Author results

5VGZ
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CONFORMATIONAL LANDSCAPE OF THE P28-BOUND HUMAN PROTEASOME REGULATORY PARTICLE
分子名称:26S proteasome regulatory subunit 7, 26S proteasome regulatory subunit 4, 26S proteasome regulatory subunit 8, ...
著者Lu, Y., Wu, J., Dong, Y., Chen, S., Sun, S., Ma, Y.B., Ouyang, Q., Finley, D., Kirschner, M.W., Mao, Y.
登録日2017-04-12
公開日2017-08-23
最終更新日2018-08-22
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle.
Mol. Cell, 67, 2017
5VHF
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CONFORMATIONAL LANDSCAPE OF THE P28-BOUND HUMAN PROTEASOME REGULATORY PARTICLE
分子名称:26S proteasome non-ATPase regulatory subunit 10, 26S proteasome regulatory subunit 7, 26S proteasome regulatory subunit 4, ...
著者Lu, Y., Wu, J., Dong, Y., Chen, S., Sun, S., Ma, Y.B., Ouyang, Q., Finley, D., Kirschner, M.W., Mao, Y.
登録日2017-04-13
公開日2017-08-23
最終更新日2018-08-22
実験手法ELECTRON MICROSCOPY (5.7 Å)
主引用文献Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle.
Mol. Cell, 67, 2017
5VHH
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CONFORMATIONAL LANDSCAPE OF THE P28-BOUND HUMAN PROTEASOME REGULATORY PARTICLE
分子名称:26S proteasome regulatory subunit 7, 26S proteasome regulatory subunit 4, 26S proteasome regulatory subunit 8, ...
著者Lu, Y., Wu, J., Dong, Y., Chen, S., Sun, S., Ma, Y.B., Ouyang, Q., Finley, D., Kirschner, M.W., Mao, Y.
登録日2017-04-13
公開日2017-08-23
最終更新日2018-08-22
実験手法ELECTRON MICROSCOPY (6.1 Å)
主引用文献Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle.
Mol. Cell, 67, 2017
5VHI
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CONFORMATIONAL LANDSCAPE OF THE P28-BOUND HUMAN PROTEASOME REGULATORY PARTICLE
分子名称:26S proteasome regulatory subunit 7, 26S proteasome regulatory subunit 4, 26S proteasome regulatory subunit 8, ...
著者Lu, Y., Wu, J., Dong, Y., Chen, S., Sun, S., Ma, Y.B., Ouyang, Q., Finley, D., Kirschner, M.W., Mao, Y.
登録日2017-04-13
公開日2017-08-23
最終更新日2018-08-22
実験手法ELECTRON MICROSCOPY (6.8 Å)
主引用文献Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle.
Mol. Cell, 67, 2017
5VHJ
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CONFORMATIONAL LANDSCAPE OF THE P28-BOUND HUMAN PROTEASOME REGULATORY PARTICLE
分子名称:26S proteasome non-ATPase regulatory subunit 10, 26S proteasome regulatory subunit 7, 26S proteasome regulatory subunit 4, ...
著者Lu, Y., Wu, J., Dong, Y., Chen, S., Sun, S., Ma, Y.B., Ouyang, Q., Finley, D., Kirschner, M.W., Mao, Y.
登録日2017-04-13
公開日2017-08-23
最終更新日2018-08-22
実験手法ELECTRON MICROSCOPY (8.5 Å)
主引用文献Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle.
Mol. Cell, 67, 2017
5VHM
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CONFORMATIONAL LANDSCAPE OF THE P28-BOUND HUMAN PROTEASOME REGULATORY PARTICLE
分子名称:26S proteasome non-ATPase regulatory subunit 10, 26S proteasome regulatory subunit 7, 26S proteasome regulatory subunit 4, ...
著者Lu, Y., Wu, J., Dong, Y., Chen, S., Sun, S., Ma, Y.B., Ouyang, Q., Finley, D., Kirschner, M.W., Mao, Y.
登録日2017-04-13
公開日2017-08-23
最終更新日2018-09-12
実験手法ELECTRON MICROSCOPY (8.3 Å)
主引用文献Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle.
