Author results

1K5I
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NMR STRUCTURE OF A RIBOSOMAL RNA HAIRPIN CONTAINING A CONSERVED CUCAA PENTALOOP
分子名称:5'-R(P*GP*GP*AP*CP*CP*CP*GP*GP*GP*CP*UP*CP*AP*AP*CP*CP*UP*GP*GP*GP*UP*CP*C)-3'
著者Nagaswamy, U., Gao, X., Martinis, S.A., Fox, G.E.
登録日2001-10-10
公開日2001-10-17
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献NMR structure of a ribosomal RNA hairpin containing a conserved CUCAA pentaloop.
Nucleic Acids Res., 29, 2001
2V0C
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LEUCYL-TRNA SYNTHETASE FROM THERMUS THERMOPHILUS COMPLEXED WITH A SULPHAMOYL ANALOGUE OF LEUCYL-ADENYLATE IN THE SYNTHETIC SITE AND AN ADDUCT OF AMP WITH 5-FLUORO-1,3-DIHYDRO-1-HYDROXY-2,1-BENZOXABOROLE (AN2690) IN THE EDITING SITE
分子名称:AMINOACYL-TRNA SYNTHETASE, LEUCINE, [(2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXYTETRAHYDRO-2-FURANYL]METHYL SULFAMATE, ...
著者Rock, F., Mao, W., Yaremchuk, A., Tukalo, M., Crepin, T., Zhou, H., Zhang, Y., Hernandez, V., Akama, T., Baker, S., Plattner, J., Shapiro, L., Martinis, S.A., Benkovic, S.J., Cusack, S., Alley, M.R.K.
登録日2007-05-14
公開日2007-07-03
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献An Antifungal Agent Inhibits an Aminoacyl-tRNA Synthetase by Trapping tRNA in the Editing Site.
Science, 316, 2007
2V0G
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LEUCYL-TRNA SYNTHETASE FROM THERMUS THERMOPHILUS COMPLEXED WITH A TRNA(LEU) TRANSCRIPT WITH 5-FLUORO-1,3-DIHYDRO-1-HYDROXY-2,1- BENZOXABOROLE (AN2690) FORMING AN ADDUCT TO THE RIBOSE OF ADENOSINE- 76 IN THE ENZYME EDITING SITE.
分子名称:AMINOACYL-TRNA SYNTHETASE, TRNALEU, LEUCINE, ...
著者Rock, F., Mao, W., Yaremchuk, A., Tukalo, M., Crepin, T., Zhou, H., Zhang, Y., Hernandez, V., Akama, T., Baker, S., Plattner, J., Shapiro, L., Martinis, S.A., Benkovic, S.J., Cusack, S., Alley, M.R.K.
登録日2007-05-14
公開日2007-07-03
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献An Antifungal Agent Inhibits an Aminoacyl-tRNA Synthetase by Trapping tRNA in the Editing Site.
Science, 316, 2007
3ZIU
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CRYSTAL STRUCTURE OF MYCOPLASMA MOBILE LEUCYL-TRNA SYNTHETASE WITH LEU-AMS IN THE ACTIVE SITE
分子名称:LEUCYL-TRNA SYNTHETASE, 5'-O-(L-leucylsulfamoyl)adenosine, GLYCEROL
著者Li, L., Palencia, A., Lukk, T., Li, Z., Luthey-Schulten, Z.A., Cusack, S., Martinis, S.A., Boniecki, M.T.
登録日2013-01-10
公開日2013-02-27
最終更新日2013-03-20
実験手法X-RAY DIFFRACTION (2.07 Å)
主引用文献Leucyl-tRNA Synthetase Editing Domain Functions as a Molecular Rheostat to Control Codon Ambiguity in Mycoplasma Pathogens.
Proc.Natl.Acad.Sci.USA, 110, 2013
4AQ7
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TERNARY COMPLEX OF E. COLI LEUCYL-TRNA SYNTHETASE, TRNA(LEU) AND LEUCYL-ADENYLATE ANALOGUE IN THE AMINOACYLATION CONFORMATION
分子名称:LEUCINE--TRNA LIGASE, E. COLI TRNALEU UAA ISOACCEPTOR, ZINC ION, ...
著者Palencia, A., Crepin, T., Vu, M.T., Lincecum Jr, T.L., Martinis, S.A., Cusack, S.
登録日2012-04-13
公開日2012-06-13
最終更新日2012-10-31
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural Dynamics of the Aminoacylation and Proofreading Functional Cycle of Bacterial Leucyl-tRNA Synthetase
Nat.Struct.Mol.Biol., 19, 2012
4ARC
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TERNARY COMPLEX OF E. COLI LEUCYL-TRNA SYNTHETASE, TRNA(LEU) AND LEUCINE IN THE EDITING CONFORMATION
分子名称:LEUCINE--TRNA LIGASE, TRNA-LEU5 (UAA ISOACCEPTOR), LEUCINE, ...
著者Palencia, A., Crepin, T., Vu, M.T., Lincecum Jr, T.L., Martinis, S.A., Cusack, S.
登録日2012-04-23
公開日2012-06-13
最終更新日2012-07-25
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural Dynamics of the Aminoacylation and Proofreading Functional Cycle of Bacterial Leucyl-tRNA Synthetase
Nat.Struct.Mol.Biol., 19, 2012
4ARI
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TERNARY COMPLEX OF E. COLI LEUCYL-TRNA SYNTHETASE, TRNA(LEU) AND THE BENZOXABOROLE AN2679 IN THE EDITING CONFORMATION
分子名称:LEUCINE--TRNA LIGASE, TRNA-LEU5 (UAA ISOACEPTOR), GLYCEROL, ...
