Author results

6MID
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CRYO-EM STRUCTURE OF THE ZIKV VIRION IN COMPLEX WITH FAB FRAGMENTS OF THE POTENTLY NEUTRALIZING HUMAN MONOCLONAL ANTIBODY ZIKV-195
Descriptor:E protein, M protein, monoclonal antibody ZIKV-195 heavy chain, ...
Authors:Long, F., Rossmann, M.G.
Deposit date:2018-09-19
Release date:2019-01-16
Last modified:2019-02-13
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Structural basis of a potent human monoclonal antibody against Zika virus targeting a quaternary epitope.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
6CO8
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STRUCTURE OF ZIKA VIRUS AT A RESOLUTION OF 3.1 ANGSTROM
Descriptor:E protein, M protein, N-ACETYL-D-GLUCOSAMINE
Authors:Sevvana, M., Long, F., Miller, A.J., Klose, T., Buda, G., Sun, L., Kuhn, R.J., Rossmann, M.R.
Deposit date:2018-03-12
Release date:2018-07-04
Last modified:2018-09-19
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Refinement and Analysis of the Mature Zika Virus Cryo-EM Structure at 3.1 angstrom Resolution.
Structure, 26, 2018
5X6B
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CRYSTAL STRUCTURE OF SEPCYSE-SEPCYSS IN COMPLEX WITH TRNACYS FROM METHANOCALDOCOCCUS JANNASCHII
Descriptor:O-phospho-L-seryl-tRNA:Cys-tRNA synthase, Uncharacterized protein MJ1481, tRNACys
Authors:Chen, M., Kato, K., Yao, M.
Deposit date:2017-02-21
Release date:2017-12-06
Method:X-RAY DIFFRACTION (2.596 Å)
Cite:Structural basis for tRNA-dependent cysteine biosynthesis
Nat Commun, 8, 2017
5X6C
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CRYSTAL STRUCTURE OF SEPRS-SEPCYSE FROM METHANOCALDOCOCCUS JANNASCHII
Descriptor:O-phosphoserine--tRNA(Cys) ligase, Uncharacterized protein MJ1481, ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Chen, M., Kato, K., Yao, M.
Deposit date:2017-02-21
Release date:2017-12-06
Method:X-RAY DIFFRACTION (3.101 Å)
Cite:Structural basis for tRNA-dependent cysteine biosynthesis
Nat Commun, 8, 2017
5UHY
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A HUMAN ANTIBODY AGAINST ZIKA VIRUS CROSSLINKS THE E PROTEIN TO PREVENT INFECTION
Descriptor:ZV67 Fab chain 1, ZV67 Fab chain 2, envelope protein
Authors:Hasan, S.S., Miller, A., Sapparapu, G., Fernandez, E., Klose, T., Long, F., Fokine, A., Porta, J.C., Jiang, W., Diamond, M.S., Crowe Jr., J.E., Kuhn, R.J., Rossmann, M.G.
Deposit date:2017-01-12
Release date:2017-03-29
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (6.2 Å)
Cite:A human antibody against Zika virus crosslinks the E protein to prevent infection.
Nat Commun, 8, 2017
5ANY
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ELECTRON CRYO-MICROSCOPY OF CHIKUNGUNYA VIRUS IN COMPLEX WITH NEUTRALIZING ANTIBODY FAB CHK265
Descriptor:E1, E2, FAB CHK265, ...
Authors:Fox, J.M., Long, F., Edeling, M.A., Lin, H., Duijl-Richter, M., Fong, R.H., Kahle, K.M., Smit, J.M., Jin, J., Simmons, G., Doranz, B.J., Crowe, J.E., Fremont, D.H., Rossmann, M.G., Diamond, M.S.
Deposit date:2015-09-08
Release date:2015-11-25
Last modified:2018-10-03
Method:ELECTRON MICROSCOPY (16.9 Å)
Cite:Broadly Neutralizing Alphavirus Antibodies Bind an Epitope on E2 and Inhibit Entry and Egress.
