Author results

2CE0
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STRUCTURE OF OXIDIZED ARABIDOPSIS THALIANA CYTOCHROME 6A
Descriptor:CYTOCHROME C6, HEME C
Authors:Marcaida, M.J., Schlarb-Ridley, B.G., Worrall, J.A.R., Wastl, J., Evans, T.J., Bendall, D.S., Luisi, B.F., Howe, C.J.
Deposit date:2006-02-01
Release date:2006-07-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.24 Å)
Cite:Structure of Cytochrome C(6A), a Novel Dithio-Cytochrome of Arabidopsis Thaliana, and its Reactivity with Plastocyanin: Implications for Function.
J.Mol.Biol., 360, 2006
2CE1
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STRUCTURE OF REDUCED ARABIDOPSIS THALIANA CYTOCHROME 6A
Descriptor:CYTOCHROME C6, HEME C
Authors:Marcaida, M.J., Schlarb-Ridley, B.G., Worrall, J.A.R., Wastl, J., Evans, T.J., Bendall, D.S., Luisi, B.F., Howe, C.J.
Deposit date:2006-02-02
Release date:2006-07-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structure of Cytochrome C(6A), a Novel Dithio-Cytochrome of Arabidopsis Thaliana, and its Reactivity with Plastocyanin: Implications for Function.
J.Mol.Biol., 360, 2006
2V07
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STRUCTURE OF THE ARABIDOPSIS THALIANA CYTOCHROME C6A V52Q VARIANT
Descriptor:CYTOCHROME C6, HEME C
Authors:Worrall, J.A.R., Schlarb-Ridley, B.G., Reda, T., Marcaida, M.J., Moorlen, R.J., Wastl, J., Hirst, J., Bendall, D.S., Luisi, B.F., Howe, C.J.
Deposit date:2007-05-09
Release date:2007-07-24
Last modified:2019-01-23
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Modulation of heme redox potential in the cytochrome c6 family.
J. Am. Chem. Soc., 129, 2007
4OMJ
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CRYSTAL STRUCTURE OF SPF BOUND TO 2,3-OXIDOSQUALENE
Descriptor:SEC14-like protein 2, SULFATE ION, CHLORIDE ION, ...
Authors:Christen, M., Marcaida, M.J., Lamprakis, C., Cascella, M., Stocker, A.
Deposit date:2014-01-27
Release date:2015-04-15
Last modified:2015-06-24
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural insights on cholesterol endosynthesis: Binding of squalene and 2,3-oxidosqualene to supernatant protein factor.
J.Struct.Biol., 190, 2015
4OMK
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CRYSTAL STRUCTURE OF SPF BOUND TO SQUALENE
Descriptor:SEC14-like protein 2, SULFATE ION, CHLORIDE ION, ...
Authors:Christen, M., Marcaida, M.J., Lamprakis, C., Cascella, M., Stocker, A.
Deposit date:2014-01-27
Release date:2015-04-15
Last modified:2015-06-24
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural insights on cholesterol endosynthesis: Binding of squalene and 2,3-oxidosqualene to supernatant protein factor.
J.Struct.Biol., 190, 2015
2VNF
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MOLECULAR BASIS OF HISTONE H3K4ME3 RECOGNITION BY ING4
Descriptor:INHIBITOR OF GROWTH PROTEIN 4, HISTONE H3, SODIUM ION, ...
Authors:Palacios, A., Munoz, I.G., Pantoja-Uceda, D., Marcaida, M.J., Torres, D., Martin-Garcia, J.M., Luque, I., Montoya, G., Blanco, F.J.
Deposit date:2008-02-04
Release date:2008-04-01
Last modified:2016-12-28
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Molecular Basis of Histone H3K4Me3 Recognition by Ing4
J.Biol.Chem., 283, 2008
2V08
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STRUCTURE OF WILD-TYPE PHORMIDIUM LAMINOSUM CYTOCHROME C6
Descriptor:CYTOCHROME C6, HEME C, IMIDAZOLE, ...
