7KXI
 
 | | Structure of XL5-ligated hRpn13 Pru domain | | Descriptor: | 2-{[(2S)-2-cyano-3-{3-[(4-methylbenzene-1-carbonyl)amino]phenyl}propanoyl]amino}benzoic acid, Proteasomal ubiquitin receptor ADRM1 | | Authors: | Lu, X, Walters, K.J. | | Deposit date: | 2020-12-03 | | Release date: | 2021-12-15 | | Last modified: | 2021-12-29 | | Method: | SOLUTION NMR | | Cite: | Structure-guided bifunctional molecules hit a DEUBAD-lacking hRpn13 species upregulated in multiple myeloma.
Nat Commun, 12, 2021
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3C1B
 | | The effect of H3 K79 dimethylation and H4 K20 trimethylation on nucleosome and chromatin structure | | Descriptor: | Histone 2, H2bf, Histone H2A type 1, ... | | Authors: | Lu, X, Simon, M, Chodaparambil, J, Hansen, J, Shokat, K, Luger, K. | | Deposit date: | 2008-01-22 | | Release date: | 2008-10-07 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | The effect of H3K79 dimethylation and H4K20 trimethylation on nucleosome and chromatin structure.
Nat.Struct.Mol.Biol., 15, 2008
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3C1C
 | | The effect of H3 K79 dimethylation and H4 K20 trimethylation on nucleosome and chromatin structure | | Descriptor: | Histone 2, H2bf, Histone H2A type 1, ... | | Authors: | Lu, X, Simon, M, Chodaparambil, J, Hansen, J, Shokat, K, Luger, K. | | Deposit date: | 2008-01-22 | | Release date: | 2008-10-07 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (3.15 Å) | | Cite: | The effect of H3K79 dimethylation and H4K20 trimethylation on nucleosome and chromatin structure.
Nat.Struct.Mol.Biol., 15, 2008
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4ROW
 | | The crystal structure of novel APOBEC3G CD2 head-to-tail dimer suggests the binding mode of full-length APOBEC3G to HIV-1 ssDNA | | Descriptor: | DNA dC->dU-editing enzyme APOBEC-3G, ZINC ION | | Authors: | Lu, X, Zhang, T, Xu, Z, Liu, S, Zhao, B, Lan, W, Wang, C, Ding, J, Cao, C. | | Deposit date: | 2014-10-29 | | Release date: | 2014-12-31 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Crystal structure of DNA cytidine deaminase ABOBEC3G catalytic deamination domain suggests a binding mode of full-length enzyme to single-stranded DNA
J.Biol.Chem., 290, 2015
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4ROV
 | | The crystal structure of novel APOBEC3G CD2 head-to-tail dimer suggests the binding mode of full-length APOBEC3G to HIV-1 ssDNA | | Descriptor: | DNA dC->dU-editing enzyme APOBEC-3G, ZINC ION | | Authors: | Lu, X, Zhang, T, Xu, Z, Liu, S, Zhao, B, Lan, W, Wang, C, Ding, J, Cao, C. | | Deposit date: | 2014-10-29 | | Release date: | 2014-12-31 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Crystal structure of DNA cytidine deaminase ABOBEC3G catalytic deamination domain suggests a binding mode of full-length enzyme to single-stranded DNA
J.Biol.Chem., 290, 2015
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4EOT
 | | Crystal structure of the MafA homodimer bound to the consensus MARE | | Descriptor: | 5'-D(*CP*CP*CP*TP*GP*CP*TP*GP*AP*CP*TP*CP*AP*GP*CP*AP*CP*CP*G)-3', 5'-D(*CP*CP*GP*GP*TP*GP*CP*TP*GP*AP*GP*TP*CP*AP*GP*CP*AP*GP*G)-3', SULFATE ION, ... | | Authors: | Lu, X, Guanga, G, Wan, C, Rose, R.B. | | Deposit date: | 2012-04-15 | | Release date: | 2012-11-28 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.855 Å) | | Cite: | A Novel DNA Binding Mechanism for maf Basic Region-Leucine Zipper Factors Inferred from a MafA-DNA Complex Structure and Binding Specificities.
Biochemistry, 51, 2012
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4F23
 | | Influenza A virus hemagglutinin H16 HA0 structure with an alpha-helix conformation in the cleavage site: a potential drug target | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin | | Authors: | Lu, X, Shi, Y, Gao, F, Xiao, H, Qi, J, Gao, G.F. | | Deposit date: | 2012-05-07 | | Release date: | 2012-11-21 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Insights into Avian Influenza Virus Pathogenicity: the Hemagglutinin Precursor HA0 of Subtype H16 Has an Alpha-Helix Structure in Its Cleavage Site with Inefficient HA1/HA2 Cleavage.
