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Structure of human DPP-IV with (2S,3S,11bS)-3-(3-Fluoromethyl-phenyl)-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-ylamine
Descriptor:	(2S,3S,11bS)-3-[3-(fluoromethyl)phenyl]-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-amine, 2-acetamido-2-deoxy-beta-D-glucopyranose, Dipeptidyl peptidase 4 soluble form
Authors:	Hennig, M, Stihle, M, Thoma, R.
Deposit date:	2009-12-01
Release date:	2010-09-15
Last modified:	2020-09-09
Method:	X-RAY DIFFRACTION (2.8 Å)
Cite:	Aryl- and heteroaryl-substituted aminobenzo[a]quinolizines as dipeptidyl peptidase IV inhibitors. Bioorg.Med.Chem.Lett., 20, 2010

NMR derived model of the 5'-splice site of SMN2 in complex with the 5'-end of U1 snRNA
Descriptor:	RNA (5'-R(PAPUPAPCP(PSU)P(PSU)PAPCPCPUPG)-3'), RNA (5'-R(PGPGPAPGPUPAPAPGPUPCPU)-3')
Authors:	Campagne, S, Clery, A, Allain, F.H.
Deposit date:	2017-08-14
Release date:	2017-08-30
Last modified:	2023-06-14
Method:	SOLUTION NMR
Cite:	Binding to SMN2 pre-mRNA-protein complex elicits specificity for small molecule splicing modifiers. Nat Commun, 8, 2017

Human Dipeptidyl peptidase IV in complex with 1-(3,4-Dimethoxy-phenyl) -3-m-tolyl-piperidine-4-ylamine
Descriptor:	(3R,4S)-1-(3,4-DIMETHOXYPHENYL)-3-(3-METHYLPHENYL)PIPERIDIN-4-AMINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, DIPEPTIDYL PEPTIDASE 4
Authors:	Hennig, M, Stihle, M, Luebbers, T, Thoma, R.
Deposit date:	2007-02-28
Release date:	2008-05-27
Last modified:	2020-07-29
Method:	X-RAY DIFFRACTION (2.8 Å)
Cite:	1,3-Disubstituted 4-Aminopiperidines as Useful Tools in the Optimization of the 2-Aminobenzo[A]Quinolizine Dipeptidyl Peptidase Iv Inhibitors. Bioorg.Med.Chem.Lett., 17, 2007