Mol. Cell, 67, 2017
5VHN
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CONFORMATIONAL LANDSCAPE OF THE P28-BOUND HUMAN PROTEASOME REGULATORY PARTICLE
分子名称:26S proteasome non-ATPase regulatory subunit 10, 26S proteasome regulatory subunit 7, 26S proteasome regulatory subunit 4, ...
著者Lu, Y., Wu, J., Dong, Y., Chen, S., Sun, S., Ma, Y.B., Ouyang, Q., Finley, D., Kirschner, M.W., Mao, Y.
登録日2017-04-13
公開日2017-08-23
最終更新日2018-08-22
実験手法ELECTRON MICROSCOPY (7.3 Å)
主引用文献Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle.
Mol. Cell, 67, 2017
5VHO
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CONFORMATIONAL LANDSCAPE OF THE P28-BOUND HUMAN PROTEASOME REGULATORY PARTICLE
分子名称:26S proteasome non-ATPase regulatory subunit 10, 26S proteasome regulatory subunit 7, 26S proteasome regulatory subunit 4, ...
著者Lu, Y., Wu, J., Dong, Y., Chen, S., Sun, S., Ma, Y.B., Ouyang, Q., Finley, D., Kirschner, M.W., Mao, Y.
登録日2017-04-13
公開日2017-08-23
最終更新日2018-08-22
実験手法ELECTRON MICROSCOPY (8.3 Å)
主引用文献Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle.
Mol. Cell, 67, 2017
5VHP
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CONFORMATIONAL LANDSCAPE OF THE P28-BOUND HUMAN PROTEASOME REGULATORY PARTICLE
分子名称:26S proteasome non-ATPase regulatory subunit 10, 26S proteasome regulatory subunit 7, 26S proteasome regulatory subunit 4, ...
著者Lu, Y., Wu, J., Dong, Y., Chen, S., Sun, S., Ma, Y.B., Ouyang, Q., Finley, D., Kirschner, M.W., Mao, Y.
登録日2017-04-13
公開日2017-08-23
最終更新日2018-08-22
実験手法ELECTRON MICROSCOPY (7.9 Å)
主引用文献Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle.
Mol. Cell, 67, 2017
5VHQ
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CONFORMATIONAL LANDSCAPE OF THE P28-BOUND HUMAN PROTEASOME REGULATORY PARTICLE
分子名称:26S proteasome non-ATPase regulatory subunit 10, 26S proteasome regulatory subunit 7, 26S proteasome regulatory subunit 4, ...
著者Lu, Y., Wu, J., Dong, Y., Chen, S., Sun, S., Ma, Y.B., Ouyang, Q., Finley, D., Kirschner, M.W., Mao, Y.
登録日2017-04-13
公開日2017-08-23
最終更新日2018-08-22
実験手法ELECTRON MICROSCOPY (8.9 Å)
主引用文献Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle.
Mol. Cell, 67, 2017
5VHR
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CONFORMATIONAL LANDSCAPE OF THE P28-BOUND HUMAN PROTEASOME REGULATORY PARTICLE
分子名称:26S proteasome non-ATPase regulatory subunit 10, 26S proteasome regulatory subunit 7, 26S proteasome regulatory subunit 4, ...
著者Lu, Y., Wu, J., Dong, Y., Chen, S., Sun, S., Ma, Y.B., Ouyang, Q., Finley, D., Kirschner, M.W., Mao, Y.
登録日2017-04-13
公開日2017-08-23
最終更新日2018-08-22
実験手法ELECTRON MICROSCOPY (7.7 Å)
主引用文献Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle.
Mol. Cell, 67, 2017
5VHS
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CONFORMATIONAL LANDSCAPE OF THE P28-BOUND HUMAN PROTEASOME REGULATORY PARTICLE
分子名称:26S proteasome regulatory subunit 7, 26S proteasome regulatory subunit 4, 26S proteasome regulatory subunit 8, ...
著者Lu, Y., Wu, J., Dong, Y., Chen, S., Sun, S., Ma, Y.B., Ouyang, Q., Finley, D., Kirschner, M.W., Mao, Y.
