Author results

2REQ
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METHYLMALONYL-COA MUTASE, NON-PRODUCTIVE COA COMPLEX, IN OPEN CONFORMATION REPRESENTING SUBSTRATE-FREE STATE
Descriptor:METHYLMALONYL-COA MUTASE, COENZYME A, COBALAMIN
Authors:Evans, P.R., Mancia, F.
Deposit date:1997-09-22
Release date:1998-01-28
Last modified:2012-10-24
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Conformational changes on substrate binding to methylmalonyl CoA mutase and new insights into the free radical mechanism.
Structure, 6, 1998
3REQ
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METHYLMALONYL-COA MUTASE, SUBSTRATE-FREE STATE (POOR QUALITY STRUCTURE)
Descriptor:METHYLMALONYL-COA MUTASE, COBALAMIN, ADENOSINE
Authors:Evans, P.R., Mancia, F.
Deposit date:1997-12-04
Release date:1998-03-18
Last modified:2012-10-24
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Conformational changes on substrate binding to methylmalonyl CoA mutase and new insights into the free radical mechanism.
Structure, 6, 1998
4REQ
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METHYLMALONYL-COA MUTASE SUBSTRATE COMPLEX
Descriptor:METHYLMALONYL-COA MUTASE, COBALAMIN, SUCCINYL-COENZYME A, ...
Authors:Evans, P.R., Mancia, F.
Deposit date:1998-06-17
Release date:1999-01-13
Last modified:2012-10-24
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Conformational changes on substrate binding to methylmalonyl CoA mutase and new insights into the free radical mechanism.
Structure, 6, 1998
1REQ
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METHYLMALONYL-COA MUTASE
Descriptor:METHYLMALONYL-COA MUTASE, COBALAMIN, DESULFO-COENZYME A, ...
Authors:Evans, P.R., Mancia, F.
Deposit date:1996-01-19
Release date:1997-01-27
Last modified:2012-10-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:How coenzyme B12 radicals are generated: the crystal structure of methylmalonyl-coenzyme A mutase at 2 A resolution.
Structure, 4, 1996
6REQ
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METHYLMALONYL-COA MUTASE, 3-CARBOXYPROPYL-COA INHIBITOR COMPLEX
Descriptor:PROTEIN (METHYLMALONYL-COA MUTASE), 3-CARBOXYPROPYL-COENZYME A, COBALAMIN, ...
Authors:Evans, P.R., Mancia, F.
Deposit date:1998-09-03
Release date:1999-09-09
Last modified:2012-10-24
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of substrate complexes of methylmalonyl-CoA mutase.
Biochemistry, 38, 1999
7REQ
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METHYLMALONYL-COA MUTASE, 2-CARBOXYPROPYL-COA INHIBITOR COMPLEX
Descriptor:PROTEIN (METHYLMALONYL-COA MUTASE), 2-CARBOXYPROPYL-COENZYME A, COBALAMIN, ...
Authors:Evans, P.R., Mancia, F.
Deposit date:1998-09-10
Release date:1998-09-16
Last modified:2012-10-24
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of substrate complexes of methylmalonyl-CoA mutase.
Biochemistry, 38, 1999
3TRK
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STRUCTURE OF THE CHIKUNGUNYA VIRUS NSP2 PROTEASE
Descriptor:Nonstructural polyprotein, SODIUM ION
Authors:Cheung, J., Franklin, M., Mancia, F., Rudolph, M., Cassidy, M., Gary, E., Burshteyn, F., Love, J.
Deposit date:2011-09-09
Release date:2011-09-28
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.397 Å)
Cite:Structure of the Chikungunya virus nsP2 protease
To be Published
1HQP
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CRYSTAL STRUCTURE OF A TRUNCATED FORM OF PORCINE ODORANT-BINDING PROTEIN
Descriptor:ODORANT-BINDING PROTEIN, 2-ISOBUTYL-3-METHOXYPYRAZINE
Authors:Perduca, M., Mancia, F., Del Giorgio, R., Monaco, H.L.
