Author results

2AB5
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BI3 LAGLIDADG MATURASE
Descriptor:mRNA maturase, SULFATE ION
Authors:Longo, A., Leonard, C.W., Bassi, G.S., Berndt, D., Krahn, J.M., Hall, T.M., Weeks, K.M.
Deposit date:2005-07-14
Release date:2005-08-30
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Evolution from DNA to RNA recognition by the bI3 LAGLIDADG maturase
Nat.Struct.Mol.Biol., 12, 2005
2H1K
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CRYSTAL STRUCTURE OF THE PDX1 HOMEODOMAIN IN COMPLEX WITH DNA
Descriptor:15-mer DNA, Pancreatic and duodenal homeobox 1
Authors:Longo, A., Guanga, G.P., Rose, R.B.
Deposit date:2006-05-16
Release date:2007-03-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.42 Å)
Cite:Structural basis for induced fit mechanisms in DNA recognition by the pdx1 homeodomain
Biochemistry, 46, 2007
2QL2
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CRYSTAL STRUCTURE OF THE BASIC-HELIX-LOOP-HELIX DOMAINS OF THE HETERODIMER E47/NEUROD1 BOUND TO DNA
Descriptor:Transcription factor E2-alpha, Neurogenic differentiation factor 1, DNA (5'-D(*DTP*DAP*DGP*DGP*DCP*DCP*DAP*DTP*DCP*DTP*DGP*DGP*DTP*DCP*DCP*DT)-3'), ...
Authors:Rose, R.B., Longo, A., Guanga, G.P.
Deposit date:2007-07-12
Release date:2008-11-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of E47-NeuroD1/beta2 bHLH domain-DNA complex: heterodimer selectivity and DNA recognition.
Biochemistry, 47, 2008
2BPM
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STRUCTURE OF CDK2-CYCLIN A WITH PHA-630529
Descriptor:CELL DIVISION PROTEIN KINASE 2, CYCLIN A2, (2S)-N-[(3Z)-5-CYCLOPROPYL-3H-PYRAZOL-3-YLIDENE]-2-[4-(2-OXOIMIDAZOLIDIN-1-YL)PHENYL]PROPANAMIDE, ...
Authors:Cameron, A., Fogliatto, G., Pevarello, P., Brasca, M.G., Orsini, P., Traquandi, G., Longo, A., Nesi, M., Orzi, F., Piutti, C., Sansonna, P., Varasi, M., Vulpetti, A., Roletto, F., Alzani, R., Ciomei, M., Albanese, C., Pastori, W., Marsiglio, A., Pesenti, E., Fiorentini, F., Bischoff, J.R., Mercurio, C.
Deposit date:2005-04-21
Release date:2005-12-08
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:3-Aminopyrazole Inhibitors of Cdk2-Cyclin a as Antitumor Agents. 2. Lead Optimization
J.Med.Chem., 48, 2005
2WXV
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STRUCTURE OF CDK2-CYCLIN A WITH A PYRAZOLO(4,3-H) QUINAZOLINE-3- CARBOXAMIDE INHIBITOR
Descriptor:CELL DIVISION PROTEIN KINASE 2, CYCLIN-A2, N,1-DIMETHYL-8-{[1-(METHYLSULFONYL)PIPERIDIN-4-YL]AMINO}-1H-PYRAZOLO[4,3-H]QUINAZOLINE-3-CARBOXAMIDE, ...
Authors:Traquandi, G., Ciomei, M., Ballinari, D., Casale, E., Colombo, N., Croci, V., Fiorentini, F., Isacchi, A., Longo, A., Mercurio, C., Panzeri, A., Pastori, W., Pevarello, P., Volpi, D., Roussel, P., Vulpetti, A., Brasca, M.G.
Deposit date:2009-11-10
Release date:2010-02-23
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Identification of Potent Pyrazolo[4,3-H]Quinazoline-3-Carboxamides as Multi-Cyclin-Dependent Kinase Inhibitors.
J.Med.Chem., 53, 2010