Author results

5HRJ
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CRYSTAL STRUCTURE OF THE SCAVENGER RECEPTOR CYSTEINE-RICH DOMAIN 5 (SRCR5) FROM PORCINE CD163
Descriptor:Scavenger receptor cysteine-rich type 1 protein M130
Authors:Ma, H., Jiang, L., Qiao, S., Zhang, G., Li, R.
Deposit date:2016-01-23
Release date:2017-07-19
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of the scavenger receptor cysteine-rich domain 5 (SRCR5) from porcine CD163
To Be Published
5IRI
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STRUCTURE OF THE MOUSE SAD-B AIS-KA1 FRAGMENT
Descriptor:Serine/threonine-protein kinase BRSK1
Authors:Ma, H., Wu, J.X., Wang, J., Wu, J.W.
Deposit date:2016-03-13
Release date:2016-06-15
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure and inhibition analysis of the mouse SAD-B C-terminal fragment
Biosci.Biotechnol.Biochem., 2016
5JFB
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CRYSTAL STRUCTURE OF THE SCAVENGER RECEPTOR CYSTEINE-RICH DOMAIN 5 (SRCR5) FROM PORCINE CD163
Descriptor:Scavenger receptor cysteine-rich type 1 protein M130
Authors:Ma, H., Jiang, L., Qiao, S., Zhang, G., Li, R.
Deposit date:2016-04-19
Release date:2017-03-22
Method:X-RAY DIFFRACTION (2 Å)
Cite:The Crystal Structure of the Fifth Scavenger Receptor Cysteine-Rich Domain of Porcine CD163 Reveals an Important Residue Involved in Porcine Reproductive and Respiratory Syndrome Virus Infection
J. Virol., 91, 2017
4UEI
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SOLUTION STRUCTURE OF THE STEROL CARRIER PROTEIN DOMAIN 2 OF HELICOVERPA ARMIGERA
Descriptor:STEROL CARRIER PROTEIN 2/3-OXOACYL-COA THIOLASE
Authors:Liu, X., Ma, H., Yan, X., Hong, H., Peng, J., Peng, R.
Deposit date:2014-12-18
Release date:2015-12-30
Method:SOLUTION NMR
Cite:NMR Structure and Function of Helicoverpa Armigera Sterol Carrier Protein-2, an Important Insecticidal Target from the Cotton Bollworm.
Sci.Rep., 5, 2015
5J9K
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CRYSTAL STRUCTURE OF THE RICE TOPLESS RELATED PROTEIN 2 (TPR2) N-TERMINAL TOPLESS DOMAIN (1-209) IN COMPLEX WITH RICE D53 REPRESSOR EAR PEPTIDE MOTIF
Descriptor:Protein TPR1, rice D53 peptide 794-808, ZINC ION
Authors:Ke, J., Ma, H., Gu, X., Brunzelle, J.S., Xu, H.E., Melcher, K.
Deposit date:2016-04-10
Release date:2017-07-05
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:A D53 repression motif induces oligomerization of TOPLESS corepressors and promotes assembly of a corepressor-nucleosome complex.
Sci Adv, 3, 2017
5JA5
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CRYSTAL STRUCTURE OF THE RICE TOPLESS RELATED PROTEIN 2 (TPR2) N-TERMINAL TOPLESS DOMAIN (1-209) L111A AND L130A MUTANT IN COMPLEX WITH RICE D53 REPRESSOR EAR PEPTIDE MOTIF
Descriptor:Protein TPR1, The rice D53 peptide (a.a. 794-808), ZINC ION
Authors:Ke, J., Ma, H., Gu, X., Brunzelle, J.S., Xu, H.E., Melcher, K.
Deposit date:2016-04-12
Release date:2017-07-05
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:A D53 repression motif induces oligomerization of TOPLESS corepressors and promotes assembly of a corepressor-nucleosome complex.
Sci Adv, 3, 2017
5JGC
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CRYSTAL STRUCTURE OF THE RICE TOPLESS RELATED PROTEIN 2 (TPR2) N-TERMINAL TOPLESS DOMAIN (1-209) L111A, L130A, L179A AND I195A MUTANT
Descriptor:Protein TPR1, ZINC ION
Authors:Ke, J., Ma, H., Gu, X., Brunzelle, J.S., Xu, H.E., Melcher, K.