Authors:Worrall, J.A.R., Schlarb-Ridley, B.G., Reda, T., Marcaida, M.J., Moorlen, R.J., Wastl, J., Hirst, J., Bendall, D.S., Luisi, B.F., Howe, C.J.
Deposit date:2007-05-10
Release date:2007-07-24
Last modified:2019-01-23
Method:X-RAY DIFFRACTION (2 Å)
Cite:Modulation of heme redox potential in the cytochrome c6 family.
J. Am. Chem. Soc., 129, 2007
2VS7
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THE CRYSTAL STRUCTURE OF I-DMOI IN COMPLEX WITH DNA AND CA
Descriptor:HOMING ENDONUCLEASE I-DMOI, 5'-D(*GP*CP*CP*TP*TP*GP*CP*CP*GP*GP *GP*TP*AP*AP*GP*TP*TP*CP*CP*GP*GP*CP*GP*CP*G)-3', 5'-D(*CP*GP*CP*GP*CP*CP*GP*GP*AP*AP *CP*TP*TP*AP*CP*CP*CP*GP*GP*CP*AP*AP*GP*GP*C)-3', ...
Authors:Marcaida, M.J., Prieto, J., Redondo, P., Nadra, A.D., Alibes, A., Serrano, L., Grizot, S., Duchateau, P., Paques, F., Blanco, F.J., Montoya, G.
Deposit date:2008-04-21
Release date:2008-11-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Crystal Structure of I-Dmoi in Complex with its Target DNA Provides New Insights Into Meganuclease Engineering.
Proc.Natl.Acad.Sci.USA, 105, 2008
2VS8
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THE CRYSTAL STRUCTURE OF I-DMOI IN COMPLEX WITH DNA AND MN
Descriptor:HOMING ENDONUCLEASE I-DMOI, 5'-D(*GP*CP*CP*TP*TP*GP*CP*CP*GP*GP *GP*TP*AP*A)-3', 5'-D(*GP*TP*TP*CP*CP*GP*GP*CP* DGP*DCP*DGP)-3', ...
Authors:Marcaida, M.J., Prieto, J., Redondo, P., Nadra, A.D., Alibes, A., Serrano, L., Grizot, S., Duchateau, P., Paques, F., Blanco, F.J., Montoya, G.
Deposit date:2008-04-21
Release date:2008-11-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal Structure of I-Dmoi in Complex with its Target DNA Provides New Insights Into Meganuclease Engineering.
Proc.Natl.Acad.Sci.USA, 105, 2008
4D6O
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THE CRYSTAL STRUCTURE OF I-DMOI IN COMPLEX WITH ITS TARGET DNA AT 1H INCUBATION IN 5MM MG (STATE 2)
Descriptor:HOMING ENDONUCLEASE I-DMOI, 25MER, MAGNESIUM ION, ...
Authors:Molina, R., Stella, S., Redondo, P., Gomez, H., Marcaida, M.J., Orozco, M., Prieto, J., Montoya, G.
Deposit date:2014-11-13
Release date:2014-12-17
Last modified:2017-08-23
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Visualizing Phosphodiester-Bond Hydrolysis by an Endonuclease.
Nat.Struct.Mol.Biol., 22, 2015
5O6I
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STRUCTURES AND DYNAMICS OF MESOPHILIC VARIANTS FROM THE HOMING ENDONUCLEASE I-DMOI
Descriptor:Homing endonuclease I-DmoI, DNA (25-MER), MANGANESE (II) ION, ...
Authors:Molina, R., Marcaida, M.J.
Deposit date:2017-06-06
Release date:2017-12-06
Last modified:2018-01-03
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structure and dynamics of mesophilic variants from the homing endonuclease I-DmoI.