Deposit date:2000-12-19
Release date:2001-01-17
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of a truncated form of porcine odorant-binding protein.
Proteins, 42, 2001
3TX3
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CYSZ, A PUTATIVE SULFATE PERMEASE
Descriptor:Uncharacterized protein involved in cysteine biosynthesis, SULFATE ION, CHLORIDE ION, ...
Authors:Assur, Z., Liu, Q., Hendrickson, W.A., Mancia, F., New York Consortium on Membrane Protein Structure (NYCOMPS)
Deposit date:2011-09-22
Release date:2011-11-09
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:CysZ, a putative sulfate permease
To be Published
4O6M
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STRUCTURE OF AF2299, A CDP-ALCOHOL PHOSPHOTRANSFERASE (CMP-BOUND)
Descriptor:AF2299, a CDP-alcohol phosphotransferase, CALCIUM ION, ...
Authors:Clarke, O.B., Sciara, G., Tomasek, D., Banerjee, S., Rajashankar, K.R., Shapiro, L., Mancia, F., New York Consortium on Membrane Protein Structure (NYCOMPS)
Deposit date:2013-12-22
Release date:2014-05-14
Last modified:2014-08-13
Method:X-RAY DIFFRACTION (1.901 Å)
Cite:Structural basis for catalysis in a CDP-alcohol phosphotransferase.
Nat Commun, 5, 2014
4O6N
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STRUCTURE OF AF2299, A CDP-ALCOHOL PHOSPHOTRANSFERASE (CDP-BOUND)
Descriptor:AF2299, a CDP-alcohol phosphotransferase, CALCIUM ION, ...
Authors:Clarke, O.B., Sciara, G., Tomasek, D., Banerjee, S., Rajashankar, K.R., Shapiro, L., Mancia, F., New York Consortium on Membrane Protein Structure (NYCOMPS)
Deposit date:2013-12-22
Release date:2014-05-14
Last modified:2014-08-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis for catalysis in a CDP-alcohol phosphotransferase.
Nat Commun, 5, 2014
4Q7C
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STRUCTURE OF AF2299, A CDP-ALCOHOL PHOSPHOTRANSFERASE
Descriptor:AF2299, a CDP-alcohol phosphotransferase, CALCIUM ION, ...
Authors:Clarke, O.B., Sciara, G., Tomasek, D., Banerjee, S., Rajashankar, K.R., Shapiro, L., Mancia, F., New York Consortium on Membrane Protein Structure (NYCOMPS)
Deposit date:2014-04-24
Release date:2014-05-28
Last modified:2014-08-13
Method:X-RAY DIFFRACTION (3.102 Å)
Cite:Structural basis for catalysis in a CDP-alcohol phosphotransferase.
Nat Commun, 5, 2014
5D91
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STRUCTURE OF A PHOSPHATIDYLINOSITOLPHOSPHATE (PIP) SYNTHASE FROM RENIBACTERIUM SALMONINARUM
Descriptor:AF2299 protein,Phosphatidylinositol synthase, SULFATE ION, Octadecane, ...
Authors:Clarke, O.B., Tomasek, D.T., Jorge, C.D., Belcher Dufrisne, M., Kim, M., Banerjee, S., Rajashankar, K.R., Hendrickson, W.A., Santos, H., Mancia, F.
Deposit date:2015-08-18
Release date:2015-11-11
Method:X-RAY DIFFRACTION (2.501 Å)
Cite:Structural basis for phosphatidylinositol-phosphate biosynthesis.
Nat Commun, 6, 2015
5D92
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STRUCTURE OF A PHOSPHATIDYLINOSITOLPHOSPHATE (PIP) SYNTHASE FROM RENIBACTERIUM SALMONINARUM
Descriptor:AF2299 protein,Phosphatidylinositol synthase, Octadecane, MAGNESIUM ION, ...
