Author results

1CNE
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STRUCTURAL STUDIES ON CORN NITRATE REDUCTASE: REFINED STRUCTURE OF THE CYTOCHROME B REDUCTASE FRAGMENT AT 2.5 ANGSTROMS, ITS ADP COMPLEX AND AN ACTIVE SITE MUTANT AND MODELING OF THE CYTOCHROME B DOMAIN
Descriptor:NITRATE REDUCTASE, FLAVIN-ADENINE DINUCLEOTIDE
Authors:Lu, G., Lindqvist, Y., Schneider, G.
Deposit date:1995-02-01
Release date:1995-04-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural studies on corn nitrate reductase: refined structure of the cytochrome b reductase fragment at 2.5 A, its ADP complex and an active-site mutant and modeling of the cytochrome b domain.
J.Mol.Biol., 248, 1995
1CNF
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STRUCTURAL STUDIES ON CORN NITRATE REDUCTASE: REFINED STRUCTURE OF THE CYTOCHROME B REDUCTASE FRAGMENT AT 2.5 ANGSTROMS, ITS ADP COMPLEX AND AN ACTIVE SITE MUTANT AND MODELING OF THE CYTOCHROME B DOMAIN
Descriptor:NITRATE REDUCTASE, FLAVIN-ADENINE DINUCLEOTIDE, ADENOSINE-5'-DIPHOSPHATE
Authors:Lu, G., Lindqvist, Y., Schneider, G.
Deposit date:1995-02-01
Release date:1995-04-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural studies on corn nitrate reductase: refined structure of the cytochrome b reductase fragment at 2.5 A, its ADP complex and an active-site mutant and modeling of the cytochrome b domain.
J.Mol.Biol., 248, 1995
2CND
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STRUCTURAL STUDIES ON CORN NITRATE REDUCTASE: REFINED STRUCTURE OF THE CYTOCHROME B REDUCTASE FRAGMENT AT 2.5 ANGSTROMS, ITS ADP COMPLEX AND AN ACTIVE SITE MUTANT AND MODELING OF THE CYTOCHROME B DOMAIN
Descriptor:NADH-DEPENDENT NITRATE REDUCTASE, FLAVIN-ADENINE DINUCLEOTIDE
Authors:Lu, G., Lindqvist, Y., Schneider, G.
Deposit date:1995-02-01
Release date:1995-04-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural studies on corn nitrate reductase: refined structure of the cytochrome b reductase fragment at 2.5 A, its ADP complex and an active-site mutant and modeling of the cytochrome b domain.
J.Mol.Biol., 248, 1995
1QPB
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PYRUVATE DECARBOYXLASE FROM YEAST (FORM B) COMPLEXED WITH PYRUVAMIDE
Descriptor:PYRUVATE DECARBOXYLASE (FORM B), THIAMINE DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Lu, G., Dobritzsch, D., Schneider, G.
Deposit date:1999-11-26
Release date:2000-02-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The Structural Basis of Substrate Activation in Yeast Pyruvate Decarboxylase a Crystallographic and Kinetic Study
Eur.J.Biochem., 267, 2000
1FSA
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THE T-STATE STRUCTURE OF LYS 42 TO ALA MUTANT OF THE PIG KIDNEY FRUCTOSE 1,6-BISPHOSPHATASE EXPRESSED IN E. COLI
Descriptor:FRUCTOSE 1,6-BISPHOSPHATASE, FRUCTOSE-6-PHOSPHATE, MANGANESE (II) ION, ...
Authors:Lu, G., Stec, B., Giroux, E., Kantrowitz, E.R.
Deposit date:1996-08-24
Release date:1997-09-04
Last modified:2011-11-16
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Evidence for an active T-state pig kidney fructose 1,6-bisphosphatase: interface residue Lys-42 is important for allosteric inhibition and AMP cooperativity.
Protein Sci., 5, 1996
2AWN
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CRYSTAL STRUCTURE OF THE ADP-MG-BOUND E. COLI MALK (CRYSTALLIZED WITH ATP-MG)
Descriptor:Maltose/maltodextrin import ATP-binding protein malK, MAGNESIUM ION, ADENOSINE-5'-DIPHOSPHATE
Authors:Lu, G., Westbrooks, J.M., Davidson, A.L., Chen, J.
Deposit date:2005-09-01
Release date:2005-12-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:ATP hydrolysis is required to reset the ATP-binding cassette dimer into the resting-state conformation.
