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5HRJ
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BU of 5hrj by Molmil
Crystal structure of the scavenger receptor cysteine-rich domain 5 (SRCR5) from porcine CD163
Descriptor: Scavenger receptor cysteine-rich type 1 protein M130
Authors:Ma, H, Jiang, L, Qiao, S, Zhang, G, Li, R.
Deposit date:2016-01-23
Release date:2017-07-19
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of the scavenger receptor cysteine-rich domain 5 (SRCR5) from porcine CD163
To Be Published
5IRI
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BU of 5iri by Molmil
Structure of the mouse SAD-B AIS-KA1 fragment
Descriptor: Serine/threonine-protein kinase BRSK1
Authors:Ma, H, Wu, J.X, Wang, J, Wu, J.W.
Deposit date:2016-03-13
Release date:2016-06-15
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure and inhibition analysis of the mouse SAD-B C-terminal fragment
Biosci.Biotechnol.Biochem., 2016
5JFB
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BU of 5jfb by Molmil
Crystal structure of the scavenger receptor cysteine-rich domain 5 (SRCR5) from porcine CD163
Descriptor: Scavenger receptor cysteine-rich type 1 protein M130
Authors:Ma, H, Jiang, L, Qiao, S, Zhang, G, Li, R.
Deposit date:2016-04-19
Release date:2017-03-22
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:The Crystal Structure of the Fifth Scavenger Receptor Cysteine-Rich Domain of Porcine CD163 Reveals an Important Residue Involved in Porcine Reproductive and Respiratory Syndrome Virus Infection
J. Virol., 91, 2017
6K0L
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BU of 6k0l by Molmil
The crystal structure of simian CD163 SRCR5
Descriptor: Scavenger receptor cysteine-rich type 1 protein M130
Authors:Ma, H, Li, R, Jiang, L, Qiao, S, Zhang, G.
Deposit date:2019-05-07
Release date:2020-05-13
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:Structural comparison of CD163 SRCR5 from different species sheds some light on its involvement in porcine reproductive and respiratory syndrome virus-2 infection in vitro.
Vet Res, 52, 2021
6K0O
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BU of 6k0o by Molmil
The crystal structure of human CD163-like homolog SRCR8
Descriptor: Scavenger receptor cysteine-rich type 1 protein M160
Authors:Ma, H, Li, R, Jiang, L, Qiao, S, Zhang, G.
Deposit date:2019-05-07
Release date:2020-05-13
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Structural comparison of CD163 SRCR5 from different species sheds some light on its involvement in porcine reproductive and respiratory syndrome virus-2 infection in vitro.
Vet Res, 52, 2021
7X4I
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BU of 7x4i by Molmil
Crystal structure of nanobody aSA3 in complex with dimer SARS-CoV-1 RBD
Descriptor: Spike glycoprotein, nanobody aSA3
Authors:Ma, H, Zeng, W.H, Jin, T.C.
Deposit date:2022-03-02
Release date:2023-01-11
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.38 Å)
Cite:A bispecific nanobody dimer broadly neutralizes SARS-CoV-1 & 2 variants of concern and offers substantial protection against Omicron via low-dose intranasal administration.
Cell Discov, 8, 2022
7VOA
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BU of 7voa by Molmil
Crystal structure of SARS-CoV-2 RBD in complex with aRBD5
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, alpaca nanobody
Authors:Ma, H, Zeng, W.H, Jin, T.C.
Deposit date:2021-10-13
Release date:2022-08-10
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Hetero-bivalent nanobodies provide broad-spectrum protection against SARS-CoV-2 variants of concern including Omicron.
Cell Res., 32, 2022
7C2E
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BU of 7c2e by Molmil
GLP-1R-Gs complex structure with a small molecule full agonist
Descriptor: 2-[[4-[6-[(4-cyano-2-fluoranyl-phenyl)methoxy]pyridin-2-yl]-3,6-dihydro-2~{H}-pyridin-1-yl]methyl]-3-[[(2~{S})-oxetan-2-yl]methyl]imidazo[4,5-b]pyridine-5-carboxylic acid, Glucagon-like peptide 1 receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Ma, H, Yuan, D.P, Huang, W, Wenge, Z, Xu, E.
Deposit date:2020-05-07
Release date:2020-08-26
Last modified:2020-12-16
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Structural insights into the activation of GLP-1R by a small molecule agonist.
Cell Res., 30, 2020
4UEI
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BU of 4uei by Molmil
Solution structure of the sterol carrier protein domain 2 of Helicoverpa armigera
Descriptor: STEROL CARRIER PROTEIN 2/3-OXOACYL-COA THIOLASE
Authors:Liu, X, Ma, H, Yan, X, Hong, H, Peng, J, Peng, R.
Deposit date:2014-12-18
Release date:2015-12-30
Last modified:2019-10-23
Method:SOLUTION NMR
Cite:NMR Structure and Function of Helicoverpa Armigera Sterol Carrier Protein-2, an Important Insecticidal Target from the Cotton Bollworm.