Cell(Cambridge,Mass.), 163, 2015
5CGY
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FAB FRAGMENT OF CHIKUNGUNYA VIRUS NEUTRALIZING HUMAN MONOCLONAL ANTIBODY 4J21
Descriptor:Heavy Chain of Fab, Light Chain of Fab
Authors:Long, F., Crowe, J.E., Rossmann, M.G.
Deposit date:2015-07-09
Release date:2015-11-11
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:Cryo-EM structures elucidate neutralizing mechanisms of anti-chikungunya human monoclonal antibodies with therapeutic activity.
Proc.Natl.Acad.Sci.USA, 112, 2015
5CHN
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FAB FRAGMENTS OF CHIKUNGUNYA VIRUS NEUTRALIZING HUMAN MONOCLONAL ANTIBODY 5M16
Descriptor:Antibody 5M16 Fab Heavy Chain, Antibody 5M16 Fab Light Chain
Authors:Long, F., Crowe, J.E., Rossmann, M.G.
Deposit date:2015-07-10
Release date:2015-11-11
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (2.047 Å)
Cite:Cryo-EM structures elucidate neutralizing mechanisms of anti-chikungunya human monoclonal antibodies with therapeutic activity.
Proc.Natl.Acad.Sci.USA, 112, 2015
2MXU
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42-RESIDUE BETA AMYLOID FIBRIL
Descriptor:Amyloid beta A4 protein
Authors:Xiao, Y., Ma, B., McElheny, D., Parthasarathy, S., Long, F., Hoshi, M., Nussinov, R., Ishii, Y.
Deposit date:2015-01-14
Release date:2015-05-06
Last modified:2015-06-17
Method:SOLID-STATE NMR
Cite:A beta (1-42) fibril structure illuminates self-recognition and replication of amyloid in Alzheimer's disease.
Nat.Struct.Mol.Biol., 22, 2015
4R0C
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CRYSTAL STRUCTURE OF THE ALCANIVORAX BORKUMENSIS YDAH TRANSPORTER REVEALS AN UNUSUAL TOPOLOGY
Descriptor:AbgT putative transporter family, SODIUM ION, DODECYL-BETA-D-MALTOSIDE, ...
Authors:Su, C.-C., Bolla, J.R., Yu, E.W.
Deposit date:2014-07-30
Release date:2015-04-29
Method:X-RAY DIFFRACTION (2.963 Å)
Cite:Crystal structure of the Alcanivorax borkumensis YdaH transporter reveals an unusual topology.
Nat Commun, 6, 2015
4R1I
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STRUCTURE AND FUNCTION OF NEISSERIA GONORRHOEAE MTRF ILLUMINATES A CLASS OF ANTIMETABOLITE EFFLUX PUMPS
Descriptor:Aminobenzoyl-glutamate transporter
Authors:Su, C.-C., Bolla, J.R., Yu, E.W.
Deposit date:2014-08-06
Release date:2015-04-08
Last modified:2015-04-29
Method:X-RAY DIFFRACTION (3.959 Å)
Cite:Structure and Function of Neisseria gonorrhoeae MtrF Illuminates a Class of Antimetabolite Efflux Pumps.
Cell Rep, 11, 2015
4WM7
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CRYSTAL STRUCTURE OF HUMAN ENTEROVIRUS D68 IN COMPLEX WITH PLECONARIL
Descriptor:VP1, VP2, VP3, ...
Authors:Liu, Y., Sheng, J., Fokine, A., Meng, G., Long, F., Kuhn, R.J., Rossmann, M.G.
Deposit date:2014-10-08
Release date:2015-01-14
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (2.32 Å)
Cite:Virus structure. Structure and inhibition of EV-D68, a virus that causes respiratory illness in children.
