2MTG
 
 | | Solution structure of the RRM1 of human LARP6 | | Descriptor: | La-related protein 6 | | Authors: | Martino, L, Atkinson, A.R, Kelly, G, Conte, M.R. | | Deposit date: | 2014-08-18 | | Release date: | 2014-12-24 | | Last modified: | 2015-01-28 | | Method: | SOLUTION NMR | | Cite: | Synergic interplay of the La motif, RRM1 and the interdomain linker of LARP6 in the recognition of collagen mRNA expands the RNA binding repertoire of the La module.
Nucleic Acids Res., 43, 2015
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2MTF
 | | Solution structure of the La motif of human LARP6 | | Descriptor: | La-related protein 6 | | Authors: | Martino, L, Salisbury, N.JH, Atkinson, A.R, Kelly, G, Conte, M.R. | | Deposit date: | 2014-08-18 | | Release date: | 2014-12-24 | | Last modified: | 2023-06-14 | | Method: | SOLUTION NMR | | Cite: | Synergic interplay of the La motif, RRM1 and the interdomain linker of LARP6 in the recognition of collagen mRNA expands the RNA binding repertoire of the La module.
Nucleic Acids Res., 43, 2015
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2JT7
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2KFW
 | | Solution structure of full-length SlyD from E.coli | | Descriptor: | FKBP-type peptidyl-prolyl cis-trans isomerase slyD | | Authors: | Martino, L, He, Y, Hands-Taylor, K.L, Valentine, E.R, Kelly, G, Giancola, C, Conte, M.R. | | Deposit date: | 2009-02-28 | | Release date: | 2009-09-15 | | Last modified: | 2020-02-26 | | Method: | SOLUTION NMR | | Cite: | The interaction of the Escherichia coli protein SlyD with nickel ions illuminates the mechanism of regulation of its peptidyl-prolyl isomerase activity.
Febs J., 276, 2009
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2IDN
 | | NMR structure of a new modified Thrombin Binding Aptamer containing a 5'-5' inversion of polarity site | | Descriptor: | 3'-D(P*GP*G*T)-5'-5'-D(P*TP*GP*GP*TP*GP*TP*GP*GP*TP*TP*GP*G)-3' | | Authors: | Randazzo, A, Martino, L, Virno, A, Mayol, L, Giancola, C. | | Deposit date: | 2006-09-15 | | Release date: | 2007-01-09 | | Last modified: | 2022-03-09 | | Method: | SOLUTION NMR | | Cite: | A new modified thrombin binding aptamer containing a 5'-5' inversion of polarity site.
Nucleic Acids Res., 34, 2006
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6GZY
 | | HOIP-fragment5 complex | | Descriptor: | 1,2-ETHANEDIOL, E3 ubiquitin-protein ligase RNF31, SODIUM ION, ... | | Authors: | Johansson, H, Tsai, Y.C.I, Fantom, K, Chung, C.W, Martino, L, House, D, Rittinger, K. | | Deposit date: | 2018-07-05 | | Release date: | 2019-01-30 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | Fragment-Based Covalent Ligand Screening Enables Rapid Discovery of Inhibitors for the RBR E3 Ubiquitin Ligase HOIP.
J. Am. Chem. Soc., 141, 2019
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6I9B
 | | NMR structure of the La module from human LARP4A | | Descriptor: | La-related protein 4 | | Authors: | Conte, M.R, Martino, L, Atkinson, R.A, Kelly, G, Cruz-Gallardo, I, De Tito, S, Trotta, R. | | Deposit date: | 2018-11-22 | | Release date: | 2019-03-13 | | Last modified: | 2023-06-14 | | Method: | SOLUTION NMR | | Cite: | LARP4A recognizes polyA RNA via a novel binding mechanism mediated by disordered regions and involving the PAM2w motif, revealing interplay between PABP, LARP4A and mRNA.
Nucleic Acids Res., 47, 2019
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5UDH
 | | HHARI/ARIH1-UBCH7~Ubiquitin | | Descriptor: | E3 ubiquitin-protein ligase ARIH1, Ubiquitin C variant, Ubiquitin-conjugating enzyme E2 L3, ... | | Authors: | Miller, D.J, Schulman, B.A. | | Deposit date: | 2016-12-27 | | Release date: | 2017-06-14 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (3.24 Å) | | Cite: | Structural Studies of HHARI/UbcH7Ub Reveal Unique E2Ub Conformational Restriction by RBR RING1.
Structure, 25, 2017
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3PKN
 | | Crystal structure of MLLE domain of poly(A) binding protein in complex with PAM2 motif of La-related protein 4 (LARP4) | | Descriptor: | IODIDE ION, La-related protein 4, Polyadenylate-binding protein 1, ... | | Authors: | Xie, J, Kozlov, G, Gehring, K. | | Deposit date: | 2010-11-11 | | Release date: | 2011-01-12 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | La-Related Protein 4 Binds Poly(A), Interacts with the Poly(A)-Binding Protein MLLE Domain via a Variant PAM2w Motif, and Can Promote mRNA Stability.
Mol.Cell.Biol., 31, 2011
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6EYR
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6EYT
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4LOO
 | | Structural basis of autoactivation of p38 alpha induced by TAB1 (Monoclinic crystal form) | | Descriptor: | 4-(4-FLUOROPHENYL)-1-(4-PIPERIDINYL)-5-(2-AMINO-4-PYRIMIDINYL)-IMIDAZOLE, Mitogen-activated protein kinase 14, TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 | | Authors: | Chaikuad, A, DeNicola, G.F, Krojer, T, Allerston, C.K, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Marber, M.S, Knapp, S, Structural Genomics Consortium (SGC) | | Deposit date: | 2013-07-13 | | Release date: | 2013-08-21 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Mechanism and consequence of the autoactivation of p38 alpha mitogen-activated protein kinase promoted by TAB1.
Nat.Struct.Mol.Biol., 20, 2013
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4LOQ
 | | Structural basis of autoactivation of p38 alpha induced by TAB1 (Tetragonal crystal form with bound sulphate) | | Descriptor: | 1,2-ETHANEDIOL, 4-(4-FLUOROPHENYL)-1-(4-PIPERIDINYL)-5-(2-AMINO-4-PYRIMIDINYL)-IMIDAZOLE, Mitogen-activated protein kinase 14, ... | | Authors: | Chaikuad, A, DeNicola, G.F, Yue, W.W, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Marber, M.S, Knapp, S, Structural Genomics Consortium (SGC) | | Deposit date: | 2013-07-13 | | Release date: | 2013-08-21 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.319 Å) | | Cite: | Mechanism and consequence of the autoactivation of p38 alpha mitogen-activated protein kinase promoted by TAB1.
Nat.Struct.Mol.Biol., 20, 2013
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4LOP
 | | Structural basis of autoactivation of p38 alpha induced by TAB1 (Tetragonal crystal form) | | Descriptor: | 1,2-ETHANEDIOL, 4-(4-FLUOROPHENYL)-1-(4-PIPERIDINYL)-5-(2-AMINO-4-PYRIMIDINYL)-IMIDAZOLE, L(+)-TARTARIC ACID, ... | | Authors: | Chaikuad, A, DeNicola, G.F, Krojer, T, Allerston, C.K, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Marber, M.S, Knapp, S, Structural Genomics Consortium (SGC) | | Deposit date: | 2013-07-13 | | Release date: | 2013-08-21 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.049 Å) | | Cite: | Mechanism and consequence of the autoactivation of p38 alpha mitogen-activated protein kinase promoted by TAB1.
Nat.Struct.Mol.Biol., 20, 2013
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