Proc.Natl.Acad.Sci.Usa, 102, 2005
2AWO
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CRYSTAL STRUCTURE OF THE ADP-MG-BOUND E. COLI MALK (CRYSTALLIZED WITH ADP-MG)
Descriptor:Maltose/maltodextrin import ATP-binding protein malK, MAGNESIUM ION, ADENOSINE-5'-DIPHOSPHATE
Authors:Lu, G., Westbrooks, J.M., Davidson, A.L., Chen, J.
Deposit date:2005-09-01
Release date:2005-12-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:ATP hydrolysis is required to reset the ATP-binding cassette dimer into the resting-state conformation.
Proc.Natl.Acad.Sci.Usa, 102, 2005
2KV8
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SOLUTION STRUCTURE OFRGS12 PDZ DOMAIN
Descriptor:Regulator of G-protein signaling 12
Authors:Lu, G., Ji, P., Huang, H.
Deposit date:2010-03-10
Release date:2011-03-02
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Determining the Molecular Basis for the pH-dependent Interaction between the PDZ of Human RGS12 and MEK2
To be Published
3Q0L
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CRYSTAL STRUCTURE OF THE PUMILIO-HOMOLOGY DOMAIN FROM HUMAN PUMILIO1 IN COMPLEX WITH P38ALPHA NREA
Descriptor:Pumilio homolog 1, 5'-R(UP*GP*UP*AP*AP*AP*UP*A)-3'
Authors:Lu, G., Hall, T.M.T.
Deposit date:2010-12-15
Release date:2011-03-16
Last modified:2013-06-19
Method:X-RAY DIFFRACTION (2.503 Å)
Cite:Alternate modes of cognate RNA recognition by human PUMILIO proteins.
Structure, 19, 2011
3Q0M
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CRYSTAL STRUCTURE OF THE PUMILIO-HOMOLOGY DOMAIN FROM HUMAN PUMILIO1 IN COMPLEX WITH P38ALPHA NREB
Descriptor:Pumilio homolog 1, 5'-R(UP*GP*UP*AP*GP*AP*UP*A)-3'
Authors:Lu, G., Hall, T.M.T.
Deposit date:2010-12-15
Release date:2011-03-16
Last modified:2013-06-19
Method:X-RAY DIFFRACTION (2.705 Å)
Cite:Alternate modes of cognate RNA recognition by human PUMILIO proteins.
Structure, 19, 2011
3Q0N
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CRYSTAL STRUCTURE OF THE PUMILIO-HOMOLOGY DOMAIN FROM HUMAN PUMILIO1 IN COMPLEX WITH ERK2 NRE
Descriptor:Pumilio homolog 1, 5'-R(UP*GP*UP*AP*CP*AP*UP*C)-3'
Authors:Lu, G., Hall, T.M.T.
Deposit date:2010-12-15
Release date:2011-03-16
Last modified:2013-06-19
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Alternate modes of cognate RNA recognition by human PUMILIO proteins.
Structure, 19, 2011
3Q0O
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CRYSTAL STRUCTURE OF THE PUMILIO-HOMOLOGY DOMAIN FROM HUMAN PUMILIO1 IN COMPLEX WITH ERK2 NRE
Descriptor:Pumilio homolog 1, 5'-R(UP*GP*UP*AP*CP*AP*UP*C)-3'
Authors:Lu, G., Hall, T.M.T.
Deposit date:2010-12-15
Release date:2011-03-16
Last modified:2013-06-19
Method:X-RAY DIFFRACTION (2.804 Å)
Cite:Alternate modes of cognate RNA recognition by human PUMILIO proteins.
Structure, 19, 2011
3Q0P
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CRYSTAL STRUCTURE OF THE PUMILIO-HOMOLOGY DOMAIN FROM HUMAN PUMILIO1 IN COMPLEX WITH HUNCHBACK NRE
Descriptor:Pumilio homolog 1, 5'-R(UP*GP*UP*AP*UP*AP*UP*A)-3', CHLORIDE ION
Authors:Lu, G., Hall, T.M.T.
Deposit date:2010-12-15
Release date:2011-03-16
Last modified:2013-06-19
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Alternate modes of cognate RNA recognition by human PUMILIO proteins.
