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5ND7
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BU of 5nd7 by Molmil
Microtubule-bound MKLP2 motor domain in the presence of AMPPNP
Descriptor: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-like protein KIF20A, ...
Authors:Atherton, J, Yu, I.-M, Cook, A, Muretta, J.M, Joseph, A.P, Major, J, Sourigues, Y, Clause, J, Topf, M, Rosenfeld, S.S, Houdusse, A, Moores, C.A.
Deposit date:2017-03-07
Release date:2017-10-04
Method:ELECTRON MICROSCOPY (7.9 Å)
Cite:The divergent mitotic kinesin MKLP2 exhibits atypical structure and mechanochemistry.
Elife, 6, 2017
5ND4
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BU of 5nd4 by Molmil
Microtubule-bound MKLP2 motor domain in the presence of ADP.AlFx
Descriptor: ADENOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Atherton, J, Yu, I.-M, Cook, A, Muretta, J.M, Joseph, A.P, Major, J, Sourigues, Y, Clause, J, Topf, M, Rosenfeld, S.S, Houdusse, A, Moores, C.A.
Deposit date:2017-03-07
Release date:2017-10-04
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:The divergent mitotic kinesin MKLP2 exhibits atypical structure and mechanochemistry.
Elife, 6, 2017
5ND2
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BU of 5nd2 by Molmil
Microtubule-bound MKLP2 motor domain in the presence of ADP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Atherton, J, Yu, I.M, Cook, A, Muretta, J.M, Joseph, A.P, Major, J, Sourigues, Y, Clause, J, Topf, M, Rosenfeld, S.S, Houdusse, A, Moores, C.A.
Deposit date:2017-03-07
Release date:2017-10-04
Method:ELECTRON MICROSCOPY (5.8 Å)
Cite:The divergent mitotic kinesin MKLP2 exhibits atypical structure and mechanochemistry.
Elife, 6, 2017
5ND3
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BU of 5nd3 by Molmil
Microtubule-bound MKLP2 motor domain in the with no nucleotide
Descriptor: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-like protein KIF20A, ...
Authors:Atherton, J, Yu, I.M, Cook, A, Muretta, J.M, Joseph, A.P, Major, J, Sourigues, Y, Clause, J, Topf, M, Rosenfeld, S.S, Houdusse, A, Moores, C.A.
Deposit date:2017-03-07
Release date:2017-10-04
Method:ELECTRON MICROSCOPY (6.1 Å)
Cite:The divergent mitotic kinesin MKLP2 exhibits atypical structure and mechanochemistry.
Elife, 6, 2017
4CK6
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BU of 4ck6 by Molmil
Pseudo-atomic model of microtubule-bound human kinesin-5 motor domain in the ADP.AlFx state, based on cryo-electron microscopy experiment.
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Goulet, A, Major, J, Jun, Y, Gross, S, Rosenfeld, S, Moores, C.
Deposit date:2013-12-30
Release date:2014-02-05
Last modified:2017-08-30
Method:ELECTRON MICROSCOPY (9.2 Å)
Cite:Comprehensive Structural Model of the Mechanochemical Cycle of a Mitotic Motor Highlights Molecular Adaptations in the Kinesin Family.
Proc.Natl.Acad.Sci.USA, 111, 2014
4CK7
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BU of 4ck7 by Molmil
Pseudo-atomic model of microtubule-bound human kinesin-5 motor domain in presence of adp.alfx (NECK-LINKER IN ITS DISCONNECTED CONFORMATION, based on cryo-electron microscopy experiment
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Goulet, A, Major, J, Jun, Y, Gross, S, Rosenfeld, S, Moores, C.
Deposit date:2013-12-30
Release date:2014-02-05
Last modified:2017-08-30
Method:ELECTRON MICROSCOPY (9.2 Å)
Cite:Comprehensive Structural Model of the Mechanochemical Cycle of a Mitotic Motor Highlights Molecular Adaptations in the Kinesin Family.
Proc.Natl.Acad.Sci.USA, 111, 2014
4CK5
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BU of 4ck5 by Molmil
Pseudo-atomic model of microtubule-bound human kinesin-5 motor domain in the ADP state, based on cryo-electron microscopy experiment.
