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4BMN
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APO STRUCTURE OF SHORT-CHAIN ALCOHOL DEHYDROGENASE FROM RALSTONIA SP. DSM 6428
Descriptor:ALCLOHOL DEHYDROGENASE/SHORT-CHAIN DEHYDROGENASE, 1,2-ETHANEDIOL, TRIS(HYDROXYETHYL)AMINOMETHANE
Authors:Man, H., Kulig, J., Rother, D., Grogan, G.
Deposit date:2013-05-10
Release date:2014-03-19
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structures of Alcohol Dehydrogenases from Ralstonia and Sphingobium Spp. Reveal the Molecular Basis for Their Recognition of 'Bulky-Bulky' Ketones
Top.Catal., 57, 2014
4BMS
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SHORT CHAIN ALCOHOL DEHYDROGENASE FROM RALSTONIA SP. DSM 6428 IN COMPLEX WITH NADPH
Descriptor:ALCLOHOL DEHYDROGENASE/SHORT-CHAIN DEHYDROGENASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Man, H., Kulig, J., Rother, D., Grogan, G.
Deposit date:2013-05-10
Release date:2014-03-19
Method:X-RAY DIFFRACTION (2.89 Å)
Cite:Structures of Alcohol Dehydrogenases from Ralstonia and Sphingobium Spp. Reveal the Molecular Basis for Their Recognition of 'Bulky-Bulky' Ketones
Top.Catal., 57, 2014
4BMV
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SHORT-CHAIN DEHYDROGENASE FROM SPHINGOBIUM YANOIKUYAE IN COMPLEX WITH NADPH
Descriptor:SHORT-CHAIN DEHYDROGENASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Man, H., Kedziora, K., Lavandera-Garcia, I., Gotor-Fernandez, V., Grogan, G.
Deposit date:2013-05-10
Release date:2014-03-19
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structures of Alcohol Dehydrogenases from Ralstonia and Sphingobium Spp. Reveal the Molecular Basis for Their Recognition of 'Bulky-Bulky' Ketones
Top.Catal., 57, 2014
4C4O
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STRUCTURE OF CARBONYL REDUCTASE CPCR2 FROM CANDIDA PARAPSILOSIS IN COMPLEX WITH NADH
Descriptor:CARBONYL REDUCTASE CPCR2, ZINC ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
Authors:Man, H., Loderer, C., Ansorge-Schumacher, M., Grogan, G.
Deposit date:2013-09-06
Release date:2014-07-16
Last modified:2015-08-19
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structure of Nadh-Dependent Carbonyl Reductase (Cpcr2) from Candida Parapsilosis Provides Insight Into Mutations that Improve Catalytic Properties
Chemcatchem, 6, 2014
4CPD
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ALCOHOL DEHYDROGENASE TADH FROM THERMUS SP. ATN1
Descriptor:ALCOHOL DEHYDROGENASE, ZINC ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Man, H., Gargulio, S., Frank, A., Hollmann, F., Grogan, G.
Deposit date:2014-02-05
Release date:2014-12-17
Method:X-RAY DIFFRACTION (2.74 Å)
Cite:Structure of the Nadh-Dependent Thermostable Alcohol Dehydrogenase Tadh from Thermus Sp. Atn1 Provides a Platform for Engineering Specificity and Improved Compatibility with Inorganic Cofactor-Regeneration Catalysts
J.Mol.Catal., B Enzym., 105, 2014
4D3D
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STRUCTURE OF IMINE REDUCTASE BCSIRED FROM BACILLUS CEREUS BAG3X2
Descriptor:IMINE REDUCTASE, MAGNESIUM ION, O-ACETALDEHYDYL-HEXAETHYLENE GLYCOL
Authors:Man, H., Hart, S., Turkenburg, J.P., Grogan, G.
Deposit date:2014-10-21
Release date:2015-04-01
Last modified:2015-05-13
Method:X-RAY DIFFRACTION (1.71 Å)
Cite:Structure, Activity and Stereoselectivity of Nadph-Dependent Oxidoreductases Catalysing the S-Selective Reduction of the Imine Substrate 2-Methylpyrroline.
