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2BG1
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BU of 2bg1 by Molmil
Active site restructuring regulates ligand recognition in classA Penicillin-binding proteins (PBPs)
Descriptor: CHLORIDE ION, PENICILLIN-BINDING PROTEIN 1B, SULFATE ION
Authors:Macheboeuf, P, Di Guilmi, A.M, Job, V, Vernet, T, Dideberg, O, Dessen, A.
Deposit date:2004-12-16
Release date:2005-03-11
Last modified:2019-10-16
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Active Site Restructuring Regulates Ligand Recognition in Class a Penicillin-Binding Proteins
Proc.Natl.Acad.Sci.USA, 102, 2005
2UWX
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BU of 2uwx by Molmil
Active site restructuring regulates ligand recognition in class A penicillin-binding proteins
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, PENICILLIN-BINDING PROTEIN 1B, ...
Authors:Macheboeuf, P, DiGuilmi, A.M, Job, V, Vernet, T, Dideberg, O, Dessen, A.
Deposit date:2007-03-23
Release date:2007-04-03
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.39 Å)
Cite:Active Site Restructuring Regulates Ligand Recognition in Class a Penicillin-Binding Proteins
Proc.Natl.Acad.Sci.USA, 102, 2005
2JCH
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BU of 2jch by Molmil
Structural and mechanistic basis of penicillin binding protein inhibition by lactivicins
Descriptor: (2E)-2-({(2S)-2-CARBOXY-2-[(PHENOXYACETYL)AMINO]ETHOXY}IMINO)PENTANEDIOIC ACID, 1,2-ETHANEDIOL, CHLORIDE ION, ...
Authors:Macheboeuf, P, Fisher, D.S, Brown, T.J, Zervosen, A, Luxen, A, Joris, B, Dessen, A, Schofield, C.J.
Deposit date:2006-12-23
Release date:2007-08-14
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural and Mechanistic Basis of Penicillin-Binding Protein Inhibition by Lactivicins
Nat.Chem.Biol., 3, 2007
2JE5
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BU of 2je5 by Molmil
STRUCTURAL AND MECHANISTIC BASIS OF PENICILLIN BINDING PROTEIN INHIBITION BY LACTIVICINS
Descriptor: (2E)-2-{[(2S)-2-(ACETYLAMINO)-2-CARBOXYETHOXY]IMINO}PENTANEDIOIC ACID, CHLORIDE ION, PENICILLIN-BINDING PROTEIN 1B, ...
Authors:Macheboeuf, P, Fisher, D.S, Brown, T.J, Zervosen, A, Luxen, A, Joris, B, Dessen, A, Schofield, C.J.
Deposit date:2007-01-15
Release date:2007-08-14
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural and Mechanistic Basis of Penicillin-Binding Protein Inhibition by Lactivicins
Nat.Chem.Biol., 3, 2007
2XD5
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BU of 2xd5 by Molmil
Structural insights into the catalytic mechanism and the role of Streptococcus pneumoniae PBP1b
Descriptor: CHLORIDE ION, N-BENZOYL-D-ALANINE, PENICILLIN-BINDING PROTEIN 1B, ...
Authors:Macheboeuf, P, Lemaire, D, Jamin, M, Dideberg, O, Dessen, A.
Deposit date:2010-04-29
Release date:2010-05-26
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Insights Into the Catalytic Mechanism and the Role of Streptococcus Pneumoniae Pbp1B
To be Published
2XNX
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BU of 2xnx by Molmil
BC1 fragment of streptococcal M1 protein in complex with human fibrinogen
Descriptor: FIBRINOGEN ALPHA CHAIN, FIBRINOGEN BETA CHAIN, FIBRINOGEN GAMMA CHAIN, ...
Authors:Macheboeuf, P, Y Fu, C, Zinkernagel, A.S, Johnson, J.E, Nizet, V, Ghosh, P.
Deposit date:2010-08-06
Release date:2011-04-13
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Streptococcal M1 Protein Constructs a Pathological Host Fibrinogen Network
Nature, 472, 2011
2XNY
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BU of 2xny by Molmil
A fragment of streptococcal M1 protein in complex with human fibrinogen
Descriptor: FIBRINOGEN ALPHA CHAIN, FIBRINOGEN BETA CHAIN, FIBRINOGEN GAMMA CHAIN, ...
Authors:Macheboeuf, P, Y Fu, C, Zinkernagel, A.S, Johnson, J.E, Nizet, V, Ghosh, P.
