Author results

5T3E
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CRYSTAL STRUCTURE OF A NONRIBOSOMAL PEPTIDE SYNTHETASE HETEROCYCLIZATION DOMAIN.
Descriptor:Bacillamide synthetase heterocyclization domain, SULFATE ION
Authors:Bloudoff, K., Schmeing, T.M.
Deposit date:2016-08-25
Release date:2016-11-02
Last modified:2017-01-11
Method:X-RAY DIFFRACTION (2.297 Å)
Cite:Structural and mutational analysis of the nonribosomal peptide synthetase heterocyclization domain provides insight into catalysis.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5OQZ
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CRYSTAL STRUCTURE OF THE LASSO PEPTIDE RUBRIVINODIN
Descriptor:Rubrivinodin
Authors:Fage, C.D., Hegemann, J.D., Marahiel, M.A.
Deposit date:2017-08-14
Release date:2018-02-07
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (0.806 Å)
Cite:General rules of fragmentation evidencing lasso structures in CID and ETD.
Analyst, 143, 2018
5M6P
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CRYSTAL STRUCTURE OF THE EPIMERIZATION DOMAIN FROM MODULE 3 OF TYROCIDINE SYNTHETASE B, TYCB3(E)
Descriptor:Tyrocidine synthase 2
Authors:Fage, C.D., Marahiel, M.A.
Deposit date:2016-10-25
Release date:2017-12-20
Last modified:2018-05-23
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Communication Breakdown: Dissecting the COM Interfaces between the Subunits of Nonribosomal Peptide Synthetases
To Be Published
5JRL
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CRYSTAL STRUCTURE OF THE SPHINGOPYXIN I LASSO PEPTIDE ISOPEPTIDASE SPI-ISOP (NATIVE)
Descriptor:Dipeptidyl aminopeptidases/acylaminoacyl-peptidases-like protein
Authors:Fage, C.D., Hegemann, J.D., Bange, G., Marahiel, M.A.
Deposit date:2016-05-06
Release date:2016-09-14
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structure and Mechanism of the Sphingopyxin I Lasso Peptide Isopeptidase.
Angew.Chem.Int.Ed.Engl., 55, 2016
5JRK
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CRYSTAL STRUCTURE OF THE SPHINGOPYXIN I LASSO PEPTIDE ISOPEPTIDASE SPI-ISOP (SEMET-DERIVED)
Descriptor:Dipeptidyl aminopeptidases/acylaminoacyl-peptidases-like protein, BETA-D-GLUCOSE
Authors:Fage, C.D., Hegemann, J.D., Bange, G., Marahiel, M.A.
Deposit date:2016-05-06
Release date:2016-09-28
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure and Mechanism of the Sphingopyxin I Lasso Peptide Isopeptidase.
Angew.Chem.Int.Ed.Engl., 55, 2016
5JQF
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CRYSTAL STRUCTURE OF THE LASSO PEPTIDE SPHINGOPYXIN I (SPI)
Descriptor:Sphingopyxin I
Authors:Fage, C.D., Hegemann, J.D., Harms, K., Bange, G., Marahiel, M.A.
Deposit date:2016-05-04
Release date:2016-09-14
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (0.85 Å)
Cite:Structure and Mechanism of the Sphingopyxin I Lasso Peptide Isopeptidase.
Angew. Chem. Int. Ed. Engl., 55, 2016
5J8Q
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CRYSTAL STRUCTURE OF THE CYSTEINE DESULFURASE SUFS OF BACILLUS SUBTILIS
Descriptor:Cysteine desulfurase SufS, PYRIDOXAL-5'-PHOSPHATE, ALANINE
Authors:Altegoer, F., Bange, G.
Deposit date:2016-04-08
Release date:2016-07-27
Method:X-RAY DIFFRACTION (1.702 Å)
Cite:Crystal Structure of Bacillus subtilis Cysteine Desulfurase SufS and Its Dynamic Interaction with Frataxin and Scaffold Protein SufU.
