Author results

5CGY
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FAB FRAGMENT OF CHIKUNGUNYA VIRUS NEUTRALIZING HUMAN MONOCLONAL ANTIBODY 4J21
Descriptor:Heavy Chain of Fab, Light Chain of Fab
Authors:Long, F., Crowe, J.E., Rossmann, M.G.
Deposit date:2015-07-09
Release date:2015-11-11
Last modified:2015-11-18
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:Cryo-EM structures elucidate neutralizing mechanisms of anti-chikungunya human monoclonal antibodies with therapeutic activity.
Proc.Natl.Acad.Sci.USA, 112, 2015
5CHN
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FAB FRAGMENTS OF CHIKUNGUNYA VIRUS NEUTRALIZING HUMAN MONOCLONAL ANTIBODY 5M16
Descriptor:Fab Heavy Chain, Fab Light Chain
Authors:Long, F., Crowe, J.E., Rossmann, M.G.
Deposit date:2015-07-10
Release date:2015-11-11
Last modified:2015-11-25
Method:X-RAY DIFFRACTION (2.047 Å)
Cite:Cryo-EM structures elucidate neutralizing mechanisms of anti-chikungunya human monoclonal antibodies with therapeutic activity.
Proc.Natl.Acad.Sci.USA, 112, 2015
3BCG
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CONFORMATIONAL CHANGES OF THE ACRR REGULATOR REVEAL A MECHANISM OF INDUCTION
Descriptor:HTH-type transcriptional regulator acrR
Authors:Gu, R., Li, M., Su, C.C., Long, F., Yang, F., McDermott, G., Yu, E.Y.
Deposit date:2007-11-12
Release date:2008-02-26
Last modified:2009-02-24
Method:X-RAY DIFFRACTION (2.48 Å)
Cite:Conformational change of the AcrR regulator reveals a possible mechanism of induction.
Acta Crystallogr.,Sect.F, 64, 2008
3H94
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CRYSTAL STRUCTURE OF THE MEMBRANE FUSION PROTEIN CUSB FROM ESCHERICHIA COLI
Descriptor:Cation efflux system protein cusB
Authors:Su, C.-C., Yang, F., Long, F., Reyon, D., Routh, M.D., Kuo, D.W., Mokhtari, A.K., Van Ornam, J.D., Rabe, K.L., Hoy, J.A., Lee, Y.J., Rajashankar, K.R., Yu, E.W.
Deposit date:2009-04-30
Release date:2009-08-18
Last modified:2009-10-20
Method:X-RAY DIFFRACTION (3.84 Å)
Cite:Crystal structure of the membrane fusion protein CusB from Escherichia coli
J.Mol.Biol., 393, 2009
3OOC
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CRYSTAL STRUCTURE OF THE MEMBRANE FUSION PROTEIN CUSB FROM ESCHERICHIA COLI
Descriptor:Cation efflux system protein cusB
Authors:Su, C.-C., Yang, F., Long, F., Reyon, D., Routh, M.D., Kuo, D.W., Mokhtari, A.K., Van Ornam, J.D., Rabe, K.L., Hoy, J.A., Lee, Y.J., Rajashankar, K.R., Yu, E.W.
Deposit date:2010-08-30
Release date:2010-12-29
Method:X-RAY DIFFRACTION (3.404 Å)
Cite:Crystal structure of the membrane fusion protein CusB from Escherichia coli.
J.Mol.Biol., 393, 2009
2MXU
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42-RESIDUE BETA AMYLOID FIBRIL
Descriptor:Amyloid beta A4 protein
Authors:Xiao, Y., Ma, B., McElheny, D., Parthasarathy, S., Long, F., Hoshi, M., Nussinov, R., Ishii, Y.
Deposit date:2015-01-14
Release date:2015-05-06
Last modified:2015-06-17
Method:SOLID-STATE NMR
Cite:A beta (1-42) fibril structure illuminates self-recognition and replication of amyloid in Alzheimer's disease.
Nat.Struct.Mol.Biol., 22, 2015
3F31
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CRYSTAL STRUCTURE OF THE N-TERMINAL REGION OF ALPHAII-SPECTRIN TETRAMERIZATION DOMAIN
Descriptor:Spectrin alpha chain, brain
Authors:Mehboob, S., Santarsiero, B.D., Long, F., Witek, M., Fung, L.W.
Deposit date:2008-10-30
Release date:2009-10-13
Last modified:2010-05-19
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of the nonerythroid alpha-spectrin tetramerization site reveals differences between erythroid and nonerythroid spectrin tetramer formation.
J.Biol.Chem., 285, 2010
3J6B
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STRUCTURE OF THE YEAST MITOCHONDRIAL LARGE RIBOSOMAL SUBUNIT
Descriptor:PROTEIN/RNA Complex
Authors:Amunts, A., Brown, A., Bai, X.C., Llacer, J.L., Hussain, T., Emsley, P., Long, F., Murshudov, G., Scheres, S.H.W., Ramakrishnan, V.
