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1MF4
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STRUCTURE-BASED DESIGN OF POTENT AND SELECTIVE INHIBITORS OF PHOSPHOLIPASE A2: CRYSTAL STRUCTURE OF THE COMPLEX FORMED BETWEEN PHOSHOLIPASE A2 FROM NAJA NAJA SAGITTIFERA AND A DESIGNED PEPTIDE INHIBITOR AT 1.9 A RESOLUTION
Descriptor:Phospholipase A2, VAL-ALA-PHE-ARG-SER, CALCIUM ION
Authors:Singh, R.K., Vikram, P., Paramsivam, M., Jabeen, T., Sharma, S., Makker, J., Dey, S., Kaur, P., Srinivasan, A., Singh, T.P.
Deposit date:2002-08-09
Release date:2003-09-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Design of specific peptide inhibitors for group I phospholipase A2: structure of a complex formed between phospholipase A2 from Naja naja sagittifera (group I) and a designed peptide inhibitor Val-Ala-Phe-Arg-Ser (VAFRS) at 1.9 A resolution reveals unique features
Biochemistry, 42, 2003
1SKG
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STRUCTURE-BASED RATIONAL DRUG DESIGN: CRYSTAL STRUCTURE OF THE COMPLEX FORMED BETWEEN PHOSPHOLIPASE A2 AND A PENTAPEPTIDE VAL-ALA-PHE-ARG-SER
Descriptor:Phospholipase A2, VAFRS, SULFATE ION, ...
Authors:Ethayathulla, A.S., Singh, N., Sharma, S., Makker, J., Dey, S., Perbandt, M., Betzel, C., Singh, T.P.
Deposit date:2004-03-04
Release date:2004-04-27
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.21 Å)
Cite:Structure-based rational drug design: Crystal structure of the complex formed between Phospholipase A2 and a pentapeptide Val-Ala-Phe-Arg-Ser
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1T37
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DESIGN OF SPECIFIC INHIBITORS OF PHOSPHOLIPASE A2: CRYSTAL STRUCTURE OF THE COMPLEX FORMED BETWEEN GROUP I PHOSPHOLIPASE A2 AND A DESIGNED PENTAPEPTIDE LEU-ALA-ILE-TYR-SER AT 2.6A RESOLUTION
Descriptor:Phospholipase A2 isoform 3, Synthetic peptide, ACETATE ION
Authors:Singh, R.K., Singh, N., Jabeen, T., Makker, J., Sharma, S., Dey, S., Singh, T.P.
Deposit date:2004-04-25
Release date:2004-05-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of the complex of group I PLA2 with a group II-specific peptide Leu-Ala-Ile-Tyr-Ser (LAIYS) at 2.6 A resolution.
J.Drug Target., 13, 2005