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4CMP
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BU of 4cmp by Molmil
Crystal structure of S. pyogenes Cas9
Descriptor: CRISPR-ASSOCIATED ENDONUCLEASE CAS9/CSN1, MAGNESIUM ION, SULFATE ION
Authors:Jinek, M, Jiang, F, Taylor, D.W, Sternberg, S.H, Kaya, E, Ma, E, Anders, C, Hauer, M, Zhou, K, Lin, S, Kaplan, M, Iavarone, A.T, Charpentier, E, Nogales, E, Doudna, J.A.
Deposit date:2014-01-16
Release date:2014-02-12
Last modified:2014-03-26
Method:X-RAY DIFFRACTION (2.62 Å)
Cite:Structures of Cas9 Endonucleases Reveal RNA-Mediated Conformational Activation.
Science, 343, 2014
4CMQ
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BU of 4cmq by Molmil
Crystal structure of Mn-bound S.pyogenes Cas9
Descriptor: CRISPR-ASSOCIATED ENDONUCLEASE CAS9/CSN1, MANGANESE (II) ION, SULFATE ION
Authors:Jinek, M, Jiang, F, Taylor, D.W, Sternberg, S.H, Kaya, E, Ma, E, Anders, C, Hauer, M, Zhou, K, Lin, S, Kaplan, M, Iavarone, A.T, Charpentier, E, Nogales, E, Doudna, J.A.
Deposit date:2014-01-17
Release date:2014-02-12
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.09 Å)
Cite:Structures of Cas9 Endonucleases Reveal RNA- Mediated Conformational Activation
Science, 343, 2014
4OGC
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BU of 4ogc by Molmil
Crystal structure of the Type II-C Cas9 enzyme from Actinomyces naeslundii
Descriptor: ACETATE ION, HNH endonuclease domain protein, MAGNESIUM ION, ...
Authors:Jiang, F, Ma, E, Lin, S, Doudna, J.A.
Deposit date:2014-01-15
Release date:2014-02-12
Last modified:2014-03-26
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structures of Cas9 endonucleases reveal RNA-mediated conformational activation.
Science, 343, 2014
4OGE
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BU of 4oge by Molmil
Crystal structure of the Type II-C Cas9 enzyme from Actinomyces naeslundii
Descriptor: HNH endonuclease domain protein, MAGNESIUM ION, SPERMIDINE, ...
Authors:Jiang, F, Ma, E, Lin, S, Doudna, J.A.
Deposit date:2014-01-15
Release date:2014-02-12
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.201 Å)
Cite:Structures of Cas9 endonucleases reveal RNA-mediated conformational activation.
Science, 343, 2014
5VGB
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BU of 5vgb by Molmil
Crystal structure of NmeCas9 HNH domain bound to anti-CRISPR AcrIIC1
Descriptor: Anti-CRISPR protein (AcrIIC1), CRISPR-associated endonuclease Cas9, GLYCEROL, ...
Authors:Harrington, L.B, Doxzen, K.W, Ma, E, Knott, G.J, Kranzusch, P.J, Doudna, J.A.
Deposit date:2017-04-10
Release date:2017-08-30
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.497 Å)
Cite:A Broad-Spectrum Inhibitor of CRISPR-Cas9.
Cell, 170, 2017
6NY3
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BU of 6ny3 by Molmil
CasX ternary complex with 30bp target DNA
Descriptor: CasX, DNA Non-target strand, DNA target strand, ...
Authors:Liu, J.J, Orlova, N, Nogales, E, Doudna, J.A.
Deposit date:2019-02-10
Release date:2019-02-27
Last modified:2019-12-25
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:CasX enzymes comprise a distinct family of RNA-guided genome editors.
Nature, 566, 2019
6NY2
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BU of 6ny2 by Molmil
CasX-gRNA-DNA(45bp) state I
Descriptor: CasX, DNA Non-target strand, DNA target strand, ...
Authors:Liu, J.J, Orlova, N, Nogales, E, Doudna, J.A.
Deposit date:2019-02-10
Release date:2019-02-27
Last modified:2019-12-25
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:CasX enzymes comprise a distinct family of RNA-guided genome editors.
Nature, 566, 2019
6NY1
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BU of 6ny1 by Molmil
CasX-gRNA-DNA(30bp) State II
Descriptor: CasX, DNA Non-target strand, DNA target strand, ...
Authors:Liu, J.J, Orlova, N, Nogales, E, Doudna, J.A.
Deposit date:2019-02-10
Release date:2019-02-27
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:CasX enzymes comprise a distinct family of RNA-guided genome editors.
Nature, 566, 2019
8J1V
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BU of 8j1v by Molmil
Cryo-EM structure of SARS-CoV2 Omicron BA.5 spike in complex with 8-9D Fabs
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 8-9D heavy chain, 8-9D light chain, ...
Authors:Xiang, Y, Li, R.
Deposit date:2023-04-13
Release date:2023-11-29
Last modified:2023-12-20
Method:ELECTRON MICROSCOPY (3.01 Å)
Cite:A lung-selective delivery of mRNA encoding broadly neutralizing antibody against SARS-CoV-2 infection.
Nat Commun, 14, 2023
8J1T
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BU of 8j1t by Molmil
Local refined cryo-EM structure of Omicron BA.5 RBD in complex with 8-9D Fab
Descriptor: 8-9D heavy chain, 8-9D light chain, Spike protein
Authors:Xiang, Y, Li, R.
Deposit date:2023-04-13
Release date:2023-11-29
Last modified:2023-12-20
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:A lung-selective delivery of mRNA encoding broadly neutralizing antibody against SARS-CoV-2 infection.
Nat Commun, 14, 2023
7K5N
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BU of 7k5n by Molmil
Ligand binding domain (tandem PAS/dCache) of Aeromonas caviae diguanylate cyclase with proline bound
Descriptor: GLYCEROL, PROLINE, Sensor domain-containing diguanylate cyclase
Authors:Sweeney, E.G, Remington, S.J.
Deposit date:2020-09-17
Release date:2021-08-18
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Host-emitted amino acid cues regulate bacterial chemokinesis to enhance colonization.
Cell Host Microbe, 29, 2021

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PDB entries from 2024-03-27

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