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6I9C
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BU of 6i9c by Molmil
Structure of the OTU domain of OTULIN G281R mutant
Descriptor: CHLORIDE ION, GLYCEROL, Ubiquitin thioesterase otulin
Authors:Damgaard, R.B, Elliott, P.R, Swatek, K.N, Maher, E.R, Stepensky, P, Elpeleg, O, Komander, D, Berkun, Y.
Deposit date:2018-11-22
Release date:2019-03-06
Last modified:2019-03-20
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:OTULIN deficiency in ORAS causes cell type-specific LUBAC degradation, dysregulated TNF signalling and cell death.
Embo Mol Med, 11, 2019

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