Author results

3NF5
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CRYSTAL STRUCTURE OF THE C-TERMINAL DOMAIN OF NUCLEAR PORE COMPLEX COMPONENT NUP116 FROM CANDIDA GLABRATA
分子名称:Nucleoporin NUP116, GLYCEROL
著者Sampathkumar, P., Manglicmot, D., Bain, K., Gilmore, J., Gheyi, T., Rout, M., Sali, A., Atwell, S., Thompson, D.A., Emtage, J.S., Wasserman, S., Sauder, J.M., Burley, S.K., New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2010-06-09
公開日2010-08-04
最終更新日2018-11-21
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Atomic structure of the nuclear pore complex targeting domain of a Nup116 homologue from the yeast, Candida glabrata.
Proteins, 80, 2012
5VB9
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IL-17A IN COMPLEX WITH PEPTIDE
分子名称:Interleukin-17A, Peptide inhibitor, 1,2-ETHANEDIOL, ...
著者Antonysamy, S., Russell, M., Zhang, A., Groshong, C., Manglicmot, D., Lu, F., Benach, J., Wasserman, S.R., Zhang, F., Afshar, S., Bina, H., Broughton, H., Chalmers, M., Dodge, J., Espada, A., Jones, S., Ting, J.P., Woodman, M.
登録日2017-03-28
公開日2018-02-14
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Utilization of peptide phage display to investigate hotspots on IL-17A and what it means for drug discovery.
PLoS ONE, 13, 2018
6C2R
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AURORA A LIGAND COMPLEX
分子名称:Aurora kinase A, SULFATE ION, (2R,4R)-1-[(3-chloro-2-fluorophenyl)methyl]-4-({3-fluoro-6-[(5-methyl-1H-pyrazol-3-yl)amino]pyridin-2-yl}methyl)-2-methylpiperidine-4-carboxylic acid
著者Antonysamy, S., Pustilnik, A., Manglicmot, D., Froning, K., Weichert, K., Wasserman, S.
登録日2018-01-08
公開日2019-01-23
最終更新日2019-02-20
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献Aurora A Kinase Inhibition Is Synthetic Lethal with Loss of theRB1Tumor Suppressor Gene.
Cancer Discov, 9, 2019
6C2T
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AURORA A LIGAND COMPLEX
分子名称:Aurora kinase A, (2S,4R)-1-[(3-chloro-2-fluorophenyl)methyl]-2-methyl-4-({3-[(1,3-thiazol-2-yl)amino]isoquinolin-1-yl}methyl)piperidine-4-carboxylic acid, DIMETHYL SULFOXIDE, ...
著者Antonysamy, S., Pustilnik, A., Manglicmot, D., Froning, K., Weichert, K., Wasserman, S.
登録日2018-01-08
公開日2019-01-23
最終更新日2019-02-20
実験手法X-RAY DIFFRACTION (1.73 Å)
主引用文献Aurora A Kinase Inhibition Is Synthetic Lethal with Loss of theRB1Tumor Suppressor Gene.
Cancer Discov, 9, 2019
3N7C
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CRYSTAL STRUCTURE OF THE RAN BINDING DOMAIN FROM THE NUCLEAR PORE COMPLEX COMPONENT NUP2 FROM ASHBYA GOSSYPII
分子名称:ABR034Wp
著者Sampathkumar, P., Manglicmot, D., Gilmore, J., Bain, K., Gheyi, T., Atwell, S., Thompson, D.A., Emtage, J.S., Wasserman, S., Sauder, J.M., Burley, S.K., New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2010-05-26
公開日2010-06-16
最終更新日2018-11-21
実験手法X-RAY DIFFRACTION (2.26 Å)
主引用文献Crystal structure of the RAN binding domain from the nuclear pore complex component NUP2 from Ashbya gossypii
To be Published
5C9C
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CRYSTAL STRUCTURE OF BRAF(V600E) IN COMPLEX WITH LY3009120 COMPND
分子名称:Serine/threonine-protein kinase B-raf, 1-(3,3-dimethylbutyl)-3-{2-fluoro-4-methyl-5-[7-methyl-2-(methylamino)pyrido[2,3-d]pyrimidin-6-yl]phenyl}urea, CHLORIDE ION
著者Edwards, T., Abendroth, J., Chun, L.
登録日2015-06-26
公開日2015-07-15
最終更新日2015-10-14
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Inhibition of RAF Isoforms and Active Dimers by LY3009120 Leads to Anti-tumor Activities in RAS or BRAF Mutant Cancers.
Cancer Cell, 28, 2015