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CopA ATP Binding Domain
Descriptor:	cation-transporting ATPase
Authors:	Sazinsky, M.H, Mandal, A.K, Arguello, J.M, Rosenzweig, A.C.
Deposit date:	2005-10-06
Release date:	2006-01-03
Last modified:	2011-07-13
Method:	X-RAY DIFFRACTION (2.3 Å)
Cite:	Structure of the ATP binding domain from the Archaeoglobus fulgidus Cu+-ATPase. J.Biol.Chem., 281, 2006

Aurora A Kinase complexed with SCH 1473759
Descriptor:	2-{ethyl[(5-{[6-methyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]amino}isothiazol-3-yl)methyl]amino}-2-methylpropan-1-ol, Serine/threonine-protein kinase 6, TETRAETHYLENE GLYCOL
Authors:	Hruza, A, Prosis, W, Ramanathan, L.
Deposit date:	2010-05-10
Release date:	2010-07-21
Last modified:	2023-09-06
Method:	X-RAY DIFFRACTION (2.4 Å)
Cite:	Discovery of a Potent, Injectable Inhibitor of Aurora Kinases Based on the Imidazo-[1,2-a]-Pyrazine Core. ACS Med Chem Lett, 1, 2010

Imidazo[1,2-a]pyrazine-based Aurora Kinase Inhibitors
Descriptor:	N-(3-methylisothiazol-5-yl)-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine, Serine/threonine-protein kinase 6
Authors:	Hruza, A.
Deposit date:	2010-06-30
Release date:	2010-08-18
Last modified:	2023-09-06
Method:	X-RAY DIFFRACTION (3.05 Å)
Cite:	Discovery of imidazo[1,2-a]pyrazine-based Aurora kinase inhibitors. Bioorg.Med.Chem.Lett., 20, 2010