Chembiochem, 16, 2015
4D3F
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BCSIRED FROM BACILLUS CEREUS IN COMPLEX WITH NADPH
Descriptor:IMINE REDUCTASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Man, H., Hart, S., Turkenburg, J.P., Grogan, G.
Deposit date:2014-10-21
Release date:2015-04-01
Last modified:2015-05-13
Method:X-RAY DIFFRACTION (1.81 Å)
Cite:Structure, Activity and Stereoselectivity of Nadph-Dependent Oxidoreductases Catalysing the S-Selective Reduction of the Imine Substrate 2-Methylpyrroline.
Chembiochem, 16, 2015
4D3S
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IMINE REDUCTASE FROM NOCARDIOPSIS HALOPHILA
Descriptor:IMINE REDUCTASE, B-OCTYLGLUCOSIDE
Authors:Man, H., Hart, S., Turkenburg, J.P., Grogan, G.
Deposit date:2014-10-23
Release date:2015-04-01
Last modified:2015-05-13
Method:X-RAY DIFFRACTION (2.24 Å)
Cite:Structure, Activity and Stereoselectivity of Nadph-Dependent Oxidoreductases Catalysing the S-Selective Reduction of the Imine Substrate 2-Methylpyrroline.
Chembiochem, 16, 2015
5A9R
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APO FORM OF IMINE REDUCTASE FROM AMYCOLATOPSIS ORIENTALIS
Descriptor:IMINE REDUCTASE, ACETATE ION
Authors:Man, H., Aleku, G., Turner, N.J., Grogan, G.
Deposit date:2015-07-22
Release date:2016-06-01
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Stereoselectivity and Structural Characterization of an Imine Reductase (Ired) from Amycolatopsis Orientalis
Acs Catalysis, 6, 2016
5A9S
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NADPH COMPLEX OF IMINE REDUCTASE FROM AMYCOLATOPSIS ORIENTALIS
Descriptor:IMINE REDUCTASE, CALCIUM ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Man, H., Aleku, G., Turner, N.J., Grogan, G.
Deposit date:2015-07-22
Release date:2016-06-01
Last modified:2018-04-25
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Stereoselectivity and Structural Characterization of an Imine Reductase (IRED) from Amycolatopsis orientalis
Acs Catalysis, 6, 2016
5A9T
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IMINE REDUCTASE FROM AMYCOLATOPSIS ORIENTALIS IN COMPLEX WITH (R)- METHYLTETRAHYDROISOQUINOLINE
Descriptor:PUTATIVE DEHYDROGENASE, (1R)-1-methyl-1,2,3,4-tetrahydroisoquinoline, CALCIUM ION, ...
Authors:Man, H., Aleku, G., Turner, N.J., Grogan, G.
Deposit date:2015-07-22
Release date:2016-06-01
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Stereoselectivity and Structural Characterization of an Imine Reductase (Ired) from Amycolatopsis Orientalis
Acs Catalysis, 6, 2016
5FWN
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IMINE REDUCTASE FROM AMYCOLATOPSIS ORIENTALIS. CLOSED FORM IN IN COMPLEX WITH (R)- METHYLTETRAHYDROISOQUINOLINE
Descriptor:IMINE REDUCTASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, SULFATE ION, ...
Authors:Man, H., Aleku, G., Turner, N.J., Grogan, G.
Deposit date:2016-02-18
Release date:2016-06-01
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (2.14 Å)
Cite:Stereoselectivity and Structural Characterization of an Imine Reductase (Ired) from Amycolatopsis Orientalis
Acs Catalysis, 6, 2016
5G6R
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IMINE REDUCTASE FROM ASPERGILLUS ORYZAE
Descriptor:IMINE REDUCTASE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Man, H., Aleku, G., Turner, N.J., Grogan, G.
Deposit date:2016-06-23
Release date:2017-05-31
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:A reductive aminase from Aspergillus oryzae.
Nat Chem, 9, 2017
5G6S
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IMINE REDUCTASE FROM ASPERGILLUS ORYZAE IN COMPLEX WITH NADP(H) AND (R)-RASAGILINE
Descriptor:IMINE REDUCTASE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, RASAGILINE
Authors:Man, H., Aleku, G., Turner, N.J., Grogan, G.
Deposit date:2016-06-23
Release date:2017-05-31
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:A reductive aminase from Aspergillus oryzae.