Structure, 19, 2011
3Q0Q
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CRYSTAL STRUCTURE OF THE PUMILIO-HOMOLOGY DOMAIN FROM HUMAN PUMILIO2 IN COMPLEX WITH P38ALPHA NREA
Descriptor:Pumilio homolog 2, 5'-R(UP*GP*UP*AP*AP*AP*UP*A)-3'
Authors:Lu, G., Hall, T.M.T.
Deposit date:2010-12-15
Release date:2011-03-16
Last modified:2013-06-19
Method:X-RAY DIFFRACTION (2 Å)
Cite:Alternate modes of cognate RNA recognition by human PUMILIO proteins.
Structure, 19, 2011
3Q0R
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CRYSTAL STRUCTURE OF THE PUMILIO-HOMOLOGY DOMAIN FROM HUMAN PUMILIO2 IN COMPLEX WITH P38ALPHA NREB
Descriptor:Pumilio homolog 2, 5'-R(UP*GP*UP*AP*GP*AP*UP*A)-3'
Authors:Lu, G., Hall, T.M.T.
Deposit date:2010-12-15
Release date:2011-03-16
Last modified:2013-06-19
Method:X-RAY DIFFRACTION (2 Å)
Cite:Alternate modes of cognate RNA recognition by human PUMILIO proteins.
Structure, 19, 2011
3Q0S
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CRYSTAL STRUCTURE OF THE PUMILIO-HOMOLOGY DOMAIN FROM HUMAN PUMILIO2 IN COMPLEX WITH ERK2 NRE
Descriptor:Pumilio homolog 2, 5'-R(UP*GP*UP*AP*CP*AP*UP*C)-3'
Authors:Lu, G., Hall, T.M.T.
Deposit date:2010-12-15
Release date:2011-03-16
Last modified:2013-06-19
Method:X-RAY DIFFRACTION (2 Å)
Cite:Alternate modes of cognate RNA recognition by human PUMILIO proteins.
Structure, 19, 2011
3RE9
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CRYSTAL STRUCTURE OF SORTASEC1 FROM STREPTOCOCCUS SUIS
Descriptor:Sortase-like protein
Authors:Lu, G., Qi, J., Gao, F., Yan, J., Tang, J., Gao, G.F.
Deposit date:2011-04-04
Release date:2011-06-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:A novel "open-form" structure of sortaseC from Streptococcus suis
Proteins, 2011
3SJ8
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CRYSTAL STRUCTURE OF THE 3C PROTEASE FROM COXSACKIEVIRUS A16
Descriptor:3C protease
Authors:Lu, G., Qi, J., Chen, Z., Xu, X., Gao, F., Lin, D., Qian, W., Liu, H., Jiang, H., Yan, J., Gao, G.F.
Deposit date:2011-06-21
Release date:2011-08-10
Last modified:2011-09-28
Method:X-RAY DIFFRACTION (2.199 Å)
Cite:Enterovirus 71 and Coxsackievirus A16 3C Proteases: Binding to Rupintrivir and Their Substrates and Anti-Hand, Foot, and Mouth Disease Virus Drug Design.
J.Virol., 85, 2011
3SJ9
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CRYSTAL STRUCTURE OF THE C147A MUTANT 3C OF CVA16 IN COMPLEX WITH FAGLRQAVTQ PEPTIDE
Descriptor:3C protease, FAGLRQAVTQ peptide
Authors:Lu, G., Qi, J., Chen, Z., Xu, X., Gao, F., Lin, D., Qian, W., Liu, H., Jiang, H., Yan, J., Gao, G.F.
Deposit date:2011-06-21
Release date:2011-08-10
Last modified:2011-09-28
Method:X-RAY DIFFRACTION (2.399 Å)
Cite:Enterovirus 71 and Coxsackievirus A16 3C Proteases: Binding to Rupintrivir and Their Substrates and Anti-Hand, Foot, and Mouth Disease Virus Drug Design.
J.Virol., 85, 2011
3SJI
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CRYSTAL STRUCTURE OF CVA16 3C IN COMPLEX WITH RUPINTRIVIR (AG7088)
Descriptor:3C protease, 4-{2-(4-FLUORO-BENZYL)-6-METHYL-5-[(5-METHYL-ISOXAZOLE-3-CARBONYL)-AMINO]-4-OXO-HEPTANOYLAMINO}-5-(2-OXO-PYRROLIDIN-3-YL)-PENTANOIC ACID ETHYL ESTER, SODIUM ION
Authors:Lu, G., Qi, J., Chen, Z., Xu, X., Gao, F., Lin, D., Qian, W., Liu, H., Jiang, H., Yan, J., Gao, G.F.
