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4QVB
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MYCOBACTERIUM TUBERCULOSIS PROTEIN RV1155 IN COMPLEX WITH CO-ENZYME F420
Descriptor:Rv1155 protein, FORMIC ACID, 1,3-PROPANDIOL, ...
Authors:Mashalidis, E.H., Gittis, A.G., Tomczak, A., Abell, C., Barry III, C.E., Garboczi, D.N.
Deposit date:2014-07-14
Release date:2015-02-25
Last modified:2015-05-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Molecular insights into the binding of coenzyme F420 to the conserved protein Rv1155 from Mycobacterium tuberculosis.
Protein Sci., 24, 2015
5CKR
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CRYSTAL STRUCTURE OF MRAY IN COMPLEX WITH MURAYMYCIN D2
Descriptor:Phospho-N-acetylmuramoyl-pentapeptide-transferase, Muraymycin D2
Authors:Lee, S.Y., Chung, B.C., Mashalidis, E.H., Tanino, T., Kim, M., Hong, J., Ichikawa, S.
Deposit date:2015-07-15
Release date:2016-03-02
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Structural insights into inhibition of lipid I production in bacterial cell wall synthesis.
Nature, 533, 2016
6BW5
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HUMAN GPT (DPAGT1) IN COMPLEX WITH TUNICAMYCIN
Descriptor:UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase, Tunicamycin, (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate
Authors:Yoo, J., Kuk, A.C.Y., Mashalidis, E.H., Lee, S.-Y.
Deposit date:2017-12-14
Release date:2018-02-21
Last modified:2018-03-21
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:GlcNAc-1-P-transferase-tunicamycin complex structure reveals basis for inhibition of N-glycosylation.
Nat. Struct. Mol. Biol., 25, 2018
6BW6
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HUMAN GPT (DPAGT1) H129 VARIANT IN COMPLEX WITH TUNICAMYCIN
Descriptor:UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase, Tunicamycin, (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate
Authors:Yoo, J., Kuk, A.C.Y., Mashalidis, E.H., Lee, S.-Y.
Deposit date:2017-12-14
Release date:2018-02-21
Last modified:2018-03-21
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:GlcNAc-1-P-transferase-tunicamycin complex structure reveals basis for inhibition of N-glycosylation.
Nat. Struct. Mol. Biol., 25, 2018
5T77
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CRYSTAL STRUCTURE OF THE MOP FLIPPASE MURJ
Descriptor:Putative lipid II flippase MurJ, CHLORIDE ION, ZINC ION, ...
Authors:Kuk, A.C.Y., Lee, S.-Y.
Deposit date:2016-09-02
Release date:2016-12-28
Last modified:2017-02-15
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of the MOP flippase MurJ in an inward-facing conformation.
Nat. Struct. Mol. Biol., 24, 2017