Authors:Clarke, O.B., Tomasek, D.T., Jorge, C.D., Belcher Dufrisne, M., Kim, M., Banerjee, S., Rajashankar, K.R., Hendrickson, W.A., Santos, H., Mancia, F.
Deposit date:2015-08-18
Release date:2015-11-04
Last modified:2015-11-11
Method:X-RAY DIFFRACTION (3.62 Å)
Cite:Structural basis for phosphatidylinositol-phosphate biosynthesis.
Nat Commun, 6, 2015
5EKE
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STRUCTURE OF THE POLYISOPRENYL-PHOSPHATE GLYCOSYLTRANSFERASE GTRB (F215A MUTANT)
Descriptor:Uncharacterized glycosyltransferase sll0501, URIDINE-5'-DIPHOSPHATE, MAGNESIUM ION
Authors:Ardiccioni, C., Clarke, O.B., Tomasek, D., Banerjee, S., Rajashankar, K.R., Liu, Q., Shapiro, L., Mancia, F., New York Consortium on Membrane Protein Structure (NYCOMPS)
Deposit date:2015-11-03
Release date:2016-01-06
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (3.001 Å)
Cite:Structure of the polyisoprenyl-phosphate glycosyltransferase GtrB and insights into the mechanism of catalysis.
Nat Commun, 7, 2016
5EKP
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STRUCTURE OF THE POLYISOPRENYL-PHOSPHATE GLYCOSYLTRANSFERASE GTRB (WT)
Descriptor:Uncharacterized glycosyltransferase sll0501, URIDINE-5'-DIPHOSPHATE, MAGNESIUM ION
Authors:Ardiccioni, C., Clarke, O.B., Tomasek, D., Banerjee, S., Rajashankar, K.R., Liu, Q., Shapiro, L., Mancia, F., New York Consortium on Membrane Protein Structure (NYCOMPS)
Deposit date:2015-11-03
Release date:2016-01-06
Last modified:2016-02-03
Method:X-RAY DIFFRACTION (3.194 Å)
Cite:Structure of the polyisoprenyl-phosphate glycosyltransferase GtrB and insights into the mechanism of catalysis.
Nat Commun, 7, 2016
5EZM
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CRYSTAL STRUCTURE OF ARNT FROM CUPRIAVIDUS METALLIDURANS IN THE APO STATE
Descriptor:4-amino-4-deoxy-L-arabinose transferase or related glycosyltransferases of PMT family, ZINC ION, MONO-TRANS, ...
Authors:Petrou, V.I., Clarke, O.B., Tomasek, D., Banerjee, S., Rajashankar, K.R., Mancia, F., New York Consortium on Membrane Protein Structure (NYCOMPS)
Deposit date:2015-11-26
Release date:2016-02-17
Last modified:2018-04-18
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structures of aminoarabinose transferase ArnT suggest a molecular basis for lipid A glycosylation.
Science, 351, 2016
5F15
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CRYSTAL STRUCTURE OF ARNT FROM CUPRIAVIDUS METALLIDURANS BOUND TO UNDECAPRENYL PHOSPHATE
Descriptor:4-amino-4-deoxy-L-arabinose (L-Ara4N) transferase, [(Z)-octadec-9-enyl] (2R)-2,3-bis(oxidanyl)propanoate, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ...
Authors:Petrou, V.I., Clarke, O.B., Tomasek, D., Banerjee, S., Rajashankar, K.R., Mancia, F., New York Consortium on Membrane Protein Structure (NYCOMPS)
Deposit date:2015-11-30
Release date:2016-02-17
Last modified:2018-04-18
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structures of aminoarabinose transferase ArnT suggest a molecular basis for lipid A glycosylation.
Science, 351, 2016
5K8Q
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CRYSTAL STRUCTURE OF CALCIUM-LOADED CALMODULIN IN COMPLEX WITH STRA6 CAMBP2-SITE PEPTIDE.