登録日2017-04-13
公開日2017-08-23
最終更新日2018-08-22
実験手法ELECTRON MICROSCOPY (8.8 Å)
主引用文献Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle.
Mol. Cell, 67, 2017
5WZX
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STRUCTURAL BASIS FOR A PENTACYCLIC OLEANANE-TYPE TRITERPENOID AS A LIGAND OF FXR
分子名称:Bile acid receptor, SRC2-3 peptide from Nuclear receptor coactivator 2, (4aR,6aR,6aS,6bS,8aS,9R,12aR,14bR)-2,2,6a,6b,9,12a-hexamethyl-10-oxidanylidene-1,3,4,5,6,6a,7,8,8a,9,11,12,13,14b-tetradecahydropicene-4a-carboxylic acid, ...
著者Lu, Y., Li, Y.
登録日2017-01-19
公開日2018-01-03
最終更新日2018-01-17
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Identification of an Oleanane-Type Triterpene Hedragonic Acid as a Novel Farnesoid X Receptor Ligand with Liver Protective Effects and Anti-inflammatory Activity
Mol. Pharmacol., 93, 2018
6UH3
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CRYSTAL STRUCTURE OF BACTERIAL HELIORHODOPSIN 48C12
分子名称:Heliorhodopsin, RETINAL, TRIETHYLENE GLYCOL, ...
著者Lu, Y., Zhou, X.E., Gao, X., Xia, R., Xu, Z., Wang, N., Leng, Y., Melcher, K., Xu, H.E., He, Y.
登録日2019-09-26
公開日2019-12-04
最終更新日2019-12-11
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structure of bacterial heliorhodopsin 48C12
To Be Published
5Y1J
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CRYSTAL STRUCTURE OF HUMAN FXR IN COMPLEX WITH A FUNCTIONAL DRUG LIGAND
分子名称:Bile acid receptor, Peptide from Nuclear receptor coactivator 2, 2-[[2-fluoranyl-4-(3-methoxyphenyl)phenyl]carbamoyl]cyclopentene-1-carboxylic acid
著者Lu, Y., Li, Y.
登録日2017-07-20
公開日2018-10-31
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of human FXR in complex with a functional drug liagnd
To Be Published
5Y44
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A NOVEL MODERATOR XD4 FOR BILE ACID RECEPTOR
分子名称:Bile acid receptor, Peptide from Nuclear receptor coactivator 1, [(1R,2R,4R)-1,7,7-trimethyl-2-bicyclo[2.2.1]heptanyl] 4-azanyl-3-methyl-benzoate, ...
著者Lu, Y., Li, Y.
登録日2017-08-01
公開日2019-02-20
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献A novel moderator XD4 for bile acid receptor
To Be Published
5Y49
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A MODERATOR XD22 BINDING TO BILE ACID RECEPTOR
分子名称:Bile acid receptor, Peptide from Nuclear receptor coactivator 2, [(1R,2S,4S)-2-bicyclo[2.2.1]heptanyl] 4-azanylbenzoate
著者Lu, Y., Li, Y.
登録日2017-08-02
公開日2019-02-20
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献A moderator XD22 binding to bile acid receptor
To Be Published
3K3P
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CRYSTAL STRUCTURE OF THE APO FORM OF D-ALANINE:D-ALANINE LIGASE (DDL) FROM STREPTOCOCCUS MUTANS
分子名称:D-alanine--D-alanine ligase
著者Lu, Y.
登録日2009-10-03
公開日2010-09-15
最終更新日2019-10-16
実験手法X-RAY DIFFRACTION (2.23 Å)
主引用文献Crystal structure of the Apo form of D-Alanine:D-Alanine ligase (DDl) from Streptococcus mutans.
Protein Pept.Lett., 17, 2010
5XQ5
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NMR STRUCTURE OF THE DOMAIN 5 OF THE E. COLI RIBOSOMAL PROTEIN S1
分子名称:30S ribosomal protein S1
著者Lu, Y., Lim, L.Z., Song, J.