Plos One, 11, 2016
5F2V
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CRYSTAL STRUCTURE OF THE SMALL ALARMONE SYNTHETHASE 1 FROM BACILLUS SUBTILIS BOUND TO AMPCPP
Descriptor:GTP pyrophosphokinase YjbM, DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, MAGNESIUM ION
Authors:Steinchen, W., Schuhmacher, J.S., Altegoer, F., Bange, G.
Deposit date:2015-12-02
Release date:2015-12-16
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Catalytic mechanism and allosteric regulation of an oligomeric (p)ppGpp synthetase by an alarmone.
Proc.Natl.Acad.Sci.USA, 112, 2015
5DKJ
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YEAST 20S PROTEASOME IN COMPLEX WITH OCTREOTIDE-PI
Descriptor:Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, Proteasome subunit alpha type-4, ...
Authors:Beck, P., Cui, H., Groll, M.
Deposit date:2015-09-03
Release date:2015-10-28
Last modified:2016-01-27
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Targeted Delivery of Proteasome Inhibitors to Somatostatin-Receptor-Expressing Cancer Cells by Octreotide Conjugation.
Chemmedchem, 10, 2015
5DKI
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YEAST 20S PROTEASOME IN COMPLEX WITH ALKYNE-PI
Descriptor:Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, Proteasome subunit alpha type-4, ...
Authors:Beck, P., Cui, H., Groll, M.
Deposit date:2015-09-03
Release date:2015-10-28
Last modified:2016-01-27
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Targeted Delivery of Proteasome Inhibitors to Somatostatin-Receptor-Expressing Cancer Cells by Octreotide Conjugation.
Chemmedchem, 10, 2015
5DED
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CRYSTAL STRUCTURE OF THE SMALL ALARMONE SYNTHETHASE 1 FROM BACILLUS SUBTILIS BOUND TO ITS PRODUCT PPPGPP
Descriptor:GTP pyrophosphokinase YjbM, guanosine 5'-(tetrahydrogen triphosphate) 3'-(trihydrogen diphosphate), MAGNESIUM ION
Authors:Steinchen, W., Schuhmacher, J.S., Altegoer, F., Bange, G.
Deposit date:2015-08-25
Release date:2015-10-28
Method:X-RAY DIFFRACTION (2.942 Å)
Cite:Catalytic mechanism and allosteric regulation of an oligomeric (p)ppGpp synthetase by an alarmone.
Proc.Natl.Acad.Sci.USA, 112, 2015
5DEC
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CRYSTAL STRUCTURE OF THE SMALL ALARMONE SYNTHETASE 1 FROM BACILLUS SUBTILIS
Descriptor:GTP pyrophosphokinase YjbM
Authors:Steinchen, W., Altegoer, A., Schuhmacher, J.S., Bange, G.
Deposit date:2015-08-25
Release date:2015-10-28
Last modified:2018-06-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Catalytic mechanism and allosteric regulation of an oligomeric (p)ppGpp synthetase by an alarmone.
Proc.Natl.Acad.Sci.USA, 112, 2015
5D9E
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CRYSTAL STRUCTURE OF THE PROLINE-RICH LASSO PEPTIDE CAULOSEGNIN II
Descriptor:Caulosegnin II, CHLORIDE ION
Authors:Fage, C.D., Hegemann, J.D., Harms, K., Marahiel, M.A.
Deposit date:2015-08-18
Release date:2016-02-17
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (0.859 Å)
Cite:The ring residue proline 8 is crucial for the thermal stability of the lasso peptide caulosegnin II.
Mol Biosyst, 12, 2016
4R1J
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CRYSTAL STRUCTURE OF ARC1P-C
Descriptor:GU4 nucleic-binding protein 1, GLYCEROL
Authors:Altegoer, F., Bange, G.
Deposit date:2014-08-06
Release date:2015-02-18
Last modified:2015-03-11
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:A Synthetic Adenylation-Domain-Based tRNA-Aminoacylation Catalyst.
Angew.Chem.Int.Ed.Engl., 54, 2015
4NAG
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XANTHOMONINS I III ARE A NEW CLASS OF LASSO PEPTIDES FEATURINGA SEVEN-MEMBERED MACROLACTAM RING
Descriptor:Xanthomonin I, HEXANE-1,6-DIOL
Authors:Hegemann, J.D., Zimmermann, M., Zhu, S., Steuber, H., Harms, K., Xie, X., Marahiel, M.A.