Deposit date:2016-04-20
Release date:2017-07-05
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2.08 Å)
Cite:A D53 repression motif induces oligomerization of TOPLESS corepressors and promotes assembly of a corepressor-nucleosome complex.
Sci Adv, 3, 2017
5JHP
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CRYSTAL STRUCTURE OF THE RICE TOPLESS RELATED PROTEIN 2 (TPR2) N-TERMINAL TOPLESS DOMAIN (1-209) L179A AND I195A MUTANT IN COMPLEX WITH RICE D53 REPRESSOR EAR PEPTIDE MOTIF
Descriptor:Protein TPR1, The rice D53 EAR peptide (794-808)
Authors:Ke, J., Ma, H., Gu, X., Brunzelle, J.S., Xu, H.E., Melcher, K.
Deposit date:2016-04-21
Release date:2017-07-05
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:A D53 repression motif induces oligomerization of TOPLESS corepressors and promotes assembly of a corepressor-nucleosome complex.
Sci Adv, 3, 2017
1AFS
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RECOMBINANT RAT LIVER 3-ALPHA-HYDROXYSTEROID DEHYDROGENASE (3-ALPHA-HSD) COMPLEXED WITH NADP AND TESTOSTERONE
Descriptor:3-ALPHA-HYDROXYSTEROID DEHYDROGENASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, TESTOSTERONE
Authors:Bennett, M.J., Albert, R.H., Jez, J.M., Ma, H., Penning, T.M., Lewis, M.
Deposit date:1997-03-13
Release date:1997-10-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Steroid recognition and regulation of hormone action: crystal structure of testosterone and NADP+ bound to 3 alpha-hydroxysteroid/dihydrodiol dehydrogenase.
Structure, 5, 1997
4ZHE
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CRYSTAL STRUCTURE OF THE SEMET SUBSTITUTED TOPLESS RELATED PROTEIN 2 (TPR2) N-TERMINAL DOMAIN (1-209) FROM RICE
Descriptor:ASPR2 protein
Authors:Ke, J., Ma, H., Gu, X., Brunzelle, J.S., Xu, H.E., Melcher, K.
Deposit date:2015-04-24
Release date:2015-08-05
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis for recognition of diverse transcriptional repressors by the TOPLESS family of corepressors.
Sci Adv, 1, 2015
5C6Q
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CRYSTAL STRUCTURE OF THE APO TOPLESS RELATED PROTEIN 2 (TPR2) N-TERMINAL DOMAIN (1-209) FROM RICE
Descriptor:ASPR2 protein, ZINC ION
Authors:Ke, J., Ma, H., Gu, X., Brunzelle, J.S., Xu, H.E., Melcher, K.
Deposit date:2015-06-23
Release date:2015-08-05
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (3.251 Å)
Cite:Structural basis for recognition of diverse transcriptional repressors by the TOPLESS family of corepressors.
Sci Adv, 1, 2015
5C6V
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CRYSTAL STRUCTURE OF THE RICE TOPLESS RELATED PROTEIN 2 (TPR2) N-TERMINAL DOMAIN (1-209) IN COMPLEX WITH ARABIDOPSIS NINJA PEPTIDE
Descriptor:ASPR2 protein, AFP homolog 2
Authors:Ke, J., Ma, H., Gu, X., Brunzelle, J.S., Xu, H.E., Melcher, K.
Deposit date:2015-06-23
Release date:2015-08-05
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural basis for recognition of diverse transcriptional repressors by the TOPLESS family of corepressors.
Sci Adv, 1, 2015
5C7E
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CRYSTAL STRUCTURE OF THE RICE TOPLESS RELATED PROTEIN 2 (TPR2) N-TERMINAL DOMAIN (1-209) IN COMPLEX WITH ARABIDOPSIS IAA10 PEPTIDE
Descriptor:ASPR2 protein, Auxin-responsive protein IAA10, ZINC ION
Authors:Ke, J., Ma, H., Gu, X., Brunzelle, J.S., Xu, H.E., Melcher, K.