Sci.Rep., 5, 2015
5JA5
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BU of 5ja5 by Molmil
Crystal structure of the rice Topless related protein 2 (TPR2) N-terminal topless domain (1-209) L111A and L130A mutant in complex with rice D53 repressor EAR peptide motif
Descriptor: Protein TPR1, The rice D53 peptide (a.a. 794-808), ZINC ION
Authors:Ke, J, Ma, H, Gu, X, Brunzelle, J.S, Xu, H.E, Melcher, K.
Deposit date:2016-04-12
Release date:2017-07-05
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:A D53 repression motif induces oligomerization of TOPLESS corepressors and promotes assembly of a corepressor-nucleosome complex.
Sci Adv, 3, 2017
5JHP
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BU of 5jhp by Molmil
Crystal structure of the rice Topless related protein 2 (TPR2) N-terminal topless domain (1-209) L179A and I195A mutant in complex with rice D53 repressor EAR peptide motif
Descriptor: Protein TPR1, The rice D53 EAR peptide (794-808)
Authors:Ke, J, Ma, H, Gu, X, Brunzelle, J.S, Xu, H.E, Melcher, K.
Deposit date:2016-04-21
Release date:2017-07-05
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:A D53 repression motif induces oligomerization of TOPLESS corepressors and promotes assembly of a corepressor-nucleosome complex.
Sci Adv, 3, 2017
5J9K
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BU of 5j9k by Molmil
Crystal structure of the rice Topless related protein 2 (TPR2) N-terminal topless domain (1-209) in complex with rice D53 repressor EAR peptide motif
Descriptor: Protein TPR1, ZINC ION, rice D53 peptide 794-808
Authors:Ke, J, Ma, H, Gu, X, Brunzelle, J.S, Xu, H.E, Melcher, K.
Deposit date:2016-04-10
Release date:2017-07-05
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:A D53 repression motif induces oligomerization of TOPLESS corepressors and promotes assembly of a corepressor-nucleosome complex.
Sci Adv, 3, 2017
5JGC
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BU of 5jgc by Molmil
Crystal structure of the rice Topless related protein 2 (TPR2) N-terminal topless domain (1-209) L111A, L130A, L179A and I195A mutant
Descriptor: Protein TPR1, ZINC ION
Authors:Ke, J, Ma, H, Gu, X, Brunzelle, J.S, Xu, H.E, Melcher, K.
Deposit date:2016-04-20
Release date:2017-07-05
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.08 Å)
Cite:A D53 repression motif induces oligomerization of TOPLESS corepressors and promotes assembly of a corepressor-nucleosome complex.
Sci Adv, 3, 2017
1AFS
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BU of 1afs by Molmil
RECOMBINANT RAT LIVER 3-ALPHA-HYDROXYSTEROID DEHYDROGENASE (3-ALPHA-HSD) COMPLEXED WITH NADP AND TESTOSTERONE
Descriptor: 3-ALPHA-HYDROXYSTEROID DEHYDROGENASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, TESTOSTERONE
Authors:Bennett, M.J, Albert, R.H, Jez, J.M, Ma, H, Penning, T.M, Lewis, M.
Deposit date:1997-03-13
Release date:1997-10-08
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Steroid recognition and regulation of hormone action: crystal structure of testosterone and NADP+ bound to 3 alpha-hydroxysteroid/dihydrodiol dehydrogenase.
Structure, 5, 1997
4ZHE
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BU of 4zhe by Molmil
Crystal structure of the SeMet substituted Topless related protein 2 (TPR2) N-terminal domain (1-209) from rice
Descriptor: ASPR2 protein
Authors:Ke, J, Ma, H, Gu, X, Brunzelle, J.S, Xu, H.E, Melcher, K.
Deposit date:2015-04-24
Release date:2015-08-05
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis for recognition of diverse transcriptional repressors by the TOPLESS family of corepressors.
Sci Adv, 1, 2015
5C6V
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BU of 5c6v by Molmil
Crystal structure of the rice Topless related protein 2 (TPR2) N-terminal domain (1-209) in complex with Arabidopsis NINJA peptide
Descriptor: AFP homolog 2, ASPR2 protein
Authors:Ke, J, Ma, H, Gu, X, Brunzelle, J.S, Xu, H.E, Melcher, K.
Deposit date:2015-06-23
Release date:2015-08-05
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural basis for recognition of diverse transcriptional repressors by the TOPLESS family of corepressors.
Sci Adv, 1, 2015
5C7F
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BU of 5c7f by Molmil
Crystal structure of the rice Topless related protein 2 (TPR2) N-terminal domain (1-209) in complex with Arabidopsis IAA1 peptide
Descriptor: ASPR2 protein, Auxin-responsive protein IAA1, ZINC ION
Authors:Ke, J, Ma, H, Gu, X, Brunzelle, J.S, Xu, H.E, Melcher, K.
Deposit date:2015-06-24
Release date:2015-08-05
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural basis for recognition of diverse transcriptional repressors by the TOPLESS family of corepressors.