Deposit date:2014-01-22
Release date:2014-04-09
Last modified:2014-12-17
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structure of the yeast mitochondrial large ribosomal subunit.
Science, 343, 2014
3T51
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CRYSTAL STRUCTURES OF THE PRE-EXTRUSION AND EXTRUSION STATES OF THE CUSBA ADAPTOR-TRANSPORTER COMPLEX
Descriptor:Cation efflux system protein CusB, Cation efflux system protein CusA
Authors:Su, C.-C., Long, F., Yu, E.W.
Deposit date:2011-07-26
Release date:2012-06-20
Last modified:2012-09-05
Method:X-RAY DIFFRACTION (3.9 Å)
Cite:Charged Amino Acids (R83, E567, D617, E625, R669, and K678) of CusA Are Required for Metal Ion Transport in the Cus Efflux System.
J.Mol.Biol., 422, 2012
3T53
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CRYSTAL STRUCTURES OF THE EXTRUSION STATE OF THE CUSBA ADAPTOR-TRANSPORTER COMPLEX
Descriptor:Cation efflux system protein CusB, Cation efflux system protein CusA
Authors:Su, C.-C., Long, F., Yu, E.W.
Deposit date:2011-07-26
Release date:2012-06-20
Last modified:2012-09-05
Method:X-RAY DIFFRACTION (3.37 Å)
Cite:Charged Amino Acids (R83, E567, D617, E625, R669, and K678) of CusA Are Required for Metal Ion Transport in the Cus Efflux System.
J.Mol.Biol., 422, 2012
3T56
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CRYSTAL STRUCTURE OF THE PRE-EXTRUSION STATE OF THE CUSBA ADAPTOR-TRANSPORTER COMPLEX
Descriptor:Cation efflux system protein CusA, Cation efflux system protein CusB
Authors:Su, C.-C., Long, F., Yu, E.W.
Deposit date:2011-07-26
Release date:2012-06-20
Last modified:2012-09-05
Method:X-RAY DIFFRACTION (3.42 Å)
Cite:Charged Amino Acids (R83, E567, D617, E625, R669, and K678) of CusA Are Required for Metal Ion Transport in the Cus Efflux System.
J.Mol.Biol., 422, 2012
4DNR
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CRYSTAL STRUCTURE OF THE CUSBA HEAVY-METAL EFFLUX COMPLEX FROM ESCHERICHIA COLI, E716F MUTANT
Descriptor:Cation efflux system protein CusB, Cation efflux system protein CusA
Authors:Su, C.-C., Long, F., Yu, E.
Deposit date:2012-02-08
Release date:2013-02-13
Method:X-RAY DIFFRACTION (3.68 Å)
Cite:Crystal structures of the pre-extrusion and extrusion states of the CusBA adaptor-transporter complex
To be Published
4DNT
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CRYSTAL STRUCTURE OF THE CUSBA HEAVY-METAL EFFLUX COMPLEX FROM ESCHERICHIA COLI, MUTANT
Descriptor:Cation efflux system protein CusB, Cation efflux system protein CusA
Authors:Su, C.-C., Long, F., Yu, E.
Deposit date:2012-02-09
Release date:2012-06-20
Last modified:2012-09-05
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Charged Amino Acids (R83, E567, D617, E625, R669, and K678) of CusA Are Required for Metal Ion Transport in the Cus Efflux System.
J.Mol.Biol., 422, 2012
4DOP
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CRYSTAL STRUCTURE OF THE CUSBA HEAVY-METAL EFFLUX COMPLEX FROM ESCHERICHIA COLI, R MUTANT
Descriptor:Cation efflux system protein CusB, Cation efflux system protein CusA
Authors:Su, C.-C., Long, F., Yu, E.
Deposit date:2012-02-10
Release date:2012-06-20
Last modified:2012-09-05
Method:X-RAY DIFFRACTION (4.2 Å)
Cite:Charged Amino Acids (R83, E567, D617, E625, R669, and K678) of CusA Are Required for Metal Ion Transport in the Cus Efflux System.
J.Mol.Biol., 422, 2012
4WM7
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CRYSTAL STRUCTURE OF HUMAN ENTEROVIRUS D68 IN COMPLEX WITH PLECONARIL
Descriptor:Enterovirus D68 capsid VP1, Enterovirus D68 capsid VP2, Enterovirus D68 capsid VP3, Enterovirus D68 capsid VP4
Authors:Liu, Y., Sheng, J., Fokine, A., Meng, G., Long, F., Kuhn, R.J., Rossmann, M.G.
Deposit date:2014-10-08
Release date:2015-01-14
Last modified:2015-02-25
Method:X-RAY DIFFRACTION (2.32 Å)
Cite:Virus structure. Structure and inhibition of EV-D68, a virus that causes respiratory illness in children.
Science, 347, 2015
4WM8
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CRYSTAL STRUCTURE OF HUMAN ENTEROVIRUS D68
Descriptor:Enterovirus D68 capsid VP1, Enterovirus D68 capsid VP2, Enterovirus D68 capsid VP3, Enterovirus D68 capsid VP4
Authors:Liu, Y., Sheng, J., Fokine, A., Meng, G., Long, F., Kuhn, R.J., Rossmann, M.G.
