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1HND
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CRYSTAL STRUCTURE OF BETA-KETOACYL-ACP SYNTHASE III-COA COMPLEX
Descriptor:BETA-KETOACYL-ACYL CARRIER PROTEIN SYNTHASE III, COENZYME A
Authors:Qiu, X., Janson, C.A., Smith, W.W., Head, M., Lonsdale, J., Konstantinidis, A.K.
Deposit date:2000-12-07
Release date:2000-12-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Refined structures of beta-ketoacyl-acyl carrier protein synthase III.
J.Mol.Biol., 307, 2001
1HNH
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CRYSTAL STRUCTURE OF BETA-KETOACYL-ACP SYNTHASE III + DEGRADED FORM OF ACETYL-COA
Descriptor:BETA-KETOACYL-ACYL CARRIER PROTEIN SYNTHASE III, COENZYME A
Authors:Qiu, X., Janson, C.A., Smith, W.W., Head, M., Lonsdale, J., Konstantinidis, A.K.
Deposit date:2000-12-07
Release date:2000-12-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Refined structures of beta-ketoacyl-acyl carrier protein synthase III.
J.Mol.Biol., 307, 2001
1HNJ
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CRYSTAL STRUCTURE OF BETA-KETOACYL-ACP SYNTHASE III + MALONYL-COA
Descriptor:BETA-KETOACYL-ACYL CARRIER PROTEIN SYNTHASE III, PHOSPHATE ION, MALONYL-COENZYME A
Authors:Qiu, X., Janson, C.A., Smith, W.W., Head, M., Lonsdale, J., Konstantinidis, A.K.
Deposit date:2000-12-07
Release date:2000-12-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.46 Å)
Cite:Refined structures of beta-ketoacyl-acyl carrier protein synthase III.
J.Mol.Biol., 307, 2001
1HNK
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CRYSTAL STRUCTURE OF BETA-KETOACYL-ACP SYNTHASE III, APO TETRAGONAL FORM
Descriptor:BETA-KETOACYL-ACYL CARRIER PROTEIN SYNTHASE III
Authors:Qiu, X., Janson, C.A., Smith, W.W., Head, M., Lonsdale, J., Konstantinidis, A.K.
Deposit date:2000-12-07
Release date:2000-12-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Refined structures of beta-ketoacyl-acyl carrier protein synthase III.
J.Mol.Biol., 307, 2001
1HN9
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CRYSTAL STRUCTURE OF BETA-KETOACYL-ACP SYNTHASE III
Descriptor:BETA-KETOACYL-ACYL CARRIER PROTEIN SYNTHASE III, PHOSPHATE ION
Authors:Qiu, X., Janson, C.A., Konstantinidis, A.K., Nwagwu, S., Silverman, C., Smith, W.W., Khandekar, S.K., Lonsdale, J., Abdel-Meguid, S.S.
Deposit date:2000-12-07
Release date:2000-12-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of beta-ketoacyl-acyl carrier protein synthase III. A key condensing enzyme in bacterial fatty acid biosynthesis.
J.Biol.Chem., 274, 1999
2AQ7
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STRUCTURE-ACTIVITY RELATIONSHIPS AT THE 5-POSIITON OF THIOLACTOMYCIN: AN INTACT 5(R)-ISOPRENE UNIT IS REQUIRED FOR ACTIVITY AGAINST THE CONDENSING ENZYMES FROM MYCOBACTERIUM TUBERCULOSIS AND ESCHERICHIA COLI
Descriptor:3-oxoacyl-[acyl-carrier-protein] synthase I, (5R)-4-HYDROXY-3,5-DIMETHYL-5-[(1E,3E)-2-METHYLPENTA-1,3-DIENYL]THIOPHEN-2(5H)-ONE
Authors:Kim, P., Zhang, Y.M., Shenoy, G., Nguyen, Q.A., Boshoff, H.I., Manjunatha, U.H., Goodwin, M.B., Lonsdale, J., Price, A.C., Miller, D.J.
Deposit date:2005-08-17
Release date:2006-01-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure-Activity Relationships at the 5-Position of Thiolactomycin: An Intact (5R)-Isoprene Unit Is Required for Activity against the Condensing Enzymes from Mycobacterium tuberculosis and Escherichia coli
J.Med.Chem., 49, 2006
2AQB
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STRUCTURE-ACTIVITY RELATIONSHIPS AT THE 5-POSITION OF THIOLACTOMYCIN: AN INTACT 5(R)-ISOPRENE UNIT IS REQUIRED FOR ACTIVITY AGAINST THE CONDENSING ENZYMES FROM MYCOBACTERIUM TUBERCULOSIS AND ESCHERCHIA COLI
Descriptor:3-oxoacyl-[acyl-carrier-protein] synthase I, (5R)-5-[(1E)-BUTA-1,3-DIENYL]-4-HYDROXY-3,5-DIMETHYLTHIOPHEN-2(5H)-ONE
Authors:Kim, P., Zhang, Y.M., Shenoy, G., Nguyen, Q.A., Boshoff, H.I., Manjunatha, U.H., Goodwin, M.B., Lonsdale, J., Price, A.C., Miller, D.J.
Deposit date:2005-08-17
Release date:2006-01-17
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:Structure-Activity Relationships at the 5-Position of Thiolactomycin: An Intact (5R)-Isoprene Unit Is Required for Activity against the Condensing Enzymes from Mycobacterium tuberculosis and Escherichia coli
J.Med.Chem., 49, 2006