Descriptor: ADENOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Goulet, A, Major, J, Jun, Y, Gross, S, Rosenfeld, S, Moores, C.
Deposit date:2013-12-30
Release date:2014-02-05
Last modified:2017-08-30
Method:ELECTRON MICROSCOPY (10 Å)
Cite:Comprehensive Structural Model of the Mechanochemical Cycle of a Mitotic Motor Highlights Molecular Adaptations in the Kinesin Family.
Proc.Natl.Acad.Sci.USA, 111, 2014
6VPP
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BU of 6vpp by Molmil
Cryo-EM structure of microtubule-bound KLP61F motor with tail domain in the nucleotide-free state
Descriptor: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-like protein Klp61F, ...
Authors:Bodrug, T, Wilson-Kubalek, E.M, Nithianantham, S, Debs, G, Sindelar, C.V, Milligan, R, Al-Bassam, J.
Deposit date:2020-02-04
Release date:2020-02-19
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:The kinesin-5 tail domain directly modulates the mechanochemical cycle of the motor domain for anti-parallel microtubule sliding.
Elife, 9, 2020
6VPO
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BU of 6vpo by Molmil
Cryo-EM structure of microtubule-bound KLP61F motor domain in the AMPPNP state
Descriptor: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-like protein Klp61F, ...
Authors:Bodrug, T, Wilson-Kubalek, E.M, Nithianantham, S, Debs, G, Sindelar, C.V, Milligan, R, Al-Bassam, J.
Deposit date:2020-02-04
Release date:2020-02-19
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:The kinesin-5 tail domain directly modulates the mechanochemical cycle of the motor domain for anti-parallel microtubule sliding.
Elife, 9, 2020
7S5U
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BU of 7s5u by Molmil
Extended bipolar assembly domain of kinesin-5 minifilament
Descriptor: Kinesin-like protein Klp61F
Authors:Nithianantham, S, Al-Bassam, J.
Deposit date:2021-09-12
Release date:2023-03-15
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (4.41 Å)
Cite:The kinesin-5 tail and bipolar miniflament domains are the origin of its microtubule crosslinking and sliding activity.
Mol.Biol.Cell, 2023
4AQV
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BU of 4aqv by Molmil
Model of human kinesin-5 motor domain (3HQD) and mammalian tubulin heterodimer (1JFF) docked into the 9.7-angstrom cryo-EM map of microtubule-bound kinesin-5 motor domain in the AMPPPNP state.
Descriptor: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, KINESIN-LIKE PROTEIN KIF11, ...
Authors:Goulet, A, Behnke-Parks, W.M, Sindelar, C.V, Rosenfeld, S.S, Moores, C.A.
Deposit date:2012-04-19
Release date:2012-11-21
Last modified:2017-08-23
Method:ELECTRON MICROSCOPY (9.7 Å)
Cite:The Structural Basis of Force Generation by the Mitotic Motor Kinesin-5.
J.Biol.Chem., 287, 2012
4AQW
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BU of 4aqw by Molmil
Model of human kinesin-5 motor domain (1II6, 3HQD) and mammalian tubulin heterodimer (1JFF) docked into the 9.5-angstrom cryo-EM map of microtubule-bound kinesin-5 motor domain in the rigor state.
Descriptor: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, KINESIN-LIKE PROTEIN KIF11, ...
Authors:Goulet, A, Behnke-Parks, W.M, Sindelar, C.V, Rosenfeld, S.S, Moores, C.A.
Deposit date:2012-04-19
Release date:2012-11-21
Last modified:2017-08-30
Method:ELECTRON MICROSCOPY (9.5 Å)
Cite:The Structural Basis of Force Generation by the Mitotic Motor Kinesin-5.
J.Biol.Chem., 287, 2012
4A5Y
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BU of 4a5y by Molmil
Intermediate state of human kinesin Eg5 in complex with Ispinesib
Descriptor: ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, ISPINESIB MESILATE, ...
Authors:Kaan, H.Y.K, Kozielski, F.
Deposit date:2011-10-29
Release date:2012-11-07
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:"Snapshots" of Ispinesib-Induced Conformational Changes in the Mitotic Kinesin Eg5.
J.Biol.Chem., 288, 2013

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