Deposit date:2014-10-08
Release date:2015-01-14
Last modified:2015-02-25
Method:X-RAY DIFFRACTION (2 Å)
Cite:Virus structure. Structure and inhibition of EV-D68, a virus that causes respiratory illness in children.
Science, 347, 2015
5ANY
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ELECTRON CRYO-MICROSCOPY OF CHIKUNGUNYA VIRUS IN COMPLEX WITH NEUTRALIZING ANTIBODY FAB CHK265
Descriptor:E1, E2, FAB CHK265
Authors:Fox, J.M., Long, F., Edeling, M.A., Lin, H., Duijl-Richter, M., Fong, R.H., Kahle, K.M., Smit, J.M., Jin, J., Simmons, G., Doranz, B.J., Crowe, J.E., Fremont, D.H., Rossmann, M.G., Diamond, M.S.
Deposit date:2015-09-08
Release date:2015-11-25
Last modified:2015-12-09
Method:ELECTRON MICROSCOPY (16.9 Å)
Cite:Broadly Neutralizing Alphavirus Antibodies Bind an Epitope on E2 and Inhibit Entry and Egress.
Cell(Cambridge,Mass.), 163, 2015
5UHY
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A HUMAN ANTIBODY AGAINST ZIKA VIRUS CROSSLINKS THE E PROTEIN TO PREVENT INFECTION
Descriptor:ZV67 Fab chain 1, ZV67 Fab chain 2, envelope protein
Authors:Hasan, S.S., Miller, A., Sapparapu, G., Fernandez, E., Klose, T., Long, F., Fokine, A., Porta, J.C., Jiang, W., Diamond, M.S., Crowe Jr., J.E., Kuhn, R.J., Rossmann, M.G.
Deposit date:2017-01-12
Release date:2017-03-29
Method:ELECTRON MICROSCOPY (6.2 Å)
Cite:A human antibody against Zika virus crosslinks the E protein to prevent infection.
Nat Commun, 8, 2017
3K07
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CRYSTAL STRUCTURE OF CUSA
Descriptor:Cation efflux system protein cusA
Authors:Su, C.-C.
Deposit date:2009-09-24
Release date:2010-09-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.521 Å)
Cite:Crystal structures of the CusA efflux pump suggest methionine-mediated metal transport.
Nature, 467, 2010
3K0I
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CRYSTAL STRUCTURE OF CU(I)CUSA
Descriptor:Cation efflux system protein cusA
Authors:Su, C.-C.
Deposit date:2009-09-24
Release date:2010-10-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (4.116 Å)
Cite:Crystal structure of CusA
To be Published
3KSO
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STRUCTURE AND MECHANISM OF THE HEAVY METAL TRANSPORTER CUSA
Descriptor:Cation efflux system protein cusA
Authors:Su, C.-C.
Deposit date:2009-11-23
Release date:2010-09-22
Last modified:2010-10-13
Method:X-RAY DIFFRACTION (4.367 Å)
Cite:Crystal structures of the CusA efflux pump suggest methionine-mediated metal transport.
Nature, 467, 2010
3KSS
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STRUCTURE AND MECHANISM OF THE HEAVY METAL TRANSPORTER CUSA
Descriptor:Cation efflux system protein cusA
Authors:Su, C.-C.
Deposit date:2009-11-23
Release date:2010-09-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.88 Å)
Cite:Crystal structures of the CusA efflux pump suggest methionine-mediated metal transport.
Nature, 467, 2010
3HGG
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CRYSTAL STRUCTURE OF CMER BOUND TO CHOLIC ACID
Descriptor:CmeR
Authors:Routh, M.D., Yang, F.
Deposit date:2009-05-13
Release date:2010-06-30
Method:X-RAY DIFFRACTION (2.57 Å)
Cite:Structural basis for anionic ligand recognition by multidrug binding proteins: Crystal structures of CmeR-bile acid complexes
To be Published
3OPO
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CRYSTAL STRUCTURE OF THE MEMBRANE FUSION PROTEIN CUSB FROM ESCHERICHIA COLI
Descriptor:Cation efflux system protein cusB
Authors:Su, C.-C.
Deposit date:2010-09-01
Release date:2011-04-27
Method:X-RAY DIFFRACTION (3.848 Å)
Cite:Crystal structure of the membrane fusion protein CusB from Escherichia coli.
J.Mol.Biol., 393, 2009
3OW7
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CRYSTAL STRUCTURE OF THE MEMBRANE FUSION PROTEIN CUSB FROM ESCHERICHIA COLI.
Descriptor:Cation efflux system protein cusB
Authors:Su, C.-C.
Deposit date:2010-09-17
Release date:2010-11-17
Method:X-RAY DIFFRACTION (3.78 Å)
Cite:Crystal structure of the membrane fusion protein CusB from Escherichia coli.
J.Mol.Biol., 393, 2009
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