4HA7 | |
4HA9 | |
5UM6 | | CRYSTAL STRUCTURE OF S. POMBE UBA1 IN A CLOSED CONFORMATION | | 分子名称: | Ubiquitin-activating enzyme E1 1, SULFATE ION, N-(2-{[(4-chlorophenyl)methyl]disulfanyl}ethyl)decan-1-amine, ... | | 著者 | Lv, Z., Yuan, L., Aldana-Masangkay, G., Atkison, J.H., Chen, Y., Olsen, S.K. | | 登録日 | 2017-01-26 | | 公開日 | 2017-06-14 | | 最終更新日 | 2017-08-02 | | 実験手法 | X-RAY DIFFRACTION (2.794 Å) | | 主引用文献 | Domain alternation and active site remodeling are conserved structural features of ubiquitin E1.
J. Biol. Chem., 292, 2017
|
|
6CWY | | CRYSTAL STRUCTURE OF SUMO E1 IN COMPLEX WITH AN ALLOSTERIC INHIBITOR | | 分子名称: | SUMO-activating enzyme subunit 1, SUMO-activating enzyme subunit 2, GLYCEROL, ... | | 著者 | Lv, Z., Yuan, L., Atkison, J.H., Williams, K.M., Olsen, S.K. | | 登録日 | 2018-04-01 | | 公開日 | 2019-01-16 | | 実験手法 | X-RAY DIFFRACTION (2.462 Å) | | 主引用文献 | Molecular mechanism of a covalent allosteric inhibitor of SUMO E1 activating enzyme.
Nat Commun, 9, 2018
|
|
6CWZ | | CRYSTAL STRUCTURE OF APO SUMO E1 | | 分子名称: | SUMO-activating enzyme subunit 1, SUMO-activating enzyme subunit 2, ZINC ION | | 著者 | Lv, Z., Yuan, L., Atkison, J.H., Williams, K.M., Olsen, S.K. | | 登録日 | 2018-04-01 | | 公開日 | 2019-01-16 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Molecular mechanism of a covalent allosteric inhibitor of SUMO E1 activating enzyme.
Nat Commun, 9, 2018
|
|
6DC6 | | CRYSTAL STRUCTURE OF HUMAN UBIQUITIN ACTIVATING ENZYME E1 (UBA1) IN COMPLEX WITH UBIQUITIN | | 分子名称: | Ubiquitin-like modifier-activating enzyme 1, Ubiquitin, MAGNESIUM ION, ... | | 著者 | Lv, Z., Yuan, L., Williams, K.M., Atkison, J.H., Olsen, S.K. | | 登録日 | 2018-05-04 | | 公開日 | 2018-10-10 | | 最終更新日 | 2018-12-05 | | 実験手法 | X-RAY DIFFRACTION (3.14 Å) | | 主引用文献 | Crystal structure of a human ubiquitin E1-ubiquitin complex reveals conserved functional elements essential for activity.
J. Biol. Chem., 293, 2018
|
|
5JHH | | CRYSTAL STRUCTURE OF THE TERNARY COMPLEX BETWEEN THE HUMAN RHOA, ITS INHIBITOR AND THE DH/PH DOMAIN OF HUMAN ARHGEF11 | | 分子名称: | Rho guanine nucleotide exchange factor 11, Transforming protein RhoA, GLYCEROL, ... | | 著者 | Lv, Z., Wang, R., Ma, L., Miao, Q., Wu, J., Yan, Z., Li, J., Miao, L., Wang, F. | | 登録日 | 2016-04-21 | | 公開日 | 2017-04-26 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystallization and preliminary X-ray crystallographic analysis of a small GTPase RhoA bound with its inhibitor and PDZRhoGEF
To Be Published
|
|
5KNL | | CRYSTAL STRUCTURE OF S. POMBE UBIQUITIN E1 (UBA1) IN COMPLEX WITH UBC15 AND UBIQUITIN | | 分子名称: | Ubiquitin-activating enzyme E1 1, Ubiquitin, Ubiquitin-conjugating enzyme E2 15, ... | | 著者 | Olsen, S.K., Lv, Z., Yuan, L., Williams, K. | | 登録日 | 2016-06-28 | | 公開日 | 2017-02-15 | | 最終更新日 | 2017-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | S. pombe Uba1-Ubc15 Structure Reveals a Novel Regulatory Mechanism of Ubiquitin E2 Activity.