J.Virol., 86, 2012
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4FIU
 | | The structure of hemagglutinin of H16 subtype influenza virus with V327G mutation | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, hemagglutinin | | Authors: | Lu, X, Shi, Y, Gao, F, Xiao, H, Wang, M, Qi, J, Gao, G.F. | | Deposit date: | 2012-06-11 | | Release date: | 2012-11-21 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (1.999 Å) | | Cite: | Insights into Avian Influenza Virus Pathogenicity: the Hemagglutinin Precursor HA0 of Subtype H16 Has an Alpha-Helix Structure in Its Cleavage Site with Inefficient HA1/HA2 Cleavage.
J.Virol., 86, 2012
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2R7Q
 | | Crystal Structure of VP1 apoenzyme of Rotavirus SA11 (C-terminal hexahistidine-tagged) | | Descriptor: | RNA-dependent RNA polymerase | | Authors: | Lu, X, Harrison, S.C, Tao, Y.J, Patton, J.T, Nibert, M.L. | | Deposit date: | 2007-09-09 | | Release date: | 2008-07-29 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Mechanism for coordinated RNA packaging and genome replication by rotavirus polymerase VP1.
Structure, 16, 2008
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2R7R
 | | Crystal Structure of Rotavirus SA11 VP1/RNA (UGUGACC) complex | | Descriptor: | RNA (5'-R(*UP*GP*UP*GP*AP*CP*C)-3'), RNA-dependent RNA polymerase | | Authors: | Lu, X, Harrison, S.C, Tao, Y.J, Patton, J.T, Nibert, M.L. | | Deposit date: | 2007-09-09 | | Release date: | 2008-07-29 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Mechanism for coordinated RNA packaging and genome replication by rotavirus polymerase VP1.
Structure, 16, 2008
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2R7T
 | | Crystal Structure of Rotavirus SA11 VP1/RNA (UGUGAACC) Complex | | Descriptor: | RNA (5'-R(*UP*GP*UP*GP*AP*AP*CP*C)-3'), RNA-dependent RNA polymerase | | Authors: | Lu, X, Harrison, S.C, Tao, Y.J, Patton, J.T, Nibert, M.L. | | Deposit date: | 2007-09-10 | | Release date: | 2008-07-29 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Mechanism for coordinated RNA packaging and genome replication by rotavirus polymerase VP1.
Structure, 16, 2008
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2R7O
 | | Crystal Structure of VP1 apoenzyme of Rotavirus SA11 (N-terminal hexahistidine-tagged) | | Descriptor: | RNA-dependent RNA polymerase | | Authors: | Lu, X, Harrison, S.C, Tao, Y.J, Patton, J.T, Nibert, M.L. | | Deposit date: | 2007-09-09 | | Release date: | 2008-07-29 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (3.35 Å) | | Cite: | Mechanism for coordinated RNA packaging and genome replication by rotavirus polymerase VP1.
Structure, 16, 2008
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2R7S
 | | Crystal Structure of Rotavirus SA11 VP1 / RNA (UGUGCC) complex | | Descriptor: | PHOSPHATE ION, RNA (5'-R(*UP*GP*UP*GP*CP*C)-3'), RNA-dependent RNA polymerase | | Authors: | Lu, X, Harrison, S.C, Tao, Y.J, Patton, J.T, Nibert, M.L. | | Deposit date: | 2007-09-10 | | Release date: | 2008-07-29 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (3.24 Å) | | Cite: | Mechanism for coordinated RNA packaging and genome replication by rotavirus polymerase VP1.
Structure, 16, 2008
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2R7V
 | | Crystal Structure of Rotavirus SA11 VP1/RNA (GGCUUU) Complex | | Descriptor: | RNA (5'-R(*G*GP*CP*UP*UP*U)-3'), RNA-dependent RNA polymerase | | Authors: | Lu, X, Harrison, S.C, Tao, Y.J, Patton, J.T, Nibert, M.L. | | Deposit date: | 2007-09-10 | | Release date: | 2008-07-29 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Mechanism for coordinated RNA packaging and genome replication by rotavirus polymerase VP1.
Structure, 16, 2008
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2R7U
 | | Crystal Structure of Rotavirus SA11 VP1/RNA (AAAAGCC) Complex | | Descriptor: | RNA (5'-R(*AP*A*AP*AP*GP*CP*C)-3'), RNA-dependent RNA polymerase | | Authors: | Lu, X, Harrison, S.C, Tao, Y.J, Patton, J.T, Nibert, M.L. | | Deposit date: | 2007-09-10 | | Release date: | 2008-07-29 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Mechanism for coordinated RNA packaging and genome replication by rotavirus polymerase VP1.
Structure, 16, 2008
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2R7X
 | | Crystal Structure of Rotavirus SA11 VP1/RNA (UGUGACC)/GTP complex | | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, RNA (5'-R(*UP*GP*UP*GP*AP*CP*C)-3'), RNA-dependent RNA polymerase | | Authors: | Lu, X, Harrison, S.C, Tao, Y.J, Patton, J.T, Nibert, M.L. | | Deposit date: | 2007-09-10 | | Release date: | 2008-07-29 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Mechanism for coordinated RNA packaging and genome replication by rotavirus polymerase VP1.