登録日2017-06-06
公開日2018-06-06
実験手法SOLUTION NMR
主引用文献NMR structure of the domain 5 of the E. coli ribosomal protein S1
To Be Published
5IAW
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NOVEL NATURAL FXR MODULATOR WITH A UNIQUE BINDING MODE
分子名称:Bile acid receptor, Peptide from Nuclear receptor coactivator 2, (1S,2R,4S)-1,7,7-trimethylbicyclo[2.2.1]heptan-2-yl 4-hydroxybenzoate
著者Lu, Y., Li, Y.
登録日2016-02-22
公開日2017-03-08
最終更新日2017-05-03
実験手法X-RAY DIFFRACTION (2.58 Å)
主引用文献A Novel Class of Natural FXR Modulators with a Unique Mode of Selective Co-regulator Assembly
Chembiochem, 18, 2017
5ICK
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A UNIQUE BINDING MODEL OF FXR LBD WITH FEROLINE
分子名称:Bile acid receptor, Nuclear receptor coactivator 2, (1S,2S,3Z,5S,8Z)-5-hydroxy-5,9-dimethyl-2-(propan-2-yl)cyclodeca-3,8-dien-1-yl 4-hydroxybenzoate
著者Lu, Y., Li, Y.
登録日2016-02-23
公開日2017-03-08
最終更新日2017-08-30
実験手法X-RAY DIFFRACTION (2.47 Å)
主引用文献A Novel Class of Natural FXR Modulators with a Unique Mode of Selective Co-regulator Assembly
Chembiochem, 18, 2017
5Z12
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A STRUCTURE OF FXR/RXR
分子名称:Bile acid receptor, Retinoic acid receptor RXR-alpha, Peptide from Nuclear receptor coactivator 2, ...
著者Lu, Y., Li, Y.
登録日2017-12-23
公開日2018-07-04
最終更新日2018-08-22
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Structural insights into the heterodimeric complex of the nuclear receptors FXR and RXR
J. Biol. Chem., 293, 2018
4FQ5
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CRYSTAL STRUCTURE OF THE MALEATE ISOMERASE ISO(C200A) FROM PSEUDOMONAS PUTIDA S16 WITH MALEATE
分子名称:Maleate cis-trans isomerase, MALEIC ACID
著者Lu, Y., Chen, D., Zhang, Z., Li, Q., Wu, G., Xu, P.
登録日2012-06-25
公開日2013-07-24
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural and computational studies of the maleate isomerase from Pseudomonas putida S16 reveal a breathing motion wrapping the substrate inside.
Mol.Microbiol., 87, 2013
4FQ7
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CRYSTAL STRUCTURE OF THE MALEATE ISOMERASE ISO FROM PSEUDOMONAS PUTIDA S16
分子名称:Maleate cis-trans isomerase
著者Lu, Y., Chen, D., Zhang, Z., Li, Q., Wu, G., Xu, P.
登録日2012-06-25
公開日2013-07-24
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural and computational studies of the maleate isomerase from Pseudomonas putida S16 reveal a breathing motion wrapping the substrate inside.
Mol.Microbiol., 87, 2013
2FDP
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CRYSTAL STRUCTURE OF BETA-SECRETASE COMPLEXED WITH AN AMINO-ETHYLENE INHIBITOR
分子名称:Beta-secretase 1, N1-((2S,3S,5R)-3-AMINO-6-(4-FLUOROPHENYLAMINO)-5-METHYL-6-OXO-1-PHENYLHEXAN-2-YL)-N3,N3-DIPROPYLISOPHTHALAMIDE
著者Yang, W., Lu, W., Lu, Y., Zhong, M., Sun, J., Thomas, A.E., Wilkinson, J.M., Fucini, R.V., Lam, M., Randal, M., Shi, X.P., Jacobs, J.W., McDowell, R.S., Gordon, E.M., Ballinger, M.D.
登録日2005-12-14
公開日2006-01-24
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Aminoethylenes: a tetrahedral intermediate isostere yielding potent inhibitors of the aspartyl protease BACE-1.
J.Med.Chem., 49, 2006