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6NJG
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UBIQUITIN VARIANT IN COMPLEX WITH UBIQUITIN INTERACTING MOTIF
分子名称:Vacuolar protein sorting-associated protein 27, Polyubiquitin-B
著者Manczyk, N., Sicheri, F.
登録日2019-01-03
公開日2019-03-06
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Dimerization of a ubiquitin variant leads to high affinity interactions with a ubiquitin interacting motif.
Protein Sci., 2019
6DGF
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UBIQUITIN VARIANT BOUND TO USP2
分子名称:Ubiquitin carboxyl-terminal hydrolase 2, Polyubiquitin-B, ZINC ION, ...
著者Manczyk, N., Sicheri, F.
登録日2018-05-17
公開日2019-02-13
実験手法X-RAY DIFFRACTION (2.34 Å)
主引用文献Yeast-Two-Hybrid is an Effective Platform for the Discovery of Novel Inhibitors of Human Deubiquitinases
To Be Published
6BVA
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UBIQUITIN VARIANT (UBV.FL10.1) BOUND TO A HUMAN SKP1-FBL10 FRAGMENT COMPLEX.
分子名称:S-phase kinase-associated protein 1, Lysine-specific demethylase 2B, Polyubiquitin-B
著者Manczyk, N., Sicheri, F.
登録日2017-12-12
公開日2018-07-18
最終更新日2018-09-19
実験手法X-RAY DIFFRACTION (2.66 Å)
主引用文献A Structure-Based Strategy for Engineering Selective Ubiquitin Variant Inhibitors of Skp1-Cul1-F-Box Ubiquitin Ligases.
Structure, 26, 2018
6BYH
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UBIQUITIN VARIANT (UBV.FL11.1) BOUND TO A HUMAN SKP1-FBL11 FRAGMENT COMPLEX.
分子名称:S-phase kinase-associated protein 1, Lysine-specific demethylase 2A, Polyubiquitin-B
著者Manczyk, N., Sicheri, F.
登録日2017-12-20
公開日2018-07-18
最終更新日2018-09-19
実験手法X-RAY DIFFRACTION (2.61 Å)
主引用文献A Structure-Based Strategy for Engineering Selective Ubiquitin Variant Inhibitors of Skp1-Cul1-F-Box Ubiquitin Ligases.
Structure, 26, 2018
6C16
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UBIQUITIN VARIANT (UBV.FBL10.1) BOUND TO A HUMAN SKP1-FBL11 FRAGMENT COMPLEX.
分子名称:S-phase kinase-associated protein 1, Lysine-specific demethylase 2A, Polyubiquitin-B
著者Manczyk, N., Sicheri, F.
登録日2018-01-04
公開日2018-07-18
最終更新日2018-09-19
実験手法X-RAY DIFFRACTION (3.27 Å)
主引用文献A Structure-Based Strategy for Engineering Selective Ubiquitin Variant Inhibitors of Skp1-Cul1-F-Box Ubiquitin Ligases.
Structure, 26, 2018
2LWR
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SOLUTION STRUCTURE OF RING2 DOMAIN FROM PARKIN
分子名称:SD01679p, ZINC ION
著者Mercier, P., Spratt, D.E., Manczyk, N., Shaw, G.S.
登録日2012-08-06
公開日2013-06-12
最終更新日2014-10-15
実験手法SOLUTION NMR
主引用文献A molecular explanation for the recessive nature of parkin-linked Parkinson's disease.
Nat Commun, 4, 2013
2M48
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SOLUTION STRUCTURE OF IBR-RING2 TANDEM DOMAIN FROM PARKIN
分子名称:E3 UBIQUITIN-PROTEIN LIGASE PARKIN, ZINC ION
著者Noh, Y.J., Mercier, P., Spratt, D.E., Shaw, G.S.
登録日2013-01-30
公開日2013-05-15
最終更新日2014-10-15
実験手法SOLUTION NMR
主引用文献A molecular explanation for the recessive nature of parkin-linked Parkinson's disease.
Nat Commun, 4, 2013