Sci Adv, 1, 2015
5C6Q
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BU of 5c6q by Molmil
Crystal structure of the apo TOPLESS related protein 2 (TPR2) N-terminal domain (1-209) from rice
Descriptor: ASPR2 protein, ZINC ION
Authors:Ke, J, Ma, H, Gu, X, Brunzelle, J.S, Xu, H.E, Melcher, K.
Deposit date:2015-06-23
Release date:2015-08-05
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.251 Å)
Cite:Structural basis for recognition of diverse transcriptional repressors by the TOPLESS family of corepressors.
Sci Adv, 1, 2015
5C7E
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BU of 5c7e by Molmil
Crystal structure of the rice Topless related protein 2 (TPR2) N-terminal domain (1-209) in complex with Arabidopsis IAA10 peptide
Descriptor: ASPR2 protein, Auxin-responsive protein IAA10, ZINC ION
Authors:Ke, J, Ma, H, Gu, X, Brunzelle, J.S, Xu, H.E, Melcher, K.
Deposit date:2015-06-24
Release date:2015-08-05
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural basis for recognition of diverse transcriptional repressors by the TOPLESS family of corepressors.
Sci Adv, 1, 2015
7XA3
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BU of 7xa3 by Molmil
Cryo-EM structure of the CCL2 bound CCR2-Gi complex
Descriptor: C-C motif chemokine 2, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
Authors:Shao, Z, Tan, Y, Shen, Q, Yao, B, Hou, L, Qin, J, Xu, P, Mao, C, Chen, L, Zhang, H, Shen, D, Zhang, C, Li, W, Du, X, Li, F, Chen, Z, Jiang, Y, Xu, H.E, Ying, S, Ma, H, Zhang, Y, Shen, H.
Deposit date:2022-03-17
Release date:2022-08-24
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Molecular insights into ligand recognition and activation of chemokine receptors CCR2 and CCR3.
Cell Discov, 8, 2022
7X9Y
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BU of 7x9y by Molmil
Cryo-EM structure of the apo CCR3-Gi complex
Descriptor: C-C chemokine receptor type 3, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
Authors:Shao, Z, Tan, Y, Shen, Q, Yao, B, Hou, L, Qin, J, Xu, P, Mao, C, Chen, L, Zhang, H, Shen, D, Zhang, C, Li, W, Du, X, Li, F, Chen, Z, Jiang, Y, Xu, H.E, Ying, S, Ma, H, Zhang, Y, Shen, H.
Deposit date:2022-03-16
Release date:2022-08-24
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Molecular insights into ligand recognition and activation of chemokine receptors CCR2 and CCR3.
Cell Discov, 8, 2022
7DUQ
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BU of 7duq by Molmil
Cryo-EM structure of the compound 2 and GLP-1-bound human GLP-1 receptor-Gs complex
Descriptor: CHOLESTEROL, Glucagon-like peptide 1, Glucagon-like peptide 1 receptor, ...
Authors:Cong, Z, Chen, L, Ma, H, Zhou, Q, Zou, X, Ye, C, Dai, A, Liu, Q, Huang, W, Sun, X, Wang, X, Xu, P, Zhao, L, Xia, T, Zhong, W, Yang, D, Xu, H.E, Zhang, Y, Wang, M.
Deposit date:2021-01-11
Release date:2021-07-14
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:Molecular insights into ago-allosteric modulation of the human glucagon-like peptide-1 receptor.
Nat Commun, 12, 2021
7DUR
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BU of 7dur by Molmil
Cryo-EM structure of the compound 2-bound human GLP-1 receptor-Gs complex
Descriptor: CHOLESTEROL, Glucagon-like peptide 1 receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Cong, Z, Chen, L, Ma, H, Zhou, Q, Zou, X, Ye, C, Dai, A, Liu, Q, Huang, W, Sun, X, Wang, X, Xu, P, Zhao, L, Xia, T, Zhong, W, Yang, D, Xu, H.E, Zhang, Y, Wang, M.
Deposit date:2021-01-11
Release date:2021-08-11
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Molecular insights into ago-allosteric modulation of the human glucagon-like peptide-1 receptor.
Nat Commun, 12, 2021
7W28
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BU of 7w28 by Molmil
Crystal Structure of SETD3-SAH in complex with betaA-4PyrAla73 peptide
Descriptor: Actin, cytoplasmic 1, Histone-lysine N-methyltransferase setd3, ...
Authors:Li, H, Ma, H.
Deposit date:2021-11-22
Release date:2022-10-05
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Histidine methyltransferase SETD3 methylates structurally diverse histidine mimics in actin.
Protein Sci., 31, 2022
7W29
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BU of 7w29 by Molmil
Crystal Structure of SETD3-SAH in complex with betaA-Orn73 peptide
Descriptor: Actin, cytoplasmic 1, N-terminally processed, ...
Authors:Li, H, Ma, H.
Deposit date:2021-11-23
Release date:2022-10-05
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Histidine methyltransferase SETD3 methylates structurally diverse histidine mimics in actin.
Protein Sci., 31, 2022

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