Deposit date:2011-06-21
Release date:2011-08-10
Last modified:2011-09-28
Method:X-RAY DIFFRACTION (1.798 Å)
Cite:Enterovirus 71 and Coxsackievirus A16 3C Proteases: Binding to Rupintrivir and Their Substrates and Anti-Hand, Foot, and Mouth Disease Virus Drug Design.
J.Virol., 85, 2011
3SJK
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CRYSTAL STRUCTURE OF THE C147A MUTANT 3C FROM ENTEROVIRUS 71
Descriptor:3C protease, KPVLRTATVQGPSLDF peptide
Authors:Lu, G., Qi, J., Chen, Z., Xu, X., Gao, F., Lin, D., Qian, W., Liu, H., Jiang, H., Yan, J., Gao, G.F.
Deposit date:2011-06-21
Release date:2011-08-10
Last modified:2011-09-28
Method:X-RAY DIFFRACTION (2.096 Å)
Cite:Enterovirus 71 and Coxsackievirus A16 3C Proteases: Binding to Rupintrivir and Their Substrates and Anti-Hand, Foot, and Mouth Disease Virus Drug Design.
J.Virol., 85, 2011
3SJO
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STRUCTURE OF EV71 3C IN COMPLEX WITH RUPINTRIVIR (AG7088)
Descriptor:3C protease, 4-{2-(4-FLUORO-BENZYL)-6-METHYL-5-[(5-METHYL-ISOXAZOLE-3-CARBONYL)-AMINO]-4-OXO-HEPTANOYLAMINO}-5-(2-OXO-PYRROLIDIN-3-YL)-PENTANOIC ACID ETHYL ESTER
Authors:Lu, G., Qi, J., Chen, Z., Xu, X., Gao, F., Lin, D., Qian, W., Liu, H., Jiang, H., Yan, J., Gao, G.F.
Deposit date:2011-06-21
Release date:2011-08-10
Last modified:2011-09-28
Method:X-RAY DIFFRACTION (1.702 Å)
Cite:Enterovirus 71 and Coxsackievirus A16 3C Proteases: Binding to Rupintrivir and Their Substrates and Anti-Hand, Foot, and Mouth Disease Virus Drug Design.
J.Virol., 85, 2011
4JL7
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CRYSTAL STRUCTURE OF THE CHEMOKINE RECEPTOR CXCR2 IN COMPLEX WITH THE FIRST PDZ DOMAIN OF NHERF1
Descriptor:Na(+)/H(+) exchange regulatory cofactor NHE-RF1, CHLORIDE ION
Authors:Lu, G., Wu, Y., Jiang, Y., Brunzelle, J., Sirinupong, N., Li, C., Yang, Z.
Deposit date:2013-03-12
Release date:2013-10-23
Method:X-RAY DIFFRACTION (1.16 Å)
Cite:Structural Insights into Neutrophilic Migration Revealed by the Crystal Structure of the Chemokine Receptor CXCR2 in Complex with the First PDZ Domain of NHERF1.
Plos One, 8, 2013
4K6M
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CRYSTAL STRUCTURE OF THE FULL-LENGTH JAPANESE ENCEPHALITIS VIRUS NS5
Descriptor:Polyprotein, S-ADENOSYL-L-HOMOCYSTEINE, SULFATE ION, ...
Authors:Lu, G., Gong, P.
Deposit date:2013-04-16
Release date:2013-08-28
Last modified:2014-01-22
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal Structure of the full-length Japanese encephalitis virus NS5 reveals a conserved methyltransferase-polymerase interface
Plos Pathog., 9, 2013
4KQZ
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STRUCTURE OF THE RECEPTOR BINDING DOMAIN (RBD) OF MERS-COV SPIKE
Descriptor:S protein, N-ACETYL-D-GLUCOSAMINE
Authors:Lu, G., Hu, Y., Wang, Q., Qi, J., Gao, F., Li, Y., Zhang, Y., Zhang, W., Yuan, Y., Bao, J., Zhang, B., Shi, Y., Yan, J., Gao, G.F.
Deposit date:2013-05-15
Release date:2013-07-10
Last modified:2013-08-14
Method:X-RAY DIFFRACTION (2.514 Å)
Cite:Molecular basis of binding between novel human coronavirus MERS-CoV and its receptor CD26
Nature, 500, 2013