Deposit date:2013-10-22
Release date:2014-04-30
Last modified:2014-05-21
Method:X-RAY DIFFRACTION (0.81 Å)
Cite:Xanthomonins I-III: A New Class of Lasso Peptides with a Seven-Residue Macrolactam Ring.
Angew.Chem.Int.Ed.Engl., 53, 2014
4MRT
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STRUCTURE OF THE PHOSPHOPANTETHEINE TRANSFERASE SFP IN COMPLEX WITH COENZYME A AND A PEPTIDYL CARRIER PROTEIN
Descriptor:Tyrocidine synthase 3, 4'-phosphopantetheinyl transferase sfp, MAGNESIUM ION, ...
Authors:Tufar, P., Rahighi, S., Kraas, F.I., Kirchner, D.K., Loehr, F., Henrich, E., Koepke, J., Dikic, I., Guentert, P., Marahiel, M.A., Doetsch, V.
Deposit date:2013-09-17
Release date:2014-04-23
Last modified:2014-05-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structure of a PCP/Sfp Complex Reveals the Structural Basis for Carrier Protein Posttranslational Modification.
Chem.Biol., 21, 2014
3E7X
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CRYSTAL STRUCTURE OF DLTA: IMPLICATIONS FOR THE REACTION MECHANISM OF NON-RIBOSOMAL PEPTIDE SYNTHETASE (NRPS) ADENYLATION DOMAINS
Descriptor:D-alanine--poly(phosphoribitol) ligase subunit 1, ADENOSINE MONOPHOSPHATE
Authors:Yonus, H., Neumann, P., Zimmermann, S., May, J.J., Marahiel, M.A., Stubbs, M.T.
Deposit date:2008-08-19
Release date:2008-09-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of DltA. Implications for the reaction mechanism of non-ribosomal peptide synthetase adenylation domains
J.Biol.Chem., 283, 2008
3E7W
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CRYSTAL STRUCTURE OF DLTA: IMPLICATIONS FOR THE REACTION MECHANISM OF NON-RIBOSOMAL PEPTIDE SYNTHETASE (NRPS) ADENYLATION DOMAINS
Descriptor:D-alanine--poly(phosphoribitol) ligase subunit 1, PHOSPHATE ION, ADENOSINE MONOPHOSPHATE
Authors:Yonus, H., Neumann, P., Zimmermann, S., May, J.J., Marahiel, M.A., Stubbs, M.T.
Deposit date:2008-08-19
Release date:2008-09-09
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Crystal structure of DltA. Implications for the reaction mechanism of non-ribosomal peptide synthetase adenylation domains
J.Biol.Chem., 283, 2008
2XV1
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CRYSTAL STRUCTURE OF THE TRISCATECHOLATE SIDEROPHORE BINDING PROTEIN FEUA FROM BACILLUS SUBTILIS COMPLEXED WITH FERRIC MECAM
Descriptor:IRON-UPTAKE SYSTEM-BINDING PROTEIN, N,N',N''-[BENZENE-1,3,5-TRIYLTRIS(METHYLENE)]TRIS(2,3-DIHYDROXYBENZAMIDE), FE (III) ION, ...
Authors:Peuckert, F., Miethke, M., Schwoerer, C.J., Albrecht, A.G., Oberthuer, M., Marahiel, M.A.
Deposit date:2010-10-22
Release date:2011-08-10
Last modified:2012-03-28
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:The Siderophore Binding Protein Feua Shows Limited Promiscuity Toward Exogenous Triscatecholates
Chem.Biol., 18, 2011
2XUZ
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CRYSTAL STRUCTURE OF THE TRISCATECHOLATE SIDEROPHORE BINDING PROTEIN FEUA FROM BACILLUS SUBTILIS COMPLEXED WITH FERRI-ENTEROBACTIN
Descriptor:IRON-UPTAKE SYSTEM-BINDING PROTEIN, N,N',N''-[(3S,7S,11S)-2,6,10-trioxo-1,5,9-trioxacyclododecane-3,7,11-triyl]tris(2,3-dihydroxybenzamide), FE (III) ION, ...