J. Comput. Aided Mol. Des., 31, 2017
4UNA
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THE CRYSTAL STRUCTURE OF I-DMOI IN COMPLEX WITH ITS TARGET DNA AT 2 DAYS INCUBATION IN 5MM MN (STATE 4)
Descriptor:HOMING ENDONUCLEASE I-DMOI, 25MER, 5'-D(*CP*GP*CP*GP*CP*CP*GP*GP*AP*AP*CP*TP*TP*AP*C)-3', ...
Authors:Molina, R., Stella, S., Redondo, P., Gomez, H., Marcaida, M.J., Orozco, M., Prieto, J., Montoya, G.
Deposit date:2014-05-26
Release date:2014-12-17
Last modified:2015-01-21
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Visualizing Phosphodiester-Bond Hydrolysis by an Endonuclease.
Nat.Struct.Mol.Biol., 22, 2015
4UNC
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THE CRYSTAL STRUCTURE OF I-DMOI IN COMPLEX WITH ITS TARGET DNA AT 8 DAYS INCUBATION IN 5MM MN (STATE 6)
Descriptor:HOMING ENDONUCLEASE I-DMOI, 5'-D(*GP*CP*CP*TP*TP*GP*CP*CP*GP*GP*GP*TP*AP*A)-3', 5'-D(*CP*GP*CP*GP*CP*CP*GP*GP*AP*AP*CP*TP*TP*AP*C)-3', ...
Authors:Molina, R., Stella, S., Redondo, P., Gomez, H., Marcaida, M.J., Orozco, M., Prieto, J., Montoya, G.
Deposit date:2014-05-26
Release date:2014-12-17
Last modified:2015-01-21
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Visualizing Phosphodiester-Bond Hydrolysis by an Endonuclease.
Nat.Struct.Mol.Biol., 22, 2015
4D6N
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THE CRYSTAL STRUCTURE OF I-DMOI IN COMPLEX WITH ITS TARGET DNA AT 10 DAYS INCUBATION IN 5MM MG (STATE 7)
Descriptor:HOMING ENDONUCLEASE I-DMOI, 5'-D(*DGP*CP*CP*TP*TP*GP*CP*CP*GP*GP*GP*TP*AP*DAP)-3', 5'-D(*DGP*TP*TP*CP*CP*GP*GP*CP*GP*CP*GP)-3', ...
Authors:Molina, R., Stella, S., Redondo, P., Gomez, H., Marcaida, M.J., Orozco, M., Prieto, J., Montoya, G.
Deposit date:2014-11-13
Release date:2014-12-17
Last modified:2017-08-23
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Visualizing Phosphodiester-Bond Hydrolysis by an Endonuclease.
Nat.Struct.Mol.Biol., 22, 2015
4UT0
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THE CRYSTAL STRUCTURE OF I-DMOI IN COMPLEX WITH ITS TARGET DNA AT 10 DAYS INCUBATION IN 5MM MN (STATE 7)
Descriptor:HOMING ENDONUCLEASE I-DMOI, 5'-D(*GP*CP*CP*TP*TP*GP*CP*CP*GP*GP*GP*TP*AP*AP)-3', 5'-D(*GP*TP*TP*CP*CP*GP*GP*CP*GP*CP*GP)-3', ...
Authors:Molina, R., Stella, S., Redondo, P., Gomez, H., Marcaida, M.J., Orozco, M., Prieto, J., Montoya, G.
Deposit date:2014-07-17
Release date:2014-12-17
Last modified:2015-01-21
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Visualizing Phosphodiester-Bond Hydrolysis by an Endonuclease.
Nat.Struct.Mol.Biol., 22, 2015
5AKM
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THE CRYSTAL STRUCTURE OF I-DMOI G20S IN COMPLEX WITH ITS TARGET DNA IN THE PRESENCE OF 2MM MG
Descriptor:HOMING ENDONUCLEASE I-DMOI, 5'-D(*GP*CP*CP*TP*TP*GP*CP*CP*GP*GP*GP*TP*AP*AP)-3', 5'-D(*GP*TP*TP*CP*CP*GP*GP*CP*GP*CP*GP)-3', ...