Mol. Cell, 65, 2017
|
|
3UA3 | | CRYSTAL STRUCTURE OF PROTEIN ARGININE METHYLTRANSFERASE PRMT5 IN COMPLEX WITH SAH | | 分子名称: | Protein arginine N-methyltransferase 5, S-ADENOSYL-L-HOMOCYSTEINE | | 著者 | Sun, L., Wang, M., Lv, Z., Yang, N., Liu, Y., Bao, S., Gong, W., Xu, R.M. | | 登録日 | 2011-10-20 | | 公開日 | 2011-12-14 | | 最終更新日 | 2011-12-28 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structural insights into protein arginine symmetric dimethylation by PRMT5
Proc.Natl.Acad.Sci.USA, 108, 2011
|
|
3UA4 | | CRYSTAL STRUCTURE OF PROTEIN ARGININE METHYLTRANSFERASE PRMT5 | | 分子名称: | Protein arginine N-methyltransferase 5, GLYCEROL | | 著者 | Sun, L., Wang, M., Lv, Z., Yang, N., Liu, Y., Bao, S., Gong, W., Xu, R.M. | | 登録日 | 2011-10-21 | | 公開日 | 2011-12-14 | | 最終更新日 | 2011-12-28 | | 実験手法 | X-RAY DIFFRACTION (3.005 Å) | | 主引用文献 | Structural insights into protein arginine symmetric dimethylation by PRMT5
Proc.Natl.Acad.Sci.USA, 108, 2011
|
|
4J0U | | CRYSTAL STRUCTURE OF IFIT5/ISG58 | | 分子名称: | Interferon-induced protein with tetratricopeptide repeats 5 | | 著者 | Liu, Y., Liang, H., Feng, F., Yuan, L., Wang, Y.E., Crowley, C., Lv, Z., Li, J., Zeng, S., Cheng, G. | | 登録日 | 2013-01-31 | | 公開日 | 2013-02-13 | | 実験手法 | X-RAY DIFFRACTION (1.969 Å) | | 主引用文献 | Crystal Structure of IFIT5
To be Published
|
|
5GT9 | | THE X-RAY STRUCTURE OF 7BETA-HYDROXYSTEROID DEHYDROGENASE | | 分子名称: | Oxidoreductase, short chain dehydrogenase/reductase family protein, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | 著者 | Wang, F., Wang, R., Lv, Z., Chen, Q., Huo, X. | | 登録日 | 2016-08-19 | | 公開日 | 2017-05-17 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structure of NADP(+)-bound 7 beta-hydroxysteroid dehydrogenase reveals two cofactor-binding modes
Acta Crystallogr F Struct Biol Commun, 73, 2017
|
|
5TTE | | CRYSTAL STRUCTURE OF AN RBR E3 UBIQUITIN LIGASE IN COMPLEX WITH AN E2-UB THIOESTER INTERMEDIATE MIMIC | | 分子名称: | E3 ubiquitin-protein ligase ARIH1, Ubiquitin-conjugating enzyme E2 L3, ubiquitin, ... | | 著者 | Yuan, L., Lv, Z., Olsen, S.K. | | 登録日 | 2016-11-03 | | 公開日 | 2017-08-23 | | 最終更新日 | 2017-10-25 | | 実験手法 | X-RAY DIFFRACTION (3.501 Å) | | 主引用文献 | Structural insights into the mechanism and E2 specificity of the RBR E3 ubiquitin ligase HHARI.
Nat Commun, 8, 2017
|
|
5TUB | | CRYSTAL STRUCTURE OF THE SHARK TBC1D15 GAP DOMAIN | | 分子名称: | Shark TBC1D15 GTPase-activating Protein | | 著者 | Chen, Y.-N., Wang, W., Cheng, D., Ge, Y., Gu, X., Zhou, X.E., Ye, F., Xu, H.E., Lv, Z. | | 登録日 | 2016-11-05 | | 公開日 | 2017-02-22 | | 最終更新日 | 2017-04-12 | | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | | 主引用文献 | Crystal structure of TBC1D15 GTPase-activating protein (GAP) domain and its activity on Rab GTPases.
Protein Sci., 26, 2017
|
|
5TUC | | CRYSTAL STRUCTURE OF THE SUS TBC1D15 GAP DOMAIN | | 分子名称: | Sus TBC1D15 GAP Domain | | 著者 | Chen, Y.-N., Wang, W., Cheng, D., Ge, Y., Gu, X., Zhou, X.E., Ye, F., Xu, H.E., Lv, Z. | | 登録日 | 2016-11-05 | | 公開日 | 2017-02-22 | | 最終更新日 | 2017-04-12 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal structure of TBC1D15 GTPase-activating protein (GAP) domain and its activity on Rab GTPases.
Protein Sci., 26, 2017
|
|
3EBJ | | CRYSTAL STRUCTURE OF AN AVIAN INFLUENZA VIRUS PROTEIN | | 分子名称: | Polymerase acidic protein, MAGNESIUM ION | | 著者 | Yuan, P., Bartlam, M., Lou, Z., Chen, S., Rao, Z., Liu, Y. | | 登録日 | 2008-08-27 | | 公開日 | 2009-02-10 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystal structure of an avian influenza polymerase PA(N) reveals an endonuclease active site
Nature, 458, 2009
|
|
5JHG | | CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN THE HUMAN RHOA AND THE DH/PH DOMAIN OF HUMAN ARHGEF11 | | 分子名称: | Rho guanine nucleotide exchange factor 11, Transforming protein RhoA, GLYCEROL | | 著者 | Wang, R., Chen, Q., Zhang, H., Yan, Z., Li, J., Miao, L., Wang, F. | | 登録日 | 2016-04-21 | | 公開日 | 2017-04-26 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystallization and preliminary X-ray crystallographic analysis of a small GTPase RhoA bound with its inhibitor and ARHGEF11
To Be Published
|
|