著者Palencia, A., Crepin, T., Vu, M.T., Lincecum Jr, T.L., Martinis, S.A., Cusack, S.
登録日2012-04-24
公開日2012-06-13
最終更新日2019-05-15
実験手法X-RAY DIFFRACTION (2.08 Å)
主引用文献Structural Dynamics of the Aminoacylation and Proofreading Functional Cycle of Bacterial Leucyl-tRNA Synthetase
Nat.Struct.Mol.Biol., 19, 2012
4AS1
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TERNARY COMPLEX OF E. COLI LEUCYL-TRNA SYNTHETASE, TRNA(LEU) AND THE BENZOXABOROLE AN2679 IN THE EDITING CONFORMATION
分子名称:LEUCINE--TRNA LIGASE, TRNA-LEU5 (UAA ISOACEPTOR), MAGNESIUM ION
著者Palencia, A., Crepin, T., Vu, M.T., Lincecum Jr, T.L., Martinis, S.A., Cusack, S.
登録日2012-04-27
公開日2012-06-13
最終更新日2019-05-15
実験手法X-RAY DIFFRACTION (2.02 Å)
主引用文献Structural Dynamics of the Aminoacylation and Proofreading Functional Cycle of Bacterial Leucyl-tRNA Synthetase
Nat.Struct.Mol.Biol., 19, 2012
5AGH
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CRYSTAL STRUCTURE OF THE LEURS EDITING DOMAIN OF CANDIDA ALBICANS MUTANT K510A
分子名称:POTENTIAL CYTOSOLIC LEUCYL TRNA SYNTHETASE, ACETATE ION
著者Zhao, H., Palencia, A., Seiradake, E., Ghaemi, Z., Luthey-Schulten, Z., Cusack, S., Martinis, S.A.
登録日2015-02-02
公開日2015-07-01
最終更新日2015-10-28
実験手法X-RAY DIFFRACTION (1.81 Å)
主引用文献Analysis of the Resistance Mechanism of a Benzoxaborole Inhibitor Reveals Insight Into the Leucyl-tRNA Synthetase Editing Mechanism.
Acs Chem.Biol., 10, 2015
5AGI
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CRYSTAL STRUCTURE OF THE LEURS EDITING DOMAIN OF CANDIDA ALBICANS MUTANT K510A IN COMPLEX WITH THE ADDUCT FORMED BY AN2690-AMP
分子名称:POTENTIAL CYTOSOLIC LEUCYL TRNA SYNTHETASE, [(6-AMINO-9H-PURIN-9-YL)-[5-FLUORO-1,3-DIHYDRO-1-HYDROXY-2,1-BENZOXABOROLE]-4'YL]METHYL DIHYDROGEN PHOSPHATE, GLYCEROL
著者Zhao, H., Palencia, A., Seiradake, E., Ghaemi, Z., Luthey-Schulten, Z., Cusack, S., Martinis, S.A.
登録日2015-02-02
公開日2015-07-01
最終更新日2015-10-28
実験手法X-RAY DIFFRACTION (1.47 Å)
主引用文献Analysis of the Resistance Mechanism of a Benzoxaborole Inhibitor Reveals Insight Into the Leucyl-tRNA Synthetase Editing Mechanism.
Acs Chem.Biol., 10, 2015
5AGJ
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CRYSTAL STRUCTURE OF THE LEURS EDITING DOMAIN OF CANDIDA ALBICANS IN COMPLEX WITH THE ADDUCT AN2690-AMP
分子名称:POTENTIAL CYTOSOLIC LEUCYL TRNA SYNTHETASE, [(6-AMINO-9H-PURIN-9-YL)-[5-FLUORO-1,3-DIHYDRO-1-HYDROXY-2,1-BENZOXABOROLE]-4'YL]METHYL DIHYDROGEN PHOSPHATE
著者Zhao, H., Palencia, A., Seiradake, E., Ghaemi, Z., Luthey-Schulten, Z., Cusack, S., Martinis, S.A.
登録日2015-02-02
公開日2015-07-01
最終更新日2015-10-28
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Analysis of the Resistance Mechanism of a Benzoxaborole Inhibitor Reveals Insight Into the Leucyl-tRNA Synthetase Editing Mechanism.
Acs Chem.Biol., 10, 2015
2CP4
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CRYSTAL STRUCTURE OF THE CYTOCHROME P450-CAM ACTIVE SITE MUTANT THR252ALA
分子名称:CYTOCHROME P450-CAM, PROTOPORPHYRIN IX CONTAINING FE, CAMPHOR
著者Raag, R., Poulos, T.L.
登録日1991-06-04
公開日1993-01-15
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of the cytochrome P-450CAM active site mutant Thr252Ala.
Biochemistry, 30, 1991
3CP4
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CRYSTAL STRUCTURE OF THE CYTOCHROME P450-CAM ACTIVE SITE MUTANT THR252ALA
分子名称:CYTOCHROME P450-CAM, PROTOPORPHYRIN IX CONTAINING FE, ADAMANTANE
著者Raag, R., Poulos, T.L.
登録日1991-06-04
公開日1993-01-15
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of the cytochrome P-450CAM active site mutant Thr252Ala.
Biochemistry, 30, 1991
4CP4
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CRYSTAL STRUCTURE OF THE CYTOCHROME P450-CAM ACTIVE SITE MUTANT THR252ALA
分子名称:CYTOCHROME P450-CAM, PROTOPORPHYRIN IX CONTAINING FE, CAMPHOR
著者Raag, R., Poulos, T.L.
登録日1991-06-04
公開日1993-01-15
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of the cytochrome P-450CAM active site mutant Thr252Ala.
Biochemistry, 30, 1991