Deposit date:2010-08-06
Release date:2011-04-13
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (7.5 Å)
Cite:Streptococcal M1 Protein Constructs a Pathological Host Fibrinogen Network
Nature, 472, 2011
2XD1
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BU of 2xd1 by Molmil
ACTIVE SITE RESTRUCTURING REGULATES LIGAND RECOGNITION IN CLASS A PENICILLIN-BINDING PROTEINS
Descriptor: CEFOTAXIME, C3' cleaved, open, ...
Authors:Macheboeuf, P, Di Guilmi, A.M, Job, V, Vernet, T, Dideberg, O, Dessen, A.
Deposit date:2010-04-28
Release date:2010-05-26
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3 Å)
Cite:Active Site Restructuring Regulates Ligand Recognition in Class a Penicillin-Binding Proteins.
Proc.Natl.Acad.Sci.USA, 102, 2005
8CJH
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BU of 8cjh by Molmil
Architecture of a PKS-NRPS hybrid megaenzyme involved in the biosynthesis of the genotoxin colibactin
Descriptor: Colibactin hybrid non-ribosomal peptide synthetase/type I polyketide synthase ClbK
Authors:Bonhomme, S, Dessen, A, Macheboeuf, P.
Deposit date:2023-02-13
Release date:2023-04-26
Last modified:2023-06-14
Method:X-RAY DIFFRACTION (2.982 Å)
Cite:Architecture of a PKS-NRPS hybrid megaenzyme involved in the biosynthesis of the genotoxin colibactin.
Structure, 31, 2023
6EI6
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BU of 6ei6 by Molmil
CC2D1B coordinates ESRCT-III activity during the mitotic reformation of the nuclear envelope
Descriptor: Coiled-coil and C2 domain-containing protein 1-like, DI(HYDROXYETHYL)ETHER, SULFATE ION
Authors:Ventimiglia, L.N, Cuesta-Geijo, M.A, Martinelli, N, Caballe, A, Macheboeuf, P, Miguet, N, Parnham, I.M, Olmos, Y, Carlton, J.G, Weissehorn, W, martin-Serrano, J.
Deposit date:2017-09-18
Release date:2018-10-10
Last modified:2018-12-19
Method:X-RAY DIFFRACTION (2.461 Å)
Cite:CC2D1B Coordinates ESCRT-III Activity during the Mitotic Reformation of the Nuclear Envelope.
Dev. Cell, 47, 2018
7BK8
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BU of 7bk8 by Molmil
X-ray crystal structure of Pseudomonas aeruginosa MagC
Descriptor: MagC, PHOSPHATE ION
Authors:Zouhir, S, Contreras-Martel, C, Maragno Trindade, D, Attree, I, Dessen, A, Macheboeuf, P.
Deposit date:2021-01-15
Release date:2021-07-21
Last modified:2021-08-18
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:MagC is a NplC/P60-like member of the alpha-2-macroglobulin Mag complex of Pseudomonas aeruginosa that interacts with peptidoglycan.
Febs Lett., 595, 2021
4D81
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BU of 4d81 by Molmil
Metallosphera sedula Vps4 crystal structure
Descriptor: AAA ATPASE, CENTRAL DOMAIN PROTEIN, ADENOSINE-5'-DIPHOSPHATE
Authors:Caillat, C, Macheboeuf, P, Wu, Y, McCarthy, A.A, Boeri-Erba, E, Effantin, G, Gottlinger, H.G, Weissenhorn, W, Renesto, P.
Deposit date:2014-12-02
Release date:2015-11-25
Last modified:2015-12-16
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Asymmetric Ring Structure of Vps4 Required for Escrt-III Disassembly.
Nat.Commun., 6, 2015
4D80
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BU of 4d80 by Molmil
Metallosphera sedula Vps4 crystal structure
Descriptor: AAA ATPASE, CENTRAL DOMAIN PROTEIN
Authors:Caillat, C, Macheboeuf, P, Wu, Y, McCarthy, A.A, Boeri-Erba, E, Effantin, G, Gottlinger, H.G, Weissenhorn, W, Renesto, P.
Deposit date:2014-12-02
Release date:2015-10-28
Last modified:2015-12-16
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Asymmetric Ring Structure of Vps4 Required for Escrt-III Disassembly.