Authors:Molina, R., Marcaida, M.J., Redondo, P., Marenchino, M., D'Abramo, M., Montoya, G., Prieto, J.
Deposit date:2015-03-04
Release date:2015-06-17
Last modified:2017-08-23
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Engineering a Nickase on the Homing Endonuclease I-Dmoi Scaffold.
J.Biol.Chem., 290, 2015
5AKF
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THE CRYSTAL STRUCTURE OF I-DMOI Q42AK120M IN COMPLEX WITH ITS TARGET DNA NICKED IN THE CODING STRAND A AND IN THE PRESENCE OF 2MM MN
Descriptor:HOMING ENDONUCLEASE I-DMOI, 5'-D(*GP*CP*CP*TP*TP*GP*CP*CP*GP*GP*GP*TP*AP*AP)-3', 5'-D(*GP*TP*TP*CP*CP*GP*GP*CP*GP*CP*GP)-3', ...
Authors:Molina, R., Marcaida, M.J., Redondo, P., Marenchino, M., D'Abramo, M., Montoya, G., Prieto, J.
Deposit date:2015-03-03
Release date:2015-06-17
Last modified:2017-08-23
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Engineering a Nickase on the Homing Endonuclease I-Dmoi Scaffold.
J.Biol.Chem., 290, 2015
4UNB
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THE CRYSTAL STRUCTURE OF I-DMOI IN COMPLEX WITH ITS TARGET DNA AT 6 DAYS INCUBATION IN 5MM MN (STATE 5)
Descriptor:HOMING ENDONUCLEASE I-DMOI, 5'-D(*GP*CP*CP*TP*TP*GP*CP*CP*GP*GP*GP*TP*AP*A)-3', 5'-D(*CP*GP*CP*GP*CP*CP*GP*GP*AP*AP*CP*TP*TP*AP*C)-3', ...
Authors:Molina, R., Stella, S., Redondo, P., Gomez, H., Marcaida, M.J., Orozco, M., Prieto, J., Montoya, G.
Deposit date:2014-05-26
Release date:2014-12-17
Last modified:2015-01-21
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Visualizing Phosphodiester-Bond Hydrolysis by an Endonuclease.
Nat.Struct.Mol.Biol., 22, 2015
4UN8
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THE CRYSTAL STRUCTURE OF I-DMOI IN COMPLEX WITH ITS TARGET DNA AT 1H INCUBATION IN 5MM MN (STATE 2)
Descriptor:HOMING ENDONUCLEASE I-DMOI, 25MER, MANGANESE (II) ION
Authors:Molina, R., Stella, S., Redondo, P., Gomez, H., Marcaida, M.J., Orozco, M., Prieto, J., Montoya, G.
Deposit date:2014-05-26
Release date:2014-12-17
Last modified:2015-01-21
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Visualizing Phosphodiester-Bond Hydrolysis by an Endonuclease.
Nat.Struct.Mol.Biol., 22, 2015
5AK9
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THE CRYSTAL STRUCTURE OF I-DMOI Q42AK120M IN COMPLEX WITH ITS TARGET DNA IN THE PRESENCE OF 2MM MN
Descriptor:HOMING ENDONUCLEASE I-DMOI, 5'-D(*GP*CP*CP*TP*TP*GP*CP*CP*GP*GP*GP*TP*AP*AP)-3', 5'-D(*GP*TP*TP*CP*CP*GP*GP*CP*GP*CP*GP)-3, ...
Authors:Molina, R., Marcaida, M.J., Redondo, P., Marenchino, M., D'Abramo, M., Montoya, G., Prieto, J.