Science, 347, 2015
4WM8
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CRYSTAL STRUCTURE OF HUMAN ENTEROVIRUS D68
Descriptor:VP1, VP2, VP3, ...
Authors:Liu, Y., Sheng, J., Fokine, A., Meng, G., Long, F., Kuhn, R.J., Rossmann, M.G.
Deposit date:2014-10-08
Release date:2015-01-14
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Virus structure. Structure and inhibition of EV-D68, a virus that causes respiratory illness in children.
Science, 347, 2015
4MT4
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CRYSTAL STRUCTURE OF THE CAMPYLOBACTER JEJUNI CMEC OUTER MEMBRANE CHANNEL
Descriptor:CmeC, (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, SULFATE ION, ...
Authors:Su, C.-C., Yu, E.W.
Deposit date:2013-09-19
Release date:2014-09-24
Last modified:2014-10-01
Method:X-RAY DIFFRACTION (2.373 Å)
Cite:Crystal structure of the Campylobacter jejuni CmeC outer membrane channel.
Protein Sci., 23, 2014
4MT0
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CRYSTAL STRUCTURE OF THE OPEN STATE OF THE NEISSERIA GONORRHOEAE MTRE OUTER MEMBRANE CHANNEL
Descriptor:MtrE protein, SULFATE ION
Authors:Su, C.-C., Bolla, J.R., Yu, E.W.
Deposit date:2013-09-18
Release date:2014-08-06
Method:X-RAY DIFFRACTION (3.292 Å)
Cite:Crystal structure of the open state of the Neisseria gonorrhoeae MtrE outer membrane channel.
Plos One, 9, 2014
4MT1
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CRYSTAL STRUCTURE OF THE NEISSERIA GONORRHOEAE MTRD INNER MEMBRANE MULTIDRUG EFFLUX PUMP
Descriptor:Drug efflux protein
Authors:Su, C.-C., Bolla, J.R., Yu, E.W.
Deposit date:2013-09-18
Release date:2014-08-06
Method:X-RAY DIFFRACTION (3.54 Å)
Cite:Crystal structure of the open state of the Neisseria gonorrhoeae MtrE outer membrane channel.
Plos One, 9, 2014
3J6B
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STRUCTURE OF THE YEAST MITOCHONDRIAL LARGE RIBOSOMAL SUBUNIT
Descriptor:21S ribosomal RNA, 54S ribosomal protein RML2, mitochondrial, ...
Authors:Amunts, A., Brown, A., Bai, X.C., Llacer, J.L., Hussain, T., Emsley, P., Long, F., Murshudov, G., Scheres, S.H.W., Ramakrishnan, V.
Deposit date:2014-01-22
Release date:2014-04-09
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structure of the yeast mitochondrial large ribosomal subunit.
Science, 343, 2014
4DNR
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CRYSTAL STRUCTURE OF THE CUSBA HEAVY-METAL EFFLUX COMPLEX FROM ESCHERICHIA COLI, E716F MUTANT
Descriptor:Cation efflux system protein CusB, Cation efflux system protein CusA, COPPER (II) ION
Authors:Su, C.-C., Long, F., Yu, E.
Deposit date:2012-02-08
Release date:2013-02-13
Method:X-RAY DIFFRACTION (3.68 Å)
Cite:Crystal structures of the pre-extrusion and extrusion states of the CusBA adaptor-transporter complex
To be Published
3V78
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CRYSTAL STRUCTURE OF TRANSCRIPTIONAL REGULATOR
Descriptor:PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY DEOR-FAMILY), ETHIDIUM
Authors:Do, S.V., Bolla, J.R., Chen, X., Yu, E.W.
Deposit date:2011-12-20
Release date:2012-12-26
Method:X-RAY DIFFRACTION (2.299 Å)
Cite:Structural and functional analysis of the transcriptional regulator Rv3066 of Mycobacterium tuberculosis.
