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3N3Z
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CRYSTAL STRUCTURE OF PDE9A (E406A) MUTANT IN COMPLEX WITH IBMX
Descriptor:High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A, 3-ISOBUTYL-1-METHYLXANTHINE, ZINC ION, ...
Authors:Hou, J., Luo, H.-B., Chen, Y., Xu, J., Zhao, R., Zou, L.
Deposit date:2010-05-21
Release date:2011-04-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Crystal structure of PDE9A (E406A) mutation in complex with IBMX
To be Published
3EEF
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CRYSTAL STRUCTURE OF N-CARBAMOYLSARCOSINE AMIDASE FROM THERMOPLASMA ACIDOPHILUM
Descriptor:N-carbamoylsarcosine amidase related protein, ZINC ION
Authors:Luo, H.-B., Zheng, H., Chruszcz, M., Zimmerman, M.D., Skarina, T., Egorova, O., Savchenko, A., Joachimiak, A., Minor, W., Midwest Center for Structural Genomics (MCSG)
Deposit date:2008-09-04
Release date:2008-09-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Crystal structure and molecular modeling study of N-carbamoylsarcosine amidase Ta0454 from Thermoplasma acidophilum.
J.Struct.Biol., 169, 2010
3ICC
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CRYSTAL STRUCTURE OF A PUTATIVE 3-OXOACYL-(ACYL CARRIER PROTEIN) REDUCTASE FROM BACILLUS ANTHRACIS AT 1.87 A RESOLUTION
Descriptor:Putative 3-oxoacyl-(acyl carrier protein) reductase, CHLORIDE ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Hou, J., Chruszcz, M., Zheng, H., Cymborowski, M., Luo, H.-B., Skarina, T., Gordon, S., Savchenko, A., Edwards, A.M., Anderson, W., Minor, W., Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2009-07-17
Release date:2009-07-28
Last modified:2012-12-26
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:Structure of a short-chain dehydrogenase/reductase from Bacillus anthracis.
Acta Crystallogr.,Sect.F, 68, 2012
3V4E
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CRYSTAL STRUCTURE OF THE GALACTOSIDE O-ACETYLTRANSFERASE IN COMPLEX WITH COA
Descriptor:Galactoside O-acetyltransferase, DI(HYDROXYETHYL)ETHER, TRIETHYLENE GLYCOL, ...
Authors:Knapik, A.A., Shumilin, I.A., Luo, H.-B., Chruszcz, M., Zimmerman, M.D., Cymborowski, M., Anderson, W.F., Minor, W., Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2011-12-14
Release date:2012-01-11
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Biophysical analysis of the putative acetyltransferase SACOL2570 from methicillin-resistant Staphylococcus aureus.
J.Struct.Funct.Genom., 14, 2013
6KJZ
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CRYSTAL STRUCTURE OF PDE4D CATALYTIC DOMAIN COMPLEXED WITH COMPOUND 1
Descriptor:cAMP-specific 3',5'-cyclic phosphodiesterase 4D, ZINC ION, MAGNESIUM ION, ...
Authors:Huang, Y.-Y., He, X., Luo, H.-B.
Deposit date:2019-07-23
Release date:2020-03-18
Last modified:2020-05-13
Method:X-RAY DIFFRACTION (2.200001 Å)
Cite:Discovery and Optimization of alpha-Mangostin Derivatives as Novel PDE4 Inhibitors for the Treatment of Vascular Dementia.
J.Med.Chem., 63, 2020
6KK0
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CRYSTAL STRUCTURE OF PDE4D CATALYTIC DOMAIN COMPLEXED WITH COMPOUND 4E
Descriptor:cAMP-specific 3',5'-cyclic phosphodiesterase 4D, 7-[8-methoxy-2,2-dimethyl-7-(3-methylbut-2-enyl)-5-oxidanyl-6-oxidanylidene-pyrano[3,2-b]xanthen-9-yl]oxyheptanoic acid, ZINC ION, ...
Authors:Huang, Y.-Y., He, X., Luo, H.-B.
Deposit date:2019-07-23
Release date:2020-03-18
Last modified:2020-05-13
Method:X-RAY DIFFRACTION (2.200088 Å)
Cite:Discovery and Optimization of alpha-Mangostin Derivatives as Novel PDE4 Inhibitors for the Treatment of Vascular Dementia.
J.Med.Chem., 63, 2020
6KO0
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THE CRYSTAL STRUCTUE OF PDE10A COMPLEXED WITH 1I
Descriptor:cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A, 3-[2-(5-methyl-1-phenyl-benzimidazol-2-yl)ethyl]chromen-4-one, ZINC ION, ...
Authors:Huang, Y.-Y., Yu, Y.F., Zhang, C., Guo, L., Wu, D., Luo, H.-B.
Deposit date:2019-08-07
Release date:2020-04-01
Last modified:2020-04-15
Method:X-RAY DIFFRACTION (2.600029 Å)
Cite:Discovery and Optimization of Chromone Derivatives as Novel Selective Phosphodiesterase 10 Inhibitors.
Acs Chem Neurosci, 11, 2020
6KO1
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THE CRYSTAL STRUCTUE OF PDE10A COMPLEXED WITH 2D
Descriptor:cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A, ZINC ION, MAGNESIUM ION, ...
Authors:Huang, Y.-Y., Yu, Y.F., Zhang, C., Guo, L., Wu, D., Luo, H.-B.
Deposit date:2019-08-07
Release date:2020-04-01
Last modified:2020-04-15
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Discovery and Optimization of Chromone Derivatives as Novel Selective Phosphodiesterase 10 Inhibitors.
Acs Chem Neurosci, 11, 2020
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PDB entries from 2020-08-12