Deposit date:2015-06-24
Release date:2015-08-05
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural basis for recognition of diverse transcriptional repressors by the TOPLESS family of corepressors.
Sci Adv, 1, 2015
5C7F
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CRYSTAL STRUCTURE OF THE RICE TOPLESS RELATED PROTEIN 2 (TPR2) N-TERMINAL DOMAIN (1-209) IN COMPLEX WITH ARABIDOPSIS IAA1 PEPTIDE
Descriptor:ASPR2 protein, Auxin-responsive protein IAA1, ZINC ION
Authors:Ke, J., Ma, H., Gu, X., Brunzelle, J.S., Xu, H.E., Melcher, K.
Deposit date:2015-06-24
Release date:2015-08-05
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural basis for recognition of diverse transcriptional repressors by the TOPLESS family of corepressors.
Sci Adv, 1, 2015
5KU9
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CRYSTAL STRUCTURE OF MCL1 WITH COMPOUND 1
Descriptor:Induced myeloid leukemia cell differentiation protein Mcl-1, SODIUM ION, (3~{S})-3-azanyl-4-(4-bromophenyl)-~{N}-[(3~{S})-1-[2-[[(2~{R})-1-(3,4-dichlorophenyl)-4-(methylamino)-4-oxidanylidene-butan-2-yl]amino]-2-oxidanylidene-ethyl]-2-oxidanylidene-4,5-dihydro-3~{H}-1-benzazepin-3-yl]butanamide
Authors:Ferguson, A.D.
Deposit date:2016-07-13
Release date:2017-01-11
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure Based Design of Non-Natural Peptidic Macrocyclic Mcl-1 Inhibitors.
ACS Med Chem Lett, 8, 2017
5MES
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MCL1 FAB COMPLEX IN COMPLEX WITH COMPOUND 29
Descriptor:Induced myeloid leukemia cell differentiation protein Mcl-1 homolog,Induced myeloid leukemia cell differentiation protein Mcl-1, Heavy Chain, Light Chain, ...
Authors:Hargreaves, D.
Deposit date:2016-11-16
Release date:2017-01-18
Last modified:2017-03-08
Method:X-RAY DIFFRACTION (2.24 Å)
Cite:Structure Based Design of Non-Natural Peptidic Macrocyclic Mcl-1 Inhibitors.
ACS Med Chem Lett, 8, 2017
5MEV
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MCL1 FAB COMPLEX IN COMPLEX WITH COMPOUND 21
Descriptor:Induced myeloid leukemia cell differentiation protein Mcl-1 homolog,Induced myeloid leukemia cell differentiation protein Mcl-1, Fab Heavy Chain, Fab Light Chain, ...
Authors:Hargreaves, D.
Deposit date:2016-11-16
Release date:2017-01-18
Last modified:2017-03-08
Method:X-RAY DIFFRACTION (2.94 Å)
Cite:Structure Based Design of Non-Natural Peptidic Macrocyclic Mcl-1 Inhibitors
Acs Med.Chem.Lett., 8, 2017
3SOU
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STRUCTURE OF UHRF1 PHD FINGER IN COMPLEX WITH HISTONE H3 1-9 PEPTIDE
Descriptor:E3 ubiquitin-protein ligase UHRF1, Histone H3, ZINC ION
Authors:Rajakumara, E., Patel, D.J.
Deposit date:2011-06-30
Release date:2011-08-03
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.8001 Å)
Cite:PHD Finger Recognition of Unmodified Histone H3R2 Links UHRF1 to Regulation of Euchromatic Gene Expression.
Mol.Cell, 43, 2011
3SOW
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STRUCTURE OF UHRF1 PHD FINGER IN COMPLEX WITH HISTONE H3K4ME3 1-9 PEPTIDE
Descriptor:E3 ubiquitin-protein ligase UHRF1, Histone H3, ZINC ION
Authors:Rajakumara, E., Patel, D.J.
Deposit date:2011-06-30
Release date:2011-08-03
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.9501 Å)
Cite:PHD Finger Recognition of Unmodified Histone H3R2 Links UHRF1 to Regulation of Euchromatic Gene Expression.