Deposit date:2015-03-02
Release date:2015-06-17
Last modified:2017-08-23
Method:X-RAY DIFFRACTION (2.601 Å)
Cite:Engineering a Nickase on the Homing Endonuclease I-Dmoi Scaffold.
J.Biol.Chem., 290, 2015
4UN7
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THE CRYSTAL STRUCTURE OF I-DMOI IN COMPLEX WITH ITS TARGET DNA BEFORE INCUBATION IN 5MM MN (STATE 1)
Descriptor:HOMING ENDONUCLEASE I-DMOI, 25MER, ZINC ION
Authors:Molina, R., Stella, S., Redondo, P., Gomez, H., Marcaida, M.J., Orozco, M., Prieto, J., Montoya, G.
Deposit date:2014-05-26
Release date:2014-12-03
Last modified:2015-01-21
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Visualizing Phosphodiester-Bond Hydrolysis by an Endonuclease.
Nat.Struct.Mol.Biol., 22, 2015
4UN9
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THE CRYSTAL STRUCTURE OF I-DMOI IN COMPLEX WITH ITS TARGET DNA AT 8H INCUBATION IN 5MM MN (STATE 3)
Descriptor:HOMING ENDONUCLEASE I-DMOI, 25MER, MANGANESE (II) ION
Authors:Molina, R., Stella, S., Redondo, P., Gomez, H., Marcaida, M.J., Orozco, M., Prieto, J., Montoya, G.
Deposit date:2014-05-26
Release date:2015-01-14
Last modified:2015-07-22
Method:X-RAY DIFFRACTION (2.734 Å)
Cite:Visualizing Phosphodiester-Bond Hydrolysis by an Endonuclease.
Nat.Struct.Mol.Biol., 22, 2015
5AKN
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THE CRYSTAL STRUCTURE OF I-DMOI Q42AK120M IN COMPLEX WITH ITS TARGET DNA NICKED IN THE NON-CODING STRAND B AND IN THE PRESENCE OF 2MM MN
Descriptor:HOMING ENDONUCLEASE I-DMOI, 5'-D(*GP*CP*CP*TP*TP*GP*CP*CP*GP*GP*GP*TP*AP*AP)-3', 5'-D(*GP*TP*TP*CP*CP*GP*GP*CP*GP*CP*GP)-3, ...
Authors:Molina, R., Marcaida, M.J., Redondo, P., Marenchino, M., D'Abramo, M., Montoya, G., Prieto, J.
Deposit date:2015-03-04
Release date:2015-06-17
Last modified:2015-08-05
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Engineering a Nickase on the Homing Endonuclease I-Dmoi Scaffold.
J.Biol.Chem., 290, 2015
5O6G
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STRUCTURES AND DYNAMICS OF MESOPHILIC VARIANTS FROM THE HOMING ENDONUCLEASE I-DMOI
Descriptor:Homing endonuclease I-DmoI, DNA (25-MER), MANGANESE (II) ION, ...
Authors:Molina, R., Marcaida, M.J.
Deposit date:2017-06-06
Release date:2017-12-06
Last modified:2018-01-03
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Structure and dynamics of mesophilic variants from the homing endonuclease I-DmoI.
J. Comput. Aided Mol. Des., 31, 2017
4ZTQ
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HUMAN AURORA A CATALYTIC DOMAIN BOUND TO FK932
Descriptor:Aurora kinase A, (2Z,5Z)-2-[(4-ethylphenyl)imino]-3-(2-methoxyethyl)-5-(pyridin-4-ylmethylidene)-1,3-thiazolidin-4-one, (4S)-2-METHYL-2,4-PENTANEDIOL
Authors:Marcaida, M.J., Kilchmann, F., Schick, T., Reymond, J.L.
Deposit date:2015-05-14
Release date:2016-07-20
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Discovery of a Selective Aurora A Kinase Inhibitor by Virtual Screening.
J.Med.Chem., 59, 2016
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