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2WC0
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BU of 2wc0 by Molmil
crystal structure of human insulin degrading enzyme in complex with iodinated insulin
Descriptor: 1,4-DIETHYLENE DIOXIDE, INSULIN A CHAIN, INSULIN B CHAIN, ...
Authors:Manolopoulou, M, Guo, Q, Malito, E, Schilling, A.B, Tang, W.J.
Deposit date:2009-03-06
Release date:2009-03-24
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Molecular Basis of Catalytic Chamber-Assisted Unfolding and Cleavage of Human Insulin by Human Insulin Degrading Enzyme.
J.Biol.Chem., 284, 2009
2WBY
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BU of 2wby by Molmil
Crystal structure of human insulin-degrading enzyme in complex with insulin
Descriptor: INSULIN A CHAIN, INSULIN B CHAIN, INSULIN-DEGRADING ENZYME, ...
Authors:Manolopoulou, M, Guo, Q, Malito, E, Schilling, A.B, Tang, W.J.
Deposit date:2009-03-06
Release date:2009-03-24
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Molecular Basis of Catalytic Chamber-Assisted Unfolding and Cleavage of Human Insulin by Human Insulin Degrading Enzyme.
J.Biol.Chem., 284, 2009
3E4Z
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BU of 3e4z by Molmil
Crystal structure of human insulin degrading enzyme in complex with insulin-like growth factor II
Descriptor: Insulin-degrading enzyme, Insulin-like growth factor II, ZINC ION
Authors:Guo, Q, Manolopoulou, M, Tang, W.-J.
Deposit date:2008-08-12
Release date:2009-08-18
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Molecular Basis for the Recognition and Cleavages of IGF-II, TGF-alpha, and Amylin by Human Insulin-Degrading Enzyme.
J.Mol.Biol., 395, 2010
3E50
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BU of 3e50 by Molmil
Crystal structure of human insulin degrading enzyme in complex with transforming growth factor-alpha
Descriptor: Insulin-degrading enzyme, Protransforming growth factor alpha, ZINC ION
Authors:Guo, Q, Manolopoulou, M, Tang, W.-J.
Deposit date:2008-08-12
Release date:2009-08-18
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Molecular Basis for the Recognition and Cleavages of IGF-II, TGF-alpha, and Amylin by Human Insulin-Degrading Enzyme.
J.Mol.Biol., 395, 2010
3HGZ
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BU of 3hgz by Molmil
Crystal structure of human insulin-degrading enzyme in complex with amylin
Descriptor: Insulin-degrading enzyme, Islet amyloid polypeptide, ZINC ION
Authors:Guo, Q, Bian, Y, Tang, W.J.
Deposit date:2009-05-14
Release date:2009-12-08
Last modified:2021-10-13
Method:X-RAY DIFFRACTION (2.91 Å)
Cite:Molecular Basis for the Recognition and Cleavages of IGF-II, TGF-alpha, and Amylin by Human Insulin-Degrading Enzyme.
J.Mol.Biol., 395, 2010
2JG4
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BU of 2jg4 by Molmil
Substrate-free IDE structure in its closed conformation
Descriptor: 1,4-DIETHYLENE DIOXIDE, INSULIN DEGRADING ENZYME, ZINC ION
Authors:Malito, E, Tang, W.J.
Deposit date:2007-02-07
Release date:2007-07-03
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of Substrate-Free Human Insulin Degrading Enzyme (Ide) and Biophysical Analysis of ATP-Induced Conformational Switch of Ide
J.Biol.Chem., 282, 2007
2JBU
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BU of 2jbu by Molmil
Crystal structure of human insulin degrading enzyme complexed with co- purified peptides.
Descriptor: 1,4-DIETHYLENE DIOXIDE, CO-PURIFIED PEPTIDE, INSULIN-DEGRADING ENZYME
Authors:Im, H, Shen, Y, Tang, W.J.
Deposit date:2006-12-11
Release date:2007-07-03
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure of Substrate-Free Human Insulin Degrading Enzyme (Ide) and Biophysical Analysis of ATP-Induced Conformational Switch of Ide
J.Biol.Chem., 282, 2007
3E4A
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BU of 3e4a by Molmil
Human IDE-inhibitor complex at 2.6 angstrom resolution
Descriptor: 1,4-DIETHYLENE DIOXIDE, ACETIC ACID, HYDROXAMATE PEPTIDE II1, ...
Authors:Malito, E, Leissring, M.A, Choi, S, Cuny, G.D, Tang, W.J.
Deposit date:2008-08-11
Release date:2009-05-19
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Designed inhibitors of insulin-degrading enzyme regulate the catabolism and activity of insulin.
Plos One, 5, 2010
2WK3
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BU of 2wk3 by Molmil
Crystal structure of human insulin-degrading enzyme in complex with amyloid-beta (1-42)
Descriptor: BETA-AMYLOID PROTEIN 42, INSULIN DEGRADING ENZYME, ZINC ION
Authors:Guo, Q, Tang, W.J.
Deposit date:2009-06-05
Release date:2009-11-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:Molecular Basis for the Recognition and Cleavages of Igf-II, Tgf-Alpha, and Amylin by Human Insulin Degrading Enzyme.
J.Mol.Biol., 395, 2010
3CWW
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BU of 3cww by Molmil
Crystal Structure of IDE-bradykinin complex
Descriptor: 1,4-DIETHYLENE DIOXIDE, ACETATE ION, Insulin-degrading enzyme, ...
Authors:Malito, E, Tang, W.J.
Deposit date:2008-04-23
Release date:2008-11-25
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Molecular Bases for the Recognition of Short Peptide Substrates and Cysteine-Directed Modifications of Human Insulin-Degrading Enzyme
Biochemistry, 47, 2008

217705

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