Nat Chem, 9, 2017
4CY6
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APO STRUCTURE OF 2-HYDROXYBIPHENYL 3-MONOOXYGENASE HBPA
Descriptor:2-HYDROXYBIPHENYL-3-MONOOXYGENASE
Authors:Jensen, C.N., Farrugia, J.E., Frank, A., Man, H., Hart, S., Turkenburg, J.P., Grogan, G.
Deposit date:2014-04-10
Release date:2015-03-18
Last modified:2015-04-22
Method:X-RAY DIFFRACTION (2.76 Å)
Cite:Structures of the Apo and Fad-Bound Forms of 2-Hydroxybiphenyl 3-Monooxygenase (Hbpa) Locate Activity Hotspots Identified by Using Directed Evolution.
Chembiochem, 16, 2015
4CY8
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2-HYDROXYBIPHENYL 3-MONOOXYGENASE (HBPA) IN COMPLEX WITH FAD
Descriptor:2-HYDROXYBIPHENYL 3-MONOOXYGENASE, DIHYDROFLAVINE-ADENINE DINUCLEOTIDE
Authors:Jensen, C.N., Farrugia, J.E., Frank, A., Man, H., Hart, S., Turkenburg, J.P., Grogan, G.
Deposit date:2014-04-10
Release date:2015-03-18
Last modified:2015-04-22
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Structures of the Apo and Fad-Bound Forms of 2-Hydroxybiphenyl 3-Monooxygenase (Hbpa) Locate Activity Hotspots Identified by Using Directed Evolution.
Chembiochem, 16, 2015
5G1U
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LINALOOL DEHYDRATASE ISOMERASE IN COMPLEX WITH GERANIOL
Descriptor:LINALOOL DEHYDRATASE/ISOMERASE, Geraniol
Authors:Chambers, S., Hau, A., Man, H., Omar, M., Turkenburg, J.P., Grogan, G.
Deposit date:2016-03-30
Release date:2017-01-11
Last modified:2017-02-22
Method:X-RAY DIFFRACTION (2.57 Å)
Cite:Structural and functional insights into asymmetric enzymatic dehydration of alkenols.
Nat. Chem. Biol., 13, 2017
5G1V
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LINALOOL DEHYDRATASE ISOMERASE: SELENOMETHIONINE DERIVATIVE
Descriptor:LINALOOL DEHYDRATASE ISOMERASE
Authors:Chambers, S., Hau, A., Man, H., Omar, M., Turkenburg, J.P., Grogan, G.
Deposit date:2016-03-30
Release date:2017-01-11
Last modified:2017-02-22
Method:X-RAY DIFFRACTION (2.68 Å)
Cite:Structural and functional insights into asymmetric enzymatic dehydration of alkenols.
Nat. Chem. Biol., 13, 2017
5G1W
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APO STRUCTURE OF LINALOOL DEHYDRATASE-ISOMERASE
Descriptor:LINALOOL DEHYDRATASE/ISOMERASE, 1,2-ETHANEDIOL, METHYLMALONIC ACID
Authors:Chambers, S., Hau, A., Man, H., Omar, M., Turkenburg, J.P., Grogan, G.
Deposit date:2016-03-30
Release date:2017-01-11
Last modified:2017-02-22
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Structural and functional insights into asymmetric enzymatic dehydration of alkenols.
Nat. Chem. Biol., 13, 2017
6QD5
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X-RAY STRUCTURE OF THE HUMAN UREA CHANNEL SLC14A1/UT1
Descriptor:Urea transporter 1, B-OCTYLGLUCOSIDE, CHOLESTEROL HEMISUCCINATE, ...
Authors:Dietz, L., Chi, G., Pike, A.C.W., Moreau, C., Man, H., Snee, M., Scacioc, A., Shrestha, L., Mukhopadhyay, S.M.M., Mckinley, G., Ellis, K., Kliszcak, M., Chalk, R., Borkowska, O., Burgess-Brown, N.A., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Durr, K.L., Structural Genomics Consortium (SGC)
Deposit date:2018-12-31
Release date:2019-01-09
Method:X-RAY DIFFRACTION (2.398 Å)
Cite:X-ray Structure of the Human Urea Channel SLC14A1/UT1
To Be Published