Structure, 16, 2008
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2R7W
 | | Crystal Structure of Rotavirus SA11 VP1/RNA (UGUGACC)/mRNA 5'-CAP (m7GpppG) complex | | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, RNA (5'-R(*UP*GP*UP*GP*AP*CP*C)-3'), RNA-dependent RNA polymerase | | Authors: | Lu, X, Harrison, S.C, Tao, Y.J, Patton, J.T, Nibert, M.L. | | Deposit date: | 2007-09-10 | | Release date: | 2008-07-29 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Mechanism for coordinated RNA packaging and genome replication by rotavirus polymerase VP1.
Structure, 16, 2008
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6UYJ
 | | hRpn13:hRpn2:K48-diubiquitin | | Descriptor: | 26S proteasome non-ATPase regulatory subunit 1, Proteasomal ubiquitin receptor ADRM1, Ubiquitin | | Authors: | Lu, X, Walters, K.J. | | Deposit date: | 2019-11-13 | | Release date: | 2020-03-11 | | Last modified: | 2020-05-20 | | Method: | SOLUTION NMR | | Cite: | An Extended Conformation for K48 Ubiquitin Chains Revealed by the hRpn2:Rpn13:K48-Diubiquitin Structure.
Structure, 28, 2020
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6UYI
 | | hRpn13:hRpn2:K48-diubiquitin | | Descriptor: | 26S proteasome non-ATPase regulatory subunit 1, Proteasomal ubiquitin receptor ADRM1, Ubiquitin | | Authors: | Lu, X, Walters, K.J. | | Deposit date: | 2019-11-13 | | Release date: | 2020-03-11 | | Last modified: | 2022-03-16 | | Method: | SOLUTION NMR | | Cite: | An Extended Conformation for K48 Ubiquitin Chains Revealed by the hRpn2:Rpn13:K48-Diubiquitin Structure.
Structure, 28, 2020
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4KPS
 | | Structure and receptor binding specificity of the hemagglutinin H13 from avian influenza A virus H13N6 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose, ... | | Authors: | Lu, X, Qi, J, Shi, Y, Gao, G. | | Deposit date: | 2013-05-14 | | Release date: | 2013-07-03 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.587 Å) | | Cite: | Structure and Receptor Binding Specificity of Hemagglutinin H13 from Avian Influenza A Virus H13N6
J.Virol., 87, 2013
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4KDO
 | | Crystal structure of the hemagglutinin of ferret-transmissible H5N1 virus in complex with human receptor analog LSTc | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ... | | Authors: | Lu, X, Shi, Y, Zhang, W, Zhang, Y, Qi, J, Gao, G.F. | | Deposit date: | 2013-04-25 | | Release date: | 2013-07-24 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.396 Å) | | Cite: | Structure and receptor-binding properties of an airborne transmissible avian influenza A virus hemagglutinin H5 (VN1203mut).
Protein Cell, 4, 2013
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4KDM
 | | Crystal structure of the hemagglutinin of ferret-transmissible H5N1 virus | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin | | Authors: | Lu, X, Shi, Y, Zhang, W, Zhang, Y, Qi, J, Gao, G.F. | | Deposit date: | 2013-04-25 | | Release date: | 2013-07-24 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.496 Å) | | Cite: | Structure and receptor-binding properties of an airborne transmissible avian influenza A virus hemagglutinin H5 (VN1203mut).
Protein Cell, 4, 2013
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4KPQ
 | | Structure and receptor binding specificity of the hemagglutinin H13 from avian influenza A virus H13N6 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin | | Authors: | Lu, X, Qi, J, Shi, Y, Gao, G. | | Deposit date: | 2013-05-14 | | Release date: | 2013-07-03 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.502 Å) | | Cite: | Structure and Receptor Binding Specificity of Hemagglutinin H13 from Avian Influenza A Virus H13N6
J.Virol., 87, 2013
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4KDN
 | | Crystal structure of the hemagglutinin of ferret-transmissible H5N1 virus in complex with avian receptor analog LSTa | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ... | | Authors: | Lu, X, Shi, Y, Zhang, W, Zhang, Y, Qi, J, Gao, G.F. | | Deposit date: | 2013-04-25 | | Release date: | 2013-07-24 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.483 Å) | | Cite: | Structure and receptor-binding properties of an airborne transmissible avian influenza A virus hemagglutinin H5 (VN1203mut).
Protein Cell, 4, 2013
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4KDQ
 | | Crystal structure of the hemagglutinin of A/Xinjiang/1/2006 virus | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin | | Authors: | Lu, X, Shi, Y, Zhang, W, Zhang, Y, Qi, J, Gao, G.F. | | Deposit date: | 2013-04-25 | | Release date: | 2013-07-24 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.604 Å) | | Cite: | Structure and receptor-binding properties of an airborne transmissible avian influenza A virus hemagglutinin H5 (VN1203mut).
Protein Cell, 4, 2013
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