Mol.Cell, 43, 2011
3SOX
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STRUCTURE OF UHRF1 PHD FINGER IN THE FREE FORM
Descriptor:E3 ubiquitin-protein ligase UHRF1, ZINC ION
Authors:Rajakumara, E., Patel, D.J.
Deposit date:2011-06-30
Release date:2011-08-03
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.6501 Å)
Cite:PHD Finger Recognition of Unmodified Histone H3R2 Links UHRF1 to Regulation of Euchromatic Gene Expression.
Mol.Cell, 43, 2011
6A50
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STRUCTURE OF BENZOYLFORMATE DECARBOXYLASES IN COMPLEX WITH COFACTOR TPP
Descriptor:benzoylformate decarboxylases, MAGNESIUM ION, THIAMINE DIPHOSPHATE
Authors:Guo, Y., Wang, S., Nie, Y., Li, S.
Deposit date:2018-06-21
Release date:2019-02-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:A Synthetic Pathway for Acetyl-Coenzyme A Biosynthesis
Nat Commun, 2019
5KCM
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CRYSTAL STRUCTURE OF IRON-SULFUR CLUSTER CONTAINING PHOTOLYASE PHRB MUTANT I51W
Descriptor:(6-4) photolyase, FLAVIN-ADENINE DINUCLEOTIDE, IRON/SULFUR CLUSTER, ...
Authors:Yang, X., Bowatte, K., Zhang, F., Lamparter, T.
Deposit date:2016-06-06
Release date:2017-01-11
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (2.149 Å)
Cite:Crystal Structures of Bacterial (6-4) Photolyase Mutants with Impaired DNA Repair Activity.
Photochem. Photobiol., 93, 2017
5LFA
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CRYSTAL STRUCTURE OF IRON-SULFUR CLUSTER CONTAINING BACTERIAL (6-4) PHOTOLYASE PHRB - Y424F MUTANT WITH IMPAIRED DNA REPAIR ACTIVITY
Descriptor:(6-4) photolyase, FLAVIN-ADENINE DINUCLEOTIDE, 1-deoxy-1-(6,7-dimethyl-2,4-dioxo-3,4-dihydropteridin-8(2H)-yl)-D-ribitol, ...
Authors:Kwiatkowski, D., Zhang, F., Krauss, N., Lamparter, T., Scheerer, P.
Deposit date:2016-06-30
Release date:2017-01-11
Last modified:2017-03-01
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal Structures of Bacterial (6-4) Photolyase Mutants with Impaired DNA Repair Activity.
Photochem. Photobiol., 93, 2017
3PE6
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CRYSTAL STRUCTURE OF A SOLUBLE FORM OF HUMAN MGLL IN COMPLEX WITH AN INHIBITOR
Descriptor:Monoglyceride lipase, (2-cyclohexyl-1,3-benzoxazol-6-yl){3-[4-(pyrimidin-2-yl)piperazin-1-yl]azetidin-1-yl}methanone
Authors:Schubert, C., Schalk-Hih, C.
Deposit date:2010-10-25
Release date:2011-03-02
Last modified:2013-06-19
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Crystal structure of a soluble form of human monoglyceride lipase in complex with an inhibitor at 1.35 A resolution.
Protein Sci., 20, 2011
4IBM
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CRYSTAL STRUCTURE OF INSULIN RECEPTOR KINASE DOMAIN IN COMPLEX WITH AN INHIBITOR IRFIN-1
Descriptor:Insulin receptor, 5-(2-phenylpyrazolo[1,5-a]pyridin-3-yl)-3H-pyrazolo[3,4-c]pyridazin-3-one
Authors:Wu, J., Anastassiadis, T., Duong-Ly, K.C., Peterson, J.R.
Deposit date:2012-12-08
Release date:2013-08-21
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:A highly selective dual insulin receptor (IR)/insulin-like growth factor 1 receptor (IGF-1R) inhibitor derived from an extracellular signal-regulated kinase (ERK) inhibitor.
J.Biol.Chem., 288, 2013
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