Authors:Peuckert, F., Miethke, M., Schwoerer, C.J., Albrecht, A.G., Oberthuer, M., Marahiel, M.A.
Deposit date:2010-10-22
Release date:2011-08-10
Last modified:2012-03-28
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The Siderophore Binding Protein Feua Shows Limited Promiscuity Toward Exogenous Triscatecholates
Chem.Biol., 18, 2011
2XHG
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CRYSTAL STRUCTURE OF THE EPIMERIZATION DOMAIN FROM THE INITIATION MODULE OF TYROCIDINE BIOSYNTHESIS
Descriptor:TYROCIDINE SYNTHETASE A, GLYCEROL, SODIUM ION
Authors:Samel, S.-A., Heine, A., Marahiel, M.A., Essen, L.-O.
Deposit date:2010-06-15
Release date:2011-07-06
Last modified:2014-10-22
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structure of the Epimerization Domain of Tyrocidine Synthetase A
Acta Crystallogr.,Sect.D, 70, 2014
2WI8
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CRYSTAL STRUCTURE OF THE TRISCATECHOLATE SIDEROPHORE BINDING PROTEIN FEUA FROM BACILLUS SUBTILIS
Descriptor:IRON-UPTAKE SYSTEM-BINDING PROTEIN, CHLORIDE ION
Authors:Peuckert, F., Miethke, M., Albrecht, A.G., Essen, L.-O., Marahiel, M.A.
Deposit date:2009-05-08
Release date:2009-09-22
Last modified:2011-12-07
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Structural Basis and Stereochemistry of Triscatecholate Siderophore Binding by Feua.
Angew.Chem.Int.Ed.Engl., 48, 2009
2WHY
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CRYSTAL STRUCTURE OF THE TRISCATECHOLATE SIDEROPHORE BINDING PROTEIN FEUA FROM BACILLUS SUBTILIS COMPLEXED WITH FERRI-BACILLIBACTIN
Descriptor:IRON-UPTAKE SYSTEM-BINDING PROTEIN, BACILLIBACTIN, CHLORIDE ION, ...
Authors:Peuckert, F., Miethke, M., Albrecht, A.G., Essen, L.-O., Marahiel, M.A.
Deposit date:2009-05-07
Release date:2009-09-29
Last modified:2011-12-28
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural Basis and Stereochemistry of Triscatecholate Siderophore Binding by Feua.
Angew.Chem.Int.Ed.Engl., 48, 2009
2WBQ
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CRYSTAL STRUCTURE OF VIOC IN COMPLEX WITH (2S,3S)-HYDROXYARGININE
Descriptor:L-ARGININE BETA-HYDROXYLASE, ACETATE ION, (2S,3S)-3-HYDROXYARGININE
Authors:Helmetag, V., Samel, S.A., Thomas, M.G., Marahiel, M.A., Essen, L.-O.
Deposit date:2009-03-02
Release date:2009-06-23
Last modified:2013-05-08
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Structural Basis for the Erythro-Stereospecificity of the L-Arginine Oxygenase Vioc in Viomycin Biosynthesis.
FEBS J., 276, 2009
2WBP
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CRYSTAL STRUCTURE OF VIOC IN COMPLEX WITH FE(II), (2S,3S)- HYDROXYARGININE, AND SUCCINATE
Descriptor:L-ARGININE BETA-HYDROXYLASE, ARGININE, FE (II) ION, ...
Authors:Helmetag, V., Samel, S.A., Thomas, M.G., Marahiel, M.A., Essen, L.-O.
Deposit date:2009-03-02
Release date:2009-06-23
Last modified:2013-05-08
Method:X-RAY DIFFRACTION (1.16 Å)
Cite:Structural Basis for the Erythro-Stereospecificity of the L-Arginine Oxygenase Vioc in Viomycin Biosynthesis.
FEBS J., 276, 2009
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