Nat.Commun., 6, 2015
4D82
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BU of 4d82 by Molmil
Metallosphera sedula Vps4 crystal structure
Descriptor: AAA ATPase, central domain protein, ADENOSINE-5'-DIPHOSPHATE
Authors:Caillat, C, Macheboeuf, P, Wu, Y, McCarthy, A.A, Boeri-Erba, E, Effantin, G, Gottlinger, H.G, Weissenhorn, W, Renesto, P.
Deposit date:2014-12-02
Release date:2015-11-25
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Asymmetric Ring Structure of Vps4 Required for Escrt-III Disassembly.
Nat.Commun., 6, 2015
4B50
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BU of 4b50 by Molmil
Crystal structure of the HIV-1 gp41 MPER-specific llama VHH 2H10
Descriptor: 2H10 LLAMA VHH
Authors:Lutje Hulsik, D, Sabin, C, Macheboeuf, P, Weissenhorn, W.
Deposit date:2012-08-02
Release date:2013-03-27
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:A Gp41 Mper-Specific Llama Vhh Requires a Hydrophobic Cdr3 for Neutralization But not for Antigen Recognition.
Plos Pathog., 9, 2013
2WSO
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BU of 2wso by Molmil
Structure of Cerulean Fluorescent Protein at physiological pH
Descriptor: GREEN FLUORESCENT PROTEIN
Authors:Lelimousin, M, Noirclerc-Savoye, M, Lazareno-Saez, C, Paetzold, B, Le Vot, S, Chazal, R, Macheboeuf, P, Field, M.J, Bourgeois, D, Royant, A.
Deposit date:2009-09-08
Release date:2009-09-29
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.15 Å)
Cite:Intrinsic Dynamics in Ecfp and Cerulean Control Fluorescence Quantum Yield.
Biochemistry, 48, 2009
2WSN
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BU of 2wsn by Molmil
Structure of Enhanced Cyan Fluorescent Protein at physiological pH
Descriptor: GREEN FLUORESCENT PROTEIN
Authors:Lelimousin, M, Noirclerc-Savoye, M, Lazareno-Saez, C, Paetzold, B, Le Vot, S, Chazal, R, Macheboeuf, P, Field, M.J, Bourgeois, D, Royant, A.
Deposit date:2009-09-08
Release date:2009-09-29
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.37 Å)
Cite:Intrinsic Dynamics in Ecfp and Cerulean Control Fluorescence Quantum Yield.
Biochemistry, 48, 2009
2OTO
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BU of 2oto by Molmil
N-terminal fragment of Streptococcus pyogenes M1 protein
Descriptor: M protein
Authors:McNamara, C.W, Ghosh, P.
Deposit date:2007-02-08
Release date:2008-03-18
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (3.04 Å)
Cite:Coiled-coil irregularities and instabilities in group A Streptococcus M1 are required for virulence.
Science, 319, 2008
6T39
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BU of 6t39 by Molmil
Crystal structure of rsEGFP2 in its off-state determined by SFX
Descriptor: Green fluorescent protein
Authors:Woodhouse, J, Coquelle, N, Adam, V, Barends, T.R.M, De La Mora, E, Bourgeois, D, Colletier, J.P, Schlichting, I, Weik, M.
Deposit date:2019-10-10
Release date:2020-02-19
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Photoswitching mechanism of a fluorescent protein revealed by time-resolved crystallography and transient absorption spectroscopy.
Nat Commun, 11, 2020
6T3A
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BU of 6t3a by Molmil
Difference-refined structure of rsEGFP2 10 ns following 400-nm laser irradiation of the off-state determined by SFX
Descriptor: Green fluorescent protein
Authors:Woodhouse, J, Coquelle, N, Adam, V, Barends, T.R.M, De La Mora, E, Bourgeois, D, Colletier, J.P, Schlichting, I, Weik, M.
Deposit date:2019-10-10
Release date:2020-02-19
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Photoswitching mechanism of a fluorescent protein revealed by time-resolved crystallography and transient absorption spectroscopy.
Nat Commun, 11, 2020
2XZE
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BU of 2xze by Molmil
Structural basis for AMSH-ESCRT-III CHMP3 interaction
Descriptor: CHARGED MULTIVESICULAR BODY PROTEIN 3, STAM-BINDING PROTEIN
Authors:Solomons, J, Sabin, C, Weissenhorn, W.
Deposit date:2010-11-25
Release date:2011-08-24
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural Basis for Escrt-III Chmp3 Recruitment of Amsh.
Structure, 19, 2011

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