Nucleic Acids Res., 40, 2012
3V6G
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CRYSTAL STRUCTURE OF TRANSCRIPTIONAL REGULATOR
Descriptor:PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY DEOR-FAMILY)
Authors:Do, S.V., Bolla, J.R., Chen, X., Yu, E.W.
Deposit date:2011-12-19
Release date:2012-08-08
Last modified:2012-10-24
Method:X-RAY DIFFRACTION (1.821 Å)
Cite:Structural and functional analysis of the transcriptional regulator Rv3066 of Mycobacterium tuberculosis.
Nucleic Acids Res., 40, 2012
3T51
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CRYSTAL STRUCTURES OF THE PRE-EXTRUSION AND EXTRUSION STATES OF THE CUSBA ADAPTOR-TRANSPORTER COMPLEX
Descriptor:Cation efflux system protein CusB, Cation efflux system protein CusA, COPPER (II) ION
Authors:Su, C.-C., Long, F., Yu, E.W.
Deposit date:2011-07-26
Release date:2012-06-20
Last modified:2012-09-05
Method:X-RAY DIFFRACTION (3.9 Å)
Cite:Charged Amino Acids (R83, E567, D617, E625, R669, and K678) of CusA Are Required for Metal Ion Transport in the Cus Efflux System.
J.Mol.Biol., 422, 2012
3T53
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CRYSTAL STRUCTURES OF THE EXTRUSION STATE OF THE CUSBA ADAPTOR-TRANSPORTER COMPLEX
Descriptor:Cation efflux system protein CusB, Cation efflux system protein CusA, COPPER (II) ION
Authors:Su, C.-C., Long, F., Yu, E.W.
Deposit date:2011-07-26
Release date:2012-06-20
Last modified:2012-09-05
Method:X-RAY DIFFRACTION (3.37 Å)
Cite:Charged Amino Acids (R83, E567, D617, E625, R669, and K678) of CusA Are Required for Metal Ion Transport in the Cus Efflux System.
J.Mol.Biol., 422, 2012
3T56
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CRYSTAL STRUCTURE OF THE PRE-EXTRUSION STATE OF THE CUSBA ADAPTOR-TRANSPORTER COMPLEX
Descriptor:Cation efflux system protein CusA, Cation efflux system protein CusB, COPPER (II) ION
Authors:Su, C.-C., Long, F., Yu, E.W.
Deposit date:2011-07-26
Release date:2012-06-20
Last modified:2012-09-05
Method:X-RAY DIFFRACTION (3.42 Å)
Cite:Charged Amino Acids (R83, E567, D617, E625, R669, and K678) of CusA Are Required for Metal Ion Transport in the Cus Efflux System.
J.Mol.Biol., 422, 2012
4DNT
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CRYSTAL STRUCTURE OF THE CUSBA HEAVY-METAL EFFLUX COMPLEX FROM ESCHERICHIA COLI, MUTANT
Descriptor:Cation efflux system protein CusB, Cation efflux system protein CusA
Authors:Su, C.-C., Long, F., Yu, E.
Deposit date:2012-02-09
Release date:2012-06-20
Last modified:2012-09-05
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Charged Amino Acids (R83, E567, D617, E625, R669, and K678) of CusA Are Required for Metal Ion Transport in the Cus Efflux System.
J.Mol.Biol., 422, 2012
4DOP
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CRYSTAL STRUCTURE OF THE CUSBA HEAVY-METAL EFFLUX COMPLEX FROM ESCHERICHIA COLI, R MUTANT
Descriptor:Cation efflux system protein CusB, Cation efflux system protein CusA
Authors:Su, C.-C., Long, F., Yu, E.
Deposit date:2012-02-10
Release date:2012-06-20
Last modified:2012-09-05
Method:X-RAY DIFFRACTION (4.2 Å)
Cite:Charged Amino Acids (R83, E567, D617, E625, R669, and K678) of CusA Are Required for Metal Ion Transport in the Cus Efflux System.
J.Mol.Biol., 422, 2012
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