALOGUE TA4
Descriptor:CHOLINESTERASE, N-ACETYL-D-GLUCOSAMINE, BETA-L-FUCOSE, ...
Authors:Carletti, E., Aurbek, N., Gillon, E., Loiodice, M., Nicolet, Y., Fontecilla, J., Masson, P., Thiermann, H., Nachon, F., Worek, F.
Deposit date:2009-09-08
Release date:2009-09-15
Last modified:2018-02-28
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure-activity analysis of aging and reactivation of human butyrylcholinesterase inhibited by analogues of tabun.
Biochem. J., 421, 2009
2XMB
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G117H MUTANT OF HUMAN BUTYRYLCHOLINESTERASE IN COMPLEX WITH SULFATE
Descriptor:CHOLINESTERASE, UNKNOWN ATOM OR ION, CHLORIDE ION, ...
Authors:Nachon, F., Carletti, E., Wandhammer, M., Nicolet, Y., Schopfer, L.M., Masson, P., Lockridge, O.
Deposit date:2010-07-27
Release date:2010-12-01
Last modified:2019-02-06
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:X-Ray Crystallographic Snapshots of Reaction Intermediates in the G117H Mutant of Human Butyrylcholinesterase, a Nerve Agent Target Engineered Into a Catalytic Bioscavenge
Biochem.J., 434, 2011
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