Descriptor:Calmodulin, Zgc:136689, CALCIUM ION, ...
Authors:Stowe, S.D., Clarke, O.B., Cavalier, M.C., Godoy-Ruiz, R., Mancia, F., Weber, D.J.
Deposit date:2016-05-30
Release date:2016-08-24
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (1.739 Å)
Cite:Structure of the STRA6 receptor for retinol uptake.
Science, 353, 2016
5SY1
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STRUCTURE OF THE STRA6 RECEPTOR FOR RETINOL UPTAKE IN COMPLEX WITH CALMODULIN
Descriptor:Calmodulin, STRA6, CALCIUM ION, ...
Authors:Clarke, O.B., Chen, Y., Mancia, F.
Deposit date:2016-08-10
Release date:2016-08-24
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structure of the STRA6 receptor for retinol uptake.
Science, 353, 2016
6D79
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STRUCTURE OF CYSZ, A SULFATE PERMEASE FROM PSEUDOMONAS FRAGI
Descriptor:Sulfate transporter CysZ
Authors:Sanghai, Z.A., Liu, Q., Clarke, O.B., Banerjee, S., Rajashankar, K.R., Hendrickson, W.A., Mancia, F.
Deposit date:2018-04-24
Release date:2018-05-16
Last modified:2018-06-06
Method:X-RAY DIFFRACTION (3.501 Å)
Cite:Structure-based analysis of CysZ-mediated cellular uptake of sulfate.
Elife, 7, 2018
6D9Z
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STRUCTURE OF CYSZ, A SULFATE PERMEASE FROM PSEUDOMONAS DENITRIFICANS
Descriptor:Sulfate transporter CysZ, B-OCTYLGLUCOSIDE
Authors:Sanghai, Z.A., Clarke, O.B., Liu, Q., Banerjee, S., Rajashankar, K.R., Hendrickson, W.A., Mancia, F.
Deposit date:2018-04-30
Release date:2018-05-23
Last modified:2018-06-06
Method:X-RAY DIFFRACTION (3.402132 Å)
Cite:Structure-based analysis of CysZ-mediated cellular uptake of sulfate.
Elife, 7, 2018
6GSR
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SINGLE PARTICLE CRYO-EM MAP OF HUMAN TRANSFERRIN RECEPTOR 1 - H-FERRITIN COMPLEX AT 5.5 ANGSTROM RESOLUTION.
Descriptor:Ferritin heavy chain, Transferrin receptor protein 1
Authors:Testi, C., Montemiglio, L.C., Vallone, B., Des Georges, A., Boffi, A., Mancia, F., Baiocco, P.
Deposit date:2018-06-15
Release date:2019-03-27
Last modified:2019-05-08
Method:ELECTRON MICROSCOPY (5.5 Å)
Cite:Cryo-EM structure of the human ferritin-transferrin receptor 1 complex.
Nat Commun, 10, 2019
6H5I
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SINGLE PARTICLE CRYO-EM MAP OF HUMAN TRANSFERRIN RECEPTOR 1 - H-FERRITIN COMPLEX.
Descriptor:Ferritin heavy chain, Transferrin receptor protein 1
Authors:Testi, C., Montemiglio, L.C., Vallone, B., Des Georges, A., Boffi, A., Mancia, F., Baiocco, P., Savino, C.
Deposit date:2018-07-24
Release date:2019-03-27
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Cryo-EM structure of the human ferritin-transferrin receptor 1 complex.
Nat Commun, 10, 2019
1NMT
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N-MYRISTOYL TRANSFERASE FROM CANDIDA ALBICANS AT 2.45 A
Descriptor:N-MYRISTOYL TRANSFERASE, GLYCEROL
Authors:Weston, S.A., Pauptit, R.A.
Deposit date:1997-12-11
Release date:1999-01-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Crystal structure of the anti-fungal target N-myristoyl transferase.
Nat.Struct.Biol., 5, 1998
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